Personal profile

Biography

I am a Research Manager with the World Mosquito Program in the Institute of Vector-Borne Disease. My research focuses on the use of Wolbachia for the biocontrol of arboviruses in Aedes aegypti. Specifically, I am investigating the use and effectiveness of new Wolbachia strains, how Wolbachia evolves in the field post-release, and how nuclear and mitochondrial genomes interact to impact mosquito fitness and Wolbachia stability.

Education/Academic qualification

Genetics & Development, PhD, Cornell University

Research area keywords

• Wolbachia
• Vector-borne disease

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Projects 2020 2024

• 1 Active

Projects per year

Dissecting nuclear-mitochondria interactions in Aedes aegypti and their effects on Wolbachia biocontrol methods

Flores, H., Dowling, D., White, C. & Simmons, C.

National Health & Medical Research Council (NHMRC)

1/01/20 → 31/12/24

Project: Research

Research Output 2005 2019

• 10 Article
• 1 Review Article

Research Output per year

Differential suppression of persistent insect specific viruses in trans-infected wMel and wMelPop-CLA Aedes-derived mosquito lines

McLean, B. J., Dainty, K. R., Flores, H. A. & O'Neill, S. L., 15 Jan 2019, In : Virology. 527, p. 141-145 5 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

38 Citations (Scopus)

Controlling vector-borne diseases by releasing modified mosquitoes

Flores, H. A. & O'Neill, S. L., 1 Aug 2018, In : Nature Reviews Microbiology. 16, 8, p. 508-518 11 p.

Research output: Contribution to journal › Review Article › Research › peer-review

14 Citations (Scopus)

Gut microbiota in Drosophila melanogaster interacts with Wolbachia but does not contribute to Wolbachia-mediated antiviral protection

Ye, H., Seleznev, A., Flores, H., Woolfit, M. & McGraw, B., 1 Feb 2017, In : Journal of Invertebrate Pathology. 143, p. 18-25 8 p.

Research output: Contribution to journal › Article › Research › peer-review

20 Citations (Scopus)

Novel Wolbachia-transinfected Aedes aegypti mosquitoes possess diverse fitness and vector competence phenotypes

Fraser, J. E., De Bruyne, J. T., Iturbe-Ormaetxe, I., Stepnell, J., Burns, R. L., Flores, H. A. & O’Neill, S. L., 1 Dec 2017, In : PLoS Pathogens. 13, 12, 19 p., e1006751.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

5 Citations (Scopus)

Adaptive evolution of genes involved in the regulation of germline stem cells in Drosophila melanogaster and D. simulans

Flores, H. A., DuMont, V. L. B., Fatoo, A., Hubbard, D., Hijji, M., Barbash, D. A. & Aquadro, C. F., 2015, In : G3: Genes, Genomes, Genetics. 5, 4, p. 583 - 592 10 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access