Projects per year
Personal profile
Biography
I am a Research Fellow in the School of Biological Sciences. My research focuses on the use of Wolbachia for the biocontrol of arboviruses in Aedes aegypti. Specifically, I am investigating the use and effectiveness of new Wolbachia strains, how Wolbachia evolves in the field post-release, and how nuclear and mitochondrial genomes interact to impact mosquito fitness and Wolbachia stability.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Genetics & Development, PhD, Cornell University
Award Date: 28 Jan 2013
Research area keywords
- Wolbachia
- Vector-borne disease
- Arbovirus
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Dissecting the implications of endosymbiont interactions for host fitness
Dowling, D. (Primary Chief Investigator (PCI)), Flores, H. (Chief Investigator (CI)) & Saleh, M. C. (Partner Investigator (PI))
1/01/25 → 31/12/27
Project: Research
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NHMRC Equipment Grant - Multichannel pipette
Flores, H. (Primary Chief Investigator (PCI))
1/11/24 → 31/12/25
Project: Research
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NHMRC Equipment Grant - Computer software mosquitoes tracking system
Flores, H. (Primary Chief Investigator (PCI)) & Dowling, D. (Chief Investigator (CI))
1/11/23 → 31/12/24
Project: Research
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Dissecting nuclear-mitochondria interactions in Aedes aegypti and their effects on Wolbachia biocontrol methods
Flores, H. (Primary Chief Investigator (PCI)), Dowling, D. (Chief Investigator (CI)), White, C. (Chief Investigator (CI)) & Simmons, C. (Associate Investigator (AI))
National Health and Medical Research Council (NHMRC) (Australia)
1/01/20 → 31/12/24
Project: Research
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Controlling vector-borne diseases by releasing modified mosquitoes
Flores, H. A. & O'Neill, S. L., 1 Aug 2018, In: Nature Reviews Microbiology. 16, 8, p. 508-518 11 p.Research output: Contribution to journal › Review Article › Research › peer-review
222 Citations (Scopus) -
wMel Wolbachia genome remains stable after 7 years in Australian Aedes aegypti field populations
Dainty, K. R., Hawkey, J., Judd, L. M., Pacidônio, E. C., Duyvestyn, J. M., Gonçalves, D. S., Lin, S. Y., O'Donnell, T. B., O'Neill, S. L., Simmons, C. P., Holt, K. E. & Flores, H. A., 1 Sept 2021, In: Microbial Genomics. 7, 9, 9 p., 000641.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile16 Citations (Scopus) -
Antiviral Wolbachia strains associate with Aedes aegypti endoplasmic reticulum membranes and induce lipid droplet formation to restrict dengue virus replication
Loterio, R. K., Monson, E. A., Templin, R., de Bruyne, J. T., Flores, H. A., Mackenzie, J. M., Ramm, G., Helbig, K. J., Simmons, C. P. & Fraser, J. E., 14 Feb 2024, In: mBio. 15, 2, 20 p., e0249523.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus) -
Enhancing the scalability of Wolbachia-based vector-borne disease management: time and temperature limits for storage and transport of Wolbachia-infected Aedes aegypti eggs for field releases
Allman, M. J. (Leading Author), Lin, Y.-H., Joubert, D. A., Addley-Cook, J., Mejía-Torres, M. C., Simmons, C. P., Flores, H. A. (Leading Author) & Fraser, J. E. (Leading Author), 2023, In: Parasites & Vectors. 16, 13 p., 108.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile5 Citations (Scopus) -
Genome evolution of dengue virus serotype 1 under selection by Wolbachia pipientis in Aedes aegypti mosquitoes
Thi Hue Kien, D., Edenborough, K., Da Silva Goncalves, D., Thuy Vi, T., Casagrande, E., Thi Le Duyen, H., Thi Long, V., Thi Dui, L., Thi Tuyet Nhu, V., Thi Giang, N., Thi Xuan Trang, H., Lee, E., Donovan-Banfield, I., Thi Thuy Van, H., Minh Nguyet, N., Thanh Phong, N., Van Vinh Chau, N., Wills, B., Yacoub, S. & Flores, H. & 1 others, , 2023, In: Virus Evolution. 9, 1, 35 p., vead016.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile12 Citations (Scopus)
Activities
- 1 Patents
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MONASH UNIVERSITY (Organisational unit)
Fraser, J. E. (Inventor), Taneja De Bruyne, J. T. (Inventor), Iturbe-Ormaeche, I. (Inventor), Flores, H. A. (Inventor) & O'Neill, S. (Inventor)
3 Jan 2019Activity: Industry, Government and Philanthropy Engagement and Partnerships › Patents › Patent