Gregory Challis

Research output

Research output per year 1998 2006 2007 2008 2009 2011 2012 2014 2016 2018 2019 2020 2021 2023

• 107 Article
• 16 Review Article
• 5 Editorial
• 4 Comment / Debate
• 6 More
  • 3 Short Survey
  • 2 Chapter (Book)
  • 1 Letter

Research output per year

Research output per year

Search results

• 2018

  Protein-protein interactions in trans-AT polyketide synthases

  Kosol, S., Jenner, M., Lewandowski, J. R. & Challis, G. L., 3 Oct 2018, In: Natural Product Reports. 35, 10, p. 1097-1109 13 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  21 Citations (Scopus)

• Rieske non-heme iron-dependent oxygenases catalyse diverse reactions in natural product biosynthesis

  Perry, C., De Los Santos, E. L. C., Alkhalaf, L. M. & Challis, G. L., 1 Jul 2018, In: Natural Product Reports. 35, 7, p. 622-632 11 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  52 Citations (Scopus)
• 2017

  Antibiotics from Gram-negative bacteria: A comprehensive overview and selected biosynthetic highlights

  Masschelein, J., Jenner, M. & Challis, G. L., 1 Jul 2017, In: Natural Product Reports. 34, 7, p. 712-783 72 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  70 Citations (Scopus)
• 2016

  Mechanistic insights into class B radical-S-adenosylmethionine methylases: ubiquitous tailoring enzymes in natural product biosynthesis

  Zhou, S., Alkhalaf, L. M., de los Santos, E. LC. & Challis, G. L., 1 Dec 2016, In: Current Opinion in Chemical Biology. 35, p. 73-79 7 p.

  Research output: Contribution to journal › Review Article › Other › peer-review
  30 Citations (Scopus)

• Structure, Chemical Synthesis, and Biosynthesis of Prodiginine Natural Products

  Hu, D. X., Withall, D. M., Challis, G. L. & Thomson, R. J., 27 Jul 2016, In: Chemical Reviews. 116, 14, p. 7818-7853 36 p.

  Research output: Contribution to journal › Review Article › Other › peer-review

  Open Access

  File
  112 Citations (Scopus)
• 2015

  Discovery of microbial natural products by activation of silent biosynthetic gene clusters

  Rutledge, P. J. & Challis, G. L., 29 Jun 2015, In: Nature Reviews Microbiology. 13, 8, p. 509-523 15 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  617 Citations (Scopus)
• 2014

  Exploitation of the Streptomyces coelicolor A3(2) genome sequence for discovery of new natural products and biosynthetic pathways

  Challis, G. L., Feb 2014, In: Journal of Industrial Microbiology and Biotechnology. 41, 2, p. 219-232 14 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  90 Citations (Scopus)

• Genome mining of Streptomyces ambofaciens

  Aigle, B., Lautru, S., Spiteller, D., Dickschat, J. S., Challis, G. L., Leblond, P. & Pernodet, J. L., Feb 2014, In: Journal of Industrial Microbiology and Biotechnology. 41, 2, p. 251-263 13 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  75 Citations (Scopus)
• 2013

  Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature

  Arnison, P. G., Bibb, M. J., Bierbaum, G., Bowers, A. A., Bugni, T. S., Bulaj, G., Camarero, J. A., Campopiano, D. J., Challis, G. L., Clardy, J., Cotter, P. D., Craik, D. J., Dawson, M., Dittmann, E., Donadio, S., Dorrestein, P. C., Entian, K. D., Fischbach, M. A., Garavelli, J. S., Göransson, U., & 45 othersGruber, C. W., Haft, D. H., Hemscheidt, T. K., Hertweck, C., Hill, C., Horswill, A. R., Jaspars, M., Kelly, W. L., Klinman, J. P., Kuipers, O. P., Link, A. J., Liu, W., Marahiel, M. A., Mitchell, D. A., Moll, G. N., Moore, B. S., Müller, R., Nair, S. K., Nes, I. F., Norris, G. E., Olivera, B. M., Onaka, H., Patchett, M. L., Piel, J., Reaney, M. J. T., Rebuffat, S., Ross, R. P., Sahl, H. G., Schmidt, E. W., Selsted, M. E., Severinov, K., Shen, B., Sivonen, K., Smith, L., Stein, T., Süssmuth, R. D., Tagg, J. R., Tang, G. L., Truman, A. W., Vederas, J. C., Walsh, C. T., Walton, J. D., Wenzel, S. C., Willey, J. M. & Van Der Donk, W. A., 2013, In: Natural Product Reports. 30, 1, p. 108-160 53 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  1416 Citations (Scopus)
• 2009

  Recent advances in siderophore biosynthesis

  Barry, S. M. & Challis, G. L., Apr 2009, In: Current Opinion in Chemical Biology. 13, 2, p. 205-215 11 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  113 Citations (Scopus)

• The long-overlooked enzymology of a nonribosomal peptide synthetase-independent pathway for virulence-conferring siderophore biosynthesis

  Oves-Costales, D., Kadi, N. F. & Challis, G. L., 2009, In: Chemical Communications. 43, p. 6530-6541 12 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  86 Citations (Scopus)
• 2008

  Genome mining for novel natural product discovery

  Challis, G. L., 8 May 2008, In: Journal of Medicinal Chemistry. 51, 9, p. 2618-2628 11 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  170 Citations (Scopus)
• 2007

  Non-linear enzymatic logic in natural product modular mega-synthases and -synthetases

  Haynes, S. W. & Challis, G. L., 1 Mar 2007, In: Current Opinion in Drug Discovery & Development. 10, 2, p. 203-218 16 p.

  Research output: Contribution to journal › Review Article › Research › peer-review

  31 Citations (Scopus)
• 2004

  Structural aspects of non-ribosomal peptide biosynthesis

  Challis, G. L. & Naismith, J. H., 1 Dec 2004, In: Current Opinion in Structural Biology. 14, 6, p. 748-756 9 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  91 Citations (Scopus)

• Substrate recognition by nonribosomal peptide synthetase multi-enzymes

  Lautru, S. & Challis, G. L., 1 Jan 2004, In: Microbiology. 150, 6, p. 1629-1636 8 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  85 Citations (Scopus)
• 1998

  Rate enhancement in the reduction of (2,3)-α- and (2,3)-β- methylenepenam β-sulfoxides

  Adlington, R. M., Baldwin, J. E. & Challis, G. L., 12 Nov 1998, In: Tetrahedron Letters. 39, 46, p. 8537-8540 4 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  8 Citations (Scopus)