Gregory Challis

Professor

Accepting PhD Students

19982019
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Personal profile

External positions

Professor, University of Warwick

15 Mar 2001 → …

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Research Output 1998 2019

An unusual Burkholderia gladioli double chain-initiating nonribosomal peptide synthetase assembles 'fungal' icosalide antibiotics

Jenner, M., Jian, X., Dashti, Y., Masschelein, J., Hobson, C., Roberts, D. M., Jones, C., Harris, S., Parkhill, J., Raja, H. A., Oberlies, N. H., Pearce, C. J., Mahenthiralingam, E. & Challis, G. L., 25 Apr 2019, In : Chemical Science. 10, 21, p. 5489-5494 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Binding of Distinct Substrate Conformations Enables Hydroxylation of Remote Sites in Thaxtomin D by Cytochrome P450 TxtC

Alkhalaf, L. M., Barry, S. M., Rea, D., Gallo, A., Griffiths, D., Lewandowski, J. R., Fulop, V. & Challis, G. L., 9 Jan 2019, In : Journal of the American Chemical Society. 141, 1, p. 216-222 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Genome mining identifies cepacin as a plant-protective metabolite of the biopesticidal bacterium Burkholderia ambifaria

Mullins, A. J., Murray, J. A. H., Bull, M. J., Jenner, M., Jones, C., Webster, G., Green, A. E., Neill, D. R., Connor, T. R., Parkhill, J., Challis, G. L. & Mahenthiralingam, E., 4 Mar 2019, In : Nature Microbiology. 4, p. 996-1005 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Pentamycin Biosynthesis in Philippine Streptomyces sp. S816: Cytochrome P450-Catalyzed Installation of the C-14 Hydroxyl Group

Zhou, S., Song, L., Masschelein, J., Sumang, F. A. M., Papa, I. A., Zulaybar, T. O., Custodio, A. B., Zabala, D., Alcantara, E. P., De Los Santos, E. L. C. & Challis, G. L., 16 May 2019, In : ACS Chemical Biology. 14, 6, p. 1305-1309 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Desferrioxamine biosynthesis: Diverse hydroxamate assembly by substrate-tolerant acyl transferase DesC

Ronan, J. L., Kadi, N., McMahon, S. A., Naismith, J. H., Alkhalaf, L. M. & Challis, G. L., 5 Jun 2018, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 373, 1748, 7 p., 20170068.

Research output: Contribution to journalArticleResearchpeer-review