Gregory Challis

Professor

Accepting PhD Students

19982019
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Personal profile

External positions

Professor, University of Warwick

15 Mar 2001 → …

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Research Output 1998 2019

1 Citation (Scopus)

A dual transacylation mechanism for polyketide synthase chain release in enacyloxin antibiotic biosynthesis

Masschelein, J., Sydor, P. K., Hobson, C., Howe, R., Jones, C., Roberts, D. M., Ling Yap, Z., Parkhill, J., Mahenthiralingam, E. & Challis, G. L., 1 Oct 2019, In : Nature Chemistry. 11, 10, p. 906-912 7 p.

Research output: Contribution to journalArticleResearchpeer-review

An unusual Burkholderia gladioli double chain-initiating nonribosomal peptide synthetase assembles 'fungal' icosalide antibiotics

Jenner, M., Jian, X., Dashti, Y., Masschelein, J., Hobson, C., Roberts, D. M., Jones, C., Harris, S., Parkhill, J., Raja, H. A., Oberlies, N. H., Pearce, C. J., Mahenthiralingam, E. & Challis, G. L., 25 Apr 2019, In : Chemical Science. 10, 21, p. 5489-5494 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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5 Citations (Scopus)

Binding of Distinct Substrate Conformations Enables Hydroxylation of Remote Sites in Thaxtomin D by Cytochrome P450 TxtC

Alkhalaf, L. M., Barry, S. M., Rea, D., Gallo, A., Griffiths, D., Lewandowski, J. R., Fulop, V. & Challis, G. L., 9 Jan 2019, In : Journal of the American Chemical Society. 141, 1, p. 216-222 7 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Genome mining identifies cepacin as a plant-protective metabolite of the biopesticidal bacterium Burkholderia ambifaria

Mullins, A. J., Murray, J. A. H., Bull, M. J., Jenner, M., Jones, C., Webster, G., Green, A. E., Neill, D. R., Connor, T. R., Parkhill, J., Challis, G. L. & Mahenthiralingam, E., 4 Mar 2019, In : Nature Microbiology. 4, p. 996-1005 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Pentamycin Biosynthesis in Philippine Streptomyces sp. S816: Cytochrome P450-Catalyzed Installation of the C-14 Hydroxyl Group

Zhou, S., Song, L., Masschelein, J., Sumang, F. A. M., Papa, I. A., Zulaybar, T. O., Custodio, A. B., Zabala, D., Alcantara, E. P., De Los Santos, E. L. C. & Challis, G. L., 16 May 2019, In : ACS Chemical Biology. 14, 6, p. 1305-1309 5 p.

Research output: Contribution to journalArticleResearchpeer-review