Research output per year

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Personal profile

Research interests

The Alfred Endoscopy Unit provides a wide range of services that include all basic diagnostic and therapeutic endoscopy through to advanced endoscopy with double-balloon enteroscopy, endoscopic ultrasound and advanced polypectomies. The Unit is active on several research fronts.

Understanding of colonic polypectomy

We have made significant contributions through prospective audit of our polypectomy practice, including giant flat polypectomy and more routine flat polypectomy, particularly in the handling of anticoagulants.

Assessment of novel approaches to bowel preparation prior to colonoscopy

This includes, including ultra-low residue 'White Diets' and different purgative preparations.

Risk of colonic polyps and bowel cancer in cystic fibrosis

We have identified a significantly increased risk of colorectal neoplasia inpatients with cystic fibrosis and are evaluating how to best screen for this complication.

Collaborative studies

We are collaborating with our Haematology colleagues in the assessment of patients with Graft Versus Host Disease after Bone Marrow Transplantation, and the role of PET scanning. We are assisting the Infectious Diseases Unit in the impact of novel treatment strategies on the immunology of the colon.

External positions

Epworth Health

Research area keywords

  • endoscopy
  • colonic polypectomy
  • colonoscopy
  • colonic polyps
  • bowel cancer

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Research Output

Augmentation with pre-emptive macrogol-based osmotic laxative does not significantly improve standard bowel preparation in unselected patients: A randomized trial

Mangira, D., Ket, S., Dwyer, J., Secomb, R., Reynolds, J. & Brown, G., 1 Oct 2019, In : JGH Open. 3, 5, p. 374-380 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Study design of endoscopic polypectomy on clopidogrel (EPOC): A randomised controlled trial

Ket, S., Metz, A., Moss, A., Ogra, R., Tam, W., Secomb, R., Reynolds, J., Gibson, P. R. & Brown, G., 1 Dec 2019, In : Contemporary Clinical Trials Communications. 16, 5 p., 100479.

Research output: Contribution to journalArticleOtherpeer-review

Open Access

Postpolypectomy prophylactic clip closure for the prevention of delayed postpolypectomy bleeding: A systematic review

Mangira, D., Ket, S. N., Majeed, A., Gibson, P. R. & Brown, G., 1 Jun 2018, In : JGH Open. 2, 3, p. 105-110 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
2 Citations (Scopus)

Adenoma recurrence after piecemeal colonic EMR is predictable: the Sydney EMR recurrence tool

Tate, D. J., Desomer, L., Klein, A., Brown, G., Hourigan, L. F., Lee, E. Y. T., Moss, A., Ormonde, D., Raftopoulos, S. C., Singh, R., Williams, S. J., Zanati, S. A., Byth, K. & Bourke, M. J., 1 Mar 2017, In : Gastrointestinal Endoscopy. 85, 3, p. 647-656.e6 10 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)