If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

The Alfred Endoscopy Unit provides a wide range of services that include all basic diagnostic and therapeutic endoscopy through to advanced endoscopy with double-balloon enteroscopy, endoscopic ultrasound and advanced polypectomies. The Unit is active on several research fronts.

Understanding of colonic polypectomy

We have made significant contributions through prospective audit of our polypectomy practice, including giant flat polypectomy and more routine flat polypectomy, particularly in the handling of anticoagulants.

Assessment of novel approaches to bowel preparation prior to colonoscopy

This includes, including ultra-low residue 'White Diets' and different purgative preparations.

Risk of colonic polyps and bowel cancer in cystic fibrosis

We have identified a significantly increased risk of colorectal neoplasia inpatients with cystic fibrosis and are evaluating how to best screen for this complication.

Collaborative studies

We are collaborating with our Haematology colleagues in the assessment of patients with Graft Versus Host Disease after Bone Marrow Transplantation, and the role of PET scanning. We are assisting the Infectious Diseases Unit in the impact of novel treatment strategies on the immunology of the colon.

Research area keywords

  • endoscopy
  • colonic polypectomy
  • colonoscopy
  • colonic polyps
  • bowel cancer

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2018 2020

Research Output 2009 2019

Augmentation with pre-emptive macrogol-based osmotic laxative does not significantly improve standard bowel preparation in unselected patients: A randomized trial

Mangira, D., Ket, S., Dwyer, J., Secomb, R., Reynolds, J. & Brown, G., 4 Apr 2019, (Accepted/In press) In : JGH Open. 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Adenoma recurrence after piecemeal colonic EMR is predictable: the Sydney EMR recurrence tool

Tate, D. J., Desomer, L., Klein, A., Brown, G., Hourigan, L. F., Lee, E. Y. T., Moss, A., Ormonde, D., Raftopoulos, S. C., Singh, R., Williams, S. J., Zanati, S. A., Byth, K. & Bourke, M. J., 1 Mar 2017, In : Gastrointestinal Endoscopy. 85, 3, p. 647-656.e6 10 p.

Research output: Contribution to journalArticleResearchpeer-review

A prospective comparison of cold snare polypectomy using traditional or dedicated cold snares for the resection of small sessile colorectal polyps

Dwyer, J. P., Tan, J. Y. C., Urquhart, P., Secomb, R., Bunn, C., Reynolds, J., La Nauze, R., Kemp, W., Roberts, S. & Brown, G., 27 Oct 2017, In : Endosc Int Open. 05, 11, p. E1062-E1068 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Endoscopic mucosal resection for large serrated lesions in comparison with adenomas: A prospective multicentre study of 2000 lesions

Pellise, M., Burgess, N. G., Tutticci, N., Hourigan, L. F., Zanati, S. A., Brown, G. J., Singh, R., Williams, S. J., Raftopoulos, S. C., Ormonde, D., Moss, A., Byth, K., P'Ng, H., Mahajan, H., Mcleod, D. & Bourke, M. J., 1 Apr 2017, In : Gut. 66, 4, p. 644-653 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies

Goel, G., King, T., Daveson, A. J., Andrews, J. M., Krishnarajah, J., Krause, R., Brown, G. J. E., Fogel, R., Barish, C. F., Epstein, R., Kinney, T. P., Miner, P. B., Tye-Din, J. A., Girardin, A., Taavela, J., Popp, A., Sidney, J., Mäki, M., Goldstein, K. E., Griffin, P. H. & 8 others, Wang, S., Dzuris, J. L., Williams, L. J., Sette, A., Xavier, R. J., Sollid, L. M., Jabri, B. & Anderson, R. P., 1 Jul 2017, In : The Lancet Gastroenterology and Hepatology. 2, 7, p. 479-493 15 p.

Research output: Contribution to journalArticleResearchpeer-review