20002020

Research output per year

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Personal profile

Biography

A/Prof Grant Drummond is a Senior Research Fellow of the National Health and Medical Research Council of Australia and co-leader (with Prof Chris Sobey) of the Vascular Biology and Immunopharmacology Group in the Cardiovascular Disease Program, Biomedicine Discovery Institute, and Department of Pharmacology, Monash University.



Since joining Monash in 2004, Grant Drummond has built up a reputation as a leading vascular pharmacologist and biologist in Australia and internationally, with expertise in mechanisms and consequences of elevated reactive oxygen species (ROS) production and oxidative stress in cardiovascular disease. His work has provided insights into the roles of NADPH oxidase-derived ROS as novel signalling molecules under normal physiological conditions, and as mediators of oxidative damage in vascular disease states such as atherosclerosis, hypertension and stroke. More recently, Grant's team have begun unraveling the role of inflammation and activation of immune system in the pathogenesis of hypertension, with particular interests in the roles of inflammasomes, macrophage polarization, and B cell activation.

Grant Drummond received his PhD from the Department of Pharmacology, University of Melbourne in 1998 and then completed 2 years of postdoctoral training at Emory University (Atlanta, USA) under Prof David Harrison. Grant returned to Australia in 2000 on a Peter Doherty Postdoctoral fellowship and spent 4 years working at the Howard Florey Institute with Prof Greg Dusting. He moved to Monash University in 2004 on a Monash Category I Fellowship and since this time has grown his research team such that it now comprises 7 postdocs, 2 research assistants, 7 postgraduate students and 4 Honours students. Grant is a Chief Investigator on 5 NHMRC Project Grants and his research has resulted in more than 100 publications. He is an Associate Editor of the British Journal of Pharmacology, Pharmacology and Therapeutics and Clinical and Experimental Pharmacology and Physiology and is on the editorial boards of 3 additional scientific journals. He is the current Chair of the Heart Foundation of Australia's Postdoctoral Fellowship Committee and has served as a member of Grant Review Panels for the NHMRC. He is also the current Honours convenor and an executive member of the Department of Pharmacology.

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Projects

Research Output

Deficiency of Prebiotic Fiber and Insufficient Signaling through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease

Kaye, D. M., Shihata, W. A., Jama, H. A., Tsyganov, K., Ziemann, M., Kiriazis, H., Horlock, D., Vijay, A., Giam, B., Vinh, A., Johnson, C., Fiedler, A., Donner, D., Snelson, M., Coughlan, M. T., Phillips, S., Du, X-J., El-Osta, A., Drummond, G., Lambert, G. W. & 4 others, Spector, T. D., Valdes, A. M., Mackay, C. R. & Marques, F. Z., 28 Apr 2020, In : Circulation. 141, 17, p. 1393-1403 11 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

New opportunities for targeting redox dysregulation in cardiovascular disease

Bubb, K. J., Drummond, G. R. & Figtree, G. A., Mar 2020, In : Cardiovascular Research. 116, 3, p. 532-544 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

Distinct Redox Signalling following Macrophage Activation Influences Profibrotic Activity

Lewis, C. V., Vinh, A., Diep, H., Samuel, C. S., Drummond, G. R. & Kemp-Harper, B. K., 11 Nov 2019, In : Journal of Immunology Research. 2019, 15 p., 1278301.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

IL-37 increases in patients after ischemic stroke and protects from inflammatory brain injury, motor impairment and lung infection in mice

Zhang, S. R., Nold, M. F., Tang, S. C., Bui, C. B., Nold, C. A., Arumugam, T. V., Drummond, G. R., Sobey, C. G. & Kim, H. A., 1 Dec 2019, In : Scientific Reports. 9, 1, 12 p., 6922.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)

Mild closed-head injury in conscious rats causes transient neurobehavioral and glial disturbances: A novel experimental model of concussion

Pham, L., Shultz, S. R., Kim, H. A., Brady, R., Wortman, R. C., Genders, S. G., Hale, M. W., O'Shea, R., Djouma, E., van den Buuse, M., Church, J. E., Christie, B. R., Drummond, G., Sobey, C. G. & McDonald, S., 15 Jul 2019, In : Journal of Neurotrauma. 36, 14, p. 2260-2271 12 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)