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Personal profile

Biography

A/Prof Grant Drummond is a Senior Research Fellow of the National Health and Medical Research Council of Australia and co-leader (with Prof Chris Sobey) of the Vascular Biology and Immunopharmacology Group in the Cardiovascular Disease Program, Biomedicine Discovery Institute, and Department of Pharmacology, Monash University.



Since joining Monash in 2004, Grant Drummond has built up a reputation as a leading vascular pharmacologist and biologist in Australia and internationally, with expertise in mechanisms and consequences of elevated reactive oxygen species (ROS) production and oxidative stress in cardiovascular disease. His work has provided insights into the roles of NADPH oxidase-derived ROS as novel signalling molecules under normal physiological conditions, and as mediators of oxidative damage in vascular disease states such as atherosclerosis, hypertension and stroke. More recently, Grant's team have begun unraveling the role of inflammation and activation of immune system in the pathogenesis of hypertension, with particular interests in the roles of inflammasomes, macrophage polarization, and B cell activation.

Grant Drummond received his PhD from the Department of Pharmacology, University of Melbourne in 1998 and then completed 2 years of postdoctoral training at Emory University (Atlanta, USA) under Prof David Harrison. Grant returned to Australia in 2000 on a Peter Doherty Postdoctoral fellowship and spent 4 years working at the Howard Florey Institute with Prof Greg Dusting. He moved to Monash University in 2004 on a Monash Category I Fellowship and since this time has grown his research team such that it now comprises 7 postdocs, 2 research assistants, 7 postgraduate students and 4 Honours students. Grant is a Chief Investigator on 5 NHMRC Project Grants and his research has resulted in more than 100 publications. He is an Associate Editor of the British Journal of Pharmacology, Pharmacology and Therapeutics and Clinical and Experimental Pharmacology and Physiology and is on the editorial boards of 3 additional scientific journals. He is the current Chair of the Heart Foundation of Australia's Postdoctoral Fellowship Committee and has served as a member of Grant Review Panels for the NHMRC. He is also the current Honours convenor and an executive member of the Department of Pharmacology.

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Projects 2005 2018

Research Output 2000 2018

Acute or Delayed Systemic Administration of Human Amnion Epithelial Cells Improves Outcomes in Experimental Stroke

Evans, M. A. , Lim, R. , Kim, H. A. , Chu, H. X. , Gardiner-Mann, C. V. , Taylor, K. W. E. , Chan, C. T. , Brait, V. H. , Lee, S. , Dinh, Q. N. , Vinh, A. , Phan, T. G. , Srikanth, V. K. , Ma, H. , Arumugam, T. V. , Fann, D. Y. , Poh, L. , Hunt, C. P. J. , Pouton, C. W. , Haynes, J. M. & 12 others Selemidis, S., Kwan, W., Teo, L., Bourne, J. A., Neumann, S., Young, S., Gowing, E. K., Drummond, G. R., Clarkson, A. N., Wallace, E. M., Sobey, C. G. & Broughton, B. R. S. 1 Mar 2018 In : Stroke. 49, 3, p. 700-709 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Amnion epithelial cells - A novel therapy for ischemic stroke?

Evans, M. A., Broughton, B. R. S., Drummond, G. R., Ma, H., Phan, T. G., Wallace, E. M., Lim, R. & Sobey, C. G. 1 Aug 2018 In : Neural Regeneration Research. 13, 8, p. 1346-1349 4 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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Evidence that NF-κB and MAPK Signaling Promotes NLRP Inflammasome Activation in Neurons Following Ischemic Stroke

Fann, D. Y. W., Lim, Y. A., Cheng, Y. L., Lok, K. Z., Chunduri, P., Baik, S. H., Drummond, G. R., Dheen, S. T., Sobey, C. G., Jo, D. G., Chen, C. L. H. & Arumugam, T. V. Feb 2018 In : Molecular Neurobiology. 55, 2, p. 1082-1096 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Proteomic Identification of Interferon-Induced Proteins with Tetratricopeptide Repeats as Markers of M1 Macrophage Polarization

Huang, C., Lewis, C., Borg, N. A., Canals, M., Diep, H., Drummond, G. R., Goode, R. J., Schittenhelm, R. B., Vinh, A., Zhu, M., Kemp-Harper, B., Kleifeld, O. & Stone, M. J. 6 Apr 2018 In : Journal of Proteome Research. 17, 4, p. 1485-1499 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Vitamin D3 Supplementation Reduces Subsequent Brain Injury and Inflammation Associated with Ischemic Stroke

Evans, M. A., Kim, H. A., Ling, Y. H., Uong, S., Vinh, A., De Silva, T. M., Arumugam, T. V., Clarkson, A. N., Zosky, G. R., Drummond, G. R., Broughton, B. R. S. & Sobey, C. G. 1 Mar 2018 In : NeuroMolecular Medicine. 20, 1, p. 147-159 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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