Graeme Lancaster

Mr

20042019

Research output per year

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2019

Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia

McKenzie, M. D., Ghisi, M., Oxley, E. P., Ngo, S., Cimmino, L., Esnault, C., Liu, R., Salmon, J. M., Bell, C. C., Ahmed, N., Erlichster, M., Witkowski, M. T., Liu, G. J., Chopin, M., Dakic, A., Simankowicz, E., Pomilio, G., Vu, T., Krsmanovic, P., Su, S. & 21 others, Tian, L., Baldwin, T. M., Zalcenstein, D. A., DiRago, L., Wang, S., Metcalf, D., Johnstone, R. W., Croker, B. A., Lancaster, G. I., Murphy, A. J., Naik, S. H., Nutt, S. L., Pospisil, V., Schroeder, T., Wall, M., Dawson, M. A., Wei, A. H., de Thé, H., Ritchie, M. E., Zuber, J. & Dickins, R. A., 1 Aug 2019, In : Cell Stem Cell. 25, 2, p. 258-272.e9 24 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)
2018

Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis

Dragoljevic, D., Kraakman, M. J., Nagareddy, P. R., Ngo, D., Shihata, W., Kammoun, H. L., Whillas, A., Lee, M. K. S., Al-Sharea, A., Pernes, G., Flynn, M. C., Lancaster, G. I., Febbraio, M. A., Chin-Dusting, J., Hanaoka, B. Y., Wicks, I. P. & Murphy, A. J., 14 Jun 2018, In : European Heart Journal. 39, 23, p. 2158-2167 11 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Evidence against a role for NLRP3-driven islet inflammation in db/db mice

Kammoun, H. L., Allen, T. L., Henstridge, D. C., Barre, S., Coll, R. C., Lancaster, G. I., Cron, L., Reibe, S., Chan, J. Y., Bensellam, M., Laybutt, D. R., Butler, M. S., Robertson, A. A. B., O'Neill, L. A., Cooper, M. A. & Febbraio, M. A., 1 Apr 2018, In : Molecular Metabolism. 10, p. 66-73 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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10 Citations (Scopus)

Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism

Lancaster, G. I., Langley, K. G., Berglund, N. A., Kammoun, H. L., Reibe, S., Estevez, E., Weir, J., Mellett, N. A., Pernes, G., Conway, J. R. W., Lee, M. K. S., Timpson, P., Murphy, A. J., Masters, S. L., Gerondakis, S., Bartonicek, N., Kaczorowski, D. C., Dinger, M. E., Meikle, P. J., Bond, P. J. & 1 others, Febbraio, M. A., 1 May 2018, In : Cell Metabolism. 27, 5, p. 1096-1110 16 p.

Research output: Contribution to journalArticleResearchpeer-review

66 Citations (Scopus)

Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome

Kraakman, M. J., Kammoun, H. L., Dragoljevic, D., Al-Sharea, A., Lee, M. K. S., Flynn, M. C., Stolz, C. J., Guirguis, A. A., Lancaster, G. I., Chin-Dusting, J., Curtis, D. J. & Murphy, A. J., 23 Mar 2018, In : Haematologica: the hematology journal. 103, 4, p. 597-606 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)
2016

Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism

Chaurasia, B., Kaddai, V. A., Lancaster, G. I., Henstridge, D. C., Sriram, S., Galam, D. L. A., Gopalan, V., Prakash, K. N. B., Velan, S. S., Bulchand, S., Tsong, T. J., Wang, M., Siddique, M. M., Yuguang, G., Sigmundsson, K., Mellet, N. A., Weir, J. M., Meikle, P. J., Bin M. Yassin, M. S., Shabbir, A. & 5 others, Shayman, J. A., Hirabayashi, Y., Shiow, S-A. T. E., Sugii, S. & Summers, S. A., 13 Dec 2016, In : Cell Metabolism. 24, 6, p. 820-834 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
57 Citations (Scopus)

PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications

Lancaster, G. I., Kammoun, H. L., Kraakman, M. J., Kowalski, G. M., Bruce, C. R. & Febbraio, M. A., 3 Feb 2016, In : Nature Communications. 7, 10 p., 10626.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
17 Citations (Scopus)

The roles of c-Jun NH2-terminal kinases (JNKs) in obesity and insulin resistance

Pal, M., Febbraio, M. A. & Lancaster, G. I., 15 Jan 2016, In : The Journal of Physiology. 594, 2, p. 267-279 13 p.

Research output: Contribution to journalArticleOtherpeer-review

46 Citations (Scopus)
2015

Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance

Kraakman, M. J., Kammoun, H. L., Allen, T. L., Deswaerte, V., Henstridge, D. C., Estevez, E., Matthews, V. B., Neill, B. A., White, D. A., Murphy, A. J., Peijs, L., Yang, C., Risis, S., Bruce, C. R., Du, X-J., Bobik, A., Lee-Young, R. S., Kingwell, B. A., Vasanthakumar, A., Shi, W. & 4 others, Kallies, A., Lancaster, G. I., Rose-John, S. & Febbraio, M. A., 3 Mar 2015, In : Cell Metabolism. 21, 3, p. 403-416 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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99 Citations (Scopus)
2012

Contraction-induced interleukin-6 gene transcription in skeletal muscle is regulated by c-Jun terminal kinase/activator protein-1

Whitham, M., Chan, M. H. S., Pal, M., Matthews, V. B., Prelovsek, O., Lunke, S., El-Osta, A., Broenneke, H., Alber, J., Bruning, J. C., Wunderlich, F. T., Lancaster, G. I. & Febbraio, M. A., 30 Mar 2012, In : Journal of Biological Chemistry. 287, 14, p. 10771-10779 9 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin

Winbanks, C. E., Weeks, K. L., Thomson, R. E., Sepulveda, P. V., Beyer, C., Qian, H., Chen, J. L., Allen, J. M., Lancaster, G. I., Febbraio, M. A., Harrison, C. A., McMullen, J. R., Chamberlain, J. S. & Gregorevic, P., 28 Jun 2012, In : Journal of Cell Biology. 197, 7, p. 997-1008 12 p.

Research output: Contribution to journalArticleResearchpeer-review

90 Citations (Scopus)

IκB kinase β (IKKβ) does not mediate feedback inhibition of the insulin signalling cascade

Lancaster, G. I., Skiba, B., Yang, C., Nicholls, H. T., Langley, K. G., Chan, M. H. S., Bruce, C. R., Rewcastle, G. W., Shepherd, P. R., Karin, M. & Febbraio, M. A., 15 Mar 2012, In : Biochemical Journal. 442, 3, p. 723-732 10 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)
2008

Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes

Soro-Paavonen, A., Watson, A. M. D., Li, J., Paavonen, K., Koitka, A., Calkin, A. C., Barit, D., Coughlan, M. T., Drew, B. G., Lancaster, G. I., Thomas, M., Forbes, J. M., Nawroth, P. P., Bierhaus, A., Cooper, M. E. & Jandeleit-Dahm, K. A., 1 Sep 2008, In : Diabetes. 57, 9, p. 2461-2469 9 p.

Research output: Contribution to journalArticleResearchpeer-review

293 Citations (Scopus)
2007

Effect of high-frequency resistance exercise on adaptive responses in skeletal muscle

Coffey, V. G., Reeder, D. W., Lancaster, G. I., Yeo, W. K., Febbraio, M. A., Yaspelkis, B. B. & Hawley, J. A., 1 Dec 2007, In : Medicine and Science in Sports and Exercise. 39, 12, p. 2135-2144 10 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)
2005

Exosome-dependent trafficking of HSP70: A novel secretory pathway for cellular stress proteins

Lancaster, G. I. & Febbraio, M. A., 17 Jun 2005, In : Journal of Biological Chemistry. 280, 24, p. 23349-23355 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
380 Citations (Scopus)
2004

Exercise induces the release of heat shock protein 72 from the human brain in vivo

Lancaster, G. I., Møller, K., Nielsen, B., Secher, N. H., Febbraio, M. A. & Nybo, L., 1 Sep 2004, In : Cell Stress and Chaperones. 9, 3, p. 276-280 5 p.

Research output: Contribution to journalArticleResearchpeer-review

84 Citations (Scopus)