Graeme Lancaster

Mr

20042019

Research output per year

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Research Output

Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism

Chaurasia, B., Kaddai, V. A., Lancaster, G. I., Henstridge, D. C., Sriram, S., Galam, D. L. A., Gopalan, V., Prakash, K. N. B., Velan, S. S., Bulchand, S., Tsong, T. J., Wang, M., Siddique, M. M., Yuguang, G., Sigmundsson, K., Mellet, N. A., Weir, J. M., Meikle, P. J., Bin M. Yassin, M. S., Shabbir, A. & 5 others, Shayman, J. A., Hirabayashi, Y., Shiow, S-A. T. E., Sugii, S. & Summers, S. A., 13 Dec 2016, In : Cell Metabolism. 24, 6, p. 820-834 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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58 Citations (Scopus)

Adiponectin sphings into action

Lancaster, G. I. & Febbraio, M. A., Jan 2011, In : Nature Medicine. 17, 1, p. 37-38 2 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

11 Citations (Scopus)

Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance

Kraakman, M. J., Kammoun, H. L., Allen, T. L., Deswaerte, V., Henstridge, D. C., Estevez, E., Matthews, V. B., Neill, B. A., White, D. A., Murphy, A. J., Peijs, L., Yang, C., Risis, S., Bruce, C. R., Du, X-J., Bobik, A., Lee-Young, R. S., Kingwell, B. A., Vasanthakumar, A., Shi, W. & 4 others, Kallies, A., Lancaster, G. I., Rose-John, S. & Febbraio, M. A., 3 Mar 2015, In : Cell Metabolism. 21, 3, p. 403-416 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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104 Citations (Scopus)

Contraction-induced interleukin-6 gene transcription in skeletal muscle is regulated by c-Jun terminal kinase/activator protein-1

Whitham, M., Chan, M. H. S., Pal, M., Matthews, V. B., Prelovsek, O., Lunke, S., El-Osta, A., Broenneke, H., Alber, J., Bruning, J. C., Wunderlich, F. T., Lancaster, G. I. & Febbraio, M. A., 30 Mar 2012, In : Journal of Biological Chemistry. 287, 14, p. 10771-10779 9 p.

Research output: Contribution to journalArticleResearchpeer-review

52 Citations (Scopus)

Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis

Dragoljevic, D., Kraakman, M. J., Nagareddy, P. R., Ngo, D., Shihata, W., Kammoun, H. L., Whillas, A., Lee, M. K. S., Al-Sharea, A., Pernes, G., Flynn, M. C., Lancaster, G. I., Febbraio, M. A., Chin-Dusting, J., Hanaoka, B. Y., Wicks, I. P. & Murphy, A. J., 14 Jun 2018, In : European Heart Journal. 39, 23, p. 2158-2167 11 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Effect of high-frequency resistance exercise on adaptive responses in skeletal muscle

Coffey, V. G., Reeder, D. W., Lancaster, G. I., Yeo, W. K., Febbraio, M. A., Yaspelkis, B. B. & Hawley, J. A., 1 Dec 2007, In : Medicine and Science in Sports and Exercise. 39, 12, p. 2135-2144 10 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Erratum: IκB kinase β (IKKβ) does not mediate feedback inhibition of the insulinsignalling cascade (Biochemical Journal (2012) 442 (723-732))

Lancaster, G. I., Skiba, B., Yang, C., Nicholls, H. T., Langley, K. G., Chan, M. H. S., Bruce, C. R., Rewcastle, G. W., Shepherd, P. R., Karin, M. & Febbraio, M. A., 15 May 2013, In : Biochemical Journal. 452, 1, p. 171 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Evidence against a role for NLRP3-driven islet inflammation in db/db mice

Kammoun, H. L., Allen, T. L., Henstridge, D. C., Barre, S., Coll, R. C., Lancaster, G. I., Cron, L., Reibe, S., Chan, J. Y., Bensellam, M., Laybutt, D. R., Butler, M. S., Robertson, A. A. B., O'Neill, L. A., Cooper, M. A. & Febbraio, M. A., 1 Apr 2018, In : Molecular Metabolism. 10, p. 66-73 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
10 Citations (Scopus)

Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism

Lancaster, G. I., Langley, K. G., Berglund, N. A., Kammoun, H. L., Reibe, S., Estevez, E., Weir, J., Mellett, N. A., Pernes, G., Conway, J. R. W., Lee, M. K. S., Timpson, P., Murphy, A. J., Masters, S. L., Gerondakis, S., Bartonicek, N., Kaczorowski, D. C., Dinger, M. E., Meikle, P. J., Bond, P. J. & 1 others, Febbraio, M. A., 1 May 2018, In : Cell Metabolism. 27, 5, p. 1096-1110 16 p.

Research output: Contribution to journalArticleResearchpeer-review

74 Citations (Scopus)

Exercise and the immune system: Implications for elite athletes and the general population

Lancaster, G. I. & Febbraio, M. A., 1 Feb 2016, In : Immunology and Cell Biology. 94, 2, p. 115-116 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

3 Citations (Scopus)

Exercise induces the release of heat shock protein 72 from the human brain in vivo

Lancaster, G. I., Møller, K., Nielsen, B., Secher, N. H., Febbraio, M. A. & Nybo, L., 1 Sep 2004, In : Cell Stress and Chaperones. 9, 3, p. 276-280 5 p.

Research output: Contribution to journalArticleResearchpeer-review

84 Citations (Scopus)

Exosome-dependent trafficking of HSP70: A novel secretory pathway for cellular stress proteins

Lancaster, G. I. & Febbraio, M. A., 17 Jun 2005, In : Journal of Biological Chemistry. 280, 24, p. 23349-23355 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
389 Citations (Scopus)

Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin

Winbanks, C. E., Weeks, K. L., Thomson, R. E., Sepulveda, P. V., Beyer, C., Qian, H., Chen, J. L., Allen, J. M., Lancaster, G. I., Febbraio, M. A., Harrison, C. A., McMullen, J. R., Chamberlain, J. S. & Gregorevic, P., 28 Jun 2012, In : Journal of Cell Biology. 197, 7, p. 997-1008 12 p.

Research output: Contribution to journalArticleResearchpeer-review

91 Citations (Scopus)

Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia

McKenzie, M. D., Ghisi, M., Oxley, E. P., Ngo, S., Cimmino, L., Esnault, C., Liu, R., Salmon, J. M., Bell, C. C., Ahmed, N., Erlichster, M., Witkowski, M. T., Liu, G. J., Chopin, M., Dakic, A., Simankowicz, E., Pomilio, G., Vu, T., Krsmanovic, P., Su, S. & 21 others, Tian, L., Baldwin, T. M., Zalcenstein, D. A., DiRago, L., Wang, S., Metcalf, D., Johnstone, R. W., Croker, B. A., Lancaster, G. I., Murphy, A. J., Naik, S. H., Nutt, S. L., Pospisil, V., Schroeder, T., Wall, M., Dawson, M. A., Wei, A. H., de Thé, H., Ritchie, M. E., Zuber, J. & Dickins, R. A., 1 Aug 2019, In : Cell Stem Cell. 25, 2, p. 258-272.e9 24 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

IκB kinase β (IKKβ) does not mediate feedback inhibition of the insulin signalling cascade

Lancaster, G. I., Skiba, B., Yang, C., Nicholls, H. T., Langley, K. G., Chan, M. H. S., Bruce, C. R., Rewcastle, G. W., Shepherd, P. R., Karin, M. & Febbraio, M. A., 15 Mar 2012, In : Biochemical Journal. 442, 3, p. 723-732 10 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome

Kraakman, M. J., Kammoun, H. L., Dragoljevic, D., Al-Sharea, A., Lee, M. K. S., Flynn, M. C., Stolz, C. J., Guirguis, A. A., Lancaster, G. I., Chin-Dusting, J., Curtis, D. J. & Murphy, A. J., 23 Mar 2018, In : Haematologica: the hematology journal. 103, 4, p. 597-606 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

Mechanisms of stress-induced cellular HSP72 release: Implications for exercise-induced increases in extracellular HSP72

Lancaster, G. I. & Febbraio, M. A., 1 Dec 2005, In : Exercise Immunology Review. 11, p. 46-52 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

57 Citations (Scopus)

PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications

Lancaster, G. I., Kammoun, H. L., Kraakman, M. J., Kowalski, G. M., Bruce, C. R. & Febbraio, M. A., 3 Feb 2016, In : Nature Communications. 7, 10 p., 10626.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
17 Citations (Scopus)

Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes

Soro-Paavonen, A., Watson, A. M. D., Li, J., Paavonen, K., Koitka, A., Calkin, A. C., Barit, D., Coughlan, M. T., Drew, B. G., Lancaster, G. I., Thomas, M., Forbes, J. M., Nawroth, P. P., Bierhaus, A., Cooper, M. E. & Jandeleit-Dahm, K. A., 1 Sep 2008, In : Diabetes. 57, 9, p. 2461-2469 9 p.

Research output: Contribution to journalArticleResearchpeer-review

295 Citations (Scopus)

Role of inflammation in the pathogenesis of insulin resistance

Lancaster, G. I., Hevener, A. & Febbraio, M. A., 1 Jan 2008, Diabetes: Translating Research into Practice. CRC Press, p. 57-74 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Skeletal muscle: Not simply an organ for locomotion and energy storage

Lancaster, G. I. & Febbraio, M. A., 12 Feb 2009, In : Journal of Physiology. 587, 3, p. 509-510 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access
9 Citations (Scopus)

The immunomodulating role of exercise in metabolic disease

Lancaster, G. I. & Febbraio, M. A., Jun 2014, In : Trends in Immunology. 35, 6, p. 262-269 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

74 Citations (Scopus)

The roles of c-Jun NH2-terminal kinases (JNKs) in obesity and insulin resistance

Pal, M., Febbraio, M. A. & Lancaster, G. I., 15 Jan 2016, In : The Journal of Physiology. 594, 2, p. 267-279 13 p.

Research output: Contribution to journalArticleOtherpeer-review

47 Citations (Scopus)