20072021

Research activity per year

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Personal profile

Biography

Dr Gonzalo del Monte-Nieto received his PhD in 2011 from the Autonoma University of Madrid (Spain), training in molecular and developmental biology supervised by Prof José Luis de la Pompa and on 3D image analysis by Prof Antoon Moorman (the Netherlands). During this time, he developed a protocol for monitoring the Notch1 activity during development that not only helped to describe for the first time the cells and tissues where the Notch pathway is active in the developing embryo and adult tissues, but also to decode complex developmental processes such as cardiac ventricular trabeculation, valvulogenesis and somitogenesis. Furthermore, his PhD work determined for the first time the role of the Notch pathway during epicardium and coronary artery formation. In 2011, he joined Prof Richard Harvey laboratory at Victor Chang Cardiac Research Institute (Sydney). His research focus lays in the study of the molecular mechanisms and developmental processes orchestrating heart development and the translation of this knowledge into congenital heart disease and cardiac regeneration. On this regard, his recent research has described a new revolutionary model for cardiac chamber development with special focus in trabeculation by integrating the cellular and extracellular components of the heart with important implications for better understanding congenital and adult heart disease.

Research interests

  • To study the molecular mechanisms and developmental processes controlling heart development.
  • To understand the molecular and cellular etiology of Congenital Heart Disease.
  • To study ECM composition/patterning during heart development, adulthood and disease/injury models.
  • To develop computational models for the different developmental processes in the heart.
  • To apply the knowledge generated from developmental biology to improve heart regeneration, organ-on-a-chip technologies and tissue engineering.

Education/Academic qualification

Molecular Biology, PhD Degree, Universidad Autonoma de Madrid (Autonomous University of Madrid)

Award Date: 29 Apr 2011

Molecular Biology, Masters Degree, Universidad Autonoma de Madrid (Autonomous University of Madrid)

20052007

Biology, Bachelor Degree, Universidad Autonoma de Madrid (Autonomous University of Madrid)

20002005

Molecular Biology, PhD

External positions

Con-joint Senior Lecturer , University of New South Wales

20152018

Senior Postdoctoral Scientist, Victor Chang Cardiac Research Institute (VCCRI)

20152018

Postdoctoral Scientist, Victor Chang Cardiac Research Institute (VCCRI)

20112015

PhD Student, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) (Spanish National Center for Cardiovascular Research)

20092011

Short-Stay PhD student, Amsterdam Universitair Medische Centra (Amsterdam UMC)

2008

PhD Student, Centro Nacional de Biotecnologia/CSIC, Madrid, Spain

20072009

Masters Student, Centro Nacional de Biotecnologia/CSIC, Madrid, Spain

20062007

Undergraduate training student, Centro Nacional de Biotecnologia/CSIC, Madrid, Spain

20032006

Research area keywords

  • Developmental Biology
  • Developmental Origins of Health and Disease
  • Congenital Disease
  • heart disease
  • Regenerative Medicine
  • Organ on chip
  • Genetic Models

Network

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