20012020

Research output per year

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Personal profile

Biography

Career Summary: Prof Glen Westall is a Consultant Chest Physician, and Head of the Paediatric Lung Transplant Program at the Alfred Hospital, Melbourne. He trained at King’s College London, and completed his respiratory training at the Alfred Hospital, Melbourne and Royal Brompton Hospital, London. Prof Westall successfully applied to the Australian Health Ministers’ Advisory Council (AHMAC) to have paediatric lung transplantation recognized as requiring National Funding Centre (NFC) status in Australia and for the service to be established at the Alfred Hospital. In addition, Prof Westall is a lead Consultant in Victoria’s largest dedicated Lung Fibrosis service that operates within the Department of Allergy, Immunology and Respiratory Medicine at the Alfred Hospital. Prof Westall has established and is principal investigator of open-access national tissue bank consisting of explanted lung tissue collected at the time of lung transplantation from patients with severe ILD. Prof Westall is an integral member of an Australian-wide network of ILD researchers that aims to establish lung cell lines derived from patients with ILD.

Research Support: Prof Westall oversees the research portfolio of the Alfred’s lung transplant service. As an academic clinician, he has established a number of translational projects with industry partners that have taken discoveries in basic science to the clinical interface. In particular he has established biorepositories that collect and store both normal lung tissue (from deceased patients whose families consent to release lung tissue for research) and fibrotic lungs. In addition, Prof Westall has established a biorepository of blood and BAL samples that are collected longitudinally on all patients undergoing lung transplantation. These transplant samples provide the basis of a research model that has resulted in a number of research collaborations whereby the immune response to infection (ever-present in the immunosuppressed host) and transplantation can be studied. Prof Westall has developed a wider interest into how activation of the innate immune system early post-lung transplant influences clinical outcomes. Establishing a research platform in pulmonary xenotransplantation has resulted in the award of an internationally competitive Career Development Award. Clinically, Prof Westall is a principal and co-investigator on numerous studies in viral immunity, lung fibrosis, and lung transplantation. Prof Westall is the principal investigator of a number of other transplant studies that have generated over $1 million in financial support over the past 5 years. Additionally, Prof Westall is a co-investigator in a large number of studies that have generated over $2 million research funding to The Alfred and Monash University.

 

External positions

Lung Transplant Physician, Alfred Health

1 Jun 20071 Dec 2020

Research area keywords

  • lung transplant recipients
  • Transplantation biology
  • Lung Fibrosis

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Projects

Research Output

A donor PaO2/FiO2 < 300 mm Hg does not determine graft function or survival after lung transplantation

Whitford, H., Kure, C. E., Henriksen, A., Hobson, J., Snell, G. I., Levvey, B. J., Marasco, S. F., Gooi, J. H., Zimmet, A., Negri, J., Pick, A., Buckland, M., Williams, T., Westall, G., Paraskeva, M. A., Martin, C. & McGiffin, D. C., 1 Jan 2020, In : Journal of Heart and Lung Transplantation. 39, 1, p. 53-61 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
1 Citation (Scopus)

A Potential Role for NKG2C+ γδ T Cells as a Cellular Therapy in Combating Post-Lung Transplant Cytomegalovirus Infection

Stankovic, S., Davey, M. S., Shaw, E. M., Cristiano, Y., Snell, G. I., Westall, G. P., Brooks, A. G. & Sullivan, L. C., Apr 2020, In : Journal of Heart and Lung Transplantation. 39, 4, p. S82-S82 1 p.

Research output: Contribution to journalMeeting AbstractOtherpeer-review

Cost-effectiveness of transplanting lungs and kidneys from donors with potential hepatitis C exposure or infection

Scott, N., Snell, G., Westall, G., Pilcher, D., Raggatt, M., Walker, R. G., Hellard, M., Peleg, A. Y. & Doyle, J., 29 Jan 2020, In : Scientific Reports. 10, 1, 11 p., 1459.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Donor Lung Referrals for Lung Transplantation: A ‘Behind The Scenes’ View

Snell, G. I., Levvey, B. J., Henriksen, A., Whitford, H. M., Levin, K., Paraskeva, M., Kotecha, S., Williams, T., Westall, G. P. & McGiffin, D., May 2020, In : Heart Lung and Circulation. 29, 5, p. 793-799 7 p.

Research output: Contribution to journalArticleResearchpeer-review

A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1

Le Nours, J., Gherardin, N. A., Ramarathinam, S. H., Awad, W., Wiede, F., Gully, B. S., Khandokar, Y., Praveena, T., Wubben, J. M., Sandow, J. J., Webb, A. I., von Borstel, A., Rice, M. T., Redmond, S. J., Seneviratna, R., Sandoval-Romero, M. L., Li, S., Souter, M. N. T., Eckle, S. B. G., Corbett, A. J. & 15 others, Reid, H. H., Liu, L., Fairlie, D. P., Giles, E. M., Westall, G. P., Tothill, R. W., Davey, M. S., Berry, R., Tiganis, T., McCluskey, J., Pellicci, D. G., Purcell, A. W., Uldrich, A. P., Godfrey, D. I. & Rossjohn, J., 20 Dec 2019, In : Science. 366, 6472, p. 1522-1527 6 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)