Projects per year
Personal profile
Biography
Career Summary: Prof Glen Westall is a Consultant Chest Physician, and Head of the Paediatric Lung Transplant Program at the Alfred Hospital, Melbourne. He trained at King’s College London, and completed his respiratory training at the Alfred Hospital, Melbourne and Royal Brompton Hospital, London. Prof Westall successfully applied to the Australian Health Ministers’ Advisory Council (AHMAC) to have paediatric lung transplantation recognized as requiring National Funding Centre (NFC) status in Australia and for the service to be established at the Alfred Hospital. In addition, Prof Westall is a lead Consultant in Victoria’s largest dedicated Lung Fibrosis service that operates within the Department of Allergy, Immunology and Respiratory Medicine at the Alfred Hospital. Prof Westall has established and is principal investigator of open-access national tissue bank consisting of explanted lung tissue collected at the time of lung transplantation from patients with severe ILD. Prof Westall is an integral member of an Australian-wide network of ILD researchers that aims to establish lung cell lines derived from patients with ILD.
Research Support: Prof Westall oversees the research portfolio of the Alfred’s lung transplant service. As an academic clinician, he has established a number of translational projects with industry partners that have taken discoveries in basic science to the clinical interface. In particular he has established biorepositories that collect and store both normal lung tissue (from deceased patients whose families consent to release lung tissue for research) and fibrotic lungs. In addition, Prof Westall has established a biorepository of blood and BAL samples that are collected longitudinally on all patients undergoing lung transplantation. These transplant samples provide the basis of a research model that has resulted in a number of research collaborations whereby the immune response to infection (ever-present in the immunosuppressed host) and transplantation can be studied. Prof Westall has developed a wider interest into how activation of the innate immune system early post-lung transplant influences clinical outcomes. Establishing a research platform in pulmonary xenotransplantation has resulted in the award of an internationally competitive Career Development Award. Clinically, Prof Westall is a principal and co-investigator on numerous studies in viral immunity, lung fibrosis, and lung transplantation. Prof Westall is the principal investigator of a number of other transplant studies that have generated over $1 million in financial support over the past 5 years. Additionally, Prof Westall is a co-investigator in a large number of studies that have generated over $2 million research funding to The Alfred and Monash University.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Lung Transplant Physician, Alfred Hospital
1 Jun 2007 → 1 Dec 2020
Research area keywords
- lung transplant recipients
- Transplantation biology
- Lung Fibrosis
Collaborations and top research areas from the last five years
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Establishing a novel human model for anti-fibrotic drug screening in silicosis
Bourke, J., Royce, S., Leong, T., Corrie, S., Harris, J., Sim, C. T. K., Hoy, R., Westall, G., Bardin, P. & Chen, Y.
iCare NSW (Insurance and Care NSW) (New South Wales)
1/01/23 → 27/03/26
Project: Research
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CRE for Interstitial Lung Disease - towards Individualised Care
Corte, T. J., Holland, A., Chambers, D. C., Hansbro, P. M., Dickinson, J. L., Palmer, A. J., Moodley, Y. P., Powell, J. E., Knibbs, L. D., Smallwood, N., Brooke, M., Glaspole, I., Goh, N., Westall, G., Reynolds, P. N., Hancock, K., Troy, L. K., Mackintosh, J. A., Price, D. P. T. & Dowling, J.
National Health and Medical Research Council (NHMRC) (Australia)
1/11/22 → 31/10/27
Project: Research
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PROPHECY: Profiling immune RespOnses in Paediatric and High risk populations to SARS-CoV-2
McMahon, J., van Zelm, M., Khoury, G., Drummer, H., Mulley, W., Holland, A., Woolley, I., Ojaimi, S., Rogers, B., Hoi, A., Trauer, J., Sparrow, M., Licciardi, P. V., Giles, E., Curtis, D., Crawford, N., Leech, M., Westall, G., O'Hehir, R., Jones, A., Morand, E., Bosco, J. J. & Turner, S.
Monash University, Alfred Health, Monash Health, Murdoch Children's Research Institute, Burnet Institute (Australia), Spleen Australia, National Association of People with HIV Australia (NAPWHA) Incorporated, Musculoskeletal Australia , Safer Care Victoria (SCV)
1/06/22 → 30/05/26
Project: Research
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Silicosis - Harnessing new ideas to conquer the re-emergence of an ancient lung disease - The SHIELD Study
Chambers, D., Westall, G., Goh, N., Bozinovski, S. & Corte, T. J.
Department of Health and Aged Care (Australia)
1/04/22 → 31/05/25
Project: Research
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NHMRC 2003 S/Ship - G Westall
National Health and Medical Research Council (NHMRC) (Australia)
3/02/03 → …
Project: Research
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Chronic lung allograft dysfunction is associated with an increased number of non-HLA antibodies
Xu, Q., Elrefaei, M., Taupin, J. L., Hitchman, K. M. K., Hiho, S., Gareau, A. J., Iasella, C. J., Marrari, M., Belousova, N., Bettinotti, M., Narula, T., Alvarez, F., Sanchez, P. G., Levvey, B., Westall, G., Snell, G., Levine, D. J., Zeevi, A. & Roux, A., Apr 2024, In: The Journal of Heart and Lung Transplantation. 43, 4, p. 663-672 10 p.Research output: Contribution to journal › Article › Research › peer-review
5 Citations (Scopus) -
Utility of the Stanford Integrated Psychosocial Assessment for Transplant in predicting outcomes before and after lung transplantation
Westall, G. P., Barnes, H., Levin, K., Gaffney, N., Harris, J., Martinez, O., Emsley, C., Fuller, L., Levvey, B., Snell, G. I. & Winton-Brown, T., Apr 2024, In: The Journal of Heart and Lung Transplantation. 43, 4, p. 571-579 9 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Cytomegalovirus Immunity Assays Predict Viremia but not Replication Within the Lung Allograft
Li, J., Gardiner, B. J., Stankovic, S., Oates, C. V. L., Cristiano, Y., Levvey, B. J., Brooks, A. G., Snell, G. I., Westall, G. P. & Sullivan, L. C., 9 Jun 2023, In: Transplantation Direct. 9, 7, 8 p., e1501.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Self-reported engagement in everyday activities following bilateral lung transplantation in paediatric cystic fibrosis: A single centre study
Marshall, J-M., Schneider, E., O’Mahony, S., Lannin, N., Westall, G. P. & Bhopti, A., 20 Dec 2023, In: BMJ Paediatrics Open. 7, 1, 8 p., e002251.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Coagulation factor-XII induces interleukin-6 by primary lung fibroblasts: a role in idiopathic pulmonary fibrosis?
Jaffar, J., McMillan, L., Wilson, N., Panousis, C., Hardy, C., Cho, H-J., Symons, K., Glaspole, I., Westall, G. & Wong, M., Feb 2022, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 322, 2, p. L258-L272 15 p.Research output: Contribution to journal › Article › Research › peer-review
4 Citations (Scopus)