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Personal profile

Research interests

I am a post-doc currently working in Nicola's Harris' lab at Monash University. 

 

My key interest resides in the function of eosinophils in both helminth infection and under homeostatic conditions. Primarily, I am researching the role of eosinophils in facilitating both tissue repair and immune cell regulation under these conditions. Eosinophillia presents itself as a key feature during helminth infection in both humans and rodents. In recent years, it is becoming more apparent that eosinophils may play a more complex role during infection, other than supporting larval killing and subsequent worm clearance (where in some instances, they may be dispensible in this role).

 

It will be very exciting to elucidate the other functions of eosinophils during my time at Monash.

External positions

Research Associate, University of Glasgow

31 Oct 201631 Dec 2017

PhD student, The University of Edinburgh

20122016

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Research Output 2000 2018

  • 6 Article
  • 2 Review Article
  • 1 Comment / Debate

Technical challenges of working with extracellular vesicles

Ramirez, M. I., Amorim, M. G., Gadelha, C., Milic, I., Welsh, J. A., Freitas, V. M., Nawaz, M., Akbar, N., Couch, Y., Makin, L., Cooke, F., Vettore, A. L., Batista, P. X., Freezor, R., Pezuk, J. A., Rosa-Fernandes, L., Carreira, A. C. O., Devitt, A., Jacobs, L., Silva, I. T. & 5 othersCoakley, G., Nunes, D. N., Carter, D., Palmisano, G. & Dias-Neto, E., 21 Jan 2018, In : Nanoscale. 10, 3, p. 881-906 26 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

Extracellular Vesicles from a Helminth Parasite Suppress Macrophage Activation and Constitute an Effective Vaccine for Protective Immunity

Coakley, G., McCaskill, J. L., Borger, J. G., Simbari, F., Robertson, E., Millar, M., Harcus, Y., McSorley, H. J., Maizels, R. M. & Buck, A. H., 23 May 2017, In : Cell Reports. 19, 8, p. 1545-1557 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Host parasite communications—Messages from helminths for the immune system: Parasite communication and cell-cell interactions

Coakley, G., Buck, A. H. & Maizels, R. M., 1 Jul 2016, In : Molecular and Biochemical Parasitology. 208, 1, p. 33-40 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Plasmalogen enrichment in exosomes secreted by a nematode parasite versus those derived from its mouse host: Implications for exosome stability and biology

Simbari, F., McCaskill, J., Coakley, G., Millar, M., Maizels, R. M., Fabri�s, G., Casas, J. & Buck, A. H., 2016, In : Journal of Extracellular Vesicles. 5, 1, 17 p., 30741.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Cultivation of Heligmosomoides polygyrus: An immunomodulatory nematode parasite and its secreted products

Johnston, C. J. C., Robertson, E., Harcus, Y., Grainger, J. R., Coakley, G., Smyth, D. J., McSorley, H. J. & Maizels, R., 6 Apr 2015, In : Journal of Visualized Experiments. 2015, 98, 10 p., e52412.

Research output: Contribution to journalArticleOtherpeer-review