Gill Matthewson's research focuses on gender and architecture. She has a background as a practising architect in Britain and New Zealand and continues to design. 

The most recent manifestation of Gill's research into gender and architecture has been investigating the impact of the gendering of space on how sex, gender and sexuality may limit who and what contributes to the production of, and participation in, the spatial culture of cities. Her particular skills are quantitative and qualitative data analysis and visualisation to highlight these impacts.

Gill's PhD thesis 'Dimensions of Gender: women's careers in the Australian architecture profession' was conferred by the University of Queensland and received a Dean's award for outstanding thesis. This research was both quantitative - mapping the participation of women in the Australian profession - and qualitative - involving ethnographic research into aspects of the work culture of the profession that produced gender bias.

Gill is also a director of the Parlour collective, the activist website promoting equity and diversity in the architecture profession. She has become known as the foremost 'counter' of the architecture profession in Australia, continuing the quantitative work of her PhD.