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Research Output 1991 2019

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Article
2019

Cytarabine-based induction immunochemotherapy in the front-line treatment of older patients with mantle cell lymphoma

Ratnasingam, S., Casan, J., Shortt, J., Hawkes, E., Gilbertson, M., McQuilten, Z., Grigoriadis, G., Htun, K. T., Htet, S. M., Campbell, P., Chai, K. L., Quach, H., Patil, S. & Opat, S., 19 Sep 2019, In : Scientific Reports. 9, 1, 7 p., 13544.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2018
1 Citation (Scopus)

DCEP as a bridge to ongoing therapies for advanced relapsed and/or refractory multiple myeloma

Yuen, H. L. A., Low, M. S. Y., Fedele, P., Kalff, A., Walker, P., Bergin, K., Coutsouvelis, J., Grigoriadis, G. & Spencer, A., 2 Dec 2018, In : Leukemia and Lymphoma. 59, 12, p. 2842-2846 5 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Failure to achieve early disease response is associated with inferior survival in patients with newly diagnosed multiple myeloma

Chee, A., Low, M. S., Vilcassim, S., Gregory, G. P., Gilbertson, M., Ratnasingam, S., Grigoriadis, G. & Fedele, P. L., Sep 2018, In : British Journal of Haematology. 182, 5, p. 739-741 3 p.

Research output: Contribution to journalArticleOtherpeer-review

8 Citations (Scopus)

IMiDs prime myeloma cells for daratumumab-mediated cytotoxicity through loss of Ikaros and Aiolos

Fedele, P. L., Willis, S. N., Liao, Y., Low, M. S., Rautela, J., Segal, D. H., Gong, J. N., Huntington, N. D., Shi, W., Huang, D. C. S., Grigoriadis, G., Tellier, J. & Nutt, S. L., 15 Nov 2018, In : Blood. 132, 20, p. 2166-2178 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2017
1 Citation (Scopus)

Immune thrombocytopenic purpura associated with fingolimod

Yuen, H. L. A., Brown, S., Chan, N. & Grigoriadis, G., 1 Jan 2017, In : BMJ Case Reports. 2017, 5 p.

Research output: Contribution to journalArticleOtherpeer-review

2 Citations (Scopus)

Improving the Transition to Palliative Care for Patients With Acute Leukemia: A Coordinated Care Approach

Hopkins, B., Gold, M., Wei, A. & Grigoriadis, G., May 2017, In : Cancer Nursing. 40, 3, p. E17-E23 7 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Treatment of patients with Waldenström macroglobulinaemia: clinical practice guidelines from the Myeloma Foundation of Australia Medical and Scientific Advisory Group

Talaulikar, D., Tam, C. S., Joshua, D. E., Ho, P. J., Szer, J., Quach, H., Spencer, A., Harrison, S. J., Mollee, P., Roberts, A. W., Horvath, N., Lee, C., Zannettino, A. C. W., Brown, R. D., Augustson, B. M., Jaksic, W. J., Gibson, J., Kalff, A., Johnston, A., Trotman, J. & 4 others, Kalro, A., Grigoriadis, G., Ward, C. & Prince, H. M., 1 Jan 2017, In : Internal Medicine Journal. 47, 1, p. 35-49 15 p.

Research output: Contribution to journalArticleOtherpeer-review

2016
2 Citations (Scopus)

Anabolic androgenic steroids, an easily forgotten cause of polycythaemia and cerebral infarction

Low, M. S. Y., Vilcassim, S., Fedele, P. & Grigoriadis, G., 1 Apr 2016, In : Internal Medicine Journal. 46, 4, p. 497-499 3 p.

Research output: Contribution to journalArticleOtherpeer-review

18 Citations (Scopus)

NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells

de Valle, E., Grigoriadis, G., O'Rielly, L. A., Willis, S. N., Maxwell, M. J., Corcoran, L. M., Tsantikos, E., Cornish, J. K. S., Fairfax, K. A., Vasanthakumar, A., Febbraio, M. A., Hibbs, M. L., Pellegrini, M., Banerjee, A., Hodgkin, P. D., Kallies, A., Mackay, F., Strasser, A., Gerondakis, S. & Gugasyan, R., 4 Apr 2016, In : Journal of Experimental Medicine. 213, 4, p. 621-641 21 p., PMC4821646.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Profiling clinical platelet and plasma use to inform blood supply and contingency planning: PUPPY, the prospective utilization of platelets and plasma study

Fedele, P. L., Polizzotto, M. N., Grigoriadis, G., Waters, N., Comande, M., Borosak, M., Portbury, D. & Wood, E. M., Oct 2016, In : Transfusion. 56, p. 2455-2465 11 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Rivaroxaban in treatment refractory heparin-induced thrombocytopenia

Casan, J. M. L., Grigoriadis, G., Chan, N. C. & Chunilal, S., 12 Aug 2016, In : BMJ Case Reports. 2016, Aug 12, 3 p.

Research output: Contribution to journalArticleOtherpeer-review

13 Citations (Scopus)

The SMAC mimetic, LCL-161, reduces survival in aggressive MYC-driven lymphoma while promoting susceptibility to endotoxic shock

West, A. C., Martin, B. P., Andrews, D. A., Hogg, S. J., Banerjee, A., Grigoriadis, G., Johnstone, R. W. & Shortt, J., 4 Apr 2016, In : Oncogenesis. 5, 6 p., e216.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2015

Numerous Howell-Jolly bodies in a patient with idiopathic splenic calcification

Cummins, K. D., Westall, G. P. & Grigoriadis, G., 1 Jun 2015, In : British Journal of Haematology. 169, 6, p. 767 1 p.

Research output: Contribution to journalArticleOtherpeer-review

5 Citations (Scopus)

PAX5-expressing ALK-negative anaplastic large cell lymphoma with extensive extranodal and nodal involvement

Ong, D. M., Cummins, K. D., Pham, A. & Grigoriadis, G., 17 Jul 2015, In : BMJ Case Reports. 2015, 211159.

Research output: Contribution to journalArticleOtherpeer-review

23 Citations (Scopus)

The oral iron chelator deferasirox inhibits NF-kappaB mediated gene expression without impacting on proximal activation: implications for myelodysplasia and aplastic anaemia

Banerjee, A., Mifsud, N. A., Bird, R. J., Forsyth, C. J., Szer, J., Tam, C., Kellner, S. V., Grigg, A. P., Motum, P., Bentley, M., Opat, S. & Grigoriadis, G., 2015, In : British Journal of Haematology. 168, 4, p. 576 - 582 7 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

The role of multiparametric flow cytometry in the detection of minimal residual disease in acute leukaemia

Lee, D., Grigoriadis, G. & Westerman, D. A., 2015, In : Pathology. 47, 7, p. 609 - 621 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2013
8 Citations (Scopus)

Fludarabine, cytarabine, granulocyte-colony stimulating factor and amsacrine: an effective salvage therapy option for acute myeloid leukemia at first relapse

Fong, C. Y., Grigoriadis, G., Hocking, J., Coutsouvelis, J., Muirhead, J. L., Campbell, P., Paul, E., Walker, P. A., Avery, S., Patil, S., Spencer, A., Schwarer, A. & Wei, A., 2013, In : Leukemia and Lymphoma. 54, 2, p. 336 - 341 6 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Modulating T regulatory cells in cancer: how close are we?

Banerjee, A., Vasanthakumar, A. & Grigoriadis, G., 2013, In : Immunology and Cell Biology. 91, 5, p. 340 - 349 10 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Thymic regulatory T cell development: role of signalling pathways and transcription factors

Engel, M., Sidwell, T., Vasanthakumar, A., Grigoriadis, G. & Banerjee, A., 2013, In : Clinical and Developmental Immunology. 2013, Art # e617585, p. 1 - 9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2012
52 Citations (Scopus)

Detection of BRAF mutations in patients with hairy cell leukemia and related lymphoproliferative disorders

Blombery, P., Wong, S. Q., Hewitt, C. A., Dobrovic, A., Maxwell, E., Juneja, S., Grigoriadis, G. & Westerman, D. A., 2012, In : Haematologica: the hematology journal. 97, 5, p. 780 - 783 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Failure of haematopoietic recovery overcome by SCT despite invasive mucormycosis infection

Grigoriadis, G., Chang, C. C., Walker, P., Patil, S., Avery, S., Morrissey, O. & Spencer, A., 2012, In : Bone Marrow Transplantation. 47, p. 591 - 592 2 p.

Research output: Contribution to journalArticleOtherpeer-review

7 Citations (Scopus)

Is CD20 positive plasma cell myeloma a unique clinicopathological entity? A study of 40 cases and review of the literature

Grigoriadis, G., Gilbertson, M., Came, N., Westerman, D. A., Fellepa, F., Jene, N., Chapple, P. & Juneja, S., 2012, In : Pathology. 44, 6, p. 552 - 556 5 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

NF-k(kappa)B subunit specificity in hemopoiesis.

Gerondakis, S. D., Banerjee, A., Grigoriadis, G., Vasanthakumar, A., Gugasyan, R., Sidwell, T. & Grumont, R. J., 2012, In : Immunological Reviews. 246, 1, p. 272 - 285 14 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

The NF-[kappa]B1 transcription factor prevents the intrathymic development of CD8 T cells with memory properties

Gugasyan, R., Horat, E., Kinkel, S., Ross, F., Grigoriadis, G., Gray, D., O'Keeffe, M., Berzins, S., Belz, G., Grumont, R., Banerjee, A., Strasser, A., Godfrey, D., Tsichlis, P. & Gerondakis, S., 2012, In : EMBO Journal. 31, 3, p. 692 - 706 15 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Tumor progression locus 2 (Tpl2) deficiency does not protect against obesity-induced metabolic disease

Lancaster, G. I., Kowalski, G., Estevez, E., Kraakman, M. J., Grigoriadis, G., Febbraio, M. A., Gerondakis, S. D. & Banerjee, A., 2012, In : PLoS ONE. 7, 6, 7 p., e39100.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2011
52 Citations (Scopus)

Coagulation-induced shedding of platelet glycoprotein VI mediated by factor Xa

Al-Tamimi, M., Grigoriadis, G., Tran, H., Paul, E., Servadei, P., Berndt, M., Gardiner, E. E. & Andrews, R. K., 2011, In : Blood. 117, 14, p. 3912 - 3920 9 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

C-rel controls multiple discrete steps in the thymic development of Foxp3+ CD4 regulatory T cells

Grigoriadis, G., Vasanthakumar, A., Banerjee, A., Grumont, R. J., Overall, S., Gleeson, P. A., Shannon, M. & Gerondakis, S., 2011, In : PLoS ONE. 6, 10, 10 p., e26851.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
4 Citations (Scopus)

Persistent complement-dependent anti-AnWj in a lymphoproliferative disorder: A case study and review

Grigoriadis, G., Condon, J., Green, K., Anderson, M. A., Borosak, M. & Wood, E., 2011, In : Immunohematology. 27, 3, p. 83 - 88 6 p.

Research output: Contribution to journalArticleOther

2010
13 Citations (Scopus)

Deactylase inhibition in myeloproliferative neoplasms

Mithraprabhu, S., Grigoriadis, G., Khong, T. & Spencer, A., 2010, In : Investigational New Drugs. 28, Suppl 1, p. 50 - 57 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2004
66 Citations (Scopus)

The transcription factors c-rel and RelA control epidermal development and homeostasis in embryonic and adult skin via distinct mechanisms

Gugasyan, R., Voss, A. K., Varigos, G., Thomas, T., Grumont, R. J., Kaur, P., Grigoriadis, G. & Gerondakis, S. D., 2004, In : Molecular and Cellular Biology. 24, 13, p. 5733 - 5745 13 p.

Research output: Contribution to journalArticleResearchpeer-review

1999
42 Citations (Scopus)

Mice lacking the transcription factor subunit Rel can clear an influenza infection and have functional anti-viral cytotoxic T cells but do not develop an optimal antibody response

Harling-McNabb, L., Deliyannis, G., Jackson, D. C., Gerondakis, S. D., Grigoriadis, G. & Brown, L. E., 1999, In : International Immunology. 11, 9, p. 1431 - 1439 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1996
125 Citations (Scopus)

Rel-deficient T cells exhibit defects in production of interleukin 3 and granulocyte-macrophage colony-stimulating factor

Gerondakis, S. D., Strasser, A., Metcalf, D., Grigoriadis, G., Scheerlinck, J-P. Y. & Grumont, R. J., 1996, In : Proceedings of the National Academy of Sciences. 93, 8, p. 3405 - 3409 5 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Role of tyrosine phosphorylation in the signalling of superoxide anion generation in platelet-activating-factor-stimulated peritoneal macrophages

Grigoriadis, G. & Stewart, A. G., 1996, In : Cellular Physiology and Biochemistry. 6, 5, p. 271 - 282 12 p.

Research output: Contribution to journalArticleResearchpeer-review

86 Citations (Scopus)

The Rel subunit of NF-I?B-like transcription factors is a positive and negative regulator of macrophage gene expression: Distinct roles for Rel in different macrophage populations

Grigoriadis, G., Zhan, Y., Grumont, R. J., Metcalf, D., Handman, E., Cheers, C. & Gerondakis, S. D., 1996, In : EMBO Journal. 15, 24, p. 7099 - 7107 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1994
53 Citations (Scopus)

Mitogenic actions of endothelin-1 and epidermal growth factor in cultured airway smooth muscle

Stewart, A. G., Grigoriadis, G. & Harris, T., 1994, In : Clinical and Experimental Pharmacology and Physiology. 21, 4, p. 277 - 285 9 p.

Research output: Contribution to journalArticleResearchpeer-review

48 Citations (Scopus)

Physiological and pathophysiological roles of nitric oxide

Stewart, A. G., Phan, L. H. & Grigoriadis, G., 1994, In : Microsurgery. 15, 10, p. 693 - 702 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Platelet-activation products, but not PAF are mitogenic for cultured airway smooth muscle

Stewart, A. G., Grigoriadis, G. & Harris, T., 1994, In : Journal of Lipid Mediators and Cell Signalling. 10, 1-2, p. 61-62 2 p.

Research output: Contribution to journalArticleResearchpeer-review

1993
1 Citation (Scopus)

Importance of basal and agonist-stimulated intracellular calcium for superoxide anion generation in peritoneal macrophages

Grigoriadis, G., Lim, W. & Stewart, A. G., 1993, In : Cellular Physiology and Biochemistry. 3, 2, p. 117 - 126 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1992
25 Citations (Scopus)

Albumin inhibits platelet-activating factor (PAF)-induced responses in platelets and macrophages: Implications for the biologically active form of PAF

Grigoriadis, G. & Stewart, A. G., 1992, In : British Journal of Pharmacology. 107, 1, p. 73 - 77 5 p.

Research output: Contribution to journalArticleResearchpeer-review

1991
17 Citations (Scopus)

1-O-hexadecyl-2-acetyl-sn-glycero-3-phospho (N,N,N trimethyl) hexanolamine: An analogue of platelet-activating factor with partial agonist activity

Grigoriadis, G. & Stewart, A. G., 1991, In : British Journal of Pharmacology. 104, 1, p. 171 - 177 7 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Structure-activity relationships for platelet-activating factor (PAF) and analogues reveal differences between PAF receptors on platelets and macrophages

Stewart, A. G. & Grigoriadis, G., 1991, In : Journal of Lipid Mediators. 4, 3, p. 299 - 308 10 p.

Research output: Contribution to journalArticleResearchpeer-review