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20002024

Research activity per year

Personal profile

Biography

A/Prof Georg Ramm is a Chan Zuckerberg Initiative Imaging Scientist and a group leader in the Department of Biochemistry at Monash University. Georg trained as a microscopist, cell biologist, and biochemist during a PhD at Utrecht University in the Netherlands, and during undergraduate and diploma degrees in Germany. He established the Monash Ramaciotti Centre for Cryo-EM, which enables both cell and structural biology EM with imaging expertise in immuno EM, correlative light and electron microscopy, volume imaging, single particle cryo-EM and cryo-tomography. The Ramaciotti Centre is now a major EM Centre in Australia with over 280 users from Australia and overseas including the US, UK, Germany, Israel, New Zealand, and Singapore. He has published in leading journals including in Science, Cell Metabolism, Nature Communications, Autophagy, and the Journal of Cell Biology. 

Research interests

The Ramm lab is focused on high-resolution imaging of cellular architecture and intracellular trafficking. The lab uses cryo-tomography (on Titan Krios) in combination with cryo-focused ion beam milling (cryo-FIB on cryo-Helios) to reveal cellular structures at the highest resolution. The major focus is on fundamental cell biological problems that are relevant to human diseases. This includes the intracellular degradation of organelles by autophagy and mitophagy, mitochondrial ultrastructure and dynamics in healthy and stressed cells, and cellular structural changes during cell death. 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 9 - Industry, Innovation, and Infrastructure
  • SDG 13 - Climate Action

Research area keywords

  • microscopy
  • imaging
  • protein trafficking
  • cryo EM
  • cancer
  • diabetes

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or