Projects per year
Personal profile
Biography
Gan obtained her undergraduate degree in pharmacy from Manchester University, England and subsequent higher qualifications (M. Pharm and PhD) from Universiti Sains Malaysia (USM). Upon completion of her PhD in 2003, she joined the Medical School in USM and headed the Pharmacology Department (Dec 2007-Jan 2009). Subsequently she became the Director of Human Genome Centre (Mac 2009- Jan 2013) before being promoted to a Professor (2014). She joined Monash University Malaysia as a Professor in Pharmacy in Jan 2018 after serving in USM for 18 years.
To date, Gan has received various fundings from national and international agencies including WHO, TWAS-COMSTECH (UNESCO), e-science, FRGS, Research University (RU) (Team), RU (individual), APEX Delivering excellence, Dana Inovasi Awal, Industrial, short term and Research Acculturation Collaborative Effort grants amounting to RM 5.8 million. She has successfully supervised 15 PhD and 3 MSc students some of whom have worked/ are working with John Hopkins and also National University of Singapore (NUS) as post-doctoral fellows indicating the good quality of postgraduates produced.
Together with her collaborators in Universiti Sains Malaysia, Jahangirnagar University (Bangladesh), Griffith University (Australia), Santiago University (Spain), Lahore University (Pakistan) and several more, she has published more than 200 WOS-indexed papers with more than 60% of papers that are internationally-collaborated. Gan is an avid writer and has also written more than 10 books (including 5 children books). She has also published some book chapters (in both Bahasa Malaysia and English) published by Springer, Elsevier, Wiley-Blackwell, MPH publishers, Kanyin, Zi Publishers, Penerbit USM and Dewan Bahasa & Pustaka and is a Cochrane translator (English-Malay-English).
Gan serves on the editorial board of several journals such as Seminars in Cancer Biology, Frontiers in Pharmacology, PlosOne journal, International Journal of Hypertension, Current Chemical Genomics & Translational Medicine, World Journal of Medical Genetics and Evidence-Based Complementary Alternative Medicine.
Gan is a life member of Malaysian Pharmaceutical Society, Malaysian Natural Products Society and Malaysian Society of Infectious Disease & Chemotherapy. She is also a member of Association Clinical Biochemist, Malaysian Society for Biochemistry & Molecular Biology, Malaysian Society of Pharmacology & Physiology, Institute of Food Technologists, Human Genome Organisation, Association of Malaysian Medical Editors (AMMJE), Asia Pacific Association of Medical Journal Editors (APAME) and a member of SIRIM (Malaysia Department of Standard) working group for nanotechnology.
Gan is a trainer for scientific writing and professional development programmes including presentation skills, viva defense & time management. She has been conducting workshops in several institutions in Malaysia (since 2005) as well as in India (in 2017). Her area of specialisations include pharmacogenetics, toxicology and natural products. She is very happy to collaborate, nationally and internationally.
Research interests
Gan has strong interest in pharmacokinetic analysis using high performance liquid chromatography (HPLC). To date she has successfully developed detection method for various analgesics (tramadol, fentanyl, morphine), anti-diabetics (repaglinide, metformin), malaria (artesunate, amodiaquine), anicoagulant (warfarin),anti-hypertensive (propanolol), anticancer (arabinoside-C, imatinib, doxorubin) and other substances including paraquat and amphetamine-type stimulants. She has also developed detection methods for various alleles present in Asian populations including for CYP2D6, CYP3A4, CYP2C9, CYP2A6 dan CYP2C8 genes by using polymerase chain reaction (PCR) for pharmacogenetic studies. Currently, Gan has also embarked on natural products research and have interests in analysis of honey quality and potential therapeutic activities of various components in honey and honey products including propolis, bee venom and royal jelly.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Toxicology
- Natural products
- Pharmacogenetics of CYP
Collaborations and top research areas from the last five years
Projects
- 1 Finished
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Understanding the crosstalk between salivary amylase, oral and gut microbiome, as well as host metabolome in intestinal inflammation and their association with obesity and overweight in Malaysia
Chun Wie, C., Rahman, S., Siew Hua, G., Su, T. T., Ayub, Q. & Creek, D.
1/11/20 → 31/10/23
Project: Research
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Antimicrobial Properties of Honey
Sekar, M., Zuraini, N. Z. A., Rani, N. N. I. M., Lum, P. T. & Hua Gan, S., Apr 2023, Honey: Composition and Health Benefits. Khalil, M. I., Hua, G. S. & Goh, B. H. (eds.). 1st ed. Hoboken NJ USA: John Wiley & Sons, p. 186-196 11 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
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A preliminary study on phenolics, antioxidant and antibacterial activities of Acacia mangium and Garcinia mangostana propolis collected by Geniotrigona thoracica
Maroof, K., Chen, K. F., Lee, R. F. S., Goh, B. H., Mahendra, C. K., Siow, L. F. & Gan, S. H., Oct 2023, In: Food Chemistry Advances. 2, 8 p., 100255.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Celastrol: A Potential Natural Lead Molecule for New Drug Design, Development and Therapy for Memory Impairment
Amir Yusri, M. A., Sekar, M., Wong, L. S., Gan, S. H., Ravi, S., Subramaniyan, V., Mat Rani, N. N. I., Chidambaram, K., Begum, M. Y., Ramar, M., Safi, S. Z., Selvaraj, S., Wu, Y. S., Revathy, P., Fuloria, S., Fuloria, N. K., Lum, P. T. & Djearamane, S., Apr 2023, In: Drug Design, Development and Therapy. 17, p. 1079-1096 18 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access1 Citation (Scopus) -
Chemistry, Biosynthesis and Pharmacology of Streptonigrin: An Old Molecule with Future Prospects for New Drug Design, Development and Therapy
Nabihah Nasir, N., Sekar, M., Ravi, S., Wong, L. S., Sisinthy, S. P., Gan, S. H., Subramaniyan, V., Chidambaram, K., Mat Rani, N. N. I., Begum, M. Y., Ramar, M., Safi, S. Z., Selvaraj, S., Chinna Maruthu, S. K., Fuloria, S., Fuloria, N. K., Lum, P. T. & Djearamane, S., Apr 2023, In: Drug Design, Development and Therapy. 17, p. 1065-1078 14 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access1 Citation (Scopus) -
Clinical pharmacists’ intervention on pain management in cancer patients (PharmaCAP trial): study protocol for a randomized controlled trial
Shrestha, S., Blebil, A. Q., Teoh, S. L., Sapkota, S., Kc, B., Paudyal, V. & Gan, S. H., 2023, In: Journal of Pharmaceutical Policy and Practice. 16, 1, 12 p., 14.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile3 Citations (Scopus)
Prizes
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Silver Medal at the 33th International Invention, Innovation and Technology Exhibition Malaysia for the invention "SFE Kelulut Golden Propolis Liquid"
Lee, Ronald (Recipient), Siew Hua, Gan (Recipient), Goh, Bey Hing (Recipient), Maroof, Kashif (Recipient) & Lee Fong, Siow (Recipient), 2022
Prize: Prize (including medals and awards)