• 19 Innovation Walk, Level 3

    3800 Clayton

    Australia

Accepting PhD Students

PhD projects

Patient-Derived Xenograft Models for Bladder Cancer

1981 …2020

Research output per year

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Research Output

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Article
Article

11 Intragonadal control mechanisms

Findlay, J. K. & Risbridger, G. P., 1987, In : Bailliere's Clinical Endocrinology and Metabolism. 1, 1, p. 223-243 21 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

17beta-Estradiol induces apoptosis in the developing rodent prostate independently of ERalpha or ERbeta

Taylor, R. A., Cowin, P. A., Couse, J. F., Korach, K. S. & Risbridger, G. P., 2006, In : Endocrinology. 147, 1, p. 191 - 200 10 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

6 The physiology of testicular inhibin and related proteins

Robertson, D. M., Risbridger, G. P. & de Kretser, D. M., 1992, In : Bailliere's Clinical Endocrinology and Metabolism. 6, 2, p. 355-372 18 p.

Research output: Contribution to journalArticleOtherpeer-review

8 Citations (Scopus)

A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer

Clark, A. K., Taubenberger, A. V., Taylor, R. A., Niranjan, B., Chea, Z. Y., Zotenko, E., Sieh, S., Pedersen, J. S., Norden, S., Frydenberg, M., Grummet, J., Pook, D. W., Stirzaker, C., Clark, S., Lawrence, M. G., Ellem, S. J., Hutmacher, D. & Risbridger, G. P., 2013, In : Biomaterials. 34, 20, p. 4777 - 4785 9 p.

Research output: Contribution to journalArticleResearchpeer-review

38 Citations (Scopus)

A comparative assessment of alpha-lipoic acid N-phenylamides as non-steroidal androgen receptor antagonists both on and off gold nanoparticles

Henderson, L. C., Altimari, J. M., Dyson, G., Servinis, L., Niranjan, B. & Risbridger, G. P., 2012, In : Bioorganic Chemistry. 40, 1, p. 1 - 5 5 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

A critical role for estrogen signaling in penis development

Govers, L. C., Phillips, T. R., Mattiske, D. M., Rashoo, N., Black, J. R., Sinclair, A., Baskin, L. S., Risbridger, G. P. & Pask, A. J., Sep 2019, In : The FASEB Journal. 33, 9, p. 10383-10392 10 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Activin-{beta}C modulates cachexia by repressing the ubiquitin-proteasome and autophagic degradation pathways

Marino, F. E., Risbridger, G. P. & Gold, E. J., 2015, In : Journal of Cachexia, Sarcopenia and Muscle. 6, 4, p. 365 - 380 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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15 Citations (Scopus)

Activin-beta(c) reduces reproductive tumour progression and abolishes cancer-associated cachexia in inhibin-deficient mice

Gold, E., Marino, F. E., Harrison, C., Makanji, Y. & Risbridger, G. P., 2013, In : Journal of Pathology. 229, 4, p. 599 - 607 9 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Activin-betaC modulates gonadal, but not adrenal tumorigenesis in the inhibin deficient mice

Marino, F. E., Risbridger, G. P. & Gold, E. J., 2015, In : Molecular and Cellular Endocrinology. 409, p. 41 - 50 10 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Activin beta c-subunit heterodimers provide a new mechanism of regulating activin levels in the prostate

Mellor, S. L., Ball, E. M. A., O'Connor, A. E., Ethier, J-F., Cranfield, M., Schmitt, J. F., Phillips, D. J., Groome, N. P. & Risbridger, G. P., 2003, In : Endocrinology. 144, 10, p. 4410 - 4419 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Activin C antagonizes activin A in vitro and overexpression leads to pathologies in vivo

Gold, E. J., Jetly, N., O'Bryan, M. K., Meachem, S. J., Srinivasan, D., Behuria, S., Sanchez-Partida, L. G., Woodruff, T. K., Hedwards, S. L., Wang, H., McDougall, H., Casey, V., Niranjan, B., Patella, S. & Risbridger, G. P., 2009, In : American Journal of Pathology. 174, 1, p. 184 - 195 12 p.

Research output: Contribution to journalArticleResearchpeer-review

48 Citations (Scopus)

Activins and activin antagonists in the prostate and prostate cancer

Gold, E. & Risbridger, G. P., 2012, In : Molecular and Cellular Endocrinology. 359, 1-2, p. 107 - 112 6 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Activins and inhibins in endocrine and other tumors

Risbridger, G. P., Schmitt, J. F. & Robertson, D. M., 2001, In : Endocrine Reviews. 22, 6, p. 836 - 858 23 p.

Research output: Contribution to journalArticleResearchpeer-review

157 Citations (Scopus)

Activins are regulators of branching morphogenesis

Ball, E. M. A. & Risbridger, G. P., 2001, In : Developmental Biology. 238, 1, p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

76 Citations (Scopus)

Activin βC-subunit heterodimers provide a new mechanism of regulating activin levels in the prostate

Mellor, S. L., Ball, E. M. A., O'Connor, A. E., Ethier, J. F., Cranfield, M., Schmitt, J. F., Phillips, D. J., Groome, N. P. & Risbridger, G. P., 1 Oct 2003, In : Endocrinology. 144, 10, p. 4410-4419 10 p.

Research output: Contribution to journalArticleResearchpeer-review

52 Citations (Scopus)
11 Citations (Scopus)
24 Citations (Scopus)

Age Related Differences in Responsiveness to Sildenafil and Tamsulosin are due to Myogenic Smooth Muscle Tone in the Human Prostate

Lee, S. N., Chakrabarty, B., Wittmer, B., Papargiris, M., Ryan, A., Frydenberg, M., Frydenberg, M., Lawrentschuk, N., Middendorff, R., Risbridger, G. P., Ellem, S. J. & Exintaris, B., 1 Dec 2017, In : Scientific Reports. 7, 1, 9 p., 10150.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

A large-scale analysis of genetic variants within putative miRNA binding sites in prostate cancer

Stegeman, S., Amankwah, E., Klein, K., O’Mara, T. A., Kim, D., Lin, H-Y. L., Permuth-Wey, J., Sellers, T. A., Srinivasan, S., Eeles, R. A., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Wiklund, F., Gronberg, H., Haiman, C. A., Schleutker, J. & 2 others, PRACTICAL Consortium & Australian Prostate Cancer BioResource, 1 Apr 2015, In : Cancer Discovery. 5, 4, p. 368-379 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
33 Citations (Scopus)

A loss of estrogen signaling in the aromatase deficient mouse penis results in mild hypospadias

Cripps, S. M., Mattiske, D. M., Black, J. R., Risbridger, G. P., Govers, L. C., Phillips, T. R. & Pask, A. J., Sep 2019, In : Differentiation. 109, p. 42-52 11 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Alterations in mitogenic and steroidogenic activities in rat testicular interstitial fluid after administration of ethane dimethane sulphonate

Drummond, A. E., Risbridger, G. P., O'Leary, P. C. & De Kretser, D. M., 1988, In : Journal of Reproduction and Fertility. 83, 1, p. 141-147 7 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer

Lawrence, M. G., Pidsley, R., Niranjan, B., Papargiris, M., Pereira, B. A., Richards, M., Teng, L., Norden, S., Ryan, A., Frydenberg, M., Stirzaker, C., Taylor, R. A., Risbridger, G. P. & Clark, S. J., 18 Mar 2020, In : Clinical Epigenetics. 12, 1, 18 p., 48.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Analysis of the effect of estrogen/androgen perturbation on penile development in transgenic and diethylstilbestrol-treated mice

Blaschko, S. D., Mahawong, P., Ferritti, M., Cunha, T. J., Sinclair, A., Wang, H., Schlomer, B. J., Risbridger, G. P., Baskin, L. S. & Cunha, G. R., 2013, In : Anatomical Record. 296, 7, p. 1127 - 1141 15 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

An assessment of leydig cell function after bilateral or unilateral efferent duct ligation: Further evidence for local control of leydig cell function

Risbridger, G. P., Kerr, J. B., Peake, R. A. & Kretser, D. M. D., 1981, In : Endocrinology. 109, 4, p. 1234-1241 8 p.

Research output: Contribution to journalArticleResearchpeer-review

58 Citations (Scopus)

An in vivo model of prostrate carcinoma growth and invasion in bone

Fisher, J. L., Schmitt, J. F., Howard, M. L., Mackie, P. S., Choong, P. FM. & Risbridger, G. P., 2002, In : Cell and Tissue Research. 307, p. 337 - 345 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Anti-androgenic action by red clover-derived dietary isoflavones reduces non-malignant prostate enlargement in aromatase knockout (ArKO) mice

Jarred, R. A., McPherson, S. J., Jones, M. E. E., Simpson, E. R. & Risbridger, G. P., 2003, In : Prostate. 56, p. 54 - 64 11 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

A preclinical xenograft model identifies castration-tolerant cancer-repopulating cells in localized prostate tumors

Toivanen, R., Frydenberg, M., Murphy, D., Pedersen, J. S., Ryan, A., Pook, D. W., Berman, D. M., Taylor, R. A. & Risbridger, G. P., 2013, In : Science Translational Medicine. 5, 187 (Art. No.:187ra71), p. 1 - 7 7 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

A preclinical xenograft model of prostate cancer using human tumors

Lawrence, M. G., Taylor, R. A., Toivanen, R., Pedersen, J. S., Norden, S., Pook, D. W., Frydenberg, M., Australian Prostate Cancer BioResource, Papargiris, M., Niranjan, B., Richards, M. G., Wang, H., Collins, A. T., Maitland, N. J. & Risbridger, G. P., 2013, In : Nature Protocols. 8, 5, p. 836 - 848 13 p.

Research output: Contribution to journalArticleResearchpeer-review

65 Citations (Scopus)

A pro-tumourigenic loop at the human prostate tumour interface orchestrated by oestrogen, CXCL12 and mast cell recruitment

Ellem, S. J., Taylor, R. A., Furic, L., Larsson, O., Frydenberg, M., Pook, D. W., Pedersen, J. S., Cawsey, B., Trotta, A., Need, E. F., Buchanan, G. & Risbridger, G. P., 2014, In : Journal of Pathology. 234, 1, p. 86 - 98 13 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

A rare castration-resistant progenitor cell population is highly enriched in Pten-null prostate tumours

Sackmann Sala, L., Boutillon, F., Menara, G., De Goyon-Pélard, A., Leprévost, M., Codzamanian, J., Lister, N., Pencik, J., Clark, A., Cagnard, N., Bole-Feysot, C., Moriggl, R., Risbridger, G. P., Taylor, R. A., Kenner, L., Guidotti, J. E. & Goffin, V., Sep 2017, In : Journal of Pathology. 243, 1, p. 51-64 14 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Aromatase and prostate cancer

Ellem, S. J. & Risbridger, G. P., 2006, In : Minerva Endocrinologica. 31, 1, p. 1 - 12 12 p.

Research output: Contribution to journalArticleOther

35 Citations (Scopus)

Aromatase and regulating the estrogen: Androgen ratio in the prostate gland

Ellem, S. J. & Risbridger, G. P., 2010, In : Journal of Steroid Biochemistry and Molecular Biology. 118, 4-5, p. 246 - 251 6 p.

Research output: Contribution to journalArticleResearchpeer-review

103 Citations (Scopus)

Aromatase transgenic upregulation modulates basal cardiac performance and the response to ischemic stress in male mice

Bell, J. R., Bernasochi, G. N., Varma, U., Boon, W. C., Ellem, S. J., Risbridger, G. P. & Delbridge, L. M. D., 2014, In : American Journal of Physiology - Heart and Circulatory Physiology. 306, 9, p. 1265 - 1274 10 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

A single nucleotide polymorphism genotyping platform for the authentication of patient derived xenografts

El-Hoss, J., Jing, D., Evans, K., Toscan, C., Xie, J., Lee, H., Taylor, R. A., Lawrence, M. G., Risbridger, G. P., MacKenzie, K. L., Sutton, R. & Lock, R. B., 9 Aug 2016, In : Oncotarget. 7, 37, p. 60475-60490 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

Schumacher, F. R., Al Olama, A. A., Berndt, S. I., Benlloch, S., Ahmed, M., Saunders, E. J., Dadaev, T., Leongamornlert, D., Anokian, E., Cieza-Borrella, C., Goh, C., Brook, M. N., Sheng, X., Fachal, L., Dennis, J., Tyrer, J., Muir, K., Lophatananon, A., Stevens, V. L., Gapstur, S. M. & 167 others, Carter, B. D., Tangen, C. M., Goodman, P. J., Thompson, I. M., Batra, J., Chambers, S., Moya, L., Clements, J., Horvath, L., Tilley, W., Risbridger, G. P., Gronberg, H., Aly, M., Nordström, T., Pharoah, P., Pashayan, N., Schleutker, J., Tammela, T. L. J., Sipeky, C., Auvinen, A., Albanes, D., Weinstein, S., Wolk, A., Håkansson, N., West, C. M. L., Dunning, A. M., Burnet, N., Mucci, L. A., Giovannucci, E., Andriole, G. L., Cussenot, O., Cancel-Tassin, G., Koutros, S., Beane Freeman, L. E., Sorensen, K. D., Orntoft, T. F., Borre, M., Maehle, L., Grindedal, E. M., Neal, D. E., Donovan, J. L., Hamdy, F. C., Martin, R. M., Travis, R. C., Key, T. J., Hamilton, R. J., Fleshner, N. E., Finelli, A., Ingles, S. A., Stern, M. C., Rosenstein, B. S., Kerns, S. L., Ostrer, H., Lu, Y. J., Zhang, H. W., Feng, N., Mao, X., Guo, X., Wang, G., Sun, Z., Giles, G. G., Southey, M. C., MacInnis, R. J., Fitzgerald, L. M., Kibel, A. S., Drake, B. F., Vega, A., Gómez-Caamaño, A., Szulkin, R., Eklund, M., Kogevinas, M., Llorca, J., Castaño-Vinyals, G., Penney, K. L., Stampfer, M., Park, J. Y., Sellers, T. A., Lin, H. Y., Stanford, J. L., Cybulski, C., Wokolorczyk, D., Lubinski, J., Ostrander, E. A., Geybels, M. S., Nordestgaard, B. G., Nielsen, S. F., Weischer, M., Bisbjerg, R., Røder, M. A., Iversen, P., Brenner, H., Cuk, K., Holleczek, B., Maier, C., Luedeke, M., Schnoeller, T., Kim, J., Logothetis, C. J., John, E. M., Teixeira, M. R., Paulo, P., Cardoso, M., Neuhausen, S. L., Steele, L., Ding, Y. C., De Ruyck, K., De Meerleer, G., Ost, P., Razack, A., Lim, J., Teo, S. H., Lin, D. W., Newcomb, L. F., Lessel, D., Gamulin, M., Kulis, T., Kaneva, R., Usmani, N., Singhal, S., Slavov, C., Mitev, V., Parliament, M., Claessens, F., Joniau, S., Van Den Broeck, T., Larkin, S., Townsend, P. A., Aukim-Hastie, C., Dominguez, M. G., Castelao, J. E., Martinez, M. E., Roobol, M. J., Jenster, G., Van Schaik, R. H. N., Menegaux, F., Truong, T., Koudou, Y. A., Xu, J., Khaw, K. T., Cannon-Albright, L., Pandha, H., Michael, A., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., Lindstrom, S., Turman, C., Ma, J., Hunter, D. J., Riboli, E., Siddiq, A., Canzian, F., Kolonel, L. N., Le Marchand, L., Hoover, R. N., Machiela, M. J., Cui, Z., Kraft, P., Amos, C. I., Conti, D. V., Easton, D. F., Wiklund, F., Chanock, S. J., Henderson, B. E., Kote-Jarai, Z., Haiman, C. A. & Eeles, R. A., 1 Jul 2018, In : Nature Genetics. 50, 7, p. 928-936 9 p.

Research output: Contribution to journalArticleResearchpeer-review

118 Citations (Scopus)

A versatile monoclonal antibody specific to human SERPINB5

Teoh, S. SY., Wang, H., Risbridger, G. P., Whisstock, J. C. & Bird, P. I., 2012, In : Hybridoma. 31, 5, p. 333 - 339 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

BetaA- and betaC-activin, follistatin, activin receptor mRNA and betaC-activin peptide expression during rat liver regeneration

Gold, E. J., Zhang, X., Wheatley, A. M., Mellor, S. L., Cranfield, M., Risbridger, G. P., Groome, N. P. & Fleming, J. S., 2005, In : Journal of Molecular Endocrinology. 34, 2, p. 505 - 515 11 p.

Research output: Contribution to journalArticleResearchpeer-review

43 Citations (Scopus)

Breaking through a roadblock in prostate cancer research: An update on human model systems

Toivanen, R., Taylor, R. A., Pook, D. W., Ellem, S. J. & Risbridger, G. P., 2012, In : Journal of Steroid Biochemistry and Molecular Biology. 131, 3-5, p. 122 - 131 10 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Breast and prostate cancer: more similar than different

Risbridger, G. P., Davis, I. D., Birrell, S. N. & Tilley, W. D., 2010, In : Nature Reviews Cancer. 10, 3, p. 205 - 212 8 p.

Research output: Contribution to journalArticleOther

142 Citations (Scopus)

Brief report: A bioassay to identify primary human prostate cancer repopulating cells

Toivanen, R., Berman, D., Wang, H., Pedersen, J. S., Frydenberg, M., Meeker, A., Ellem, S., Risbridger, G. & Taylor, R., 2011, In : Stem Cells. 29, 8, p. 1310 - 1314 5 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Cancer progression: Is inhibin from Venus or Mars?

Ball, E. M. A., Mellor, S. L. & Risbridger, G. P., 2004, In : Cytokine and Growth Factor Reviews. 15, 5, p. 291 - 296 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Cell-specific expression of betaC-activin in the rat reproductive tract, adrenal and liver

Gold, E. J., O'Bryan, M. K., Mellor, S. L., Cranfield, M., Risbridger, G. P., Groome, N. P. & Fleming, J. S., 30 Jul 2004, In : Molecular and Cellular Endocrinology. 222, 1-2, p. 61-69 9 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Cell-specific expression of in the rat reproductive tract, adrenal and liver

Gold, E. J., O'Bryan, M. K., Mellor, S. L., Cranfield, M., Risbridger, G. P., Groome, N. P. & Fleming, J. S., 2004, In : Molecular and Cellular Endocrinology. 222, p. 61 - 69 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Changes in activin and activin receptor subunit expression in rat liver during the development of CCl4-induced cirrhosis

Gold, E. J., Francis, R. J. B., Zimmermann, A., Mellor, S. L., Cranfield, M., Risbridger, G. P., Groome, N. P., Wheatley, A. M. & Fleming, J. S., 2003, In : Molecular and Cellular Endocrinology. 201, 1-Feb, p. 143 - 153 11 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target

Lee, R. S., Zhang, L., Berger, A., Lawrence, M. G., Song, J., Niranjan, B., Davies, R. G., Lister, N. L., Sandhu, S. K., Rubin, M. A., Risbridger, G. P., Taylor, R. A., Rickman, D. S., Horvath, L. G. & Daly, R. J., 1 Apr 2019, In : Neoplasia. 21, 4, p. 389-400 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Commentary: Recent progress in our understanding of inhibin in the prostate gland

Risbridger, G. P., 1998, In : Journal of Endocrinology. 157, 1, p. 1 - 4 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Comparative biomarker expression and RNA integrity in biospecimens derived from radical retropubic and robot-assisted laparoscopic prostatectomies

Ricciardelli, C., Bianco-Miotto, T., Jindal, S., Dodd, T. J., Cohen, P. A., Marshall, V. R., Sutherland, P. D., Samaratunga, H., Kench, J. G., Dong, Y., Wang, H., Clements, J. A., Risbridger, G. P., Sutherland, R. L., Tilley, W. & Horsfall, D. J., 2010, In : Cancer Epidemiology Biomarkers and Prevention. 19, 7, p. 1755 - 1765 11 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels

Lam, D., Luu, P. L., Song, J. Z., Qu, W., Risbridger, G. P., Lawrence, M. G., Lu, J., Trau, M., Korbie, D., Clark, S. J., Pidsley, R. & Stirzaker, C., 22 Jun 2020, In : Clinical Epigenetics. 12, 1, 16 p., 90.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
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