• 19 Innovation Walk, Level 3

    3800 Clayton

    Australia

Accepting PhD Students

PhD projects

Patient-Derived Xenograft Models for Bladder Cancer

1981 …2020

Research output per year

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Research Output

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Article
2020

Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer

Lawrence, M. G., Pidsley, R., Niranjan, B., Papargiris, M., Pereira, B. A., Richards, M., Teng, L., Norden, S., Ryan, A., Frydenberg, M., Stirzaker, C., Taylor, R. A., Risbridger, G. P. & Clark, S. J., 18 Mar 2020, In : Clinical Epigenetics. 12, 1, 18 p., 48.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels

Lam, D., Luu, P. L., Song, J. Z., Qu, W., Risbridger, G. P., Lawrence, M. G., Lu, J., Trau, M., Korbie, D., Clark, S. J., Pidsley, R. & Stirzaker, C., 22 Jun 2020, In : Clinical Epigenetics. 12, 1, 16 p., 90.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
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CRISP3 expression drives prostate cancer invasion and progression

Volpert, M., Furic, L., Hu, J., O'Connor, A. E., Rebello, R. J., Keerthikumar, S., Evans, J., Merriner, D. J., Pedersen, J., Risbridger, G. P., McIntyre, P. & O'Bryan, M. K., 1 Jul 2020, In : Endocrine-Related Cancer. 27, 7, p. 415-430 16 p.

Research output: Contribution to journalArticleResearchpeer-review

2019

A critical role for estrogen signaling in penis development

Govers, L. C., Phillips, T. R., Mattiske, D. M., Rashoo, N., Black, J. R., Sinclair, A., Baskin, L. S., Risbridger, G. P. & Pask, A. J., Sep 2019, In : The FASEB Journal. 33, 9, p. 10383-10392 10 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

A loss of estrogen signaling in the aromatase deficient mouse penis results in mild hypospadias

Cripps, S. M., Mattiske, D. M., Black, J. R., Risbridger, G. P., Govers, L. C., Phillips, T. R. & Pask, A. J., Sep 2019, In : Differentiation. 109, p. 42-52 11 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target

Lee, R. S., Zhang, L., Berger, A., Lawrence, M. G., Song, J., Niranjan, B., Davies, R. G., Lister, N. L., Sandhu, S. K., Rubin, M. A., Risbridger, G. P., Taylor, R. A., Rickman, D. S., Horvath, L. G. & Daly, R. J., 1 Apr 2019, In : Neoplasia. 21, 4, p. 389-400 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Establishing a cryopreservation protocol for patient-derived xenografts of prostate cancer

Porter, L. H., Lawrence, M. G., Wang, H., Clark, A. K., Bakshi, A., Obinata, D., Goode, D., Papargiris, M., Clouston, D., Ryan, A., Norden, S., Corey, E., Nelson, P. S., Isaacs, J. T., Grummet, J., Kourambas, J., Sandhu, S., Murphy, D. G., Pook, D., Frydenberg, M. & 2 others, Taylor, R. A. & Risbridger, G. P., 1 Aug 2019, In : Prostate. 79, 11, p. 1326-1337 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Proteomic profiling of human prostate cancer-associated fibroblasts (CAF) reveals LOXL2-dependent regulation of the tumor microenvironment

Nguyen, E. V., Pereira, B. A., Lawrence, M. G., Ma, X., Rebello, R. J., Chan, H., Niranjan, B., Wu, Y., Ellem, S., Guan, X., Wu, J., Skhinas, J. N., Cox, T. R., Risbridger, G. P., Taylor, R. A., Lister, N. L. & Daly, R. J., 1 Jul 2019, In : Molecular & Cellular Proteomics. 18, 7, p. 1410-1427 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer

Watt, M. J., Clark, A. K., Selth, L. A., Haynes, V. R., Lister, N., Rebello, R., Porter, L. H., Niranjan, B., Whitby, S. T., Lo, J., Huang, C., Schittenhelm, R. B., Anderson, K. E., Furic, L., Wijayaratne, P. R., Matzaris, M., Montgomery, M. K., Papargiris, M., Norden, S., Febbraio, M. & 4 others, Risbridger, G. P., Frydenberg, M., Nomura, D. K. & Taylor, R. A., 6 Feb 2019, In : Science Translational Medicine. 11, 478, 12 p., eaau5758.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Tissue engineered human prostate microtissues reveal key role of mast cell-derived tryptase in potentiating cancer-associated fibroblast (CAF)-induced morphometric transition in vitro

Pereira, B. A., Lister, N. L., Hashimoto, K., Teng, L., Flandes-Iparraguirre, M., Eder, A., Sanchez-Herrero, A., Niranjan, B., Melbourne Urological Research Alliance (MURAL), Frydenberg, M., Papargiris, M. M., Lawrence, M. G., Taylor, R. A., Hutmacher, D. W., Ellem, S. J., Risbridger, G. P. & De-Juan-Pardo, E. M., 1 Mar 2019, In : Biomaterials. 197, p. 72-85 14 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Translational offsetting as a mode of estrogen receptor α-dependent regulation of gene expression

Lorent, J., Kusnadi, E. P., van Hoef, V., Rebello, R. J., Leibovitch, M., Ristau, J., Chen, S., Lawrence, M. G., Szkop, K. J., Samreen, B., Balanathan, P., Rapino, F., Close, P., Bukczynska, P., Scharmann, K., Takizawa, I., Risbridger, G. P., Selth, L. A., Leidel, S. A., Lin, Q. & 3 others, Topisirovic, I., Larsson, O. & Furic, L., 2 Dec 2019, In : The EMBO Journal. 38, 23, 19 p., e101323.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)
2018

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

Schumacher, F. R., Al Olama, A. A., Berndt, S. I., Benlloch, S., Ahmed, M., Saunders, E. J., Dadaev, T., Leongamornlert, D., Anokian, E., Cieza-Borrella, C., Goh, C., Brook, M. N., Sheng, X., Fachal, L., Dennis, J., Tyrer, J., Muir, K., Lophatananon, A., Stevens, V. L., Gapstur, S. M. & 167 others, Carter, B. D., Tangen, C. M., Goodman, P. J., Thompson, I. M., Batra, J., Chambers, S., Moya, L., Clements, J., Horvath, L., Tilley, W., Risbridger, G. P., Gronberg, H., Aly, M., Nordström, T., Pharoah, P., Pashayan, N., Schleutker, J., Tammela, T. L. J., Sipeky, C., Auvinen, A., Albanes, D., Weinstein, S., Wolk, A., Håkansson, N., West, C. M. L., Dunning, A. M., Burnet, N., Mucci, L. A., Giovannucci, E., Andriole, G. L., Cussenot, O., Cancel-Tassin, G., Koutros, S., Beane Freeman, L. E., Sorensen, K. D., Orntoft, T. F., Borre, M., Maehle, L., Grindedal, E. M., Neal, D. E., Donovan, J. L., Hamdy, F. C., Martin, R. M., Travis, R. C., Key, T. J., Hamilton, R. J., Fleshner, N. E., Finelli, A., Ingles, S. A., Stern, M. C., Rosenstein, B. S., Kerns, S. L., Ostrer, H., Lu, Y. J., Zhang, H. W., Feng, N., Mao, X., Guo, X., Wang, G., Sun, Z., Giles, G. G., Southey, M. C., MacInnis, R. J., Fitzgerald, L. M., Kibel, A. S., Drake, B. F., Vega, A., Gómez-Caamaño, A., Szulkin, R., Eklund, M., Kogevinas, M., Llorca, J., Castaño-Vinyals, G., Penney, K. L., Stampfer, M., Park, J. Y., Sellers, T. A., Lin, H. Y., Stanford, J. L., Cybulski, C., Wokolorczyk, D., Lubinski, J., Ostrander, E. A., Geybels, M. S., Nordestgaard, B. G., Nielsen, S. F., Weischer, M., Bisbjerg, R., Røder, M. A., Iversen, P., Brenner, H., Cuk, K., Holleczek, B., Maier, C., Luedeke, M., Schnoeller, T., Kim, J., Logothetis, C. J., John, E. M., Teixeira, M. R., Paulo, P., Cardoso, M., Neuhausen, S. L., Steele, L., Ding, Y. C., De Ruyck, K., De Meerleer, G., Ost, P., Razack, A., Lim, J., Teo, S. H., Lin, D. W., Newcomb, L. F., Lessel, D., Gamulin, M., Kulis, T., Kaneva, R., Usmani, N., Singhal, S., Slavov, C., Mitev, V., Parliament, M., Claessens, F., Joniau, S., Van Den Broeck, T., Larkin, S., Townsend, P. A., Aukim-Hastie, C., Dominguez, M. G., Castelao, J. E., Martinez, M. E., Roobol, M. J., Jenster, G., Van Schaik, R. H. N., Menegaux, F., Truong, T., Koudou, Y. A., Xu, J., Khaw, K. T., Cannon-Albright, L., Pandha, H., Michael, A., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., Lindstrom, S., Turman, C., Ma, J., Hunter, D. J., Riboli, E., Siddiq, A., Canzian, F., Kolonel, L. N., Le Marchand, L., Hoover, R. N., Machiela, M. J., Cui, Z., Kraft, P., Amos, C. I., Conti, D. V., Easton, D. F., Wiklund, F., Chanock, S. J., Henderson, B. E., Kote-Jarai, Z., Haiman, C. A. & Eeles, R. A., 1 Jul 2018, In : Nature Genetics. 50, 7, p. 928-936 9 p.

Research output: Contribution to journalArticleResearchpeer-review

105 Citations (Scopus)

Elevated seminal plasma estradiol and epigenetic inactivation of ESR1 and ESR2 is associated with CP/CPPS

Nesheim, N., Ellem, S., Dansranjavin, T., Hagenkötter, C., Berg, E., Schambeck, R., Schuppe, H. C., Pilatz, A., Risbridger, G., Weidner, W., Wagenlehner, F. & Schagdarsurengin, U., 13 Apr 2018, In : Oncotarget. 9, 28, p. 19623-19639 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2 Citations (Scopus)

Enduring epigenetic landmarks define the cancer microenvironment

Pidsley, R., Lawrence, M. G., Zotenko, E., Niranjan, B., Statham, A., Song, J., Chabanon, R. M., Qu, W., Wang, H., Richards, M., Nair, S. S., Armstrong, N., Nim, H. T., Papargiris, M., Balanathan, P., French, H., Peters, T., Norden, S., Ryan, A., Pedersen, J. & 9 others, Kench, J. G., Daly, R. J., Horvath, L., Stricker, P., Frydenberg, M., Taylor, R. A., Stirzaker, C., Risbridger, G. P. & Clark, S. J., 1 May 2018, In : Genome Research. 28, 5, p. 625-638 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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24 Citations (Scopus)

Estrogen receptor subtypes dictate the proliferative nature of the mammary gland

Dall, G. V., Hawthorne, S., Seyed-Razavi, Y., Vieusseux, J., Wu, W., Gustafsson, J. A., Byrne, D., Murphy, L., Risbridger, G. P. & Britt, K. L., 1 Jun 2018, In : Journal of Endocrinology. 237, 3, p. 323-336 14 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants

Dadaev, T., Saunders, E. J., Newcombe, P. J., Anokian, E., Leongamornlert, D. A., Brook, M. N., Cieza-Borrella, C., Mijuskovic, M., Wakerell, S., Olama, A. A. A., Schumacher, F. R., Berndt, S. I., Benlloch, S., Ahmed, M., Goh, C., Sheng, X., Zhang, Z., Muir, K., Govindasami, K., Lophatananon, A. & 172 others, Stevens, V. L., Gapstur, S. M., Carter, B. D., Tangen, C. M., Goodman, P., Thompson, I. M., Batra, J., Chambers, S., Moya, L., Clements, J., Horvath, L., Tilley, W., Risbridger, G., Gronberg, H., Aly, M., Nordström, T., Pharoah, P., Pashayan, N., Schleutker, J., Tammela, T. L. J., Sipeky, C., Auvinen, A., Albanes, D., Weinstein, S., Wolk, A., Hakansson, N., West, C., Dunning, A. M., Burnet, N., Mucci, L., Giovannucci, E., Andriole, G., Cussenot, O., Cancel-Tassin, G., Koutros, S., Freeman, L. E. B., Sorensen, K. D., Orntoft, T. F., Borre, M., Maehle, L., Grindedal, E. M., Neal, D. E., Donovan, J. L., Hamdy, F. C., Martin, R. M., Travis, R. C., Key, T. J., Hamilton, R. J., Fleshner, N. E., Finelli, A., Ingles, S. A., Stern, M. C., Rosenstein, B., Kerns, S., Ostrer, H., Lu, Y. J., Zhang, H. W., Feng, N., Mao, X., Guo, X., Wang, G., Sun, Z., Giles, G. G., Southey, M. C., MacInnis, R. J., Fitzgerald, L. M., Kibel, A. S., Drake, B. F., Vega, A., Gómez-Caamaño, A., Fachal, L., Szulkin, R., Eklund, M., Kogevinas, M., Llorca, J., Castaño-Vinyals, G., Penney, K. L., Stampfer, M., Park, J. Y., Sellers, T. A., Lin, H. Y., Stanford, J. L., Cybulski, C., Wokolorczyk, D., Lubinski, J., Ostrander, E. A., Geybels, M. S., Nordestgaard, B. G., Nielsen, S. F., Weisher, M., Bisbjerg, R., Røder, M. A., Iversen, P., Brenner, H., Cuk, K., Holleczek, B., Maier, C., Luedeke, M., Schnoeller, T., Kim, J., Logothetis, C. J., John, E. M., Teixeira, M. R., Paulo, P., Cardoso, M., Neuhausen, S. L., Steele, L., Ding, Y. C., De Ruyck, K., De Meerleer, G., Ost, P., Razack, A., Lim, J., Teo, S. H., Lin, D. W., Newcomb, L. F., Lessel, D., Gamulin, M., Kulis, T., Kaneva, R., Usmani, N., Slavov, C., Mitev, V., Parliament, M., Singhal, S., Claessens, F., Joniau, S., Van Den Broeck, T., Larkin, S., Townsend, P. A., Aukim-Hastie, C., Gago-Dominguez, M., Castelao, J. E., Martinez, M. E., Roobol, M. J., Jenster, G., Van Schaik, R. H. N., Menegaux, F., Truong, T., Koudou, Y. A., Xu, J., Khaw, K. T., Cannon-Albright, L., Pandha, H., Michael, A., Kierzek, A., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., Lindstrom, S., Turman, C., Ma, J., Hunter, D. J., Riboli, E., Siddiq, A., Canzian, F., Kolonel, L. N., Le Marchand, L., Hoover, R. N., Machiela, M. J., Kraft, P., Cook, M., Freedman, M. L., Wiklund, F., Chanock, S. J., Henderson, B. E., Easton, D. F., Haiman, C. A., Eeles, R. A., Conti, D. V., Kote-Jarai, Z. & The PRACTICAL consortium, 1 Dec 2018, In : Nature Communications. 9, 1, 19 p., 2256.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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24 Citations (Scopus)

Germline variation at 8q24 and prostate cancer risk in men of European ancestry

Matejcic, M., Saunders, E. J., Dadaev, T., Brook, M. N., Wang, K., Sheng, X., Al Olama, A. A., Schumacher, F., Ingles, S. A., Govindasami, K., Benlloch, S., Berndt, S., Albanes, D., Koutros, S., Muir, K., Stevens, V. L., Gapstur, S. M., Tangen, C. M., Batra, J., Clements, J. & 7 others, PRACTICAL Consortium, Giles, G., Milne, R. L., Taylor, R., Papargiris, M. M., Risbridger, G. & Southey, M. C., 5 Nov 2018, In : Nature Communications. 9, 11 p., 382.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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10 Citations (Scopus)

Humanization of the prostate microenvironment reduces homing of PC3 prostate cancer cells to human tissue-engineered bone

McGovern, J. A., Shafiee, A., Wagner, F., Lahr, C. A., Landgraf, M., Meinert, C., Williams, E. D., Russell, P. J., Clements, J. A., Loessner, D., Holzapfel, B. M., Risbridger, G. P. & Hutmacher, D. W., 13 Nov 2018, In : Cancers. 10, 11, 15 p., 438.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Intraductal carcinoma of the prostate can evade androgen deprivation, with emergence of castrate-tolerant cells

Porter, L. H., Hashimoto, K., Lawrence, M. G., Pezaro, C., Clouston, D., Wang, H., Papargiris, M., Thorne, H., Li, J., Investigators, K., Ryan, A., Norden, S., Moon, D., Bolton, D. M., Sengupta, S., Frydenberg, M., Murphy, D. G., Risbridger, G. P. & Taylor, R. A., 1 Jun 2018, In : BJU International. 121, 6, p. 971-978 8 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Movember GAP1 PDX project: An international collection of serially transplantable prostate cancer patient-derived xenograft (PDX) models

Navone, N. M., van Weerden, W. M., Vessella, R. L., Williams, E. D., Wang, Y., Isaacs, J. T., Nguyen, H. M., Culig, Z., van der Pluijm, G., Rentsch, C. A., Marques, R. B., de Ridder, C. M. A., Bubendorf, L., Thalmann, G. N., Brennen, W. N., Santer, F. R., Moser, P. L., Shepherd, P., Efstathiou, E., Xue, H. & 9 others, Lin, D., Collins, A., Maitland, N., Buzza, M., Kouspou, M., Achtman, A., Taylor, R. A., Risbridger, G. & Corey, E., 1 Dec 2018, In : Prostate. 78, 16, p. 1262-1282 21 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Novel imaging of the prostate reveals spontaneous gland contraction and excretory duct quiescence together with different drug effects

Kügler, R., Mietens, A., Seidensticker, M., Tasch, S., Wagenlehner, F. M., Kaschtanow, A., Tjahjono, Y., Tomczyk, C. U., Beyer, D., Risbridger, G. P., Exintaris, B., Ellem, S. J. & Middendorff, R., 1 Mar 2018, In : The FASEB Journal. 32, 3, p. 1130-1138 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy

Lawrence, M. G., Obinata, D., Sandhu, S., Selth, L. A., Wong, S. Q., Porter, L. H., Lister, N., Pook, D., Pezaro, C. J., Goode, D. L., Rebello, R. J., Clark, A. K., Papargiris, M., Van Gramberg, J., Hanson, A. R., Banks, P., Wang, H., Niranjan, B., Keerthikumar, S., Hedwards, S. & 32 others, Huglo, A., Yang, R., Henzler, C., Li, Y., Lopez-Campos, F., Castro, E., Toivanen, R., Azad, A., Bolton, D., Goad, J., Grummet, J., Harewood, L., Kourambas, J., Lawrentschuk, N., Moon, D., Murphy, D. G., Sengupta, S., Snow, R., Thorne, H., Mitchell, C., Pedersen, J., Clouston, D., Norden, S., Ryan, A., Dehm, S. M., Tilley, W. D., Pearson, R. B., Hannan, R. D., Frydenberg, M., Furic, L., Taylor, R. A. & Risbridger, G. P., 1 Nov 2018, In : European Urology. 74, 5, p. 562-572 11 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)
Open Access
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16 Citations (Scopus)

Role of activin C in normal ovaries and granulosa cell tumours of mice and humans

Reader, K. L., Marino, F. E., Nicholson, H. D., Risbridger, G. P. & Gold, E. J., 1 Jan 2018, In : Reproduction, Fertility and Development. 30, 7, p. 958-968 11 p., RD17250.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2 Citations (Scopus)
2017

Age Related Differences in Responsiveness to Sildenafil and Tamsulosin are due to Myogenic Smooth Muscle Tone in the Human Prostate

Lee, S. N., Chakrabarty, B., Wittmer, B., Papargiris, M., Ryan, A., Frydenberg, M., Frydenberg, M., Lawrentschuk, N., Middendorff, R., Risbridger, G. P., Ellem, S. J. & Exintaris, B., 1 Dec 2017, In : Scientific Reports. 7, 1, 9 p., 10150.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

A rare castration-resistant progenitor cell population is highly enriched in Pten-null prostate tumours

Sackmann Sala, L., Boutillon, F., Menara, G., De Goyon-Pélard, A., Leprévost, M., Codzamanian, J., Lister, N., Pencik, J., Clark, A., Cagnard, N., Bole-Feysot, C., Moriggl, R., Risbridger, G. P., Taylor, R. A., Kenner, L., Guidotti, J. E. & Goffin, V., Sep 2017, In : Journal of Pathology. 243, 1, p. 51-64 14 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories

Taylor, R. A., Fraser, M., Livingstone, J., Espiritu, S. M. G., Thorne, H., Huang, V., Lo, W., Shiah, Y-J., Yamaguchi, T. N., Sliwinski, A., Horsburgh, S., Meng, A., Heisler, L. E., Yu, N., Yousif, F., Papargiris, M., Lawrence, M. G., Timms, L., Murphy, D. G., Frydenberg, M. & 8 others, Hopkins, J. F., Bolton, D., Clouston, D., McPherson, J. D., Van Der Kwast, T., Boutros, P. C., Risbridger, G. P. & Bristow, R. G., 9 Jan 2017, In : Nature Communications. 8, 10 p., 13671.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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80 Citations (Scopus)

Kallikrein-related peptidase 4 induces cancer-associated fibroblast features in prostate-derived stromal cells

Kryza, T., Silva, L. M., Bock, N., Fuhrman-Luck, R. A., Stephens, C. R., Gao, J., Samaratunga, H., Australian Prostate Cancer BioResource, Lawrence, M. G., Hooper, J. D., Dong, Y., Risbridger, G. P. & Clements, J. A., 1 Oct 2017, In : Molecular Oncology. 11, 10, p. 1307-1329 23 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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5 Citations (Scopus)

Mysterious inhibitory cell regulator investigated and found likely to be secretogranin II related

Hart, J. E., Clarke, I. J., Risbridger, G. P., Ferneyhough, B. & Vega-Hernández, M., 13 Oct 2017, In : PeerJ. 2017, 10, 42 p., e3833.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Over-expression of Activin-βC is associated with murine and human prostate disease

Ottley, E. C., Reader, K. L., Lee, K., Marino, F. E., Nicholson, H. D., Risbridger, G. P. & Gold, E., Apr 2017, In : Hormones and Cancer. 8, 2, p. 100-107 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Regional localization of activin-βA, activin-βC, follistatin, proliferation, and apoptosis in adult and developing mouse prostate ducts

Gold, E., Zellhuber-McMillan, S., Risbridger, G. & Marino, F. E., 1 Jan 2017, In : Gene Expression Patterns. 23-24, p. 70-79 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

SCA-1 labels a subset of estrogen-responsive bipotential repopulating cells within the CD24+ CD49fhi mammary stem cell-enriched compartment

Dall, G. V., Vieusseux, J. L., Korach, K. S., Arao, Y., Hewitt, S. C., Hamilton, K. J., Dzierzak, E., Boon, W. C., Simpson, E. R., Ramsay, R. G., Stein, T., Morris, J. S., Anderson, R. L., Risbridger, G. P. & Britt, K. L., 14 Feb 2017, In : Stem Cell Reports. 8, 2, p. 417-431 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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13 Citations (Scopus)

Systematic Review Links the Prevalence of Intraductal Carcinoma of the Prostate to Prostate Cancer Risk Categories

Porter, L. H., Lawrence, M. G., Ilic, D., Clouston, D., Bolton, D. M., Frydenberg, M., Murphy, D. G., Pezaro, C., Risbridger, G. P. & Taylor, R. A., Oct 2017, In : European Urology. 72, 4, p. 492-495 4 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

The Evolving Narrative of DNA Repair Gene Defects: Distinguishing Indolent from Lethal Prostate Cancer

Murphy, D. G., Risbridger, G. P., Bristow, R. G. & Sandhu, S., May 2017, In : European Urology. 71, 5, p. 748-749 2 p.

Research output: Contribution to journalArticleOtherpeer-review

6 Citations (Scopus)

The prognostic value of stromal FK506-binding protein 1 and androgen receptor in prostate cancer outcome

Leach, D. A., Trotta, A. P., Need, E. F., Risbridger, G. P., Taylor, R. A. & Buchanan, G., 1 Feb 2017, In : Prostate. 77, 2, p. 185-195 11 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)
2016

A single nucleotide polymorphism genotyping platform for the authentication of patient derived xenografts

El-Hoss, J., Jing, D., Evans, K., Toscan, C., Xie, J., Lee, H., Taylor, R. A., Lawrence, M. G., Risbridger, G. P., MacKenzie, K. L., Sutton, R. & Lock, R. B., 9 Aug 2016, In : Oncotarget. 7, 37, p. 60475-60490 16 p.

Research output: Contribution to journalArticleResearchpeer-review

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7 Citations (Scopus)

Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling

Pidsley, R., Zotenko, E., Peters, T. J., Lawrence, M. G., Risbridger, G. P., Molloy, P., Van Djik, S., Muhlhausler, B., Stirzaker, C. & Clark, S. J., 7 Oct 2016, In : Genome Biology. 17, 1, 17 p., 208.

Research output: Contribution to journalArticleResearchpeer-review

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212 Citations (Scopus)

Mouse hypospadias: A critical examination and definition

Sinclair, A. W., Cao, M., Shen, J., Cooke, P., Risbridger, G., Baskin, L. & Cunha, G. R., Dec 2016, In : Differentiation. 92, 5, p. 306-317 12 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Obesity does not promote tumorigenesis of localized patient-derived prostate cancer xenografts

Lo, J. C. Y., Clark, A. K., Ascui, N., Frydenberg, M., Risbridger, G. P., Taylor, R. A. & Watt, M. J., 23 Jun 2016, In : Oncotarget. 7, 30, p. 47650-47662 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
9 Citations (Scopus)

Patient-derived prostate cancer: From basic science to the clinic

Risbridger, G. P. & Taylor, R. A., Aug 2016, In : Hormones and Cancer. 7, 4, p. 236-240 5 p.

Research output: Contribution to journalArticleOtherpeer-review

5 Citations (Scopus)

Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort

Bonilla, C., Lewis, S. J., Martin, R. M., Donovan, J. L., Hamdy, F. C., Neal, D. E., Eeles, R. A., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Wiklund, F., Gronberg, H., Haiman, C. A., Schleutker, J., Nordestgaard, B. G., Travis, R. C., Pashayan, N. & 17 others, Khaw, K-T., Stanford, J. L., Blot, W. J., Thibodeau, S. N., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J. H., Kaneva, R. P., Batra, J., Teixeira, M. R., Pandha, H. S., Lathrop, M. G., Smith, G. D. & The PRACTICAL consortium, 2016, In : BMC Medicine. 14, 1, 11 p., 66.

Research output: Contribution to journalArticleResearchpeer-review

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18 Citations (Scopus)

Searching for candidate genes in familial BRCAX mutation carriers with prostate cancer

Hunter, S. M., Rowley, S. M., Clouston, D., KCon Fab Investigators, Li, J., Lupat, R., Krishnananthan, N., Risbridger, G., Taylor, R., Bolton, D., Campbell, I. G. & Thorne, H., Mar 2016, In : Urologic Oncology: Seminars and Original Investigations. 34, 3, p. 120.e9–120.e16 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

The dual inhibition of RNA Pol I transcription and PIM kinase as a new therapeutic approach to treat advanced prostate cancer

Rebello, R. J., Kusnadi, E., Cameron, D. P., Pearson, H. B., Lesmana, A., Devlin, J. R., Drygin, D., Clark, A. K., Porter, L., Pedersen, J., Sandhu, S., Risbridger, G. P., Pearson, R. B., Hannan, R. D. & Furic, L., 15 Nov 2016, In : Clinical Cancer Research. 22, 22, p. 5539-5552 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
29 Citations (Scopus)
2015

Activin-{beta}C modulates cachexia by repressing the ubiquitin-proteasome and autophagic degradation pathways

Marino, F. E., Risbridger, G. P. & Gold, E. J., 2015, In : Journal of Cachexia, Sarcopenia and Muscle. 6, 4, p. 365 - 380 16 p.

Research output: Contribution to journalArticleResearchpeer-review

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15 Citations (Scopus)

Activin-betaC modulates gonadal, but not adrenal tumorigenesis in the inhibin deficient mice

Marino, F. E., Risbridger, G. P. & Gold, E. J., 2015, In : Molecular and Cellular Endocrinology. 409, p. 41 - 50 10 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

A large-scale analysis of genetic variants within putative miRNA binding sites in prostate cancer

Stegeman, S., Amankwah, E., Klein, K., O’Mara, T. A., Kim, D., Lin, H-Y. L., Permuth-Wey, J., Sellers, T. A., Srinivasan, S., Eeles, R. A., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Wiklund, F., Gronberg, H., Haiman, C. A., Schleutker, J. & 2 others, PRACTICAL Consortium & Australian Prostate Cancer BioResource, 1 Apr 2015, In : Cancer Discovery. 5, 4, p. 368-379 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
32 Citations (Scopus)

Convergence of regenerative medicine and synthetic biology to develop standardized and validated models of human diseases with clinical relevance

Hutmacher, D. W., Holzapfel, B. M., De-Juan-Pardo, E. M., Pereira, B. A., Ellem, S. J., Loessner, D. & Risbridger, G. P., 2015, In : Current Opinion in Biotechnology. 35, p. 127 - 132 6 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Current understanding of hypospadias: relevance of animal models

Cunha, G. R., Sinclair, A., Risbridger, G. P., Hutson, J. & Baskin, L. S., 2015, In : Nature Reviews Urology. 12, 5, p. 271 - 280 10 p.

Research output: Contribution to journalArticleResearchpeer-review

49 Citations (Scopus)

Establishment of primary patient-derived xenografts of palliative TURP specimens to study castrate-resistant prostate cancer

Lawrence, M. G., Pook, D. W., Wang, H., Porter, L. H., Frydenberg, M., Kourambas, J., Appu, S., Poole, C., Beardsley, E. K., Ryan, A. J., Norden, S., Papargiris, M., Risbridger, G. P. & Taylor, R. A., 2015, In : Prostate. 75, 13, p. 1475 - 1483 9 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity

Takizawa, I., Lawrence, M. G., Balanathan, P., Rebello, R., Pearson, H. B., Garg, E., Pedersen, J. S., Pouliot, N., Nadon, R., Watt, M. J., Taylor, R. A., Humbert, P. O., Topisirovic, I., Larsson, O., Risbridger, G. P. & Furic, L., 2015, In : Oncotarget. 6, 2, p. 604 - 616 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
21 Citations (Scopus)