PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells

Flosbach, M., Oberle, S. G., Scherer, S., Zecha, J., von Hoesslin, M., Wiede, F., Chennupati, V., Cullen, J. G., List, M., Pauling, J. K., Baumbach, J., Kuster, B., Tiganis, T. & Zehn, D., 28 Jul 2020, In: Cell Reports. 32, 4, 16 p., 107957.

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PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours

Wiede, F., Lu, K-H., Du, X., Liang, S., Hochheiser, K., Dodd, G. T., Goh, P. K., Kearney, C., Meyran, D., Beavis, P. A., Henderson, M. A., Park, S. L., Waithman, J., Zhang, S., Zhang, Z. Y., Oliaro, J., Gebhardt, T., Darcy, P. K. & Tiganis, T., 15 Jan 2020, In: The EMBO Journal. 39, 2, 26 p., e103637.

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A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1

Le Nours, J., Gherardin, N. A., Ramarathinam, S. H., Awad, W., Wiede, F., Gully, B. S., Khandokar, Y., Praveena, T., Wubben, J. M., Sandow, J. J., Webb, A. I., von Borstel, A., Rice, M. T., Redmond, S. J., Seneviratna, R., Sandoval-Romero, M. L., Li, S., Souter, M. N. T., Eckle, S. B. G., Corbett, A. J. & 15 others, Reid, H. H., Liu, L., Fairlie, D. P., Giles, E. M., Westall, G. P., Tothill, R. W., Davey, M. S., Berry, R., Tiganis, T., McCluskey, J., Pellicci, D. G., Purcell, A. W., Uldrich, A. P., Godfrey, D. I. & Rossjohn, J., 20 Dec 2019, In: Science. 366, 6472, p. 1522-1527 6 p.

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Activation of naïve CD4 ⁺ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4 ⁺ T cells

Twohig, J. P., Cardus Figueras, A., Andrews, R., Wiede, F., Cossins, B. C., Derrac Soria, A., Lewis, M. J., Townsend, M. J., Millrine, D., Li, J., Hill, D. G., Uceda Fernandez, J., Liu, X., Szomolay, B., Pepper, C. J., Taylor, P. R., Pitzalis, C., Tiganis, T., Williams, N. M., Jones, G. W. & 1 others, Jones, S. A., 1 Apr 2019, In: Nature Immunology. 20, 4, p. 458-470 13 p.

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Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity

Svensson, M. N., Doody, K. M., Schmiedel, B. J., Bhattacharyya, S., Panwar, B., Wiede, F., Yang, S., Santelli, E., Wu, D. J., Sacchetti, C., Gujar, R., Seumois, G., Kiosses, W. B., Aubry, I., Kim, G., Mydel, P., Sakaguchi, S., Kronenberg, M., Tiganis, T., Tremblay, M. L. & 3 others, Ay, F., Vijayanand, P. & Bottini, N., 1 Mar 2019, In: Journal of Clinical Investigation. 129, 3, p. 1193-1210 18 p.

Research output: Contribution to journal › Article › Research › peer-review