Florian Wiede

Dr

20092019
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Personal profile

Biography

Florian works in the Faculty of Medicine, Nursing and Health Sciences at Monash University as a Research Fellow.

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Projects 2016 2018

Research Output 2009 2019

A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1

Le Nours, J., Gherardin, N. A., Ramarathinam, S. H., Awad, W., Wiede, F., Gully, B. S., Khandokar, Y., Praveena, T., Wubben, J. M., Sandow, J. J., Webb, A. I., von Borstel, A., Rice, M. T., Redmond, S. J., Seneviratna, R., Sandoval-Romero, M. L., Li, S., Souter, M. N. T., Eckle, S. B. G., Corbett, A. J. & 15 others, Reid, H. H., Liu, L., Fairlie, D. P., Giles, E. M., Westall, G. P., Tothill, R. W., Davey, M. S., Berry, R., Tiganis, T., McCluskey, J., Pellicci, D. G., Purcell, A. W., Uldrich, A. P., Godfrey, D. I. & Rossjohn, J., 20 Dec 2019, In : Science. 366, 6472, p. 1522-1527 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Activation of naïve CD4 + T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4 + T cells

Twohig, J. P., Cardus Figueras, A., Andrews, R., Wiede, F., Cossins, B. C., Derrac Soria, A., Lewis, M. J., Townsend, M. J., Millrine, D., Li, J., Hill, D. G., Uceda Fernandez, J., Liu, X., Szomolay, B., Pepper, C. J., Taylor, P. R., Pitzalis, C., Tiganis, T., Williams, N. M., Jones, G. W. & 1 others, Jones, S. A., 1 Apr 2019, In : Nature Immunology. 20, 4, p. 458-470 13 p.

Research output: Contribution to journalArticleResearchpeer-review

PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours

Wiede, F., Lu, K-H., Du, X., Liang, S., Hochheiser, K., Dodd, G. T., Goh, P. K., Kearney, C., Meyran, D., Beavis, P. A., Henderson, M. A., Park, S. L., Waithman, J., Zhang, S., Zhang, Z. Y., Oliaro, J., Gebhardt, T., Darcy, P. K. & Tiganis, T., 2019, (Accepted/In press) In : EMBO Journal. 26 p., e103637.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity

Svensson, M. N., Doody, K. M., Schmiedel, B. J., Bhattacharyya, S., Panwar, B., Wiede, F., Yang, S., Santelli, E., Wu, D. J., Sacchetti, C., Gujar, R., Seumois, G., Kiosses, W. B., Aubry, I., Kim, G., Mydel, P., Sakaguchi, S., Kronenberg, M., Tiganis, T., Tremblay, M. L. & 3 others, Ay, F., Vijayanand, P. & Bottini, N., 1 Mar 2019, In : The Journal of clinical investigation. 129, 3, p. 1193-1210 18 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

T-cell–specific PTPN2 deficiency in NOD mice accelerates the development of type 1 diabetes and autoimmune comorbidities

Wiede, F., Brodnicki, T. C., Goh, P. K., Leong, Y. A., Jones, G. W., Yu, D., Baxter, A. G., Jones, S. A., Kay, T. W. H. & Tiganis, T., 1 Jun 2019, In : Diabetes. 68, 6, p. 1251-1266 16 p.

Research output: Contribution to journalArticleResearchpeer-review