Research Output per year
Personal profile
Biography
Dr. Brown completed her PhD in 2013 at the University of Melbourne. During her PhD, Dr. Brown studied the molecular mechanisms underpinning anaemia, including iron deficiency anaemia and beta thalassaemia, the most common causes of anaemia. She then worked as a Research Fellow at Memorial Sloan Kettering Cancer Center in New York, USA, where she studied pathways regulating chemotherapy resistance in acute meloid leukaemia (AML). In 2017, she moved to the Australian Ceneter for Blood Diseases, Monash University based at the Alfred Hospital. Here she is investigating improved targeted therapeutic strategies in AML.
Keywords
- Acute myeloid leukaemia
- resistance dynamics
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Research Output 2013 2018
- 9 Article
Bone marrow transplantation corrects haemolytic anaemia in a novel ENU mutagenesis mouse model of TPI deficiency
Conway, A., Brown, F. C., Hortle, E. J., Burgio, G., Foote, S. J., Morton, C. J., Jane, S. M. & Curtis, D. J. 2018 (Accepted/In press) In : Disease Models & Mechanisms. p. 1-8 8 p.Research output: Contribution to journal › Article
Open Access
Peptidomimetic blockade of MYB in acute myeloid leukemia
Ramaswamy, K., Forbes, L., Minuesa, G., Gindin, T., Brown, F., Kharas, M. G., Krivtsov, A. V., Armstrong, S. A., Still, E., De Stanchina, E., Knoechel, B., Koche, R. & Kentsis, A. 1 Dec 2018 In : Nature Communications. 9, 1, 110Research output: Contribution to journal › Article
A mouse model of hereditary coproporphyria identified in an ENU mutagenesis screen
Conway, A. J., Brown, F. C., Fullinfaw, R. O., Kile, B. T., Jane, S. M. & Curtis, D. J. 1 Aug 2017 In : Disease Models & Mechanisms. 10, 8, p. 1005-1013 9 p.Research output: Contribution to journal › Article
Open Access
File
Genomics of primary chemoresistance and remission induction failure in paediatric and adult acute myeloid leukaemia
Brown, F. C., Cifani, P., Drill, E., He, J., Still, E., Zhong, S., Balasubramanian, S., Pavlick, D., Yilmazel, B., Knapp, K. M., Alonzo, T. A., Meshinchi, S., Stone, R. M., Kornblau, S. M., Marcucci, G., Gamis, A. S., Byrd, J. C., Gonen, M., Levine, R. L. & Kentsis, A. 1 Jan 2017 In : British Journal of Haematology. 176, 1, p. 86-91 6 p.Research output: Contribution to journal › Article
Loss of Dynamin 2 GTPase function results in microcytic anaemia
Brown, F., Collett, M., Tremblay, C. S., Rank, G., De Camilli, P., Booth, C. J., Bitoun, M., Robinson, P. J., Kile, B. T., Jane, S. M. & Curtis, D. J. Sep 2017 In : British Journal of Haematology. 178, 4, p. 616 - 628 13 p.Research output: Contribution to journal › Article