Research Output per year
Personal profile
Biography
Dr. Brown completed her PhD in 2013 at the University of Melbourne. During her PhD, Dr. Brown studied the molecular mechanisms underpinning anaemia, including iron deficiency anaemia and beta thalassaemia, the most common causes of anaemia. She then worked as a Research Fellow at Memorial Sloan Kettering Cancer Center in New York, USA, where she studied pathways regulating chemotherapy resistance in acute meloid leukaemia (AML). In 2017, she moved to the Australian Ceneter for Blood Diseases, Monash University based at the Alfred Hospital. Here she is investigating improved targeted therapeutic strategies in AML.
Keywords
- Acute myeloid leukaemia
- resistance dynamics
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Research Output 2013 2018
- 11 Article
Bone marrow transplantation corrects haemolytic anaemia in a novel ENU mutagenesis mouse model of TPI deficiency
Conway, A., Brown, F. C., Hortle, E. J., Burgio, G., Foote, S. J., Morton, C. J., Jane, S. M. & Curtis, D. J., 21 May 2018, In : Disease Models & Mechanisms. 11, 5, 8 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Characterization of Tfrc-mutant mice with microcytic phenotypes
Conway, A. J., Brown, F. C., Rank, G., Kile, B. T., Morton, C. J., Jane, S. M. & Curtis, D. J., 14 Aug 2018, In : Blood Advances. 2, 5, p. 1914-1922 9 p.Research output: Contribution to journal › Article › Research › peer-review
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia
Brown, F. C., Still, E., Koche, R. P., Yim, C. Y., Takao, S., Cifani, P., Reed, C., Gunasekera, S., Ficarro, S. B., Romanienko, P., Mark, W., McCarthy, C., de Stanchina, E., Gonen, M., Seshan, V., Bhola, P., O’Donnell, C., Spitzer, B., Stutzke, C., Lavallée, V. P. & 12 others, 1 Apr 2018, In : Cancer Discovery. 8, 4, p. 478-497 20 p.Research output: Contribution to journal › Article › Research › peer-review
Peptidomimetic blockade of MYB in acute myeloid leukemia
Ramaswamy, K., Forbes, L., Minuesa, G., Gindin, T., Brown, F., Kharas, M. G., Krivtsov, A. V., Armstrong, S. A., Still, E., De Stanchina, E., Knoechel, B., Koche, R. & Kentsis, A., 1 Dec 2018, In : Nature Communications. 9, 1, 13 p., 110.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
A mouse model of hereditary coproporphyria identified in an ENU mutagenesis screen
Conway, A. J., Brown, F. C., Fullinfaw, R. O., Kile, B. T., Jane, S. M. & Curtis, D. J., 1 Aug 2017, In : Disease Models & Mechanisms. 10, 8, p. 1005-1013 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File