• Australian Centre for Blood Diseases Central Clinical School, Monash University Level 1, Walkway via The Alfred Centre, 99 Commercial Road, Melbourne 3004

    Australia

20132020

Research output per year

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Personal profile

Biography

Dr. Brown completed her PhD in 2013 at the University of Melbourne. During her PhD, Dr. Brown studied the molecular mechanisms underpinning anaemia, including iron deficiency anaemia and beta thalassaemia, the most common causes of anaemia. She then worked as a Research Fellow at Memorial Sloan Kettering Cancer Center in New York, USA, where she studied pathways regulating chemotherapy resistance in acute meloid leukaemia (AML). In 2017, she moved to the Australian Ceneter for Blood Diseases, Monash University based at the Alfred Hospital. Here she is investigating improved targeted therapeutic strategies in AML. 

Research area keywords

  • Acute myeloid leukaemia
  • resistance dynamics

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Projects

Research Output

Author Correction: KCC1 Activation protects Mice from the Development of Experimental Cerebral Malaria (Scientific Reports, (2019), 9, 1, (6356), 10.1038/s41598-019-42782-x)

Hortle, E., Starrs, L., Brown, F. C., Jane, S. M., Curtis, D. J., McMorran, B. J., Foote, S. J. & Burgio, G., 1 Dec 2020, In : Scientific Reports. 10, 1, 1 p., 2303.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access

BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals

Srivastava, R., Cao, Z., Nedeva, C., Naim, S., Bachmann, D., Rabachini, T., Gangoda, L., Shahi, S., Glab, J., Menassa, J., Osellame, L., Nelson, T., Fernandez-Marrero, Y., Brown, F., Wei, A., Ke, F., O'Reilly, L., Doerflinger, M., Allison, C., Kueh, A. & 5 others, Ramsay, R., Smith, B. J., Mathivanan, S., Kaufmann, T. & Puthalakath, H., 30 Jul 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 31, p. 15469-15474 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
3 Citations (Scopus)

KCC1 Activation protects Mice from the Development of Experimental Cerebral Malaria

Hortle, E., Starrs, L., Brown, F. C., Jane, S. M., Curtis, D. J., McMorran, B. J., Foote, S. J. & Burgio, G., 1 Dec 2019, In : Scientific Reports. 9, 1, 11 p., 6356.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Bone marrow transplantation corrects haemolytic anaemia in a novel ENU mutagenesis mouse model of TPI deficiency

Conway, A., Brown, F. C., Hortle, E. J., Burgio, G., Foote, S. J., Morton, C. J., Jane, S. M. & Curtis, D. J., 21 May 2018, In : Disease Models and Mechanisms. 11, 5, 8 p., dmm034678.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
4 Citations (Scopus)

Characterization of Tfrc-mutant mice with microcytic phenotypes

Conway, A. J., Brown, F. C., Rank, G., Kile, B. T., Morton, C. J., Jane, S. M. & Curtis, D. J., 14 Aug 2018, In : Blood Advances. 2, 15, p. 1914-1922 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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