• Australian Centre for Blood Diseases Central Clinical School, Monash University Level 1, Walkway via The Alfred Centre, 99 Commercial Road, Melbourne 3004


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Personal profile


Dr. Brown completed her PhD in 2013 at the University of Melbourne. During her PhD, Dr. Brown studied the molecular mechanisms underpinning anaemia, including iron deficiency anaemia and beta thalassaemia, the most common causes of anaemia. She then worked as a Research Fellow at Memorial Sloan Kettering Cancer Center in New York, USA, where she studied pathways regulating chemotherapy resistance in acute meloid leukaemia (AML). In 2017, she moved to the Australian Ceneter for Blood Diseases, Monash University based at the Alfred Hospital. Here she is investigating improved targeted therapeutic strategies in AML. 

Research area keywords

  • Acute myeloid leukaemia
  • resistance dynamics

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Projects 2020 2024

  • 1 Not started

Research Output 2013 2019

KCC1 Activation protects Mice from the Development of Experimental Cerebral Malaria

Hortle, E., Starrs, L., Brown, F., Jane, S., Curtis, D., McMorran, B. J., Foote, S. J. & Burgio, G., 1 Dec 2019, In : Scientific Reports. 9, 1, 11 p., 6356.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2 Citations (Scopus)

Bone marrow transplantation corrects haemolytic anaemia in a novel ENU mutagenesis mouse model of TPI deficiency

Conway, A., Brown, F. C., Hortle, E. J., Burgio, G., Foote, S. J., Morton, C. J., Jane, S. M. & Curtis, D. J., 21 May 2018, In : Disease Models and Mechanisms. 11, 5, 8 p., dmm034678.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Characterization of Tfrc-mutant mice with microcytic phenotypes

Conway, A. J., Brown, F. C., Rank, G., Kile, B. T., Morton, C. J., Jane, S. M. & Curtis, D. J., 14 Aug 2018, In : Blood Advances. 2, 15, p. 1914-1922 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
15 Citations (Scopus)

DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia

Johnson, D. C., Taabazuing, C. Y., Okondo, M. C., Chui, A. J., Rao, S. D., Brown, F. C., Reed, C., Peguero, E., de Stanchina, E., Kentsis, A. & Bachovchin, D. A., 1 Aug 2018, In : Nature Medicine. 24, 8, p. 1151-1156 6 p.

Research output: Contribution to journalLetterResearchpeer-review

9 Citations (Scopus)

MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia

Brown, F. C., Still, E., Koche, R. P., Yim, C. Y., Takao, S., Cifani, P., Reed, C., Gunasekera, S., Ficarro, S. B., Romanienko, P., Mark, W., McCarthy, C., de Stanchina, E., Gonen, M., Seshan, V., Bhola, P., O’Donnell, C., Spitzer, B., Stutzke, C., Lavallée, V. P. & 12 others, Hébert, J., Krivtsov, A. V., Melnick, A., Paietta, E. M., Tallman, M. S., Letai, A., Sauvageau, G., Pouliot, G., Levine, R., Marto, J. A., Armstrong, S. A. & Kentsis, A., 1 Apr 2018, In : Cancer Discovery. 8, 4, p. 478-497 20 p.

Research output: Contribution to journalArticleResearchpeer-review