20122023

Research activity per year

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Personal profile

Biography

Dr. Evan Healy completed his PhD in 2019 in Prof. Adrian Bracken's lab at Trinity College Dublin, Ireland. His doctoral work focused on defining how specific components of the Polycomb Repressive Complex (PRC) machinery synergise to coordinate genome wide activites. Dr. Healy was recruited to the Biomedicine Discovery Institute at Monash University in November 2021, where he is currently a postdoctoral research fellow in the Davidovich Lab. His current research focus is to understand the molecular mechanisms underlying chromatin and transcriptional regulation with a particular focus on the role RNA plays in this process. 

Research interests

In all multicellular organisms, cellular identity is defined by distinct gene expression programmes that are stably maintained throughout life. Coordination of gene expression is linked to the three-dimensional packaging of genomic DNA into chromatin. 

My research interests are focused on the molecular mechanisms underlying chromatin and transcriptional regulation. Mutations in chromatin regulators that control these processes often drive human disease such as cancer and neurodevelopmental syndromes. In particular, I study how chromatin and chromatin regulators are modulated by RNA. The ultimate goal of my research is to leverage basic biological discoveries in this area to uncover novel therapuetic strategies. 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Genetics, PhD, Understanding the Diverse Roles of Polycomb-like proteins in the Regulation of Chromatin and Transcriptional Landscapes, Trinity College Dublin

1 Sept 201530 Jan 2019

Award Date: 20 Jun 2019

Research area keywords

  • Chromatin biology
  • Epigenetics
  • Transcriptional Regulation

Collaborations and top research areas from the last five years

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