Projects per year
Personal profile
Biography
Professor Eric Morand is Head of the School of Clinical Sciences at Monash Health, Monash University's largest clinical school, and a physician-scientist.
He specialises in the study of systemic lupus erythematosus. He is founder of the Monash Lupus Clinic, Australia's largest research-grounded clinic for patients with SLE, a founding member of the Australian Lupus Registry & Biobank, and Chair of the Asia-Pacific Lupus Collaboration. His clinical research focuses on improving endpoints for clinical research in lupus. His lab has studied the biology of glucocorticoids in rheumatic disease and lupus since 1996.
He is a clinical rheumatologist, and Head of the Monash Health Rheumatology Unit, the largest in Australia.
Research interests
Professor Morand is a physician-scientist whose key interests are clinical outcome measurement and biological profiling in SLE, and the actions of glucocorticoid induced proteins on the immune system. Read more at https://www.monash.edu/medicine/scs/researchers/eric-morand .
His group has pioneered the development and validation of treat-to-target outcome measures in SLE, via the Asia-Pacific Lupus Collaboration, which with over 2,800 patients under study is the largest cohort of SLE patients ever assembled.
Biomarker studies in SLE are also a major focus, with thousands of samples linked to longitudinal clinical data archived in the Australian Lupus Registry & Biobank, headquartered at Monash.
His lab discovered the role in rheumatic disease of multiple important glucocorticoid-regulated proteins. Most recently his group defined the role of GILZ in RA, Th17 pathways, B cell activation, and lupus, and are working on exploiting its actions to develop a safe glucocorticoid mimic. His lab also works on innate immunity including the actions of the unique pro-inflammatory protein, MIF.
Clinical activities
Professor Morand is Head of Rheumatology, Monash Health. He works in clinics servicing lupus, rheumatoid arthritis, and complex rheumatology cases, and undertakes ward duty inpatient care in the largest service in the country.
Consulting
Advisory expertise and research collaboration experience with international biotech and Pharma companies.
Special interests include Lupus / SLE outcome measures, trials, translational research and biomarkers.
Community service
Professor Morand is a Board member of Rare Voices Australia, has served on the board of the Australian Rheumatology Association and is a member of the Scientific Advisory Board of the ARA Research Trust.
Research area keywords
- Systemic Lupus Erythematosus
- glucocorticoids
- Lupus
- SLE
- RA
- GILZ
- MIF
- Rheumatoid Arthritis
- Rheumatology
- outcome measures
- Clinical Trials
- Translational Research
- Cytokines
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects
Unmet need for targeted therapies in Australian and AsiaPacific SLE patients
Morand, E. & Kandane-Rathnayake, R.
20/11/19 → 30/11/20
Project: Research
Treat-to-Target in Systemic Lupus Erythematosus (SLE)
Morand, E. & Kandane-Rathnayake, R.
3/10/19 → 3/10/21
Project: Research
Treat-to-Target in Systemic Lupus Erythematosus (LLDAS Study - Extension Phase)
Morand, E. & Kandane-Rathnayake, R.
14/05/19 → 11/12/22
Project: Research
Treat-to-Target in Systemic Lupus Erythematosus (LLDAS Study - Extension Phase)
Morand, E. & Kandane-Rathnayake, R.
5/02/19 → 30/09/22
Project: Research
Treat-to-Target in Systemic Lupus Erythematosus (LLDAS Study - Extension Phase)
Morand, E. & Kandane-Rathnayake, R.
15/01/19 → 31/12/22
Project: Research
Research Output
Assays for Inducing and Measuring Cell Death to Detect Macrophage Migration Inhibitory Factor (MIF) Release
Zamani, S., Morand, E. F. & Flynn, J. K., 1 Jan 2020, In : Methods in molecular biology (Clifton, N.J.). 2080, p. 173-183 11 p.Research output: Contribution to journal › Article › Other › peer-review
Comparison of performance of specific (SLEQOL) and generic (SF36) health-related quality of life questionnaires and their associations with disease status of systemic lupus erythematosus: a longitudinal study
Louthrenoo, W., Kasitanon, N., Morand, E. & Kandane-Rathnayake, R., 10 Jan 2020, In : Arthritis Research & Therapy. 22, 1, 12 p., 8.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Connexin-Dependent Transfer of cGAMP to Phagocytes Modulates Antiviral Responses
Pépin, G., De Nardo, D., Rootes, C. L., Ullah, T. R., Al-Asmari, S. S., Balka, K. R., Li, H-M., Quinn, K. M., Moghaddas, F., Chappaz, S., Kile, B. T., Morand, E. F., Masters, S. L., Stewart, C. R., Williams, B. R. G. & Gantier, M. P., 28 Jan 2020, In : mBio. 11, 1, 6 p., e03187-19.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Factors associated with damage accrual in patients with systemic lupus erythematosus with no clinical or serological disease activity: a multicentre cohort study
Apostolopoulos, D., Kandane-Rathnayake, R., Louthrenoo, W., Luo, S. F., Jan Wu, Y. J., Lateef, A., Golder, V., Sockalingam, S., Navarra, S. T. V., Zamora, L., Hamijoyo, L., Katsumata, Y., Harigai, M., Chan, M., O'Neill, S., Goldblatt, F., Lau, C. S., Li, Z. G., Hoi, A., Nikpour, M. & 2 others, , Jan 2020, In : The Lancet Rheumatology. 2, 1, p. e24-e30 7 p.Research output: Contribution to journal › Article › Research › peer-review
1
Citation
(Scopus)
Plasmacytoid dendritic cells from parent strains of the NZB/W F1 lupus mouse contribute different characteristics to autoimmune propensity
Zhan, Y., Kong, I., Chopin, M., Macri, C., Zhang, J. G., Xie, J., Nutt, S. L., O'Keeffe, M., Hawkins, E. D., Morand, E. F. & Lew, A. M., 9 Jan 2020, (Accepted/In press) In : Immunology and Cell Biology. 12 p.Research output: Contribution to journal › Article › Research › peer-review
Prizes
Dean's Award for Research (Enterprise)
Eric Morand (Recipient), 1 Aug 2018
Prize: Prize (including medals and awards)
Distinguished Innovator Award, Lupus Research Alliance
Eric Morand (Recipient), 2015
Prize: National/international honour
Paper selected for the Best of Immunology & Cell Biology (ICB)/ Clinical and Translational Immunology (CTI) Workshop at the 2019 Australian & New Zealand Society for Immunology (ASI) Annual Scientific Meeting
Fabien Vincent (Recipient), James Harris (Recipient), Eric Morand (Recipient), Joanne Sahhar (Recipient), Gene Ngian (Recipient), Rangi Kandane-Rathnayake (Recipient), Tali Lang (Recipient), Emily Lin (Recipient) & Rachel Mende (Recipient), 11 Dec 2019
Prize: Prize (including medals and awards)
Parr Prize for Research, Australian Rheumatology Association
Eric Morand (Recipient), 2001
Prize: Prize (including medals and awards)