Projects per year
Personal profile
Biography
Dr Emma Watson completed her PhD under the supervision of Professor Richard Payne at the University of Sydney, where her research focused on developing synthetic methods to access post-translationally modified proteins. She then completed a postdoctoral appointment in the group of Professor Nicolas Winssinger at the University of Geneva as an EMBO postdoctoral fellow, working on logic gated biosupramolecular systems for oncology. She then returned to Australia in 2022 to begin her independent career at the University of Adelaide before moving to MIPS in 2025 as a Senior Lecturer and ARC DECRA Fellow. Her research focuses on developing responsive therapeutic systems based on biomolecules, which are capable of leveraging Boolean logic to improve safety and precision.
Research interests
- Developing new methodologies for protein synthesis and late stage modification
- Exploring post-translational modifications as a means of regulating the function of therapeutically relevant proteins
- Using nucleic acid mimics (PNA - Peptide Nucleic Acids) as components in molecular circuits to enable targetted drug delivery or activation
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Chemical Synthesis
- Chemical Biology
- Peptide Chemistry
- Nucleic Acid Sensors
- Protein Chemistry
Collaborations and top research areas from the last five years
Projects
- 1 Active
-
Site-specific protein functionalisation at diselenides via photocatalysis
Payne, R. (Chief Investigator (CI)) & Watson, E. (Primary Chief Investigator (PCI))
17/02/25 → 22/01/26
Project: Research
-
Peptide Nucleic Acids: From Origami to Editing
Carson, L. M. & Watson, E. E., Nov 2024, In: ChemPlusChem. 89, 11, 11 p., e202400305.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access7 Citations (Scopus) -
Exploiting Chemical Protein Synthesis to Study the Role of Tyrosine Sulfation on Anticoagulants from Hematophagous Organisms
Maxwell, J. W. C., Hawkins, P. M. E., Watson, E. E. & Payne, R. J., 14 Sept 2023, In: Accounts of Chemical Research. 56, 19, p. 2688-2699 12 p.Research output: Contribution to journal › Article › Research › peer-review
10 Citations (Scopus) -
Rapid Synthesis of Propargyl-γ-Modified Peptide Nucleic Acid Monomers for Late-Stage Functionalization of Oligomers
López-Tena, M., Watson, E. E., Romanens, P. & Winssinger, N., Nov 2023, In: Helvetica Chimica Acta. 106, 11, 14 p., e202300110.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
Biosupramolecular networks: Taking inspiration from nature to create powerful synthetic platforms
Watson, E. E. & Winssinger, N., Feb 2022, In: Current Opinion in Chemical Biology. 66, 8 p., 102104.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access4 Citations (Scopus) -
Expressed Protein Selenoester Ligation
Kulkarni, S. S., Watson, E. E., Maxwell, J. W. C., Niederacher, G., Johansen-Leete, J., Huhmann, S., Mukherjee, S., Norman, A. R., Kriegesmann, J., Becker, C. F. W. & Payne, R. J., 9 May 2022, In: Angewandte Chemie - International Edition. 61, 20, 6 p., e202200163.Research output: Contribution to journal › Article › Research › peer-review
Open Access30 Citations (Scopus)