Emma van der Westhuizen

Research Fellow, Drug Discovery Biology

https://orcid.org/0000-0001-9165-8526

EmailEmma.VanDerWesthuizen@monash.edu

Research activity per year

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Personal profile

Biography

Position
Research Fellow
Faculty of Pharmacy and Pharmaceutical Sciences

Drug Discovery Biology
Monash Institute of Pharmaceutical Sciences

Dr Van Der Westhuizen obtained her PhD in Molecular Pharmacology from Monash University in 2008, and was then awarded post-doctoral fellowships from the Canadian Institutes for Health Research, Canadian Hypertension Society, Heart and Stroke Foundation of Canada, Fonds de Recherche Sante Quebec and an NHMRC Early Career Fellowship to support her post-doctoral studies at the University of Montreal, Canada. In 2014, she returned to Australia to the Monash Institute of Pharmaceutical Sciences to continue post-doctoral studies within the Drug Discovery Biology Group.

External positions

Post-doctoral research fellow, Université de Montréal (University of Montreal)

Nov 2008 → Nov 2013

Research Assistant, Prince Henry's Institute of Medical Research

Mar 2000 → Apr 2001

Network

Recent external collaboration on country level. Dive into details by clicking on the dots or

1 Finished

Exploring the molecular basis of ligand-directed activity in G protein-coupled receptor signalling diversity using the beta adrenergic and muscarinic acetylcholine receptors as models.
van der Westhuizen, E.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/11 → 30/06/19
Project: Research

25 Article
2 Conference Paper
2 Comment / Debate
1 Chapter (Book)

Development of Novel 4-Arylpyridin-2-one and 6-Arylpyrimidin-4-one Positive Allosteric Modulators of the M₁ Muscarinic Acetylcholine Receptor
Jörg, M., Khajehali, E., van der Westhuizen, E. T., C. Choy, K. H., Shackleford, D. M., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 8 Jan 2021, In: ChemMedChem. 16, 1, p. 216-233 18 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

1 Citation (Scopus)
Author Correction: Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response (Nature Communications, (2019), 10, 1, (4075), 10.1038/s41467-019-11875-6)
Benredjem, B., Gallion, J., Pelletier, D., Dallaire, P., Charbonneau, J., Cawkill, D., Nagi, K., Gosink, M., Lukasheva, V., Jenkinson, S., Ren, Y., Somps, C., Murat, B., Van Der Westhuizen, E., Le Gouill, C., Lichtarge, O., Schmidt, A., Bouvier, M. & Pineyro, G., 1 Dec 2020, In: Nature Communications. 11, 1, 1 p., 1929.
Research output: Contribution to journal › Comment / Debate › Other › peer-review

Open Access
Restoring Agonist Function at a Chemogenetically Modified M₁Muscarinic Acetylcholine Receptor
Khajehali, E., Bradley, S., Van Der Westhuizen, E. T., Molloy, C., Valant, C., Finlayson, L., Lindsley, C. W., Sexton, P. M., Tobin, A. B. & Christopoulos, A., 16 Dec 2020, In: ACS Chemical Neuroscience. 11, 24, p. 4270–4279 10 p.
Research output: Contribution to journal › Article › Research › peer-review
6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M₁ mAChR: The Determinants of Allosteric Activity
Jorg, M. T., van der Westhuizen, E. T., Khajehali, E., Burger, W. A. C., White, J., Choy, K. H. C., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 20 Mar 2019, In: ACS Chemical Neuroscience. 10, 3, p. 1099-1114 16 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

3 Citations (Scopus)
Crystal structure of the M₅ muscarinic acetylcholine receptor
Vuckovic, Z., Gentry, P. R., Berizzi, A. E., Hirata, K., Varghese, S., Thompson, G., van der Westhuizen, E. T., Burger, W. A. C., Rahmani, R., Valant, C., Langmead, C. J., Lindsley, C. W., Baell, J. B., Tobin, A. B., Sexton, P. M., Christopoulos, A. & Thal, D. M., 17 Dec 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 51, p. 26001-26007 7 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

4 Citations (Scopus)

Canadian Institutes of Health Research in partnership with Canadian Hypertension Society Fellowship
van der Westhuizen, Emma (Recipient), 24 Apr 2008
Prize: Competitive Fellowships
Fonds de la recherche en sante Quebec bourse
van der Westhuizen, Emma (Recipient), 11 Apr 2008
Prize: Competitive Fellowships
Fonds de la recherche en sante Quebec bourse renouvellement
van der Westhuizen, Emma (Recipient), 28 Apr 2011
Prize: Competitive Fellowships
Heart and Stroke Foundation of Canada Research Fellowship
van der Westhuizen, Emma (Recipient), 4 Apr 2008
Prize: Competitive Fellowships
National Health and Medical Research Council Australia Dora Lush PhD scholarship
van der Westhuizen, Emma (Recipient), 2004
Prize: Other distinction

1 Peer review responsibility

British Journal of Pharmacology (Journal)
Emma Van Der Westhuizen (Peer reviewer)
17 Feb 2012 → 10 May 2021
Activity: Publication peer-review and editorial work types › Peer review responsibility