Elva Zhao

Dr

Accepting PhD Students

20092021

Research activity per year

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Personal profile

Biography

To Elva science is about imagination and curiosity. Research gives her the opportunity to use her knowledge to decipher the unknown. Her research interest is in regulation of cellular signaling, and how these complex events can translate into human physiology and pathophysiology. Her receptors of interest are called protease-activated receptors (PARs). PARs plays critical role in regulating inflammation and pain signaling. To understand how PARs function at cellular, tissue and whole animal level will provide novel mechanisms in pain transmission and further facilitate the development of new pain therapies.

Selected recent publications

 

1.Zhao P, Canals M, Murphy JE, Klingler D, Eriksson EM, Pelayo J-C, et al. Agonist-biased Trafficking of Somatostatin Receptor 2A in Enteric Neurons. J. Biol. Chem. 2013 Sep 6;288(36):25689-700.

2.Zhao P, Cladman W, Van Tol HHM, Chidiac P. Fine-tuning of GPCR signals by intracellular G protein modulators. Prog Mol Biol Transl Sci. 2013;115:421-53.

3.Zhao P, Nguyen CH, Chidiac P. The proline-rich N-terminal domain of G18 exhibits a novel G protein regulatory function. J. Biol. Chem. 2010 Mar 19;285(12):9008-17.

4.Nunn C, Zhao P, Zou M-X, Summers K, Guglielmo CG, Chidiac P. Resistance to age-related, normal body weight gain in RGS2 deficient mice. Cell. Signal. 2011 Aug;23(8):1375-86.

5.Nguyen CH, Ming H, Zhao P, Hugendubler L, Gros R, Kimball SR, et al. Translational control by RGS2. J. Cell Biol. 2009 Sep 7;186(5):755-65.

6.Zhao P, Nunn C, Ramineni S, Hepler JR, Chidiac P. The Ras-binding domain region of RGS14 regulates its functional interactions with heterotrimeric G proteins. J Cell Biochem. 2013 Jun 15;114(6):1414-23.

Network

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