Elizabeth Algar

Adj Assoc Prof

20092019

Research output per year

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Research Output

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Article
2019

ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer

Saad, M. I., Alhayyani, S., McLeod, L., Yu, L., Alanazi, M., Deswaerte, V., Tang, K., Jarde, T., Smith, J. A., Prodanovic, Z., Tate, M. D., Balic, J. J., Watkins, D. N., Cain, J. E., Bozinovski, S., Algar, E., Kohmoto, T., Ebi, H., Ferlin, W., Garbers, C. & 4 others, Ruwanpura, S., Sagi, I., Rose-John, S. & Jenkins, B. J., Apr 2019, In : EMBO Molecular Medicine. 11, 4, 19 p., e9976.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)
2018

Genetic variation affecting DNA methylation and the human imprinting disorder, Beckwith-Wiedemann syndrome

Dagar, V., Hutchison, W., Muscat, A., Krishnan, A., Hoke, D., Buckle, A., Siswara, P., Amor, D. J., Mann, J., Pinner, J., Colley, A., Wilson, M., Sachdev, R., McGillivray, G., Edwards, M., Kirk, E., Collins, F., Jones, K., Taylor, J., Hayes, I. & 14 others, Thompson, E., Barnett, C., Haan, E., Freckmann, M-L., Turner, A., White, S., Kamien, B., Ma, A., Mackenzie, F., Baynam, G., Kiraly-Borri, C., Field, M., Dudding-Byth, T. & Algar, E., 30 Aug 2018, In : Clinical Epigenetics. 10, 1, 13 p., 114.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection

Muscat, A. M., Wong, N. C., Drummond, K. J., Algar, E. M., Khasraw, M., Verhaak, R., Field, K., Rosenthal, M. A. & Ashley, D. M., 1 Jan 2018, In : Oncotarget. 9, 8, p. 7844-7858 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)
2017

Atypical teratoid rhabdoid tumor: Two case reports and an analysis of adult cases with implications for pathophysiology and treatment

Dardis, C., Yeo, J., Milton, K., Ashby, L. S., Smith, K. A., Mehta, S., Youssef, E., Eschbacher, J., Tucker, K., Dawes, L., Lambie, N., Algar, E. & Hovey, E., 20 Jun 2017, In : Frontiers in Neurology. 8, JUN, 247.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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6 Citations (Scopus)

Endoscopic ultrasound-guided fine-needle aspirate-derived preclinical pancreatic cancer models reveal panitumumab sensitivity in KRAS wild-type tumors

Berry, W., Algar, E., Kumar, B., Desmond, C., Swan, M., Jenkins, B. J. & Croagh, D., 15 May 2017, In : International Journal of Cancer. 140, 10, p. 2331-2343 13 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)
2016

Low-dose histone deacetylase inhibitor treatment leads to tumor growth arrest and multi-lineage differentiation of malignant rhabdoid tumors

Muscat, A., Popovski, D., Jayasekara, W. S. N., Rossello, F. J., Ferguson, M., Marini, K. D., Alamgeer, M., Algar, E. M., Downie, P., Watkins, D. N., Cain, J. E. & Ashley, D., 15 Jul 2016, In : Clinical Cancer Research. 22, 14, p. 3560-3570 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
17 Citations (Scopus)
2014

Cancer risks for relatives of children with cancer

Heath, J. A., Smibert, E., Algar, E. M., Dite, G. S. & Hopper, J. L., 2014, In : Journal of Cancer Epidemiology. 2014, 4 p., 806076.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

Clinical utility gene card for: Beckwith-Wiedemann Syndrome

Eggermann, T., Algar, E., Lapunzina, P., MacKay, D., Maher, E. R., Mannens, M., Netchine, I., Prawitt, D., Riccio, A., Temple, I. K. & Weksberg, R., Mar 2014, In : European Journal of Human Genetics. 22, 3, p. 435 1 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
28 Citations (Scopus)
2013

Bilateral Wilms tumor and early presentation in pediatric patients is associated with the truncation of the Wilms tumor 1 protein

Hu, M., Fletcher, J., McCahon, E., Catchpoole, D., Zhang, G. Y., Wang, Y. M., Algar, E. M. & Alexander, S. I., 2013, In : Journal of Pediatrics. 163, 1, p. 224-229 6 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes

Birks, D. K., Donson, A. M., Patel, P. R., Sufit, A., Algar, E. M., Dunham, C., Kleinschmidt-DeMasters, B. K., Handler, M. H., Vibhakar, R. & Foreman, N. O. K., Jul 2013, In : Pediatric Blood and Cancer. 60, 7, p. 1095-1102 8 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

The oncogenic properties of EWS/WT1 of desmoplastic small round cell tumors are unmasked by loss of p53 in murine embryonic fibroblasts

Bandopadhayay, P., Jabbour, A. M., Riffkin, C. D., Salmanidis, M., Gordon, L., Popovski, D., Rigby, L., Ashely, D. M., Watkins, D. N., Thomas, D. M., Algar, E. M. & Ekert, P. G., 2013, In : BMC Cancer. 13, Art # 585, p. 1 - 14 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
5 Citations (Scopus)
2012

A distinct DNA methylation signature defines pediatric pre-B cell acute lymphoblastic leukemia

Wong, N. C., Ashley, D., Chatterton, Z., Parkinson-Bates, M., Ng, H. K., Halemba, M. S., Kowalczyk, A., Bedo, J., Wang, Q. J., Bell, K. M., Algar, E., Craig, J. M. & Saffery, R., 1 Jan 2012, In : Epigenetics. 7, 6, p. 535-541 7 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Methods for the analysis of histone H3 and H4 acetylation in blood

Rigby, L., Muscat, A., Ashley, D. & Algar, E., 2012, In : Epigenetics. 7, 8, p. 875-882 8 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Possible role of WT1 in a human fetus with evolving bronchial atresia, pulmonary malformation and renal agenesis

Loo, C. K. C., Algar, E. M., Payton, D. J., Perry-Keene, J., Pereira, T. N. & Ramm, G. A., 2012, In : Pediatric and Developmental Pathology. 15, 1, p. 39-44 6 p.

Research output: Contribution to journalArticleOtherpeer-review

3 Citations (Scopus)
2011

An 11p15 imprinting centre region 2 deletion in a family with beckwith wiedemann syndrome provides insights into imprinting control at CDKN1C

Algar, E., Dagar, V., Sebaj, M. & Pachter, N., 19 Dec 2011, In : PLoS ONE. 6, 12, e29034.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
22 Citations (Scopus)

High expression of BMP pathway genes distinguishes a subset of atypical teratoid/rhabdoid tumors associated with shorter survival

Birks, D. K., Donson, A. M., Patel, P. R., Dunham, C., Muscat, A., Algar, E. M., Ashley, D. M., Kleinschmidt-DeMasters, B. K., Vibhakar, R., Handler, M. H. & Foreman, N. O. K., Dec 2011, In : Neuro-Oncology. 13, 12, p. 1296-1307 12 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)
2010

A Phase II trial of primary temozolomide in patients with grade III oligodendroglial brain tumors

Gan, H. K., Rosenthal, M. A., Dowling, A. J., Kalnins, R., Algar, E., Wong, N., Benson, A., Woods, A. M. & Cher, L., May 2010, In : Neuro-Oncology. 12, 5, p. 500-507 8 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Russell-Silver syndrome due to paternal H19/IGF2 hypomethylation in a patient conceived using intracytoplasmic sperm injection

Chopra, M., Amor, D. J., Sutton, L., Algar, E. & Mowat, D., Jun 2010, In : Reproductive BioMedicine Online. 20, 6, p. 843-847 5 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)
2009

Imprinted CDKN1C is a tumor suppressor in rhabdoid tumor and activated by restoration of SMARCB1 and histone deacetylase inhibitors

Algar, E. M., Muscat, A., Dagar, V., Rickert, C., Chow, C. W., Biegel, J. A., Ekert, P. G., Saffery, R., Craig, J. M., Johnstone, R. W. & Ashley, D. M., 16 Feb 2009, In : PLoS ONE. 4, 2, e4482.

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)

Rapid detection of SMARCB1 sequence variation using high resolution melting

Dagar, V., Chow, C. W., Ashley, D. M. & Algar, E. M., 13 Dec 2009, In : BMC Cancer. 9, 437.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)