Ee Ming Wong

Dr

Accepting PhD Students

20052019
If you made any changes in Pure these will be visible here soon.

Research Output 2005 2019

2019

Assessing the ProMCol classifier as a prognostic marker for non-metastatic colorectal cancer within the Melbourne Collaborative Cohort Study

Joo, J. E., Jayasekara, H., Wong, E. M., Clendenning, M., Rosty, C., Winship, I. M., Jenkins, M. A., Hopper, J. L., English, D. R., Milne, R. L., Giles, G. G., Southey, M. C. & Buchanan, D. D., 1 Apr 2019, In : Gut. 68, 4, p. 761-762 2 p.

Research output: Contribution to journalLetterOtherpeer-review

Dietary Intake of Nutrients Involved in One-Carbon Metabolism and Risk of Gastric Cancer: A Prospective Study

Dugué, P. A., Bassett, J. K., Brinkman, M. T., Southey, M. C., Joo, J. E., Wong, E. M., Milne, R. L., English, D. R., Giles, G. G., Boussioutas, A., Mitchell, H. & Hodge, A. M., 19 May 2019, In : Nutrition and Cancer-An International Journal. 71, 4, p. 605-614 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Genome-wide association study of peripheral blood DNA methylation and conventional mammographic density measures

Li, S., Dugué, P. A., Baglietto, L., Severi, G., Wong, E. M., Nguyen, T. L., Stone, J., English, D. R., Southey, M. C., Giles, G. G., Hopper, J. L. & Milne, R. L., 1 Jan 2019, In : International Journal of Cancer. 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Inference about causation between body mass index and DNA methylation in blood from a twin family study

Li, S., Wong, E. M., Bui, M., Nguyen, T. L., Joo, J. H. E., Stone, J., Dite, G. S., Dugué, P. A., Milne, R. L., Giles, G. G., Saffery, R., Southey, M. C. & Hopper, J. L., 1 Feb 2019, In : International Journal of Obesity. 43, 2, p. 243-252 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Physical Activity, Television Viewing Time, and DNA Methylation in Peripheral Blood

Van Roekel, E. H., Dugué, P. A., Jung, C. H., Joo, J. E., Makalic, E., Wong, E. M., English, D. R., Southey, M. C., Giles, G. G., Lynch, B. M. & Milne, R. L., 1 Mar 2019, In : Medicine and Science in Sports and Exercise. 51, 3, p. 490-498 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2018
14 Citations (Scopus)

Association of dna methylation-based biological age with health risk factors and overall and cause-specific mortality

Dugué, P. A., Bassett, J. K., Joo, J. E., Baglietto, L., Jung, C. H., Wong, E. M., Fiorito, G., Schmidt, D., Makalic, E., Li, S., Moreno-Betancur, M., Buchanan, D. D., Vineis, P., English, D. R., Hopper, J. L., Severi, G., Southey, M. C., Giles, G. G. & Milne, R. L., 1 Mar 2018, In : American Journal of Epidemiology. 187, 3, p. 529-538 10 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Causal effect of smoking on DNA methylation in peripheral blood: A twin and family study

Li, S., Wong, E. M., Bui, M., Nguyen, T. L., Joo, J. H. E., Stone, J., Dite, G. S., Giles, G. G., Saffery, R., Southey, M. C. & Hopper, J. L., 9 Feb 2018, In : Clinical Epigenetics. 10, 1, 12 p., 18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
20 Citations (Scopus)

DNA methylation-based biological aging and cancer risk and survival: pooled analysis of seven prospective studies

Dugué, P. A., Bassett, J. K., Joo, J. E., Jung, C. H., Ming Wong, E., Moreno-Betancur, M., Schmidt, D., Makalic, E., Li, S., Severi, G., Hodge, A. M., Buchanan, D. D., English, D. R., Hopper, J. L., Southey, M. C., Giles, G. G. & Milne, R. L., 15 Apr 2018, In : International Journal of Cancer. 142, 8, p. 1611-1619 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
4 Citations (Scopus)

Genome-wide average DNA methylation is determined in utero

Li, S., Wong, E. M., Dugué, P. A., McRae, A., Kim, E., Joo, J. E., Nguyen, T. L., Stone, J. L., Dite, G. S., Armstrong, N., Mather, K. A., Thalamuthu, A., Wright, M. J., Ames, D. J., Milne, R. L., Craig, J. M., Saffery, R., Montgomery, G. W., Song, Y. M., Sung, J. & 5 others, Spector, T. D., Sachdev, P. S., Giles, G. G., Southey, M. C. & Hopper, J. L., 1 Jun 2018, In : International Journal of Epidemiology. 47, 3, p. 908-916 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Genome-wide DNA methylation assessment of ‘BRCA1-like’ early-onset breast cancer: Data from the Australian Breast Cancer Family Registry

Scott, C. M., Wong, E. M., Joo, J. H. E., Dugué, P. A., Jung, C. H., O'Callaghan, N., Dowty, J., Giles, G. G., Hopper, J. L. & Southey, M. C., 1 Dec 2018, In : Experimental and Molecular Pathology. 105, 3, p. 404-410 7 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Heritable DNA methylation marks associated with susceptibility to breast cancer

Joo, J. E., Dowty, J. G., Milne, R. L., Wong, E. M., Dugué, P. A., KConFab, English, D., Hopper, J. L., Goldgar, D. E., Giles, G. G. & Southey, M. C., 28 Feb 2018, In : Nature Communications. 9, 1, 12 p., 867.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Heritable methylation marks associated with breast and prostate cancer risk

Dugué, P. A., Dowty, J. G., Joo, J. E., Wong, E. M., Makalic, E., Schmidt, D. F., English, D. R., Hopper, J. L., Pedersen, J., Severi, G., MacInnis, R. J., Milne, R. L., Giles, G. G. & Southey, M. C., 15 Sep 2018, In : Prostate. 78, 13, p. 962-969 8 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Novel associations between blood DNA methylation and body mass index in middle-Aged and older adults

Geurts, Y. M., Dugué, P. A., Joo, J. E., Makalic, E., Jung, C. H., Guan, W., Nguyen, S., Grove, M. L., Wong, E. M., Hodge, A. M., Bassett, J. K., FitzGerald, L. M., Tsimiklis, H., Baglietto, L., Severi, G., Schmidt, D. F., Buchanan, D. D., MacInnis, R. J., Hopper, J. L., Pankow, J. S. & 5 others, Demerath, E. W., Southey, M. C., Giles, G. G., English, D. R. & Milne, R. L., 1 Apr 2018, In : International Journal of Obesity. 42, 4, p. 887-896 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Obtaining high quality transcriptome data from formalin-fixed, paraffin-embedded diagnostic prostate tumor specimens

Fitzgerald, L. M., Jung, C. H., Wong, E. M., Joo, J. H. E., Gould, J. A., Vasic, V., Bassett, J. K., O'Callaghan, N., Nottle, T., Pedersen, J., Giles, G. G. & Southey, M. C., 1 Apr 2018, In : Laboratory Investigation. 98, 4, p. 537-550 14 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

The utility of DNA extracted from saliva for genome-wide molecular research platforms

Bruinsma, F. J., Joo, J. E., Wong, E. M., Giles, G. G. & Southey, M. C., 8 Jan 2018, In : BMC Research Notes. 11, 1, 6 p., 8.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2017
3 Citations (Scopus)

Association between DNA methylation at SOCS3 gene and body mass index might be due to familial confounding

Li, S., Wong, E. M., Southey, M. C. & Hopper, J. L., 1 Jun 2017, In : International Journal of Obesity. 41, 6, p. 995-996 2 p.

Research output: Contribution to journalLetterOtherpeer-review

2 Citations (Scopus)

Causes of blood methylomic variation for middle-aged women measured by the HumanMethylation450 array

Li, S., Wong, E. M., Nguyen, T. L., Joo, J. H. E., Stone, J., Dite, G. S., Giles, G. G., Saffery, R., Southey, M. C. & Hopper, J. L., 2 Nov 2017, In : Epigenetics. 12, 11, p. 973-981 9 p.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk

Baglietto, L., Ponzi, E., Haycock, P., Hodge, A., Bianca Assumma, M., Jung, C-H., Chung, J., Fasanelli, F., Guida, F., Campanella, G., Chadeau-Hyam, M., Grankvist, K., Johansson, M., Ala, U., Provero, P., Wong, E. M., Joo, J. E., English, D. R., Kazmi, N., Lund, E. E. & 12 others, Faltus, C., Kaaks, R. J., Risch, A., Barrdahl, M., Sandanger, T. M., Southey, M. C., Giles, G. G., Johansson, M., Vineis, P., Polidoro, S., Relton, C. L. & Severi, G., 1 Jan 2017, In : International Journal of Cancer. 140, 1, p. 50-61 12 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Genome-Wide Measures of Peripheral Blood Dna Methylation and Prostate Cancer Risk in a Prospective Nested Case-Control Study

Fitzgerald, L. M., Naeem, H., Makalic, E., Schmidt, D. F., Dowty, J. G., Joo, J. E., Jung, C-H., Bassett, J. K., Dugue, P. A., Chung, J., Lonie, A., Milne, R. L., Wong, E. M., Hopper, J. L., English, D. R., Severi, G., Baglietto, L., Pedersen, J., Giles, G. G. & Southey, M. C., 1 Apr 2017, In : Prostate. 77, 5, p. 471-478 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Heritable methylation marks associated with breast cancer risk: what role do they play in tumourigenesis?

Wong, E. M., 2017.

Research output: Contribution to conferencePosterOtherpeer-review

1 Citation (Scopus)

Twin birth changes DNA methylation of subsequent siblings

Li, S., Kim, E., Wong, E. M., Joo, J. H. E., Nguyen, T. L., Stone, J., Song, Y. M., Flander, L. B., Saffery, R., Giles, G. G., Southey, M. C., Sung, J. & Hopper, J. L., 1 Dec 2017, In : Scientific Reports. 7, 1, 8 p., 8463.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2016
2 Citations (Scopus)

Analysis of the breast cancer methylome using formalin-fixed paraffin-embedded tumour

Wong, E. M., Joo, J. H. E., McLean, C. A., Baglietto, L., English, D. R., Severi, G., Wu, H. C., Terry, M. B., Hopper, J. L., Milne, R. L., Giles, G. G. & Southey, M. C., 1 Nov 2016, In : Breast Cancer Research and Treatment. 160, 1, p. 173-180 8 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Genome-wide measures of DNA methylation in peripheral blood and the risk of urothelial cell carcinoma: A prospective nested case-control study

Dugué, P. A., Brinkman, M. T., Milne, R. L., Wong, E. M., Fitzgerald, L. M., Bassett, J. K., Joo, J. E., Jung, C-H., Makalic, E., Schmidt, D. F., Park, D. J., Chung, J., Ta, A. D., Bolton, D. M., Lonie, A., Longano, A., Hopper, J. L., Severi, G., Saffery, R., English, D. R. & 2 others, Southey, M. C. & Giles, G. G., 6 Sep 2016, In : British Journal of Cancer. 115, 6, p. 664-673 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
16 Citations (Scopus)

Global measures of peripheral blood-derived DNA methylation as a risk factor in the development of mature B-cell neoplasms

Wong Doo, N., Makalic, E., Joo, J. E., Vajdic, C. M., Schmidt, D. F., Wong, E. M., Jung, C-H., Severi, G., Park, D. J., Chung, J., Baglietto, L., Prince, H. M., Seymour, J. F., Tam, C., Hopper, J. L., English, D. R., Milne, R. L., Harrison, S. J., Southey, M. C. & Giles, G. G., 1 Jan 2016, In : Epigenomics. 8, 1, p. 55-66 12 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Methylation of breast cancer predisposition genes in early-onset breast cancer: Australian breast cancer family registry

Scott, C. M., Joo, J. H. E., O'Callaghan, N., Buchanan, D. D., Clendenning, M., Giles, G. G., Hopper, J. L., Wong, E. M. & Southey, M. C., 1 Nov 2016, In : PLoS ONE. 11, 11, 13 p., e0165436.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
17 Citations (Scopus)

Reliability of DNA methylation measures from dried blood spots and mononuclear cells using the HumanMethylation450k BeadArray

Dugue, P. A., English, D. R., MacInnis, R. J., Jung, C-H., Bassett, J. K., Fitzgerald, L. M., Wong, E. M., Joo, J. E., Hopper, J. L., Southey, M. C., Giles, G. G. & Milne, R. L., 26 Jul 2016, In : Scientific Reports. 6, 10 p., 30317.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2015

Epigenome-wide methylation signatures in matched blood, normal breast and breast tumour specimens

Wong, E. M., 2015.

Research output: Contribution to conferencePosterOtherpeer-review

17 Citations (Scopus)

Genetic and Environmental Causes of Variation in the Difference Between Biological Age Based on DNA Methylation and Chronological Age for Middle-Aged Women

Li, S., Wong, E. M., Joo, J. H. E., Jung, C-H., Chung, J., Apicella, C., Stone, J. L., Dite, G. S., Giles, G. G., Southey, M. C. & Hopper, J. L., 1 Dec 2015, In : Twin Research and Human Genetics. 18, 6, p. 720-726 7 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Tools for translational epigenetic studies involving formalin-fixed paraffin-embedded human tissue: Applying the Infinium HumanMethyation450 Beadchip assay to large population-based studies

Wong, E. M., Joo, J. H. E., McLean, C. A., Baglietto, L., English, D. R., Severi, G., Hopper, J. L., Milne, R. L., Fitzgerald, L. M., Giles, G. G. & Southey, M. C., 6 Oct 2015, In : BMC Research Notes. 8, 1, 9 p., 543.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Erratum: Molecular Characterization and Cancer Risk Associated with BRCA1 and BRCA2 Splice Site Variants Identified in Multiple-Case Breast Cancer Families

Tesoriero, A. A., Wong, E. M., Jenkins, M. A., Hopper, J. L., Brown, M. A., Chenevix-Trench, G., Spurdle, A. B. & Southey, M. C., 1 Jan 2014, In : Human Mutation. 35, 4, p. 511 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

2013
36 Citations (Scopus)

The use of DNA from archival dried blood spots with the Infinium HumanMethylation450 array

Joo, J. H. E., Wong, E. M., Baglietto, L., Jung, C-H., Tsimiklis, H., Park, D. J., Wong, N. C., English, D. R., Hopper, J. L., Severi, G., Giles, G. G. & Southey, M. C., 15 Mar 2013, In : BMC Biotechnology. 13, 23.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2012
33 Citations (Scopus)

Identification of fifteen novel germline variants in the BRCA1 3′UTR reveals a variant in a breast cancer case that introduces a functional miR-103 target site

Brewster, B. L., Rossiello, F., French, J. D., Edwards, S. L., Wong, M., Wronski, A., Whiley, P., Waddell, N., Chen, X., Bove, B., KconFab, Hopper, J. L., John, E. M., Andrulis, I., Daly, M., Volorio, S., Bernard, L., Peissel, B., Manoukian, S., Barile, M. & 8 others, Pizzamiglio, S., Verderio, P., Spurdle, A. B., Radice, P., Godwin, A. K., Southey, M. C., Brown, M. A. & Peterlongo, P., 1 Dec 2012, In : Human Mutation. 33, 12, p. 1665-1675 11 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Using tumour pathology to identify people at high genetic risk of breast and colorectal cancers

Hopper, J. L., Jenkins, M. A., Dowty, J. G., Dite, G. S., Apicella, C., Keogh, L., Win, A. K., Young, J. P., Buchanan, D., Walsh, M. D., Rosty, C., Baglietto, L., Severi, G., Phillips, K. A., Wong, E. M., Dobrovic, A., Waring, P., Winship, I., Ramus, S. J., Giles, G. G. & 1 others, Southey, M. C., Feb 2012, In : Pathology. 44, 2, p. 89-98 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2011

Assessing gene-specific methylation using HRM-based analysis.

Wong, E. M. & Dobrovic, A. N., 2011, Methods in Molecular Biology (Methods and Protocols). Springer, Vol. 687. p. 207-217 (PCR Protocols).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

100 Citations (Scopus)

Constitutional methylation of the BRCA1 promoter is specifically associated with BRCA1 mutation-associated pathology in early-onset breast cancer

Wong, E. M., Southey, M. C., Fox, S. B., Brown, M. A., Dowty, J. G., Jenkins, M. A., Giles, G. G., Hopper, J. L. & Dobrovic, A., Jan 2011, In : Cancer Prevention Research. 4, 1, p. 23-33 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
7 Citations (Scopus)

Contribution of large genomic BRCA1 alterations to early-onset breast cancer selected for family history and tumour morphology: A report from The Breast Cancer Family Registry

Smith, L. D., Tesoriero, A. A., Wong, E. M., Ramus, S. J., O'Malley, F. P., Mulligan, A. M., Terry, M. B., Senie, R. T., Santella, R. M., John, E. M., Andrulis, I. L., Ozcelik, H., Daly, M. B., Godwin, A. K., Buys, S. S., Fox, S., Goldgar, D. E., Giles, G. G., Hopper, J. L. & Southey, M. C., 31 Jan 2011, In : Breast Cancer Research. 13, 1, R14.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
25 Citations (Scopus)

Morphological predictors of BRCA1 germline mutations in young women with breast cancer

Southey, M. C., Ramus, S. J., Dowty, J. G., Smith, L. D., Tesoriero, A. A., Wong, E. E. M., Dite, G. S., Jenkins, M. A., Byrnes, G. B., Winship, I., Phillips, K. A., Giles, G. G. & Hopper, J. L., 15 Mar 2011, In : British Journal of Cancer. 104, 6, p. 903-909 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2008
9 Citations (Scopus)

Is MSH2 a breast cancer susceptibility gene?

Wong, E. M., Tesoriero, A. A., Pupo, G. M., McCredie, M. R. E., Giles, G. G., Hopper, J. L., Mann, G. J., Goldgar, D. E. & Southey, M. C., 1 Jun 2008, In : Familial Cancer. 7, 2, p. 151-155 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2007
7 Citations (Scopus)

Prediction of BRCA1 and BRCA2 mutation status using post-irradiation assays of lymphoblastoid cell lines is compromised by inter-cell-line phenotypic variability

Lovelock, P. K., Wong, E. M., Sprung, C. N., Marsh, A., Hobson, K., French, J. D., Southey, M., Sculley, T., Pandeya, N., Brown, M. A., Cenevix-Trench, G., Spurdle, A. B. & McKay, M. J., 2007, In : Breast Cancer Research and Treatment. 104, 3, p. 257 - 266 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2006
33 Citations (Scopus)

Genetic, functional, and histopathological evaluation of two C-terminal BRCA1 missense variants

Lovelock, P. K., Healey, S., Au, W., Sum, E. Y. M., Tesoriero, A., Wong, E. M., Hinson, S., Brinkworth, R., Bekessy, A., Diez, O., Izatt, L., Solomon, E., Jenkins, M., Renard, H., Hopper, J., Waring, P., Tavtigian, S. V., Goldgar, D., Lindeman, G. J., Visvader, J. E. & 6 others, Couch, F. J., Henderson, B. R., Southey, M., Chenevix-Trench, G., Spurdle, A. B. & Brown, M. A., 1 Jan 2006, In : Journal of Medical Genetics. 43, 1, p. 74-83 10 p.

Research output: Contribution to journalArticleResearchpeer-review

122 Citations (Scopus)

Genetic and histopathologic evaluation of BRCA1 and BRCA2 DNA sequence variants of unknown clinical significance

Chenevix-Trench, G., Healey, S., Lakhani, S., Waring, P., Cummings, M., Brinkworth, R., Deffenbaugh, A. M., Burbidge, L. A., Pruss, D., Judkins, T., Scholl, T., Bekessy, A., Marsh, A., Lovelock, P., Wong, M., Tesoriero, A., Renard, H., Southey, M., Hopper, J. L., Yannoukakos, K. & 5 others, Brown, M., Easton, D., Tavtigian, S. V., Goldgar, D. & Spurdle, A. B., 15 Feb 2006, In : Cancer Research. 66, 4, p. 2019-2027 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2005
40 Citations (Scopus)

Molecular characterization and cancer risk associated with BRCA1 and BRCA2 splice site variants identified in multiple-case breast cancer families

Tesoriero, A. A., Wong, E. M., Jenkins, M. A., Hopper, J. L., Brown, M. A., Chenevix-Trench, G., Spurdle, A. B. & Southey, M. C., 1 Jan 2005, In : Human Mutation. 26, 5, 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access