Edwina McGlinn

Assoc Professor

20002019
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Research Output 2000 2019

Article

A Hox Code Defines Spinocerebellar Neuron Subtype Regionalization

Coughlan, E., Garside, V. C., Wong, S. F. L., Liang, H., Kraus, D., Karmakar, K., Maheshwari, U., Rijli, F. M., Bourne, J. & McGlinn, E., 19 Nov 2019, In : Cell Reports. 29, 8, p. 2408-2421 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
33 Citations (Scopus)

Autonomous and nonautonomous roles of hedgehog signaling in regulating limb muscle formation

Hu, J. K-H., McGlinn, E., Harfe, B. D., Kardon, G. & Tabin, C. J., 2012, In : Genes and Development. 26, 18, p. 2088 - 2102 15 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Autopodial development is selectively impaired by misexpression of chordin-like 1 in the chick limb

Allen, J. M., McGlinn, E., Hill, A. & Warman, M. L., 2013, In : Developmental Biology. 381, 1, p. 159 - 169 11 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Building a robust A-P axis

Heimberg, A. & McGlinn, E., 2012, In : Current Genomics. 13, 4, p. 278 - 288 11 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

DLC1 is unlikely to be a primary target for deletions on chromosome arm 8p22 in head and neck squamous cell carcinoma

Hewitt, C., Wilson, P., McGlinn, E., MacFarlane, G., Papageorgiou, A., Woodwards, R. T. M., Sloan, P., Gollin, S. M., Paterson, I., Parkinson, K. K., Read, A. P. & Thakker, N., 25 Jun 2004, In : Cancer Letters. 209, 2, p. 207-213 7 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Expression of the NET family member Zfp503 is regulated by hedgehog and BMP signaling in the limb

McGlinn, E., Richman, J., Metzis, V., Town, L., Butterfield, N., Wainwright, B. J. & Wicking, C., 2008, In : Developmental Dynamics. 237, 4, p. 1172 - 1182 11 p.

Research output: Contribution to journalArticleResearchpeer-review

95 Citations (Scopus)

Extended exposure to Sonic hedgehog is required for patterning the posterior digits of the vertebrate limb

Scherz, P., McGlinn, E., Nissim, S. & Tabin, C., 2007, In : Developmental Biology. 308, 2, p. 343 - 354 12 p.

Research output: Contribution to journalArticleResearchpeer-review

98 Citations (Scopus)

Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb

Mao, J., McGlinn, E., Huang, P., Tabin, C. & McMahon, A., 2009, In : Developmental Cell. 16, 4, p. 600 - 606 7 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

G551D cystic fibrosis mice exhibit abnormal regulation of inflammation in lungs and macrophages

Thomas, G. R., Costelloe, E. A., Lunn, D. P., Stacey, K. J., Delaney, S. J., Passey, R., McGlinn, E. C., McMorran, B. J., Ahadizadeh, A., Geczy, C. L., Wainwright, B. J. & Hume, D. A., 1 Apr 2000, In : Journal of Immunology. 164, 7, p. 3870-3877 8 p.

Research output: Contribution to journalArticleResearchpeer-review

130 Citations (Scopus)

Genetic polymorphism of IL-12 p40 gene in immune-mediated disease

Hall, M. A., McGlinn, E., Coakley, G., Fisher, S. A., Boki, K., Middleton, D., Kaklamani, E., Moutsopoulos, H., Loughran, T. P., Ollier, W. E. R., Panayi, G. S. & Lanchbury, J. S., 2000, In : Genes and Immunity. 1, 3, p. 219-224 6 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Inactivation of patched1 in the mouse limb has novel inhibitory effects on the chondrogenic program

Bruce, S. J., Butterfield, N. C., Metzis, V., Town, L., McGlinn, E. & Wicking, C., 3 Sep 2010, In : Journal of Biological Chemistry. 285, 36, p. 27967-27981 15 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Independent regulation of vertebral number and vertebral identity by microRNA-196 paralogs

Wong, S. F. L., Agarwal, V., Mansfield, J. H., Denans, N., Schwartz, M. G., Prosser, H. M., Pourquie, O., Bartel, D. P., Tabin, C. J. & McGlinn, E., 2015, In : Proceedings of the National Academy of Sciences. 112, 35, p. 4884 - 4893 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
61 Citations (Scopus)

In ovo application of antagomiRs indicates a role for miR-196 in patterning the chick axial skeleton through Hox gene regulation

McGlinn, E., Yekta, S., Mansfield, J., Soutschek, J., Bartel, D. & Tabin, C., 2009, In : Proceedings of the National Academy of Sciences. 106, 44, p. 18610 - 18615 6 p.

Research output: Contribution to journalArticleResearchpeer-review

75 Citations (Scopus)

Mechanistic insight into how Shh patterns the vertebrate limb

McGlinn, E. & Tabin, C., 2006, In : Current Opinion in Genetics and Development. 16, 4, p. 426 - 432 7 p.

Research output: Contribution to journalArticleOther

2 Citations (Scopus)

miR-196b target screen reveals mechanisms maintaining leukemia stemness with therapeutic potential

Meyer, S. E., Muench, D. E., Rogers, A. M., Newkold, T. J., Orr, E., O’Brien, E., Perentesis, J. P., Doench, J. G., Lal, A., Morris, P. J., Thomas, C. J., Lieberman, J., McGlinn, E., Aronow, B. J., Salomonis, N. & Grimes, H. L., 1 Sep 2018, In : Journal of Experimental Medicine. 215, 8, p. 2115-2136 22 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
187 Citations (Scopus)

miRNA malfunction causes spinal motor neuron disease

Haramati, S., Chapnik, E., Sztainberg, Y., Eilam, R., Zwang, R., Gershoni, N., McGlinn, E., Heiser, P., Wills, A-M., Wirguin, I., Rubin, L., Misawa, H., Tabin, C., Brown Jr., R., Chen, A. & Hornstein, E., 2010, In : Proceedings of the National Academy of Sciences. 107, 29, p. 13111 - 13116 6 p.

Research output: Contribution to journalArticleResearchpeer-review

38 Citations (Scopus)

Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb

Butterfield, N., Metzis, V., McGlinn, E., Bruce, S., Wainwright, B. J. & Wicking, C., 2009, In : Development. 136, 20, p. 3515 - 3524 10 p.

Research output: Contribution to journalArticleResearchpeer-review

73 Citations (Scopus)

Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb development

McGlinn, E., van Bueren, K., Fiorenza, S., Mo, R., Poh, A., Forrest, A., Soares, M., Bonaldo, M. D. F., Grimmond, S., Hui, C-C., Wainwright, B. & Wicking, C., 2005, In : Mechanisms of Development. 122, 11, p. 1218 - 1233 16 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Regulatory landscape of the hox transcriptome

Casaca, A. N. A., Hauswirth, G. M., Bildsoe, H., Mallo, M. & McGlinn, E., 1 Jan 2018, In : International Journal of Developmental Biology. 62, 11-12, p. 693-704 12 p., 62.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

Sequence variants of DLC1 in colorectal and ovarian tumours

Wilson, P. J., McGlinn, E., Marsh, A., Evans, T., Arnold, J., Wright, K., Biden, K., Young, J., Wainwright, B., Wicking, C. & Chenevix-Trench, G., 2000, In : Human Mutation. 15, 2, p. 156-165 10 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Smchd1 regulates long-range chromatin interactions on the inactive X chromosome and at Hox clusters

Jansz, N., Keniry, A., Trussart, M., Bildsoe, H., Beck, T., Tonks, I. D., Mould, A. W., Hickey, P., Breslin, K., Iminitoff, M., Ritchie, M. E., McGlinn, E., Kay, G. F., Murphy, J. M. & Blewitt, M. E., 1 Sep 2018, In : Nature Structural Biology. 25, 9, p. 766-777 12 p.

Research output: Contribution to journalArticleResearchpeer-review

238 Citations (Scopus)

The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system

Vonk, F. J., Casewell, N. R., Henkel, C. V., Heimberg, A., Jansen, H. J., McCleary, R. J. R., Kerkkamp, H. M. E., Vos, R. A., Guerreiro, I., Calvete, J. J., Wuster, W., Woods, A. E., Logan, J. M., Harrison, R. A., Castoe, T. A., de Koning, A. P. J., Pollock, D. D., Yandell, M., Calderon, D., Renjifo, C. & 16 others, Currier, R. B., Salgado, D., Pla, D., Sanz, L., Hyder, A. S., Ribeiro, J. M. C., Arntzen, J. W., van den Thillart, G. E. E. J. M., Boetzer, M., Pirovano, W., Dirks, R. P., Spaink, H. P., Duboule, D., McGlinn, E., Kini, R. M. & Richardson, M. K., 2013, In : Proceedings of the National Academy of Sciences. 110, 51, p. 20651 - 20656 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
4 Citations (Scopus)

The metalloendopeptidase gene Pitrm1 is regulated by hedgehog signaling in the developing mouse limb and is expressed in muscle progenitors

Town, L., McGlinn, E., Fiorenza, S., Metzis, V., Butterfield, N., Richman, J. & Wicking, C., 2009, In : Developmental Dynamics. 238, 12, p. 3175 - 3184 10 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

The molecular regulation of vertebrate limb patterning

Butterfield, N. C., McGlinn, E. & Wicking, C., 2010, In : Current Topics in Developmental Biology. 90, C, p. 319-341 23 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis

Pearson, H. B., McGlinn, E., Phesse, T. J., Schluter, H., Srikumar, A., Godde, N. J., Woelwer, C. B., Ryan, A. J., Phillips, W. A., Ernst, M. R., Kaur, P. & Humbert, P. O., 2015, In : Molecular Cancer. 14, 1, 16 p., 169.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)

Tmem26 is dynamically expressed during palate and limb development but is not required for embryonic survival

Town, L., McGlinn, E., Davidson, T-L., Browne, C. M., Chawengsaksophak, K., Koopman, P. A., Richman, J. M. & Wicking, C., 2011, In : PLoS ONE. 6, 9, 9 p., e25228.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Chapter (Book)
2 Citations (Scopus)

Detection of gene and protein expression in mouse embryos and tissue sections

McGlinn, E., Holzman, M. A. & Mansfield, J. H., 1 Jan 2019, Vertebrate Embryogenesis. Pelegri, F. J. (ed.). New York, NY: Humana Press, p. 183-218 36 p. (Methods in Molecular Biology; vol. 1920).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

10 Citations (Scopus)

Detection of Gene Expression in Mouse Embryos and Tissue Sections

McGlinn, E. & Mansfield, J., 2011, Methods in Molecular Biology - Vertebrate Embryogenesis. Pelegri, F. J. (ed.). 1st ed. USA: Humana Press, p. 259 - 292 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

17 Citations (Scopus)

Evolution, expression, and developmental function of Hox-embedded miRNAs

Mansfield, J. H. & McGlinn, E., 2012, MicroRNAs in Development. Hornstein, E. (ed.). 1st ed. USA: Academic Press, p. 31 - 57 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Short Survey
56 Citations (Scopus)

The role of hedgehog signalling in tumorigenesis

Wicking, C. & McGlinn, E., 8 Oct 2001, In : Cancer Letters. 173, 1, p. 1-7 7 p.

Research output: Contribution to journalShort SurveyResearchpeer-review