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Personal profile

Biography

Ed Nice obtained his Licentiate from the Royal Institute of Chemistry in London in Advanced Analytical Chemistry in 1972 and Fellowship of the Chemical Society London in 1973. He is currently Adjunct Professor at Monash University where he is Head of the Clinical Biomarker Discovery and Validation (Department of Biochemistry and Molecular Biology) and a scientific advisor to the Monash Antibody Technologies Facility (MATF), of which he was Director from 2009 - 2013. He holds a Visiting Professorship at Sichuan University’s West China Hospital and an Adjunct position at Macquarie University. Ed’s long-term research interests have been in biomarker discovery and validation, high throughput monoclonal antibody production and validation and clinical biomarker assay development, with a strong translational focus on colorectal cancer.  He has an established international reputation in the fields of HPLC, SPR biosensor analysis and proteomics, and has made significant contributions in protein and peptide micropurification. More recently he has been involved in the development of layer-by-layer nanoparticles for drug delivery using proteomic technologies.

 

Research interests

Colorectal Cancer, Biomarkers, Proteomics, Micropreparative HPLC, High THroughput Monoclonal Antibody Production, SPR, Personalised Medicine

External positions

Visiting Professor, Sichuan University

Visiting Professor, Sichuan University

Keywords

  • Colorectal Cancer
  • Biomarkers
  • Proteomics
  • HPLC
  • Surface Plasmon Resonance
  • Micropurification
  • Proteins
  • Peptides

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Projects 2010 2014

Research Output 1971 2019

Brefeldin A inhibits colorectal cancer growth by triggering Bip/Akt-regulated autophagy

Zhou, L., Gao, W., Wang, K., Huang, Z., Zhang, L., Zhang, Z., Zhou, J., Nice, E. C. & Huang, C., 1 Apr 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 4, p. 5520-5534 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Molecular insights into cancer drug resistance from a proteomics perspective

An, Y., Zhou, L., Huang, Z., Nice, E. C., Zhang, H. & Huang, C., 2019, In : Expert Review of Proteomics. 16, 5, p. 413-429 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma

Jiang, J., Zhang, L., Chen, H., Lei, Y., Zhang, T., Wang, Y., Jin, P., Lan, J., Zhou, L., Huang, Z., Li, B., Liu, Y., Gao, W., Xie, K., Zhou, L., Nice, E. C., Peng, Y., Cao, Y., Wei, Y., Wang, K. & 1 othersHuang, C., 1 Jan 2019, (Accepted/In press) In : Autophagy. 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Challenges for omics technologies in the implementation of personalized medicine

Nice, E. C., 4 Jul 2018, In : Expert Review of Precision Medicine and Drug Development. 3, 4, p. 229-231 3 p.

Research output: Contribution to journalEditorialOtherpeer-review

Open Access
File

Functional role of a novel long noncoding RNA TTN-AS1 in esophageal squamous cell carcinoma progression and metastasis

Lin, C., Zhang, S., Wang, Y., Wang, Y., Nice, E., Guo, C., Zhang, E., Yu, L., Li, M., Liu, C., Hu, L., Hao, J., Qi, W. & Xu, H., 15 Jan 2018, In : Clinical Cancer Research. 24, 2, p. 486-498 13 p.

Research output: Contribution to journalArticleResearchpeer-review