Projects per year
Personal profile
Biography
Ed Nice obtained his Licentiate from the Royal Institute of Chemistry in London in Advanced Analytical Chemistry in 1972 and Fellowship of the Chemical Society London in 1973. He is currently Adjunct Professor at Monash University where he is Head of the Clinical Biomarker Discovery and Validation (Department of Biochemistry and Molecular Biology) and a scientific advisor to the Monash Antibody Technologies Facility (MATF), of which he was Director from 2009 - 2013. He holds a Visiting Professorship at Sichuan University’s West China Hospital and an Adjunct position at Macquarie University. Ed’s long-term research interests have been in biomarker discovery and validation, high throughput monoclonal antibody production and validation and clinical biomarker assay development, with a strong translational focus on colorectal cancer. He has an established international reputation in the fields of HPLC, SPR biosensor analysis and proteomics, and has made significant contributions in protein and peptide micropurification. More recently he has been involved in the development of layer-by-layer nanoparticles for drug delivery using proteomic technologies.
Research interests
Colorectal Cancer, Biomarkers, Proteomics, Micropreparative HPLC, High THroughput Monoclonal Antibody Production, SPR, Personalised Medicine
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Visiting Professor, Sichuan University
Visiting Professor, Sichuan University
Research area keywords
- Colorectal Cancer
- Biomarkers
- Proteomics
- HPLC
- Surface Plasmon Resonance
- Micropurification
- Proteins
- Peptides
Projects
- 5 Finished
-
Melbourne and Monash integrated Proteomics Facility
Nice, E. (Primary Chief Investigator (PCI)), Bacic, A. (Chief Investigator (CI)), Mackay, C. (Chief Investigator (CI)), McClusky, J. (Chief Investigator (CI)), O'Hair, R. A. J. (Chief Investigator (CI)), Sleeman, M. (Chief Investigator (CI)), Villadangos, J. A. (Chief Investigator (CI)), Wilce, J. (Chief Investigator (CI)), Williamson, N. A. (Chief Investigator (CI)) & Bateman, J. (Partner Investigator (PI))
Australian Research Council (ARC), Monash University
1/05/13 → 31/12/14
Project: Research
-
Thermo Scientific LTO Orbitrap Elite ETD High Resolution Hybridi Mass Spectrometer
Tiganis, T., Adler, B., Andrews, Z., Bird, P., Boag, P., Borg, N., Coppel, R., Cowley, M., Jans, D., Kleifeld, O., Lackmann, M., Lithgow, T., Mitchell, C., Nice, E., Pike, R., Smith, I., Traven, A., Watt, M., Whisstock, J. & Wilce, J.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/12 → 31/12/12
Project: Research
-
Validation of a multiplexed blood based screening assay for the diagnosis of colorectal cancer
Cosgrove, L. (Primary Chief Investigator (PCI)) & Nice, E. (Chief Investigator (CI))
National Health and Medical Research Council (NHMRC) (Australia)
30/06/11 → 30/06/14
Project: Research
-
Colorectal Cancer Membrane Protein Interactomics (A Major Discriminator of Clinical Outcome)
Nice, E. (Primary Chief Investigator (PCI)) & Baker, M. A. (Partner Investigator (PI))
National Health and Medical Research Council (NHMRC) (Australia)
1/01/11 → 31/12/13
Project: Research
-
Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma
Jiang, J., Zhang, L., Chen, H., Lei, Y., Zhang, T., Wang, Y., Jin, P., Lan, J., Zhou, L., Huang, Z., Li, B., Liu, Y., Gao, W., Xie, K., Zhou, L., Nice, E. C., Peng, Y., Cao, Y., Wei, Y. & Wang, K. & 1 others, , 2020, In: Autophagy. 16, 1, p. 106-122 17 p.Research output: Contribution to journal › Article › Research › peer-review
109 Citations (Scopus) -
Brefeldin A inhibits colorectal cancer growth by triggering Bip/Akt-regulated autophagy
Zhou, L., Gao, W., Wang, K., Huang, Z., Zhang, L., Zhang, Z., Zhou, J., Nice, E. C. & Huang, C., 1 Apr 2019, In: The FASEB Journal. 33, 4, p. 5520-5534 15 p.Research output: Contribution to journal › Article › Research › peer-review
41 Citations (Scopus) -
Molecular insights into cancer drug resistance from a proteomics perspective
An, Y., Zhou, L., Huang, Z., Nice, E. C., Zhang, H. & Huang, C., 2019, In: Expert Review of Proteomics. 16, 5, p. 413-429 17 p.Research output: Contribution to journal › Review Article › Research › peer-review
22 Citations (Scopus) -
Proteomics and the microbiome: pitfalls and potential
Lin, H., He, Q.-Y., Shi, L., Sleeman, M., Baker, M. S. & Nice, E. C., 1 Jun 2019, In: Expert Review of Proteomics. 16, 6, p. 501-511 11 p.Research output: Contribution to journal › Review Article › Research › peer-review
30 Citations (Scopus) -
Challenges for omics technologies in the implementation of personalized medicine
Nice, E. C., 4 Jul 2018, In: Expert Review of Precision Medicine and Drug Development. 3, 4, p. 229-231 3 p.Research output: Contribution to journal › Editorial › Other › peer-review
Open AccessFile9 Citations (Scopus)