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Personal profile

Biography

Dragana works in the Faculty of Medicine, Nursing and Health Sciences at Monash University as a Research Fellow.

Biography

Dragana is an early career Research Fellow who has contributed important findings in models of inflammatory kidney disease, including autoimmune vasculitis, and other autoimmune diseases (rheumatoid arthritis and lupus). She has defined the critical role of several key immune mechanisms in disease pathogenesis and tested new therapies, as well as provided important findings in immunoregulation in basic immunology. The ultimate aim of her research is to find better targetted treatments for autoimmune kidney disease. Her current projects are examining the role of various costimulatory pathways and type I interferons, and testing novel cellular therapies such as tolerogenic dendritic cells and stem cells in autoimmune glomerulonephritis. In addition, she is examining the novel role of myeloperoxidase as an immune regulator.

Research area keywords

  • immunology, autoimmunity, immunotherapy, dendritic cells, kidney

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Projects 2010 2016

Research Output 2005 2019

1 Citation (Scopus)

OX40 ligand is inhibitory during the effector phase of crescentic glomerulonephritis

Odobasic, D., Ruth, A. J., Oudin, V., Kitching, A. R. & Holdsworth, S. R., 1 Mar 2019, In : Nephrology Dialysis Transplantation. 34, 3, p. 429-441 13 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

C5a receptor 1 promotes autoimmunity, neutrophil dysfunction and injury in experimental anti-myeloperoxidase glomerulonephritis

Dick, J., Gan, P. Y., Ford, S. L., Odobasic, D., Alikhan, M. A., Loosen, S. H., Hall, P., Westhorpe, C. L., Li, A., Ooi, J. D., Woodruff, T. M., Mackay, C. R., Kitching, A. R., Hickey, M. J. & Holdsworth, S. R., 1 Mar 2018, In : Kidney International. 93, 3, p. 615-625 11 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Formyl peptide receptor activation inhibits the expansion of effector T cells and synovial fibroblasts and attenuates joint injury in models of rheumatoid arthritis

Odobasic, D., Jia, Y., Kao, W., Fan, H., Wei, X., Gu, R., Ngo, D., Richard Kitching, A., Holdsworth, S. R., Morand, E. F. & Yang, Y. H., 1 Aug 2018, In : International Immunopharmacology. 61, p. 140-149 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Pathogenic role for γδ T cells in autoimmune anti-myeloperoxidase glomerulonephritis

Gan, P. Y., Fujita, T., Ooi, J. D., Alikhan, M. A., Dick, J., Shim, R., Odobasic, D., O'Sullivan, K. M., Kitching, A. R. & Holdsworth, S. R., 1 Nov 2017, In : Journal of Immunology. 199, 9, p. 3042-3050 9 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Endogenous toll-like receptor 9 regulates AKI by promoting regulatory T cell recruitment

Alikhan, M., Summers, S. A., Gan, P. Y., Chan, A., Khouri, M., Ooi, J., Ghali, J., Odobasic, D., Hickey, M. J., Kitching, A. R. & Holdsworth, S. R., 2016, In : Journal of the American Society of Nephrology. 27, 3, p. 706 - 714 9 p.

Research output: Contribution to journalArticleResearchpeer-review