Dominic Keating

ADJUNCT CLINICAL ASSOCIATE PROFESSOR, Medicine Alfred Hospital

https://orcid.org/0000-0001-6150-6927

EmailDominic.Keating@monash.edu

Research activity per year

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Personal profile

Research area keywords

Pulmonary Hypertension
Cystic Fibrosis
bronchoscopy

Network

Recent external collaboration on country level. Dive into details by clicking on the dots or

3 Active

A Phase 3, Open-label Study Evaluating the Long-term Safety of VX-445 Combination Therapy in Subjects with Cystic Fibrosis.
Keating, D.
26/11/19 → 31/10/21
Project: Research
A Phase 3, Randomized, Double-blind, Controlled Study Evaluating the Efficacy and Safety of VX-445 Combination Therapy in Subjects with Cystic Fibrosis Who Are Heterozygous for the F508del Mutation and a Gating or Residual Function Mutation (F/G and F/RF Genotypes).
Keating, D.
21/10/19 → 31/12/25
Project: Research
A Phase 3, Open-label Study Evaluating the Long-term Safety and Efficacy of VX-659 Combination therapy in Subjects with Cystic Fibrosis who are Homozygous or Heterozygous for the F508del Mutation.
Keating, D.
10/08/18 → 10/08/23
Project: Research

19 Article
2 Chapter (Book)
2 Letter

Antibiotic exposure and interpersonal variance mask the effect of ivacaftor on respiratory microbiota composition
Peleg, A. Y., Choo, J. M., Langan, K. M., Edgeworth, D., Keating, D., Wilson, J., Rogers, G. B. & Kotsimbos, T., 1 Jan 2018, In : Journal of Cystic Fibrosis. 17, 1, p. 50-56 7 p.
Research output: Contribution to journal › Article › Research › peer-review

17 Citations (Scopus)
Subclinical Left Ventricular Dysfunction is Influenced by Genotype Severity in Patients with Cystic Fibrosis
Pallin, M., Keating, D., Kaye, D. M., Kotsimbos, T. & Wilson, J. W., 1 Aug 2018, In : Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine. 12, 5 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

4 Citations (Scopus)
Survival of Idiopathic Pulmonary Arterial Hypertension Patients in the Modern Era in Australia and New Zealand
on behalf of PHSANZ Registry, 1 Nov 2018, In : Heart Lung and Circulation. 27, 11, p. 1368-1375 8 p.
Research output: Contribution to journal › Article › Research › peer-review

14 Citations (Scopus)
VX-445-tezacaftor-ivacaftor in patients with cystic fibrosis and one or two Phe508del alleles
Keating, D., Marigowda, G., Burr, L., Daines, C., Mall, M. A., McKone, E. F., Ramsey, B. W., Rowe, S. M., Sass, L. A., Tullis, E., McKee, C. M., Moskowitz, S. M., Robertson, S., Savage, J., Simard, C., Van Goor, F., Waltz, D., Xuan, F., Young, T. & Taylor-Cousar, J. L., 25 Oct 2018, In : The New England Journal of Medicine. 379, 17, p. 1612-1620 9 p.
Research output: Contribution to journal › Article › Research › peer-review

199 Citations (Scopus)
Improvement in exercise duration, lung function and well-being in G551D-cystic fibrosis patients: a double-blind, placebo-controlled, randomized, cross-over study with ivacaftor treatment
Edgeworth, D., Keating, D., Ellis, M., Button, B., Williams, E., Clark, D., Tierney, A., Heritier, S., Kotsimbos, T. & Wilson, J., 1 Aug 2017, In : Clinical Science. 131, 15, p. 2037-2045 9 p.
Research output: Contribution to journal › Article › Research › peer-review

25 Citations (Scopus)