Projects per year
Personal profile
Biography
Diana Hansen completed her PhD studies at the University of Buenos Aires in the context of a collaborative program between the National Institute of Parasitology in Argentina and the National Veterinary Institute in Uppsala, Sweden. She turned to malaria research during her postdoctoral training at the Walter and Eliza Hall Institute, Melbourne, Australia, where she established an internationally recognised program to investigate inflammatory responses responsible for the induction of severe malaria. Diana is now a Professor of Microbiology and Co-Head of the Infection Discovery Program at the Monash Biomedicine Discovery Institute, Monash University. Diana’s main current research focuses on finding solutions to tackle two devastating mosquito-borne infectious diseases, malaria and dengue fever, which together account for 600 million clinical cases worldwide annually. In 2020, Diana also turned into COVID-19 research, setting up clinical studies in Australia and overseas. Her main interests include understanding mechanisms regulating pathogenesis and induction of immunity to these infectious diseases and she is pursuing those goals using pre-clinical infection models as well as applying systems immunology approaches to clinical studies in endemic areas. Diana’s has received funding from the NHMRC, e-ASIA, the Department of Foreign Affairs and Trade and the Australian Academy of Science.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- malaria
- Dengue viral infection
- immune responses
Collaborations and top research areas from the last five years
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Integrated systems immunology approach for identification of biomarkers of dengue hemorrhagic fever
1/05/24 → 1/05/25
Project: Research
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Uncovering the burden of asymptomatic malaria: dissecting immune responses to infection to overcome immunosuppression and improve vaccination strategies
Hansen, D., Stanisic, D. I., Good, M., Shi, W., Bowden, R., Tsuboi, T., Takashima, E., Noviyanti, R., Hoffman, S. L. & Wibowo, I.
1/01/24 → 31/12/26
Project: Research
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Identification of molecular and cellular pathways predicting susceptibility or resistance to severe dengue fever
Hansen, D., Shi, W., Yu, D., Sasmono, R. T., Morita, K. & Moi, M. L.
1/01/21 → 31/12/23
Project: Research
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The impact of Clostridium difficile infection and the host immune response on colonic homeostasis and regeneration.
Lyras, D., Abud, H., Clevers, H. C. & Hansen, D.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/16 → 31/12/19
Project: Research
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An immunohistochemical atlas of necroptotic pathway expression
Chiou, S., Al-Ani, A. H., Pan, Y., Patel, K. M., Kong, I. Y., Whitehead, L. W., Light, A., Young, S. N., Barrios, M., Sargeant, C., Rajasekhar, P., Zhu, L., Hempel, A., Lin, A., Rickard, J. A., Hall, C., Gangatirkar, P., Yip, R. K. H., Cawthorne, W., Jacobsen, A. V., & 19 others , 15 Jul 2024, In: EMBO Molecular Medicine. 16, 7, p. 1717 - 1749 33 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access8 Citations (Scopus) -
Integrated systems immunology approach identifies impaired effector T cell memory responses as a feature of progression to severe dengue fever
Ioannidis, L. J., Studniberg, S. I., Eriksson, E. M., Suwarto, S., Denis, D., Liao, Y., Shi, W., Garnham, A. L., Sasmono, R. T. & Hansen, D. S., 13 Apr 2023, In: Journal of Biomedical Science. 30, 1, 21 p., 24.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Bezlotoxumab prevents extraintestinal organ damage induced by Clostridioides difficile infection
Mileto, S. J., Hutton, M. L., Walton, S. L., Das, A., Ioannidis, L. J., Ketagoda, D., Quinn, K. M., Denton, K. M., Hansen, D. S. & Lyras, D., 1 Jan 2022, In: Gut Microbes. 14, 1, 18 p., e2117504.Research output: Contribution to journal › Article › Research › peer-review
Open Access10 Citations (Scopus) -
CyTOF mass cytometry analysis of human memory CD4+ T cells and memory B cells
Ioannidis, L. J., Mitchell, A. J., Zheng, T. & Hansen, D. S., 17 Jun 2022, In: STAR Protocols. 3, 2, 15 p., 101269.Research output: Contribution to journal › Article › Other › peer-review
Open Access3 Citations (Scopus) -
Molecular profiling reveals features of clinical immunity and immunosuppression in asymptomatic P. falciparum malaria
Studniberg, S. I., Ioannidis, L. J., Utami, R. A. S., Trianty, L., Liao, Y., Abeysekera, W., Li-Wai-Suen, C. S. N., Pietrzak, H. M., Healer, J., Puspitasari, A. M., Apriyanti, D., Coutrier, F., Poespoprodjo, J. R., Kenangalem, E., Andries, B., Prayoga, P., Sariyanti, N., Smyth, G. K., Cowman, A. F., Price, R. N., & 4 others , Apr 2022, In: Molecular Systems Biology. 18, 4, 25 p., e10824.Research output: Contribution to journal › Article › Research › peer-review
Open Access13 Citations (Scopus)