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Research Output 2003 2019

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2019

AKT signaling promotes DNA damage accumulation and proliferation in polycystic kidney disease

Conduit, S. E., Davies, E. M., Ooms, L. M., Gurung, R., Mcgrath, M. J., Hakim, S., Cottle, D. L., Smyth, I. M., Dyson, J. M. & Mitchell, C. A., 18 Oct 2019, (Accepted/In press) In : Human Molecular Genetics.

Research output: Contribution to journalArticleResearchpeer-review

CBE1 Is a Manchette- and Mitochondria-Associated Protein With a Potential Role in Somatic Cell Proliferation

Pleuger, C., Lehti, M. S., Cooper, M., O'Connor, A. E., Merriner, D. J., Smyth, I. M., Cottle, D. L., Fietz, D., Bergmann, M. & O'Bryan, M. K., 1 Nov 2019, In : Endocrinology. 160, 11, p. 2573-2586 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2018
3 Citations (Scopus)

Loss of GRHL3 leads to TARC/CCL17-mediated keratinocyte proliferation in the epidermis

Goldie, S. J., Cottle, D. L., Tan, F. H., Roslan, S., Srivastava, S., Brady, R., Partridge, D. D., Auden, A., Smyth, I. M., Jane, S. M., Dworkin, S. & Darido, C., 19 Oct 2018, In : Cell Death and Disease. 9, 11, 12 p., 1072.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2015
12 Citations (Scopus)

Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis

Cottle, D. L., Ursino, G. M. A., Ip, S. C. L., Jones, L. K., Ditommaso, T. M., Hacking, D. F., Mangan, N. E., Mellett, N. A., Henley, K. J., Sviridov, D., Nold-Petry, C. A., Nold, M. F., Meikle, P. J., Kile, B. T. & Smyth, I. M., 2015, In : Human Molecular Genetics. 24, 2, p. 436-449 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
33 Citations (Scopus)

INPP5E interacts with AURKA, linking phosphoinositide signaling to primary cilium stability

Plotnikova, O., Seo, S., Cottle, D. L., Conduit, S. E., Hakim, S., Dyson, J. M., Mitchell, C. A. & Smyth, I. M., 2015, In : Journal of Cell Science. 128, 2, p. 364-372 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
21 Citations (Scopus)

The androgen receptor antagonizes Wnt/beta-Catenin signaling in epidermal stem cells

Kretzschmar, K., Cottle, D. L., Schweiger, P. J. & Watt, F. M., 2015, In : Journal of Investigative Dermatology. 135, 11, p. 2753 - 2763 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2014
27 Citations (Scopus)

BLIMP1 is required for postnatal epidermal homeostasis but does not define a sebaceous gland progenitor under steady-state conditions

Kretzschmar, K., Cottle, D. L., Donati, G., Chiang, M-F., Quist, S. R., Gollnick, H., Natsuga, K., Lin, K-I. & Watt, F. M., 2014, In : Stem Cell Reports. 3, 4, p. 620 - 633 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
12 Citations (Scopus)

Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse

Ditommaso, T. M., Jones, L. K., Cottle, D. L., Gerdin, A-K., Vancollie, V. E., Watt, F. M., Ramirez-Solis, R., Bradley, A., Steel, K. P., Sundberg, J. P., White, J. K. & Smyth, I. M., 2014, In : PLoS Genetics. 10, 10, p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
16 Citations (Scopus)

Keratin 76 is required for tight junction function and maintenance of the skin barrier

Ditommaso, T. M., Cottle, D. L., Pearson, H. B., Schluter, H., Kaur, P., Humbert, P. O. & Smyth, I. M., 2014, In : PLoS Genetics. 10, 10, p. 1 - 13 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2013
30 Citations (Scopus)

C-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis

Cottle, D. L., Kretzschmar, K., Schweiger, P. J., Quist, S. R., Gollnick, H. P., Natsuga, K., Aoyagi, S. & Watt, F. M., 2013, In : Cell Reports. 3, 2, p. 427-441 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
8 Citations (Scopus)

Regulation of PDGFC signalling and extracellular matrix composition by FREM1 in mice

Wiradjaja, F., Cottle, D. L., Jones, L. K. & Smyth, I. M., 2013, In : Disease Models and Mechanisms. 6, 6, p. 1426 - 1433 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
37 Citations (Scopus)

Regulation of the transcriptional coactivator FHL2 licenses activation of the androgen receptor in castrate-resistant prostate cancer

Mcgrath, M. J., Binge, L. C., Sriratana, A., Wang, H., Robinson, P. A., Pook, D. W., Fedele, C. G., Brown, S., Dyson, J. M., Cottle, D. L., Cowling, B. S., Niranjan, B., Risbridger, G. P. & Mitchell, C. A., 2013, In : Cancer Research. 73, 16, p. 5066 - 5079 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2011
60 Citations (Scopus)

Four and a half LIM protein 1 gene mutations cause four distinct human myopathies: A comprehensive review of the clinical, histological and pathological features

Cowling, B., Cottle, D. L., Wilding, B., D'Arcy, C. E., Mitchell, C. A. & Mcgrath, M. J., 2011, In : Neuromuscular Disorders. 21, 4, p. 237 - 251 15 p.

Research output: Contribution to journalArticleResearchpeer-review

2010
26 Citations (Scopus)

Dose and context dependent effects of Myc on epidermal stem cell proliferation and differentiation

Berta, M. A., Baker, C. M., Cottle, D. L. & Watt, F. M., Jan 2010, In : EMBO Molecular Medicine. 2, 1, p. 16-25 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2009
14 Citations (Scopus)

SLIMMER (FHL1B/KyoT3) interacts with the proapoptotic protein Siva-1 (CD27BP) and delays skeletal myoblast apoptosis

Cottle, D. L., Mcgrath, M. J., Wilding, B. R., Cowling, B. S., Kane, J. M., D'Arcy, C. E., Holdsworth, M., Hatzinisiriou, I., Prescott, M., Brown, S. & Mitchell, C. A., 2009, In : Journal of Biological Chemistry. 284, 39, p. 26964 - 26977 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2008
80 Citations (Scopus)

Identifi cation of FHL1 as a regulator of skeletal muscle mass: Implications for human myopathy

Cowling, B. S., Mcgrath, M. J., Nguyen, M-A., Cottle, D., Kee, A. J., Brown, S., Schessl, J., Zou, Y., Joya, J., Bonnemann, C. G., Hardeman, E. C. & Mitchell, C. A., 2008, In : Journal of Cell Biology. 183, 6, p. 1033 - 1048 16 p.

Research output: Contribution to journalArticleResearchpeer-review

111 Citations (Scopus)

Proteomic identification of FHL1 as the protein mutated in human reducing body myopathy

Schessl, J., Zou, Y., Mcgrath, M. J., Cowling, B. S., Maiti, B., Chin, S. S., Sewry, C., Battini, R., Hu, Y., Cottle, D., Rosenblatt, M., Spruce, L., Ganguly, A., Kirschner, J., Judkins, A. R., Golden, J. A., Goebel, H-H., Muntoni, F., Flanigan, K. M., Mitchell, C. A. & 1 others, Bonnemann, C. G., 2008, In : Journal of Clinical Investigation. 118, 3, p. 904 - 912 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2007
33 Citations (Scopus)

FHL3 binds MyoD and negatively regulates myotube formation

Cottle, D., Mcgrath, M. J., Cowling, B. S., Coghill, I. D., Brown, S. & Mitchell, C. A., 2007, In : Journal of Cell Science. 120, Pt 8, p. 1423 - 1435 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2006
84 Citations (Scopus)

Four and a half LIM protein 1 binds myosin-binding protein C and regulates myosin filament formation and sarcomere assembly

Mcgrath, M. J., Cottle, D. L., Nguyen, M-A., Dyson, J. M., Coghill, I. D., Robinson, P. A., Holdsworth, M., Hardeman, E. C., Mitchell, C. A., Brown, S. & Cowling, B. S., 2006, In : Journal of Biological Chemistry. 281, 11, p. 7666 - 7683 18 p.

Research output: Contribution to journalArticleResearchpeer-review

2003
64 Citations (Scopus)