Denise Wootten

Projects

Projects per year 2013 2019 2021 2023 2028

• 10 Finished
• 11 Active

Projects per year

Search results

• Active

  Mechanistic understanding of biased agonism and dimerisation for co-targeting incretin receptors for metabolic diseases

  Wootten, D.

  1/01/24 → 31/12/28

  Project: Research

• Structural characterization of GLP-1 peptide agonists in complex with GLP-1R and amylin-receptor antibody in complex with amylin receptors

  Wootten, D., Sexton, P., Zhang, C., Belousoff, M., Reedtz-Runge, S. & Glendorf, T.

  1/10/23 → 31/12/24

  Project: Research

• Structure determination of GPCR heteromers

  Sexton, P., Wootten, D., Belousoff, M. & Shepard, R.

  27/07/23 → 26/07/27

  Project: Research

• The physiological importance of GLP-1R and GIPR dimerisation

  Wootten, D. & Hutchinson, D.

  Australian Research Council (ARC), Monash University – Internal School Contribution

  2/01/23 → 1/01/26

  Project: Research

• Structure and dynamics of class B1 G protein coupled receptors

  Wootten, D., Belousoff, M. & Josephs, T.

  Australian Research Council (ARC), Monash University – Internal School Contribution

  2/01/23 → 1/01/26

  Project: Research

• Development of approaches for inactive, antagonist bound GPCR structures determination

  Wootten, D., Sexton, P., Belousoff, M., Johnson, R. & Han, S.

  22/02/22 → 21/02/26

  Project: Research

• Cryo‐EM structure determination of G protein‐coupled receptors

  Sexton, P., Wootten, D., Belousoff, M., Nar, H., Weichert, D., Ebenhoch, R., Ou, Q. & Lee, D.

  21/09/21 → 21/09/25

  Project: Research

• Optimisation of GPCR expression, purification and structure determination

  Sexton, P., Wootten, D., Belousoff, M., Tovey, J. C., Williams, P. & Apelbaum, A.

  7/04/21 → 6/04/25

  Project: Research

• Development of approaches for orphan GPCR structure determination

  Sexton, P., Wootten, D., Belousoff, M., Zhang, C., Russell, I. C. & Flocco, M.

  7/04/21 → 6/04/25

  Project: Research

• ARC Industrial Transformation Training Centre for Cryo-Electron Microscopy of Membrane Proteins for Drug Discovery

  Sexton, P., Rouiller, I., Wootten, D., van Oijen, A., Parker, M. W., Lucet, I., Griffin, M. D. W., Adams, D. J., Czabotar, P. E., Flocco, M., Han, S., Shepherd, R., Ciferri, C., Williams, P. A., Brown, D., Schreuder, H., Reedtz-Runge, S., Drinkwater, C., Howard, B. L., Betigeri, G., Pryor, E. & How, J.

  Boehringer Ingelheim (Germany), AstraZeneca (United Kingdom)

  23/03/21 → 22/03/26

  Project: Research

• Molecular control of efficacy at glucagon family of receptors

  Wootten, D. & Wu, B.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/20 → 31/12/24

  Project: Research