Projects per year
Search results
-
Active
Mechanistic understanding of biased agonism and dimerisation for co-targeting incretin receptors for metabolic diseases
1/01/24 → 31/12/28
Project: Research
-
Structure determination of GPCR heteromers
Sexton, P., Wootten, D., Belousoff, M. & Shepard, R.
27/07/23 → 26/07/27
Project: Research
-
Development of approaches for inactive, antagonist bound GPCR structures determination
Wootten, D., Sexton, P., Belousoff, M., Johnson, R. & Han, S.
22/02/22 → 21/02/26
Project: Research
-
Cryo‐EM structure determination of G protein‐coupled receptors
Sexton, P., Wootten, D., Belousoff, M., Nar, H., Weichert, D., Ebenhoch, R., Ou, Q. & Lee, D.
21/09/21 → 21/09/25
Project: Research
-
Optimisation of GPCR expression, purification and structure determination
Sexton, P., Wootten, D., Belousoff, M., Tovey, J. C., Williams, P. & Apelbaum, A.
7/04/21 → 6/04/25
Project: Research
-
Development of approaches for orphan GPCR structure determination
Sexton, P., Wootten, D., Belousoff, M., Zhang, C., Russell, I. C. & Flocco, M.
7/04/21 → 6/04/25
Project: Research
-
ARC Industrial Transformation Training Centre for Cryo-Electron Microscopy of Membrane Proteins for Drug Discovery
Sexton, P., Rouiller, I., Wootten, D., van Oijen, A., Parker, M. W., Lucet, I., Griffin, M. D. W., Adams, D. J., Czabotar, P. E., Flocco, M., Han, S., Shepherd, R., Ciferri, C., Williams, P. A., Brown, D., Schreuder, H., Reedtz-Runge, S., Drinkwater, C., Howard, B. L., Betigeri, G., Pryor, E., How, J. & Christopoulos, T.
Boehringer Ingelheim (Germany), AstraZeneca (United Kingdom)
23/03/21 → 23/03/27
Project: Research
-
Finished
Structural characterization of GLP-1 peptide agonists in complex with GLP-1R and amylin-receptor antibody in complex with amylin receptors
Wootten, D., Sexton, P., Zhang, C., Belousoff, M., Reedtz-Runge, S. & Glendorf, T.
1/10/23 → 31/12/24
Project: Research
-
Cryo correlative Focused Ion Beam, a new frontier in structural biology
Hanssen, E. G., Ghosal, D., McFadden, G. I., Rouiller, I., Parker, M. W., Ivanova, E. P., Wootten, D., Belousoff, M., Lucet, I., Czabotar, P. E. & Bouwer, J.
17/04/23 → 16/04/24
Project: Research
-
Molecular control of efficacy at glucagon family of receptors
Wootten, D. & Wu, B.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/20 → 31/12/24
Project: Research
-
A structural understanding of calcitonin gene-related peptide and adrenomedullin function
Wootten, D., Hay, D. & Liang, L.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/19 → 31/12/23
Project: Research
-
The structural basis for biased agonism at the glucagon-like peptide-1 receptor
Wootten, D. & Miller, L.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/17 → 31/12/20
Project: Research
-
Understanding the structural basis for Family B G protein-coupled receptor function
Sexton, P., Furness, S., Kobilka, B. & Wootten, D.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/14 → 31/12/16
Project: Research
-
Understanding the Physiological Role of Ligand Bias Signalling at the Glucagon-Like Peptide-1 Receptor
Sexton, P., Christopoulos, A., Dodson Michael, M., Sloop, K., Willard, F. & Wootten, D.
11/12/13 → 10/12/15
Project: Research