20102018
If you made any changes in Pure these will be visible here soon.

Personal profile

Keywords

  • Malaria
  • Structural Biology

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2010 2018

FusC, a member of the M16 protease family acquired by bacteria for iron piracy against plants

Grinter, R., Hay, I. D., Song, J., Wang, J., Teng, D., Dhanesakaran, V., Wilksch, J. J., Davies, M. R., Littler, D., Beckham, S. A., Henderson, I. R., Strugnell, R. A., Dougan, G. & Lithgow, T., 2 Aug 2018, In : PLoS Biology. 16, 8, 21 p., e2006026.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Structure-function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteins

Littler, D. R., Ang, S. Y., Moriel, D. G., Kocan, M., Kleifeld, O., Johnson, M. D., Tran, M. T., Paton, A. W., Paton, J. C., Summers, R. J., Schembri, M. A., Rossjohn, J. & Beddoe, T., 8 Sep 2017, In : Journal of Biological Chemistry. 292, 36, p. 15143-15158 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Antimalarial activity of novel 4-cyano-3-methylisoquinoline inhibitors against Plasmodium falciparum: Design, synthesis and biological evaluation

Buskes, M. J., Harvey, K. L., Richards, B. J., Kalhor, R., Christoff, R. M., Gardhi, C. K., Littler, D. R., Cope, E. D., Prinz, B., Weiss, G. E., O'Brien, N. J., Crabb, B. S., Deady, L. W., Gilson, P. R. & Abbott, B. M., 22 Apr 2016, In : Organic and Biomolecular Chemistry. 14, 20, p. 4617-4639 23 p.

Research output: Contribution to journalArticleResearchpeer-review

Crystal structure of fuculose aldolase from the Antarctic psychrophilic yeast Glaciozyma antarctica PI12

Jaafar, N. R., Littler, D., Beddoe, T., Rossjohn, J., Illias, R. M., Mahadi, N. M., Mackeen, M. M., Murad, A. M. A. & Bakar, F. D. A., Nov 2016, In : Acta Crystallographica. Section F: Structural Biology Communications. F72, 11, p. 831-839 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Disrupting the allosteric interaction between the Plasmodium falciparum cAMP-dependent kinase and its regulatory subunit

Littler, D. R., Bullen, H. E., Harvey, K. L., Beddoe, T., Crabb, B. S., Rossjohn, J. & Gilson, P. R., 2 Dec 2016, In : Journal of Biological Chemistry. 291, 49, p. 25375-25386 12 p.

Research output: Contribution to journalArticleResearchpeer-review