20042022
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Research Output 2004 2017

2017
8 Citations (Scopus)

Cyclin A2 modulates kinetochore-microtubule attachment in meiosis II

Zhang, Q-H., Yuen, W. S., Adhikari, D., Flegg, J. A., FitzHarris, G., Conti, M., Sicinski, P., Nabti, I., Marangos, P. & Carroll, J., 17 Aug 2017, In : Journal of Cell Biology. 216, 10, p. 3133-3143 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

MASTL is essential for anaphase entry of proliferating primordial germ cells and establishment of female germ cells in mice

Risal, S., Zhang, J., Adhikari, D., Liu, X., Shao, J., Hu, M., Busayavalasa, K., Tu, Z., Chen, Z., Kaldis, P. & Liu, K., 7 Feb 2017, In : Cell Discovery. 3, 14 p., 16052.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2016
5 Citations (Scopus)

Animal models for studying the in vivo functions of cell cycle CDKs

Risal, S., Adhikari, D. & Liu, K., 2016, In : Methods in Molecular Biology. 1336, p. 155-166 12 p.

Research output: Contribution to journalArticleOtherpeer-review

7 Citations (Scopus)

Cdk2 catalytic activity is essential for meiotic cell division in vivo

Chauhan, S., Diril, M. K., Lee, J. H. S., Bisteau, X., Manoharan, V., Adhikari, D., Ratnacaram, C. K., Janela, B., Noffke, J., Ginhoux, F., Coppola, V., Liu, K., Tessarollo, L. & Kaldis, P., Sep 2016, In : Biochemical Journal. 473, 18, p. 2783-2798 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
11 Citations (Scopus)

Inhibitory phosphorylation of Cdk1 mediates prolonged prophase I arrest in female germ cells and is essential for female reproductive lifespan

Adhikari, D., Busayavalasa, K., Zhang, J., Hu, M., Risal, S., Bayazit, M. B., Singh, M., Diril, M. K., Kaldis, P. & Liu, K., 1 Nov 2016, In : Cell Research. 26, 11, p. 1212-1225 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2015
2 Citations (Scopus)

Mastl/PP2A regulate Cdk1 in ooycte maturation

Adhikari, D., Liu, K. & Kaldis, P., 2015, In : Oncotarget. 6, 22, p. 18734-18735 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

2014
17 Citations (Scopus)

Mastl is required for timely activation of APC/C in meiosis I and Cdk1 reactivation in meiosis II

Adhikari, D., Diril, M. K., Busayavalasa, K., Risal, S., Nakagawa, S., Lindkvist, R., Shen, Y., Coppola, V., Tessarollo, L., Kudo, N. R., Kaldis, P. & Liu, K., 29 Sep 2014, In : Journal of Cell Biology. 206, 7, p. 843-853 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
14 Citations (Scopus)

mTORC1 signaling in oocytes is dispensable for the survival of primordial follicles and for female fertility

Gorre, N., Adhikari, D., Lindkvist, R., Brännström, M., Liu, K. & Shen, Y., 22 Oct 2014, In : PLoS ONE. 9, 10, 5 p., e110491.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
49 Citations (Scopus)

The regulation of maturation promoting factor during prophase I arrest and meiotic entry in mammalian oocytes

Adhikari, D. & Liu, K., 25 Jan 2014, In : Molecular and Cellular Endocrinology. 382, 1, p. 480-487 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2013
8 Citations (Scopus)

Combating ovarian aging depends on the use of existing ovarian follicles, not on putative oogonial stem cells

Zhang, H., Adhikari, D., Zheng, W. & Liu, K., Dec 2013, In : Reproduction. 146, 6

Research output: Contribution to journalReview ArticleResearchpeer-review

3 Citations (Scopus)

In vitro activation of dormant follicles for fertility preservation

Adhikari, D., 2013, Oocyte Biology in Fertility Preservation. Kim, S. S. (ed.). New York NY USA: Springer, Vol. 761. p. 29-42 14 p. (Advances in Experimental Medicine and Biology; vol. 761).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

34 Citations (Scopus)

Pharmacological Inhibition of mTORC1 Prevents Over-Activation of the Primordial Follicle Pool in Response to Elevated PI3K Signaling

Adhikari, D., Risal, S., Liu, K. & Shen, Y., 17 Jan 2013, In : PLoS ONE. 8, 1, e53810.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Regulation of quiescence and activation of oocyte growth in primordial follicles

Adhikari, D. & Liu, K., 1 Jan 2013, Oogenesis. Coticchio, G., Albertini, D. F. & Santis, L. D. (eds.). London UK: Springer-Verlag London Ltd., p. 49-62 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

2012
57 Citations (Scopus)

Cdk1, but not Cdk2, is the sole Cdk that is essential and sufficient to drive resumption of meiosis in mouse oocytes

Adhikari, D., Zheng, W., Shen, Y., Gorre, N., Ning, Y., Halet, G., Kaldis, P. & Liu, K., Jun 2012, In : Human Molecular Genetics. 21, 11, p. 2476-2484 9 p., dds061.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Cdk1 drives meiosis and mitosis through two different mechanisms

Adhikari, D., Liu, K. & Shen, Y., 1 Aug 2012, In : Cell Cycle. 11, 15, p. 2763-2764 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

127 Citations (Scopus)

Experimental evidence showing that no mitotically active female germline progenitors exist in postnatal mouse ovaries

Zhang, H., Zheng, W., Shen, Y., Adhikari, D., Ueno, H. & Liu, K., 31 Jul 2012, In : Proceedings of the National Academy of Sciences. 109, 31, p. 12580-12585 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
48 Citations (Scopus)

The safe use of a PTEN inhibitor for the activation of dormant mouse primordial follicles and generation of fertilizable eggs

Adhikari, D., Gorre, N., Risal, S., Zhao, Z., Zhang, H., Shen, Y. & Liu, K., 27 Jun 2012, In : PLoS ONE. 7, 6, e39034.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2010
53 Citations (Scopus)

Genetically modified mouse models for premature ovarian failure (POF)

Jagarlamudi, K., Reddy, P., Adhikari, D. & Liu, K., 5 Feb 2010, In : Molecular and Cellular Endocrinology. 315, 1-2, p. 1-10 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

42 Citations (Scopus)

mTOR signaling in the control of activation of primordial follicles

Adhikari, D. & Liu, K., 1 May 2010, In : Cell Cycle. 9, 9, p. 1673-1674 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

Myocarditis and mobitz type I heart block following wasp sting

Vishwanath, P., Adhikari, D., Akila, Poudel, R., Poudel, K., Pillay, V. V. & Menezes, R. G., 9 Jul 2010, In : Internet Journal of Cardiology. 8, 1

Research output: Contribution to journalArticleResearchpeer-review

2009
106 Citations (Scopus)

Disruption of Tsc2 in oocytes leads to overactivation of the entire pool of primordial follicles

Adhikari, D., Flohr, G., Gorre, N., Shen, Y., Yang, H., Lundin, E., Lan, Z., Gambello, M. J. & Liu, K., 20 Oct 2009, In : Molecular Human Reproduction. 15, 12, p. 765-770 6 p., gap092.

Research output: Contribution to journalArticleResearchpeer-review

183 Citations (Scopus)

Molecular mechanisms underlying the activation of mammalian primordial follicles

Adhikari, D. & Liu, K., Aug 2009, In : Endocrine Reviews. 30, 5, p. 438-464 27 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

70 Citations (Scopus)

Oocyte-specific deletion of Pten in mice reveals a stage-specific function of PTEN/PI3K signaling in oocytes in controlling follicular activation

Jagarlamudi, K., Liu, L., Adhikari, D., Reddy, P., Idahl, A., Ottander, U., Lundin, E. & Liu, K., 9 Jul 2009, In : PLoS ONE. 4, 7, e6186.

Research output: Contribution to journalArticleResearchpeer-review

135 Citations (Scopus)

PDK1 signaling in oocytes controls reproductive aging and lifespan by manipulating the survival of primordial follicles

Reddy, P., Adhikari, D., Zheng, W., Liang, S., Hämäläinen, T., Tohonen, V., Ogawa, W., Noda, T., Volarevic, S., Huhtaniemi, I. & Liu, K., 2009, In : Human Molecular Genetics. 18, 15, p. 2813-2824 12 p.

Research output: Contribution to journalArticleResearchpeer-review

155 Citations (Scopus)

Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles

Adhikari, D., Zheng, W., Shen, Y., Gorre, N., Hämäläinen, T., Cooney, A. J., Huhtaniemi, I., Lan, Z. J. & Liu, K., 20 Oct 2009, In : Human Molecular Genetics. 19, 3, p. 397-410 14 p., ddp483.

Research output: Contribution to journalArticleResearchpeer-review

2008
14 Citations (Scopus)

A study of oxidative stress, antioxidant status and lipid profile in diabetic patient in the western region of Nepal.

Maharjan, B. R., Jha, J. C., Adhikari, D., Vishwanath, P., Baxi, J., Alurkar, V. M. & Singh, P. P., 1 Jan 2008, In : Kathmandu University Medical Journal. 6, 1, p. 16-22 7 p.

Research output: Contribution to journalArticleResearchpeer-review

424 Citations (Scopus)

Oocyte-specific deletion of pten causes premature activation of the primordial follicle pool

Reddy, P., Liu, L., Adhikari, D., Jagarlamudi, K., Rajareddy, S., Shen, Y., Du, C., Tang, W., Hämäläinen, T., Peng, S. L., Lan, Z. J., Cooney, A. J., Huhtaniemi, I. & Liu, K., 1 Feb 2008, In : Science. 319, 5863, p. 611-613 3 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Oxidative stress, antioxidant status and lipid profile in ischemic heart disease patients from western region of Nepal.

Maharjan, B. R., Jha, J. C., Adhikari, D., Akila, Risal, S., Alurkar, V. M. & Singh, P. P., 1 Mar 2008, In : Nepal Medical College journal : NMCJ. 10, 1, p. 20-24 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2007
2 Citations (Scopus)

Biotechnology in forensic science: the revolution continues.

Pillay, V. V., Menezes, R. G., Krishnaprasad, R., Pillay, M., Lobo, S. W., Adhikari, D., Vishwanath, P., Bhat, N. B., Kanchan, T. & Vasudevan, D. M., 1 Mar 2007, In : Nepal Medical College journal : NMCJ. 9, 1, p. 57-62 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2006
1 Citation (Scopus)

Epidemiology and etiopathogenesis of urinary calculi in western Nepal (Pokhara).

Pandeya, D. R., Adhikari, D., Risal, S., Baxi, J. & Singh, P. P., 1 Sep 2006, In : Nepal Medical College journal : NMCJ. 8, 3, p. 190-193 4 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Oxidative stress and antioxidant status in cardiovascular diseases in population of western Nepal

Risal, S., Adhikari, D., Alurkar, V. M. & Singh, P. P., 1 Jul 2006, In : Kathmandu University Medical Journal. 4 NO. 3, 15, p. 271-274 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Spectrum of stones composition: a chemical analysis of renal stones of patients visiting NMCTH.

Risal, S., Risal, P., Pandeya, D. R., Adhikari, D., Bhattachraya, C. S., Singh, P. P. & Shrestha, M. L., 1 Dec 2006, In : Nepal Medical College journal : NMCJ. 8, 4, p. 263-265 3 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Vitamin C status in cancer patients and healthy subjects from the local population of Pokhara

Adhikari, D., Baxi, J., Nagamma, T., Azhari, S. & Singh, P. P., 1 Jul 2006, In : Kathmandu University Medical Journal. 4 NO. 3, 15, p. 302-306 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2005
7 Citations (Scopus)

Oxidative stress and antioxidant status in cancer patients and healthy subjects, a case-control study.

Adhikari, D., Baxi, J., Risal, S. & Singh, P. P., 1 Jan 2005, In : Nepal Medical College journal : NMCJ. 7, 2, p. 112-115 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2004
13 Citations (Scopus)

Typhoid fever in Dhulikhel hospital, Nepal.

Sharma, N., Koju, R., Karmacharya, B., Tamang, M. D., Makaju, R., Nepali, N., Shrestha, P. & Adhikari, D., 1 Jul 2004, In : Kathmandu University Medical Journal. 2, 3, p. 188-192 5 p.

Research output: Contribution to journalArticleResearchpeer-review