David Williams

Assoc Professor

20002018
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Research Output 2000 2018

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Article
2018

Neck pain: What if it is not musculoskeletal?

Vijiaratnam, N., Williams, D. R. R. & Bertram, K., May 2018, In : Australian Journal of General Practice. 47, 5, p. 279-282 3 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
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2017

Reversal of long term potentiation-like plasticity in primary motor cortex in patients with progressive supranuclear palsy

Bologna, M., Bertram, K., Paparella, G., Papi, C., Belvisi, D., Conte, A., Suppa, A., Williams, D. R. & Berardelli, A., 1 Sep 2017, In : Clinical Neurophysiology. 128, 9, p. 1547-1552 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Subjective perception of sleep benefit in Parkinson's disease: Valid or irrelevant?

Lee, W., Evans, A. & Williams, D. R., Sep 2017, In : Parkinsonism and Related Disorders. 42, p. 90-94 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2016

Clinical correlates of longitudinal brain atrophy in progressive supranuclear palsy

Tsai, R. M., Lobach, I. V., Bang, J., Whitwell, J. L., Senjem, M. L., Jack Jr, C. R., Rosen, H., Miller, B. L., Boxer, A. L. & AL-108-231 Investigators, 1 Jul 2016, In : Parkinsonism and Related Disorders. 28, p. 29-35 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Delays to the diagnosis of cervical dystonia

Bertram, K. L. & Williams, D. R., 2016, In : Journal of Clinical Neuroscience. 25, p. 62-64 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Frontal deficits differentiate progressive supranuclear palsy from Parkinson's disease

Lee, Y-E. C., Williams, D. & Anderson, J. F. I., 2016, In : Journal of Neuropsychology. 10, 1, p. 1 - 14 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Minimal clinically important worsening on the progressive supranuclear Palsy Rating Scale

Hewer, S., Varley, S., Boxer, A. L., Paul, E., Williams, D. R. & on behalf of the AL-108-231 Investigators, 1 Oct 2016, In : Movement Disorders. 31, 10, p. 1574-1577 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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MR parkinsonism index predicts vertical supranuclear gaze palsy in patients with PSP-parkinsonism

Quattrone, A., Morelli, M., Williams, D. R., Vescio, B., Arabia, G., Nigro, S., Nicoletti, G., Salsone, M., Novellino, F., Nisticò, R., Pucci, F., Chiriaco, C., Pugliese, P., Bosco, D. & Caracciolo, M., 20 Sep 2016, In : Neurology. 87, 12, p. 1266-1273 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Validation of a smartphone application measuring motor function in Parkinson's disease

Lee, W., Evans, A. & Williams, D. R., 2016, In : Journal of Parkinson's Disease. 6, 2, p. 371-382 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2015

Serotonergic markers in Parkinson's disease and levodopa-induced dyskinesias

Cheshire, P. A., Ayton, S., Bertram, K., Ling, H., Li, A., McLean, C. A., Halliday, G. M., O'Sullivan, S., Revesz, T., Finkelstein, D. I., Storey, E. & Williams, D., 2015, In : Movement Disorders. 30, 6, p. 796 - 804 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2014

Abnormal mitochondrial L-arginine transport contributes to the pathogenesis of heart failure and rexoygenation injury

Williams, D., Venardos, K., Byrne, M., Joshi, M., Horlock, D., Lam, N. T., Gregorevic, P., McGee, S. L. & Kaye, D. M., 2014, In : PLoS ONE. 9, 8, 11 p., e104643.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial

Boxer, A. L., Lang, A. E., Grossman, M., Knopman, D., Miller, B. L., Schneider, L. S., Doody, R. S., Lees, A. J., Golbe, L. I., Williams, D., Corvol, J-C., Ludolph, A., Burn, D. J., Lorenzl, S., Litvan, I., Roberson, E. D., Hoglinger, G. U., Koestler, M., Jack Jr, C. R., Van Deerlin, V. & 10 others, Randolph, C., Lobach, I. V., Heuer, H. W., Gozes, I., Parker, L., Whitaker, S., Hirman, J., Stewart, A. J., Gold, M. S. & Morimoto, B. H., 2014, In : The Lancet Neurology. 13, 7, p. 676 - 685 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Influence of single nucleotide polymorphisms in COMT , MAO-A and BDNF genes on dyskinesias and levodopa use in Parkinson's disease

Cheshire, P. A., Bertram, K., Ling, H., O'Sullivan, S. S., Halliday, G. M., McLean, C. A., Bras, J., Foltynie, T., Storey, E. & Williams, D., 2014, In : Neurodegenerative Diseases. 13, 1, p. 24 - 28 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Sex differences in Parkinson's disease

Lubomski, M., Rushworth, R. L., Lee, W., Bertram, K. & Williams, D., 2014, In : Journal of Clinical Neuroscience. 21, 9, p. 1503 - 1506 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

A cross-sectional study of clinical management, and provision of health services and their utilisation, by patients with Parkinson's disease in urban and regional Victoria

Lubomski, M., Rushworth, R. L., Lee, W., Bertram, K. & Williams, D., 2013, In : Journal of Clinical Neuroscience. 20, 1, p. 102 - 106 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterising the uncommon corticobasal syndrome presentation of sporadic Creutzfeldt-Jakob disease

Lee, W., Simpson, M. A., Ling, H., McLean, C. A., Collins, S. J. & Williams, D., 2013, In : Parkinsonism and Related Disorders. 19, 1, p. 81 - 85 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Clinical, laboratory and electrophysiological features of Morvan's Fibrillary Chorea

Lee, W., Day, T. & Williams, D., 2013, In : Journal of Clinical Neuroscience. 20, 9, p. 1246 - 1249 4 p.

Research output: Contribution to journalArticleResearchpeer-review

MM2 subtype of sporadic Creutzfeldt-Jakob disease may underlie the clinical presentation of progressive supranuclear palsy

Petrovic, I. N., Martin-Bastida, A., Massey, L. A., Ling, H., O'Sullivan, S. S., Williams, D., Holton, J. L., Revesz, T., Ironside, J. W., Lees, A. J. & Silveira-Moriyama, L., 2013, In : Journal of Neurology. 260, 4, p. 1031 - 1036 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Parkinsonian syndromes

Williams, D. & Litvan, I., 2013, In : CONTINUUM Lifelong Learning in Neurology. 19, 5, p. 1189 - 1212 24 p.

Research output: Contribution to journalArticleResearchpeer-review

Safety and efficacy of botulinum toxin in primary orthostatic tremor

Bertram, K., Sirisena, D., Cowey, M., Hill, A. & Williams, D., 2013, In : Journal of Clinical Neuroscience. 20, 11, p. 1503 - 1505 3 p.

Research output: Contribution to journalArticleResearchpeer-review

The midbrain to pons ratio: a simple and specific MRI sign of progressive supranuclear palsy

Massey, L. A., Jager, H. R., Paviour, D. C., O'Sullivan, S. S., Ling, H., Williams, D., Kallis, C., Holton, J. L., Revesz, T., Burn, D. J., Yousry, T., Lees, A. J., Fox, N. C. & Micallef, C., 2013, In : Neurology. 80, 20, p. 1856 - 1861 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2012

Abnormal cortical synaptic plasticity in primary motor area in progressive supranuclear palsy

Conte, A., Belvisi, D., Bologna, M., Ottaviani, D., Fabbrini, G., Colosimo, C., Williams, D. & Berardelli, A., 2012, In : Cerebral Cortex. 22, 3, p. 693 - 700 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Clinical features and criteria for the diagnosis of progressive supranuclear palsy

Williams, D. & Lee, W., 2012, In : Neurodegenerative Disease Management. 2, p. 125 - 133 9 p.

Research output: Contribution to journalArticleOther

Cognitive testing in the diagnosis of parkinsonian disorders: a critical appraisal of the literature

Lee, W., Williams, D. & Storey, E., 2012, In : Movement Disorders. 27, 10, p. 1243 - 1254 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Comparison of gait in progressive supranuclear palsy, Parkinson's disease and healthy older adults

Egerton, T., Williams, D. & Iansek, R., 2012, In : BMC Neurology. 12, Art. No.: 116, p. 1 - 6 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Conventional magnetic resonance imaging in confirmed progressive supranuclear palsy and multiple system atrophy

Massey, L. A., Micallef, C., Paviour, D. C., O'Sullivan, S. S., Ling, H., Williams, D., Kallis, C., Holton, J. L., Revesz, T., Burn, D. J., Yousry, T., Lees, A. J., Fox, N. C. & Jager, H. R., 2012, In : Movement Disorders. 27, 14, p. 1755 - 1762 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Critical appraisal of the role of davunetide in the treatment of progressive supranuclear palsy

Gold, M., Lorenzl, S., Stewart, A. J., Morimoto, B. H., Williams, D. & Gozes, I., 2012, In : Neuropsychiatric Disease and Treatment. 8, p. 85 - 93 9 p.

Research output: Contribution to journalArticleOther

Development and assessment of sensitive immuno-PCR assays for the quantification of cerebrospinal fluid three- and four-repeat tau isoforms in tauopathies

Luk, C., Compta, Y., Magdalinou, N., Marti, M. J., Hondhamuni, G., Zetterberg, H., Blennow, K., Constantinescu, R., Pijnenburg, Y., Mollenhauer, B., Trenkwalder, C., van Swieten, J. C., Chiu, W. Z., Borroni, B., Camara, A., Cheshire, P. A., Williams, D., Lees, A. J. & de Silva, R., 2012, In : Journal of Neurochemistry. 123, 3, p. 396 - 405 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Diagnosis of dystonic syndromes--a new eight-question approach

Bertram, K. & Williams, D., 2012, In : Nature Reviews Neurology. 8, 5, p. 275 - 283 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Serotonergic involvement in levodopa-induced dyskinesias in Parkinson's disease

Cheshire, P. A. & Williams, D., 2012, In : Journal of Clinical Neuroscience. 19, 3, p. 343 - 348 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Visual hallucinations in the differential diagnosis of parkinsonism

Bertram, K. & Williams, D., 2012, In : Journal of Neurology, Neurosurgery and Psychiatry. 83, 4, p. 448 - 452 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2011

Alpha-synuclein in Parkinson disease and other neurodegenerative disorders

Eller, M. & Williams, D., 2011, In : Clinical Chemistry and Laboratory Medicine. 49, 3, p. 403 - 408 6 p.

Research output: Contribution to journalArticleOther

Does levodopa accelerate the pathologic process in Parkinson disease brain?

Parkkinen, L., O'Sullivan, S., Kuoppamaki, M., Collins, C., Kallis, C., Holton, J., Williams, D., Revesz, T. & Lees, A., 2011, In : Neurology. 77, 15, p. 1420 - 1426 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Inhibitory control during smooth pursuit in Parkinson's disease and Huntington's disease

Henderson, T., Georgiou-Karistianis, N., White, O., Millist, L., Williams, D., Churchyard, A. & Fielding, J., 2011, In : Movement Disorders. 26, 10, p. 1893 - 1899 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Lewy- and Alzheimer-type pathologies in Parkinson's disease dementia: which is more important?

Compta, Y., Parkkinen, L., O'Sullivan, S., Vandrovcova, J., Holton, J., Collins, C., Lashley, T., Kallis, C., Williams, D., de Silva, R., Lees, A. & Revesz, T., 2011, In : Brain. 134, 5, p. 1493 - 1505 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Mutations in the N-terminal actin-binding domain of filamin C cause a distal myopathy

Duff, R., Tay, V., Hackman, P., Ravenscroft, G., McLean, C. A., Kennedy, P., Steinbach, A., Schoffler, W., van der Ven, P., Furst, D., Song, J., Djinovic-Carugo, K., Penttila, S., Raheem, O., Reardon, K., Malandrini, A., Gambelli, S., Villanova, M., Nowak, K., Williams, D. & 4 others, Landers, J., Brown, Jr., R., Udd, B. & Laing, N., 2011, In : American Journal of Human Genetics. 88, 6, p. 729 - 740 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Postural instability, frontotemporal dementia, and ophthalmoplegia: clinicopathological case

Cardoso, F., Hodges, J., Evans, A., Revesz, T. & Williams, D., 2011, In : Movement Disorders. 26, 10, p. 1808 - 1813 6 p.

Research output: Contribution to journalArticleOther

Progressive parkinsonism, oculomotor abnormalities and autonomic dysfunction: clinicopathological case

Fabbrini, G., Merello, M., Evans, A., Lees, A., Holton, J. & Williams, D., 2011, In : Movement Disorders. 26, 3, p. 424 - 429 6 p.

Research output: Contribution to journalArticleOther

Putaminal upregulation of FosB/ΔFosB-like immunoreactivity in Parkinson's disease patients with Dyskinesia

Lindgren, H. S., Rylander, D., Iderberg, H., Andersson, M., O'Sullivan, S., Williams, D. R., Lees, A. J. & Cenci, M. A., 1 Dec 2011, In : Journal of Parkinson's Disease. 1, 4, p. 347-357 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Testing an aetiological model of visual hallucinations in Parkinson's disease

Gallagher, D., Parkkinen, L., O'Sullivan, S., Spratt, A., Shah, A., Davey, C., Bremner, F., Revesz, T., Williams, D., Lees, A. & Schrag, A., 2011, In : Brain. 134, p. 3299 - 3309 11 p.

Research output: Contribution to journalArticleResearchpeer-review

The effect of drug treatment on neurogenesis in Parkinson's disease

O'Sullivan, S., Johnson, M., Williams, D., Revesz, T., Holton, J., Lees, A. & Perry, E., 2011, In : Movement Disorders. 26, 1, p. 45 - 50 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2010

Does corticobasal degeneration exist? A clinicopathological re-evaluation

Ling, H., O'Sullivan, S., Holton, J., Revesz, T., Massey, L., Williams, D., Paviour, D. & Lees, A., 2010, In : Brain. 133, Pt 7, p. 2045 - 2057 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Hyposmia in progressive supranuclear palsy

Silveira-Moriyama, L., Hughes, G., Church, A., Ayling, H., Williams, D., Petrie, A., Holton, J., Revesz, T., Kingsbury, A., Morris, H., Burn, D. & Lees, A., 2010, In : Movement Disorders. 25, 5, p. 570 - 577 8 p.

Research output: Contribution to journalArticleResearchpeer-review

What features improve the accuracy of the clinical diagnosis of progressive supranuclear palsy-parkinsonism (PSP-P)?

Williams, D. & Lees, A., 2010, In : Movement Disorders. 25, 3, p. 357 - 362 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2009

A clinico-pathological study of subtypes in Parkinson's disease

Selikhova, M., Williams, D. R., Kempster, P. A., Holton, J. L., Revesz, T. & Lees, A. J., 2009, In : Brain. 132, 11, p. 2947 - 2957 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Biological fluid biomarkers in neurodegenerative parkinsonism

Eller, M. & Williams, D. R., 2009, In : Nature Reviews Neuroscience. 5, 10, p. 561 - 570 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Concomitant progressive supranuclear palsy and multiple system atrophy: More than a simple twist of fate?

Silveira-Moriyama, L., Gonzalez, A. M., O'Sullivan, S. S., Williams, D. R., Massey, L. A., Parkkinen, L., Ahmed, Z., de Silva, R., Chacon, J. R., Revesz, T., Lees, A. J. & Holton, J. L., 2009, In : Neuroscience Letters. 467, 3, p. 208 - 211 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Degeneration in different parkinsonian syndromes relates to astrocyte type and astrocyte protein expression

Song, Y. J. C., Halliday, G., Holton, J. L., Lashley, T., O'Sullivan, S. S., McCann, H., Lees, A. J., Ozawa, T., Williams, D. R., Lockhart, P. J. & Revesz, T., 2009, In : Journal of Neuropathology and Experimental Neurology. 68, 10, p. 1073 - 1083 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Development of a sensitive ELISA for quantification of three- and four-repeat tau isoforms in tauopathies

Luk, C., Giovannoni, G., Williams, D. R., Lees, A. J. & de Silva, R., 2009, In : Journal of Neuroscience Methods. 180, 1, p. 34 - 42 9 p.

Research output: Contribution to journalArticleResearchpeer-review