David Walker

Assoc Professor

1986 …2019
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Research Output 1986 2019

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2019

Evaluation of 3K3A-Activated Protein C to Treat Neonatal Hypoxic Ischemic Brain Injury in the Spiny Mouse

Ellery, S. J., Goss, M. G., Brew, N., Dickinson, H., Hale, N., LaRosa, D. A., Walker, D. W. & Wong, F. Y., 15 Jan 2019, In : Neurotherapeutics. 16, 1, p. 231-243 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Unicorn babies: Understanding circulating and cerebral creatine levels of the preterm infant. An observational study protocol

Berry, M. J., Schlegel, M., Kowalski, G. M., Bruce, C. R., Callahan, D. L., Davies-Tuck, M. L., Dickinson, H., Goodson, A., Slocombe, A., Snow, R. J., Walker, D. W. & Ellery, S. J., 1 Jan 2019, In : Frontiers in Physiology. 10, MAR, 8 p., 142.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
2018

Dobutamine treatment reduces inflammation in the preterm fetal sheep brain exposed to acute hypoxia

Brew, N., Nakamura, S., Hale, N., Azhan, A., Davies, G. I., Nitsos, I., Miller, S. L., Walker, D. W. & Wong, F. Y., 1 Sep 2018, In : Pediatric Research. 84, 3, p. 442-450 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Effects of hypoxia-ischemia and inotropes on expression of cardiac adrenoceptors in the preterm fetal sheep

Hutchinson, D. S., Brew, N., Vu, T., Merlin, J., Hale, N., Walker, D. W. & Wong, F. Y., 1 Nov 2018, In : Journal of Applied Physiology. 125, 5, p. 1368-1377 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2017

Altered placental tryptophan metabolic pathway in human fetal growth restriction

Murthi, P., Wallace, E. M. & Walker, D. W., 1 Apr 2017, In : Placenta. 52, p. 62-70 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Cerebellar Changes in Guinea Pig Offspring Following Suppression of Neurosteroid Synthesis During Late Gestation

Cumberland, A. L., Palliser, H. K., Walker, D. W. & Hirst, J. J., 1 Apr 2017, In : Cerebellum. 16, 2, p. 306-313 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Cerebral haemodynamic response to somatosensory stimulation in near-term fetal sheep

Nakamura, S., Walker, D. W. & Wong, F. Y., 15 Feb 2017, In : Journal of Physiology. 595, 4, p. 1289-1303 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Cerebral haemodynamic response to somatosensory stimulation in neonatal lambs

Nakamura, S., Walker, D. W. & Wong, F. Y., 1 Sep 2017, In : The Journal of Physiology. 595, 17, p. 6007-6021 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Creatine biosynthesis and transport by the term human placenta

Ellery, S. J., Della Gatta, P. A., Bruce, C. R., Kowalski, G. M., Davies-Tuck, M., Mockler, J. C., Murthi, P., Walker, D. W., Snow, R. J. & Dickinson, H., 1 Apr 2017, In : Placenta. 52, p. 86-93 8 p.

Research output: Contribution to journalArticleResearchpeer-review

De novo transcriptome assembly for the spiny mouse (Acomys cahirinus)

Mamrot, J., Legaie, R., Ellery, S. J., Wilson, T., Seemann, T., Powell, D. R., Gardner, D. K., Walker, D. W., Temple-Smith, P., Papenfuss, A. T. & Dickinson, H., 1 Dec 2017, In : Scientific Reports. 7, 1, 15 p., 8996.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Description of a method for inducing fetal growth restriction in the spiny mouse

Dickinson, H., Ellery, S., Davies-Tuck, M., Tolcos, M., Nitsos, I., Walker, D. W. & Miller, S. L., Oct 2017, In : Journal of Developmental Origins of Health and Disease. 8, 5, p. 550-555 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Does maternal-fetal transfer of creatine occur in pregnant sheep?

Baharom, S., De Matteo, R., Ellery, S., Della Gatta, P., Bruce, C. R., Kowalski, G. M., Hale, N., Dickinson, H., Harding, R., Walker, D. & Snow, R. J., 2017, In : American Journal of Physiology - Endocrinology and Metabolism. 313, 1, p. E75-E83

Research output: Contribution to journalArticleResearchpeer-review

Effects of combined IUGR and prenatal stress on the development of the hippocampus in a fetal Guinea pig model

Cumberland, A. L., Palliser, H. K., Rani, P., Walker, D. W. & Hirst, J. J., 1 Oct 2017, In : Journal of Developmental Origins of Health and Disease. 8, 5, p. 584-596 13 p.

Research output: Contribution to journalArticleResearchpeer-review

First evidence of a menstruating rodent: the spiny mouse (Acomys cahirinus)

Bellofiore, N., Ellery, S. J., Mamrot, J., Walker, D. W., Temple-Smith, P. & Dickinson, H., 1 Jan 2017, In : American Journal of Obstetrics and Gynecology. 216, 1, p. 40.e1-40.e11

Research output: Contribution to journalArticleResearchpeer-review

Increased anxiety-like phenotype in female guinea pigs following reduced neurosteroid exposure in utero

Cumberland, A. L., Palliser, H. K., Crombie, G. K., Walker, D. W. & Hirst, J. J., 1 May 2017, In : International Journal of Developmental Neuroscience. 58, p. 50-58 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Renal dysfunction in early adulthood following birth asphyxia in male spiny mice, and its amelioration by maternal creatine supplementation during pregnancy

Ellery, S. J., Larosa, D. A., Cullen-Mcewen, L. A., Brown, R. D., Snow, R. J., Walker, D. W., Kett, M. M. & Dickinson, H., 1 Apr 2017, In : Pediatric Research. 81, 4, p. 646-653 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2016

Dietary creatine supplementation during pregnancy: a study on the effects of creatine supplementation on creatine homeostasis and renal excretory function in spiny mice

Ellery, S. J., LaRosa, D. A., Kett, M. M., Della Gatta, P. A., Snow, R. J., Walker, D. W. & Dickinson, H., 1 Aug 2016, In : Amino Acids. 48, 8, p. 1819-1830 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Dopamine treatment during acute hypoxia is neuroprotective in the developing sheep brain

Brew, N., Azhan, A., den Heijer, I., Boomgardt, M., Davies, G. I., Nitsos, I., Miller, S. L., Walker, A. M., Walker, D. W. & Wong, F. Y., 1 Mar 2016, In : Neuroscience. 316, p. 82-93 12 p.

Research output: Contribution to journalArticleResearchpeer-review

How Systemic Inquiry Releases Citizen Knowledge to Reform Schools: Community Scorecard Case Studies

Walker, D. W., 1 Aug 2016, In : Systemic Practice and Action Research. 29, 4, p. 313-334 22 p.

Research output: Contribution to journalArticleResearchpeer-review

Maternal creatine in pregnancy: a retrospective cohort study

Dickinson, H., Davies-Tuck, M., Ellery, S. J., Grieger, J. A., Wallace, E. M., Snow, R. J., Walker, D. W. & Clifton, V. L., 1 Oct 2016, In : BJOG: an International Journal of Obstetrics and Gynaecology. 123, 11, p. 1830-1838 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Maternal creatine supplementation during pregnancy prevents acute and long-term deficits in skeletal muscle after birth asphyxia: A study of structure and function of hind limb muscle in the spiny mouse

Larosa, D. A., Ellery, S. J., Snow, R. J., Walker, D. W. & DIckinson, H., 1 Dec 2016, In : Pediatric Research. 80, 6, p. 852-860 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Maternal creatine supplementation during pregnancy prevents long-term changes in diaphragm muscle structure and function after birth asphyxia

LaRosa, D. A., Ellery, S. J., Parkington, H. C., Snow, R. J., Walker, D. W. & Dickinson, H., 1 Mar 2016, In : PLoS ONE. 11, 3, 17 p., e0149840.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Ontogenetic Change in the Regional Distribution of Dehydroepiandrosterone-Synthesizing Enzyme and the Glucocorticoid Receptor in the Brain of the Spiny Mouse (Acomys cahirinus)

Quinn, T. A., Ratnayake, U., Dickinson, H., Castillo-Melendez, M. & Walker, D. W., 1 Feb 2016, In : Developmental Neuroscience. 38, 1, p. 54-73 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Role of the Placental Vitamin D Receptor in Modulating Feto-Placental Growth in Fetal Growth Restriction and Preeclampsia-Affected Pregnancies

Murthi, P., Yong, H. E. J., Nguyen, T. P. H., Ellery, S., Singh, H., Abdul Rahman, R., Dickinson, H., Walker, D. W., Davies-Tuck, M., Wallace, E. M. & Ebeling, P. R., 18 Feb 2016, In : Frontiers in Physiology. 7, p. 1-7 7 p., 43.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Severity and timing: How prenatal stress exposure affects glial developmental, emotional behavioural and plasma neurosteroid responses in guinea pig offspring

Bennett, G. A., Palliser, H. K., Walker, D. & Hirst, J., 1 Aug 2016, In : Psychoneuroendocrinology. 70, p. 47-57 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2015

Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans

Yan, E. B., Frugier, T. J., Lim, C. K., Heng, B., Sundaram, G., Tan, M., Rosenfeld, J. V., Walker, D. W., Guillemin, G. J. & Morganti-Kossmann, M. C., 12 Dec 2015, In : Journal of Neuroinflammation. 12, 1, 17 p., 110.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Confirmed dioestrus in pseudopregnant mice using vaginal exfoliative cytology improves embryo transfer implantation rate

Mamrot, J., Pangestu, M., Walker, D. W., Gardner, D. K. & Dickinson, H., 2015, In : Reproductive BioMedicine Online. 31, 4 (Art. ID : 1396), p. 538 - 543 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of postnatal progesterone therapy following preterm birth on neurosteroid concentrations and cerebellar myelination in guinea pigs

Palliser, H. K., Kelleher, M. A., Tolcos, M., Walker, D. W. & Hirst, J., 2015, In : Journal of Developmental Origins of Health and Disease. 6, 4, p. 350 - 361 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Maternal creatine homeostasis is altered during gestation in the spiny mouse: Is this a metabolic adaptation to pregnancy?

Ellery, S. J., LaRosa, D. A., Kett, M. M., Della Gatta, P., Snow, R., Walker, D. W. & Dickinson, H., 14 Apr 2015, In : BMC Pregnancy and Childbirth. 15, 1, 9 p., 92.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Prenatal stress alters hippocampal neuroglia and increases anxiety in childhood

Bennett, G. A., Palliser, H. K., Shaw, J. C., Walker, D. W. & Hirst, J., 2015, In : Developmental Neuroscience. 37, 6, p. 533 - 545 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Preterm birth affects GABAA receptor subunit mRNA levels during the foetal-to-neonatal transition in guinea pigs

Shaw, J. C., Palliser, H. K., Walker, D. W. & Hirst, J., 2015, In : Journal of Developmental Origins of Health and Disease. 6, 3, p. 250 - 260 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Transcutaneous measurement of glomerular filtration rate in small rodents: through the skin for the win?

Ellery, S. J., Cai, X., Walker, D. W., Dickinson, H. & Kett, M. M., 2015, In : Nephrology. 20, 3, p. 117 - 123 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2014

Adrenal steroidogenesis following prenatal dexamethasone exposure in the spiny mouse

Quinn, T. A., Ratnayake, U., Castillo-Melendez, M. E., Moritz, K. M., Dickinson, H. & Walker, D. W., 2014, In : Journal of Endocrinology. 221, 2, p. 347 - 362 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Antenatal antioxidant treatment with melatonin to decrease newborn neurodevelopmental deficits and brain injury caused by fetal growth restriction

Miller, S. L., Yawno, T., Alers, N. O., Zakhem, M. E., Supramaniam, V. G., van Zyl, N., Sabaretnam, T., Loose, J. M., Drummond, G. R., Walker, D. W., Jenkin, G. & Wallace, E. M., 2014, In : Journal of Pineal Research. 56, 3, p. 283 - 294 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Cerebral vascular regulation and brain injury in preterm infants

Brew, N., Walker, D. W. & Wong, F. Y-W., 2014, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 306, 11, p. R773 - R786 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Creatine supplementation during pregnancy: summary of experimental studies suggesting a treatment to improve fetal and neonatal morbidity and reduce mortality in high-risk human pregnancy

Dickinson, H., Ellery, S. J., Ireland, Z. J., LaRosa, D. A., Snow, R. & Walker, D. W., 2014, In : BMC Pregnancy and Childbirth. 14, 1 (Art. ID: 150), p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Maternal alcohol consumption in pregnancy enhances arterial stiffness and alters vasodilator function that varies between vascular beds in fetal sheep

Parkington, H. C., Kenna, K. R., Sozo, F., Coleman, H. A., Bocking, A., Brien, J. F., Harding, R. L., Walker, D. W., Morley, R. & Tare, M., 2014, In : The Journal of Physiology. 592, 12, p. 2591 - 2603 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Neuroactive steroids in pregnancy: key regulatory and protective roles in the foetal brain

Hirst, J. J., Kelleher, M. A., Walker, D. W. & Palliser, H. K., 2014, In : Journal of Steroid Biochemistry and Molecular Biology. 139, p. 144 - 153 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Prenatal exposure to the viral mimetic poly I:C alters fetal brain cytokine expression and postnatal behaviour

Ratnayake, U., Quinn, T. A., LaRosa, D. A., Dickinson, H. & Walker, D. W., 2014, In : Developmental Neuroscience. 36, 2, p. 83 - 94 12 p.

Research output: Contribution to journalArticleResearchpeer-review

The effects of betamethasone on allopregnanolone concentrations and brain development in preterm fetal sheep

Yawno, T., Mortale, M., Sutherland, A. E., Jenkin, G., Wallace, E. M., Walker, D. W. & Miller, S. L., 2014, In : Neuropharmacology. 85, p. 342 - 348 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Understanding the behavioural phenotype of the precocial spiny mouse

Ratnayake, U., Quinn, T. A., Daruwalla, K., Dickinson, H. & Walker, D. W., 2014, In : Behavioural Brain Research. 275, p. 62 - 71 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

Creatine for women in pregnancy for neuroprotection of the fetus (Protocol)

Bain, E., Wilkinson, D., Middleton, P. F., Crowther, C., Dickinson, H. & Walker, D. W., 2013, In : Cochrane Database of Systematic Reviews. 11, 10 p., CD010846.

Research output: Contribution to journalArticleResearchpeer-review

Creatine pretreatment prevents birth asphyxiainduced injury of the newborn spiny mouse kidney

Ellery, S. J., Ireland, Z. J., Kett, M. M., Snow, R., Walker, D. W. & Dickinson, H., 2013, In : Pediatric Research. 73, 2, p. 201 - 208 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Cytokines and the neurodevelopmental basis of mental illness

Ratnayake, U., Quinn, T. A., Walker, D. W. & Dickinson, H., 2013, In : Frontiers in Neuroscience. 7, p. 1 - 9 9 p., 180.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Effects of prenatal stress on fetal neurodevelopment and responses to maternal neurosteroid treatment in Guinea pigs

Bennett, G. A., Palliser, H. K., Saxby, B., Walker, D. W. & Hirst, J., 2013, In : Developmental Neuroscience. 35, 5, p. 416 - 426 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Experimental modelling of the consequences of brief late gestation asphyxia on newborn lamb behaviour and brain structure

Zakhem, M. E., Baburamani, A. A., Cabalag, C., Yawno, T., Witjaksono, A., Miller, S. L. & Walker, D. W., 2013, In : PLoS ONE. 8, 11, 13 p., e77377.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Maternal dietary creatine supplementation does not alter the capacity for creatine synthesis in the newborn spiny mouse

Dickinson, H., Ireland, Z. J., LaRosa, D. A., O'Connell, B. A., Ellery, S. J., Snow, R. & Walker, D. W., 2013, In : Reproductive Sciences. 20, 9, p. 1096 - 1102 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Meconium fatty acid ethyl esters as biomarkers of late gestational ethanol exposure and indicator of ethanol-induced multi-organ injury in fetal sheep

Zelner, I., Kenna, K. R., Brien, J. F., Bocking, A. D., Harding, R., Walker, D. W. & Koren, G., 2013, In : PLoS ONE. 8, 3, 10 p., e59168.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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