Projects per year
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2017 2021
Molecular determinants of drug binding and selectivity at muscarinic acetylcholine receptors
Thal, D., Gooley, P. R. & Dror, R.
National Health & Medical Research Council (NHMRC)
1/01/18 → 31/12/21
Project: Research
Molecular insight into allosteric modulation of G protein-coupled receptors
Australian Research Council (ARC)
1/01/17 → 31/12/19
Project: Research
Engineering new tools to aid structure determination of membrane proteins
Thal, D., Veldhuis, N., Wang, H. & Scott, D. J.
Project: Research
Research Output 2006 2018
- 16 Article
Phase-plate cryo-EM structure of a biased agonistbound human GLP-1 receptor-Gs complex
Liang, Y. L., Khoshouei, M., Glukhova, A., Furness, S. G. B., Zhao, P., Clydesdale, L., Koole, C., Truong, T. T., Thal, D. M., Lei, S., Radjainia, M., Danev, R., Baumeister, W., Wang, M. W., Miller, L. J., Christopoulos, A., Sexton, P. M. & Wootten, D., 1 Mar 2018, In : Nature. 555, 7694, p. 121-125 5 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Structure of the adenosine-bound human adenosine A1 receptor-Gi complex
Draper-Joyce, C. J., Khoshouei, M., Thal, D. M., Liang, Y. L., Nguyen, A. T. N., Furness, S. G. B., Venugopal, H., Baltos, J. A., Plitzko, J. M., Danev, R., Baumeister, W., May, L. T., Wootten, D., Sexton, P. M., Glukhova, A. & Christopoulos, A., 20 Jun 2018, In : Nature. 558, 7711, p. 559-565 7 p.Research output: Contribution to journal › Article › Research › peer-review
The action of a negative allosteric modulator at the dopamine D2 receptor is dependent upon sodium ions
Draper-Joyce, C. J., Verma, R. K., Michino, M., Shonberg, J., Kopinathan, A., Klein Herenbrink, C., Scammells, P. J., Capuano, B., Abramyan, A. M., Thal, D. M., Javitch, J. A., Christopoulos, A., Shi, L. & Lane, J. R., 1 Dec 2018, In : Scientific Reports. 8, 1, 12 p., 1208.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
The structural determinants of the bitopic binding mode of a negative allosteric modulator of the dopamine D2 receptor
Draper-Joyce, C. J., Michino, M., Verma, R. K., Klein Herenbrink, C., Shonberg, J., Kopinathan, A., Scammells, P. J., Capuano, B., Thal, D. M., Javitch, J. A., Christopoulos, A., Shi, L. & Lane, J. R., 1 Feb 2018, In : Biochemical Pharmacology. 148, p. 315-328 14 p.Research output: Contribution to journal › Article › Research › peer-review
Phase-plate cryo-EM structure of a class B GPCR-G-protein complex
Liang, Y-L., Khoshouei, M., Radjainia, M., Zhang, Y., Glukhova, A., Tarrasch, J., Thal, D., Furness, S. G. B., Christopoulos, G., Coudrat, T., Danev, R., Baumeister, W., Miller, L. J., Christopoulos, A., Kobilka, B., Wootten, D., Skiniotis, G. & Sexton, P., 1 Jun 2017, In : Nature. 546, 7656, p. 118-123 6 p.Research output: Contribution to journal › Article › Research › peer-review