Projects per year
Network
Recent external collaboration on country level. Dive into details by clicking on the dots or
Projects
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Using protein structure and dynamics to facilitate drug discovery
1/01/21 → 31/12/25
Project: Research
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Engineering new tools to aid structure determination of membrane proteins
Thal, D., Veldhuis, N., Wang, H. & Scott, D. J.
9/10/19 → 8/10/22
Project: Research
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Molecular determinants of drug binding and selectivity at muscarinic acetylcholine receptors
Thal, D., Gooley, P. R. & Dror, R.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/18 → 31/12/21
Project: Research
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Molecular insight into allosteric modulation of G protein-coupled receptors
Australian Research Council (ARC)
1/01/17 → 31/12/19
Project: Research
Research output
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Crystal structure of the M5 muscarinic acetylcholine receptor
Vuckovic, Z., Gentry, P. R., Berizzi, A. E., Hirata, K., Varghese, S., Thompson, G., van der Westhuizen, E. T., Burger, W. A. C., Rahmani, R., Valant, C., Langmead, C. J., Lindsley, C. W., Baell, J. B., Tobin, A. B., Sexton, P. M., Christopoulos, A. & Thal, D. M., 17 Dec 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 51, p. 26001-26007 7 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile4 Citations (Scopus) -
Phase-plate cryo-EM structure of a biased agonistbound human GLP-1 receptor-Gs complex
Liang, Y. L., Khoshouei, M., Glukhova, A., Furness, S. G. B., Zhao, P., Clydesdale, L., Koole, C., Truong, T. T., Thal, D. M., Lei, S., Radjainia, M., Danev, R., Baumeister, W., Wang, M. W., Miller, L. J., Christopoulos, A., Sexton, P. M. & Wootten, D., 1 Mar 2018, In : Nature. 555, 7694, p. 121-125 5 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile138 Citations (Scopus) -
Recent advances in the determination of G protein-coupled receptor structures
Thal, D. M., Vuckovic, Z., Draper-Joyce, C. J., Liang, Y-L., Glukhova, A., Christopoulos, A. & Sexton, P. M., 1 Aug 2018, In : Current Opinion in Structural Biology. 51, p. 28-34 7 p.Research output: Contribution to journal › Article › Research › peer-review
26 Citations (Scopus) -
Structural insights into G-protein-coupled receptor allostery
Thal, D. M., Glukhova, A., Sexton, P. M. & Christopoulos, A., 5 Jul 2018, In : Nature. 559, 7712, p. 45-53 9 p.Research output: Contribution to journal › Review Article › Research › peer-review
98 Citations (Scopus) -
Structure of the adenosine-bound human adenosine A1 receptor-Gi complex
Draper-Joyce, C. J., Khoshouei, M., Thal, D. M., Liang, Y. L., Nguyen, A. T. N., Furness, S. G. B., Venugopal, H., Baltos, J. A., Plitzko, J. M., Danev, R., Baumeister, W., May, L. T., Wootten, D., Sexton, P. M., Glukhova, A. & Christopoulos, A., 20 Jun 2018, In : Nature. 558, 7711, p. 559-565 7 p.Research output: Contribution to journal › Article › Research › peer-review
120 Citations (Scopus)