1985 …2024

Research output per year

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Research Output

2013

Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity

Hawkins, E. D., Oliaro, J., Kallies, A., Belz, G. T., Filby, A., Hogan, T., Haynes, N. M., Ramsbottom, K. M., Van Ham, V., Kinwell, T., Seddon, B., Davies, D., Tarlinton, D., Lew, A. M., Humbert, P. O. & Russell, S. M., 2013, In : Nature Communications. 4, 1801.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
50 Citations (Scopus)
2012

Activated mouse B cells lack expression of granzyme B

Hagn, M., Belz, G. T., Kallies, A., Sutton, V. R., Thia, K. Y. T., Tarlinton, D. M., Hawkins, E. D. & Trapani, J. A., 15 Apr 2012, In : Journal of Immunology. 188, 8, p. 3886-3892 7 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Attenuation of phosphoinositide 3-kinase delta signaling restrains autoimmune disease

Maxwell, M. J., Tsantikos, E., Kong, A. M., Vanhaesebroeck, B., Tarlinton, D. M. & Hibbs, M., 2012, In : Journal of Autoimmunity. 38, 4, p. 381 - 391 11 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1

Karnowski, A., Chevrier, S., Belz, G. T., Mount, A. M., Emslie, D., D'Costa, K., Tarlinton, D. M., Kallies, A. & Corcoran, L. M., Oct 2012, In : Journal of Experimental Medicine. 209, 11, p. 2049-2064 16 p.

Research output: Contribution to journalArticleResearchpeer-review

114 Citations (Scopus)

B-cell differentiation: Instructive one day, stochastic the next

Tarlinton, D., 10 Apr 2012, In : Current Biology. 22, 7, p. R235-R237 3 p.

Research output: Contribution to journalArticleOtherpeer-review

3 Citations (Scopus)

B-cell lymphomas: Getting in the zone!

Tarlinton, D., 13 Sep 2012, In : Blood. 120, 11, p. 2158-2159 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

1 Citation (Scopus)

Determining germinal centre B cell fate

Zotos, D. & Tarlinton, D. M., Jun 2012, In : Trends in Immunology. 33, 6, p. 281-288 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

60 Citations (Scopus)

Genetic interdependence of lyn and negative regulators of B cell receptor signalling in autoimmune disease development

Tsantikos, E., Maxwell, M. J., Kountouri, N., Harder, K. W., Tarlinton, D. M. & Hibbs, M., 2012, In : Journal of Immunology. 189, 4, p. 1726 - 1736 11 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

High rate of antibody secretion is not integral to plasma cell differentiation as revealed by XBP-1 deficiency

Taubenheim, N., Tarlinton, D. M., Crawford, S., Corcoran, L. M., Hodgkin, P. D. & Nutt, S. L., 1 Oct 2012, In : Journal of Immunology. 189, 7, p. 3328-3338 11 p.

Research output: Contribution to journalArticleResearchpeer-review

60 Citations (Scopus)

Loss of STAT6 promotes autoimmune disease and atopy on a susceptible genetic background

Lau, M., Tsantikos, E., Maxwell, M. J., Tarlinton, D. M., Anderson, G. & Hibbs, M., 2012, In : Journal of Autoimmunity. 39, 4, p. 388 - 397 10 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Lyn-dependent signaling regulates the innate immune response by controlling dendritic cell activation of NK cells

Krebs, D. L., Chehal, M. K., Sio, A., Huntington, N. D., Da, M. L., Ziltener, P., Inglese, M., Kountouri, N., Priatel, J. J., Jones, J., Tarlinton, D. M., Anderson, G. P., Hibbs, M. & Harder, K. W., 2012, In : Journal of Immunology. 188, 10, p. 5094 - 5105 12 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Multiple routes to B-cell memory

Good-Jacobson, K. L. & Tarlinton, D. M., 2012, In : International Immunology. 24, 7, p. 403 - 408 6 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)

Phosphatidylinositol-3 kinase activity in B cells is negatively regulated by Lyn tyrosine kinase

Xu, Y., Huntington, N. D., Harder, K. W., Nandurkar, H., Hibbs, M. & Tarlinton, D. M., 2012, In : Immunology and Cell Biology. 90, 9, p. 903 - 911 9 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

The development and fate of follicular helper T cells defined by an IL-21 reporter mouse

Luthje, K., Kallies, A., Shimohakamada, Y., Belz, G. T., Light, A., Tarlinton, D. & Nutt, S. L., 2012, In : Nature Immunology. 13, 5, p. 491 - 498 8 p.

Research output: Contribution to journalArticleResearchpeer-review

208 Citations (Scopus)

The tetraspanin CD37 orchestrates the alpha(4)beta(1) integrin-Akt signaling axis and supports long-lived plasma cell survival

van Spriel, A. B., de Keijzer, S., van der Schaaf, A., Gartlan, K., Sofi, M., Light, A., Linssen, P. C., Boezeman, J. B., Zuidscherwoude, M., Reinieren-Beeren, I., Cambi, A., Mackay, F., Tarlinton, D. M., Figdor, C. G. & Wright, M. D., 2012, In : Science Signaling. 5, 250 (Art. ID: ra82), p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

49 Citations (Scopus)

The Zinc-finger protein ASCIZ regulates B cell development via DYNLL1 and Bim

Jurado, S., Gleeson, K., O'Donnell, K., Izon, D. J., Walkley, C. R., Strasser, A., Tarlinton, D. M. & Heierhorst, J., Aug 2012, In : Journal of Experimental Medicine. 209, 9, p. 1629-1639 11 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Through a glass less darkly: Apoptosis and the germinal center response to antigen

Peperzak, V., Vikstrom, I. B. & Tarlinton, D. M., May 2012, In : Immunological Reviews. 247, 1, p. 93-106 14 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)
2011

A role for Blimp1 in the transcriptional network controlling natural killer cell maturation

Kallies, A., Carotta, S., Huntington, N. D., Bernard, N. J., Tarlinton, D. M., Smyth, M. J. & Nutt, S. L., 10 Feb 2011, In : Blood. 117, 6, p. 1869-1879 11 p.

Research output: Contribution to journalArticleResearchpeer-review

92 Citations (Scopus)

B cell memory and the role of apoptosis in its formation

Vikstrom, I. B. & Tarlinton, D. M., Jun 2011, In : Molecular Immunology. 48, 11, p. 1301-1306 6 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

7 Citations (Scopus)

B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells

Lee, S. K., Rigby, R. J., Zotos, D., Tsai, L. M., Kawamoto, S., Marshall, J. L., Ramiscal, R. R., Chan, T. D., Gatto, D., Brink, R., Yu, D., Fagarasan, S., Tarlinton, D. M., Cunningham, A. F. & Vinuesa, C. G., 2011, In : Journal of Experimental Medicine. 208, 7, p. 1377 - 1388 12 p.

Research output: Contribution to journalArticleResearchpeer-review

151 Citations (Scopus)

Bcl6: Where too much complexity is barely enough

Tarlinton, D. M., Aug 2011, In : European Journal of Immunology. 41, 8, p. 2148-2151 4 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

2 Citations (Scopus)

Genetic segregation of inflammatory lung disease and autoimmune disease severity in SHIP-1-/- mice

Maxwell, M., Duan, M., Armes, J., Anderson, G., Tarlinton, D. & Hibbs, M., 2011, In : Journal of Immunology. 186, 12, p. 7164 - 7175 12 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

Germinal center B and follicular helper T cells: Siblings, cousins or just good friends?

Nutt, S. L. & Tarlinton, D., 2011, In : Nature Immunology. 12, 6, p. 472 - 477 6 p.

Research output: Contribution to journalArticleResearchpeer-review

140 Citations (Scopus)

Regulation of memory B-cell survival by the BH3-only protein Puma

Clybouw, C., Fischer, S., Auffredou, M. T., Hugues, P., Alexia, C., Bouillet, P., Raphael, M., Leca, G., Strasser, A., Tarlinton, D. M. & Vazquez, A., 13 Oct 2011, In : Blood. 118, 15, p. 4120-4128 9 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

SOCS3 deletion in B cells alters cytokine responses and germinal center output

Jones, S. A., White, C. A., Robb, L. G., Alexander, W. S. & Tarlinton, D. M., 2011, In : Journal of Immunology. 187, 12, p. 6318 - 6326 9 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)
2010

A gut feeling about plasmablasts

Tarlinton, D., 9 Dec 2010, In : Blood. 116, 24, p. 5083-5084 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access

Autoimmune disease in Lyn-deficient mice is dependent on an inflammatory environment established by IL-6

Tsantikos, E., Oracki, S. A., Quilici, C., Anderson, G., Tarlinton, D. & Hibbs, M., 2010, In : Journal of Immunology. 184, 3, p. 1348 - 1360 13 p.

Research output: Contribution to journalArticleResearchpeer-review

54 Citations (Scopus)

BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs

Carrington, E. M., Vikstrom, I. B., Light, A., Sutherland, R. M., Londrigan, S. L., Mason, K. D., Huang, D. C. S., Lew, A. M. & Tarlinton, D., 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 24, p. 10967 - 10971 5 p.

Research output: Contribution to journalArticleResearchpeer-review

73 Citations (Scopus)

CTLA4Ig alters the course of autoimmune disease development in Lyn -/- mice

Oracki, S. A., Tsantikos, E., Quilici, C., Light, A., Schmidt, T., Lew, A., Martin, J., Smith, K., Hibbs, M. & Tarlinton, D., 2010, In : Journal of Immunology. 184, 2, p. 757 - 763 7 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Give and take in the germinal center

Nutt, S. L. & Tarlinton, D. M., 1 Jun 2010, In : Nature Immunology. 11, 6, p. 464-466 3 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

4 Citations (Scopus)

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism

Zotos, D., Coquet, J. M., Zhang, Y., Light, A., D'Costa, K., Kallies, A., Corcoran, L. M., Godfrey, D. I., Toellner, K-M., Smyth, M. J., Nutt, S. L. & Tarlinton, D., 2010, In : Journal of Experimental Medicine. 207, 2, p. 365 - 378 14 p.

Research output: Contribution to journalArticleResearchpeer-review

451 Citations (Scopus)

Individual and overlapping roles of BH3-only proteins Bim and Bad in apoptosis of lymphocytes and platelets and in suppression of thymic lymphoma development

Kelly, PN., White, MJ., Goschnick, M., Fairfax, K., Tarlinton, D., Kinkel, S., Bouillet, P., Adams, J., Kile, B. T. & Strasser, A., 2010, In : Cell Death and Differentiation. 17, 10, p. 1655 - 1664 10 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

Mcl-1 is essential for germinal center formation and B cell memory

Vikstrom, I. B., Carotta, S., Luthje, K., Peperzak, V., Jost, P. J., Glaser, S. P., Busslinger, M., Bouillet, P., Strasser, A., Nutt, S. L. & Tarlinton, D., 2010, In : Science. 330, 6007, p. 1095 - 1099 5 p.

Research output: Contribution to journalArticleResearchpeer-review

130 Citations (Scopus)

Megakaryocytes constitute a functional component of a plasma cell niche in the bone marrow

Winter, O., Moser, K., Mohr, E., Zotos, D., Kaminski, H., Szyska, M., Roth, K., Wong, D. M., Dame, C., Tarlinton, D. M., Schulze, H., MacLennan, I. C. M. & Manz, R. A., 16 Sep 2010, In : Blood. 116, 11, p. 1867-1875 9 p.

Research output: Contribution to journalArticleResearchpeer-review

140 Citations (Scopus)

Memory B cells: Effectors of long-lived immune responses (European Journal of Immunology (2009) 39, (8) DOI 10.1002/eji.200939531)

Tangye, S. G. & Tarlinton, D. M., 1 Jan 2010, In : European Journal of Immunology. 40, 1, 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access

Plasma cell development and survival

Oracki, S. A., Walker, J., Hibbs, M., Corcoran, L. & Tarlinton, D., 2010, In : Immunological Reviews. 237, 1, p. 140 - 159 20 p.

Research output: Contribution to journalArticleResearchpeer-review

159 Citations (Scopus)
2009

Autoimmune regulator controls T cell help for pathogenetic autoantibody production in collagen-induced arthritis

Campbell, I. K., Kinkel, S. A., Drake, S. F., Van Nieuwenhuijze, A., Hubert, F. X., Tarlinton, D. M., Heath, W. R., Scott, H. S. & Wicks, I. P., 1 Jun 2009, In : Arthritis & Rheumatism. 60, 6, p. 1683-1693 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
26 Citations (Scopus)

Membrane-bound Fas ligand only is essential for Fas-induced apoptosis

O Reilly, L. A., Tai, L., Lee, L., Kruse, E. A., Grabow, S., Fairlie, W. D., Haynes, N. M., Tarlinton, D. M., Zhang, J. G., Belz, G. T., Smyth, M. J., Bouillet, P., Robb, L. & Strasser, A., 1 Oct 2009, In : Nature. 461, 7264, p. 659-663 5 p.

Research output: Contribution to journalArticleResearchpeer-review

253 Citations (Scopus)

Perturbation of the CD4 T cell compartment and expansion of regulatory T cells in autoimmune-prone Lyn-deficient mice

Tsantikos, E., Quilici, C., Harder, K. W., Wang, B., Zhu, H-J., Anderson, G., Tarlinton, D. M. & Hibbs, M., 2009, In : Journal of Immunology. 183, 4, p. 2484 - 2494 11 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)
2008

Evolution in miniature: Selection, survival and distribution of antigen reactive cells in the germinal centre

Tarlinton, D. M., 1 Feb 2008, In : Immunology and Cell Biology. 86, 2, p. 133-138 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

68 Citations (Scopus)

IL-17 drives germinal center B cells?

Tarlinton, D., 1 Feb 2008, In : Nature Immunology. 9, 2, p. 124-126 3 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

12 Citations (Scopus)

Plasma cell development: From B-cell subsets to long-term survival niches

Fairfax, K. A., Kallies, A., Nutt, S. L. & Tarlinton, D. M., 1 Feb 2008, In : Seminars in Immunology. 20, 1, p. 49-58 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

137 Citations (Scopus)

Plasma cell differentiation and survival

Tarlinton, D., Radbruch, A., Hiepe, F. & Dörner, T., 1 Apr 2008, In : Current Opinion in Immunology. 20, 2, p. 162-169 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

139 Citations (Scopus)

Sheepish B cells: Evidence for antigen-independent antibody diversification in humans and mice

Tarlinton, D., 9 Jun 2008, In : Journal of Experimental Medicine. 205, 6, p. 1251-1254 4 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access
9 Citations (Scopus)

The b-cell response to protein antigens in immunity and transplantation

Tarlinton, D. M., Batista, F. & Smith, K. G. C., 27 Jun 2008, In : Transplantation. 85, 12, p. 1698-1704 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

20 Citations (Scopus)
2007

A novel mutation in the Nfkb2 gene generates an NF-κB2 "super repressor"

Tucker, E., O'Donnell, K., Fuchsberger, M., Hilton, A. A., Metcalf, D., Greig, K., Sims, N. A., Quinn, J. M., Alexander, W. S., Hilton, D. J., Kile, B. T., Tarlinton, D. M. & Starr, R., 1 Dec 2007, In : Journal of Immunology. 179, 11, p. 7514-7522 9 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)

Antigen to the Node: B Cells Go Native

Tarlinton, D. & Lew, A., 27 Apr 2007, In : Immunity. 26, 4, p. 388-390 3 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

Open Access
3 Citations (Scopus)

Different kinetics of Blimp-1 induction in B cell subsets revealed by reporter gene

Fairfax, K. A., Corcoran, L. M., Pridans, C., Huntington, N. D., Kallies, A., Nutt, S. L. & Tarlinton, D. M., 1 Apr 2007, In : Journal of Immunology. 178, 7, p. 4104-4111 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
71 Citations (Scopus)

FcγRllb controls bone marrow plasma cell persistence and apoptosis

Xiang, Z., Cutler, A. J., Brownlie, R. J., Fairfax, K., Lawlor, K. E., Severinson, E., Walker, E. U., Manz, R. A., Tarlinton, D. M. & Smith, K. G. C., 1 Apr 2007, In : Nature Immunology. 8, 4, p. 419-429 11 p.

Research output: Contribution to journalArticleResearchpeer-review

228 Citations (Scopus)

Initiation of Plasma-Cell Differentiation Is Independent of the Transcription Factor Blimp-1

Kallies, A., Hasbold, J., Fairfax, K., Pridans, C., Emslie, D., McKenzie, B. S., Lew, A. M., Corcoran, L. M., Hodgkin, P. D., Tarlinton, D. M. & Nutt, S. L., 25 May 2007, In : Immunity. 26, 5, p. 555-566 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
170 Citations (Scopus)