1985 …2024

Research output per year

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Research Output

1985

HLA studies of highland and coastal New Guineans

Crane, G., Bhatia, K., Honeyman, M., Doran, T., Messel, N., Hakos, G., Tarlinton, D., Amos, D. B. & Bashir, H., 1 Jan 1985, In : Human Immunology. 12, 4, p. 247-260 14 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)
1986

Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma

Kleinfield, R., Hardy, R. R., Tarlinton, D., Dangl, J., Herzenberg, L. A. & Weigert, M., 1 Dec 1986, In : Nature. 322, 6082, p. 843-846 4 p.

Research output: Contribution to journalArticleResearchpeer-review

235 Citations (Scopus)
1987

Defective regulation of the phenylalanine biosynthetic operon in mutants of the phenylalanyl-tRNA synthetase operon

Borg-Olivier, S. A., Tarlinton, D. & Brown, K. D., 1 Jan 1987, In : Journal of Bacteriology. 169, 5, p. 1949-1953 5 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)
1988

Ly-1 B-cell clones similar to human chronic lymphocytic leukemias routinely develop in older normal mice and young autoimmune (New Zealand Black-related) animals

Stall, A. M., Farinas, M. C., Tarlinton, D. M., Lalor, P. A., Herzenberg, L. A., Strober, S. & Herzenberg, L. A., 1 Jan 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 19, p. 7312-7316 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
164 Citations (Scopus)

Repetitive usage of immunoglobulin VH and D gene segments in CD5+ Ly-1 B clones of (NZB x NZW)F1 mice.

Tarlinton, D., Stall, A. M. & Herzenberg, L. A., 1 Dec 1988, In : The EMBO Journal. 7, 12, p. 3705-3710 6 p.

Research output: Contribution to journalArticleResearchpeer-review

68 Citations (Scopus)
1990

Ly‐1 b cells and disease activity in (new zealand black × new zealand white)f1 mice

Carmen Fariñas, M., Stall, A. M., Solovera, J. J., Tarlinton, D. M., Herzenberg, L. A. & Strober, S., 1 Jan 1990, In : Arthritis & Rheumatism. 33, 4, p. 553-562 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
6 Citations (Scopus)
1991

CD5 B cells in the mouse

Forster, I., Gu, H., Muller, W., Schmitt, M., Tarlinton, D. & Rajewsky, K., 16 Jul 1991, In : Current topics in microbiology and immunology. 173, p. 247-251 5 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Most peripheral B cells in mice are ligand selected

Gu, H., Tarlinton, D., Müller, W., Rajewsky, K. & Förster, I., 1 Jun 1991, In : Journal of Experimental Medicine. 173, 6, p. 1357-1371 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
374 Citations (Scopus)
1992

An explanation for the defect in secretion of IgM Mott cells and their predominant occurrence in the Ly‐1 B cell compartment

Tarlinton, D., Förster, I. & Rajewsky, K., 1 Jan 1992, In : European Journal of Immunology. 22, 2, p. 531-539 9 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

T Cell‐Dependent Antibody Production by Ly‐1 B Cells

TAKI, SHINSUKE., SCHMITT, MARKUS., TARLINTON, DAVID., FÖRSTER, IRMGARD. & RAJEWSKY, KLAUS., 1 Jan 1992, In : Annals of the New York Academy of Sciences. 651, 1, p. 328-335 8 p.

Research output: Contribution to journalArticleResearchpeer-review

47 Citations (Scopus)
1993

Direct demonstration of MHC class II surface expression on murine pre-B cells

Tarlinton, D., 1 Dec 1993, In : International Immunology. 5, 12, p. 1629-1635 7 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)
1994

Absence of MHC class II expression distinguishes fetal from adult B lymphopoiesis in mice

Hayakawa, K., Tarlinton, D. & Hardy, R. R., 15 May 1994, In : Journal of Immunology. 152, 10, p. 4801-4807 7 p.

Research output: Contribution to journalArticleResearchpeer-review

53 Citations (Scopus)

B‐Cell Differentiation in the Bone Marrow and the Periphery

Tarlinton, D., 1 Jan 1994, In : Immunological Reviews. 137, 1, p. 203-229 27 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Bcl-2 increases memory B cell recruitment but does not perturb selection in germinal centers

Smith, K. G. C., Weiss, U., Rajewsky, K., Nossal, G. J. V. & Tarlinton, D. M., 1 Jan 1994, In : Immunity. 1, 9, p. 803-813 11 p.

Research output: Contribution to journalArticleResearchpeer-review

113 Citations (Scopus)
1995

B1 and B2 cells differ in their potential to switch immunoglobulin isotype

Tarlinton, D. M., McLean, M. & Nossal, G. J. V., 1 Jan 1995, In : European Journal of Immunology. 25, 12, p. 3388-3393 6 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

DH element reading frame selection is influenced by an Ig heavy chain transgene, but not by bcl-2

Tarlinton, D., Strasser, A., McLean, M. & Basten, A., 1 Dec 1995, In : Journal of Immunology. 154, 7, p. 3341-3350 10 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

FAS is highly expressed in the germinal center but is not required for regulation of the B-cell response to antigen

Smith, K. G. C., Nossal, G. J. V. & Tarlinton, D. M., 5 Dec 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 25, p. 11628-11632 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
105 Citations (Scopus)

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression

Köntgen, F., Grumont, R. J., Strasser, A., Metcalf, D., Li, R., Tarlinton, D. & Gerondakis, S., 15 Aug 1995, In : Genes & Development. 9, 16, p. 1965-1977 13 p.

Research output: Contribution to journalArticleResearchpeer-review

601 Citations (Scopus)

Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease

Hibbs, M. L., Tarlinton, D. M., Armes, J., Grail, D., Hodgson, G., Maglitto, R., Stacker, S. A. & Dunn, A. R., 20 Oct 1995, In : Cell. 83, 2, p. 301-311 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
580 Citations (Scopus)
1996

Chapter 2 The B-cell in immunity

Tarlinton, D., 1 Dec 1996, In : Principles of Medical Biology. 6, C, p. 21-46 26 p.

Research output: Contribution to journalArticleResearchpeer-review

The phenotype and fate of the antibody-forming cells of the splenic foci

Smith, K. G. C., Hewitson, T. D., Nossal, G. J. V. & Tarlinton, D. M., 1 Feb 1996, In : European Journal of Immunology. 26, 2, p. 444-448 5 p.

Research output: Contribution to journalArticleResearchpeer-review

246 Citations (Scopus)

The xid Mutation Diminishes Memory B Cell Generation but Does Not Affect Somatic Hypermutation and Selection

Ridderstad, A., Nossal, G. J. V. & Tarlinton, D. M., 15 Oct 1996, In : Journal of Immunology. 157, 8, p. 3357-3365 9 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)
1997

Adult mice with targeted mutation of the interleukin-11 receptor (IL11Ra) display normal hematopoiesis

Nandurkar, H. H., Robb, L. G., Tarlinton, D. M., Barnett, L., Kontgen, F. & Begley, C. G., 1997, In : Blood. 90, 6, p. 2148 - 2159 12 p.

Research output: Contribution to journalArticleResearchpeer-review

107 Citations (Scopus)

Affinity maturation of the primary response by V gene diversification

Tarlinton, D. M., Light, A., Nossal, G. J. V. & Smith, K. G. C., 1 Dec 1997, In : Current topics in microbiology and immunology. 229, p. 71-84 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

11 Citations (Scopus)

Antigen presentation by memory B cells: The sting is in the tail

Tarlinton, D., 18 Apr 1997, In : Science. 276, 5311, p. 374-375 2 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

24 Citations (Scopus)

Apoptosis and the B cell response to antigen

Tarlinton, D. M. & Smith, K. G. C., 1 Jan 1997, In : International Reviews of Immunology. 15, 1-2, p. 53-71 19 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

B cell memory in xid mice is Long-Lived despite reduced memory b cell frequency

Ridderstad, A. & Tarlinton, D. M., 1 Jan 1997, In : Scandinavian Journal of Immunology. 45, 6, p. 655-659 5 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Continued differentiation during a lymphopoiesis requires signals in addition to cell survival

Tarlinton, D. M., Corcoran, L. M. & Strasser, A., 22 Oct 1997, In : International Immunology. 9, 10, p. 1481-1494 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
32 Citations (Scopus)

Expression of a bcl-2 transgene reduces proliferation and slows turnover of developing B lymphocytes in vivo

O'Reilly, L. A., Harris, A. W., Tarlinton, D. M., Corcoran, L. M. & Strasser, A., 1 Dec 1997, In : Journal of Immunology. 159, 5, p. 2301-2311 11 p.

Research output: Contribution to journalArticleResearchpeer-review

76 Citations (Scopus)

Germinal centers: A second childhood for lymphocytes

Tarlinton, D., 1 Jan 1997, In : Current Biology. 7, 3

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Mice lacking both the nfκb1 and c-rel genes develop normally but exhibit an impaired production of immunoglobulins and profound defects in proliferation of B and T lymphocytes

Pohl, T., Strasser, A., Tarlinton, D., Metcalf, D. & Gerondakis, S., 1 Jan 1997, In : Immunobiology. 197, 2-4, p. 143-144 2 p.

Research output: Contribution to journalArticleResearchpeer-review

The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response

Smith, K. G. C., Light, A., Nossal, G. V. J. & Tarlinton, D., 1997, In : The EMBO Journal. 16, 11, p. 2996 - 3006 11 p.

Research output: Contribution to journalArticleResearchpeer-review

293 Citations (Scopus)
1998

Germinal centers: Getting there is half the fun

Tarlinton, D., 22 Oct 1998, In : Current Biology. 8, 21

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Germinal centers: Form and function

Tarlinton, D., 1 Jan 1998, In : Current Opinion in Immunology. 10, 3, p. 245-251 7 p.

Research output: Contribution to journalArticleResearchpeer-review

100 Citations (Scopus)

Inhibition of the B cell by CD22: A requirement for Lyn

Smith, K. G. C., Tarlinton, D. M., Doody, G. M., Hibbs, M. L. & Fearon, D. T., 2 Mar 1998, In : Journal of Experimental Medicine. 187, 5, p. 807-811 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
202 Citations (Scopus)

Kinetics of establishing the memory B cell population as revealed by CD38 expression

Ridderstad, A. & Tarlinton, D. M., 15 May 1998, In : Journal of Immunology. 160, 10, p. 4688-4695 8 p.

Research output: Contribution to journalArticleResearchpeer-review

111 Citations (Scopus)
1999

Genetic evidence for Lyn as a negative regulator of IL-4 signaling

Janas, M. L., Hodgkin, P., Hibbs, M. & Tarlinton, D., 20 Oct 1999, In : Journal of Immunology. 163, 8, p. 4192-4198 7 p.

Research output: Contribution to journalArticleResearchpeer-review

38 Citations (Scopus)
2000

Affinity maturation in the B-cell response to antigen

Tarlinton, D., Light, A., Smith, K. & Nossal, G. J. V., 1 Jan 2000, In : Immunologist. 8, 1-2, p. 9-11 3 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

bcl-2 Transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells

Smith, K. G. C., Light, A., O'Reilly, L. A., Ang, S. M., Strasser, A. & Tarlinton, D., 2000, In : Journal of Experimental Medicine. 191, 3, p. 475 - 484 10 p.

Research output: Contribution to journalArticleResearchpeer-review

150 Citations (Scopus)

Dissecting affinity maturation: A model explaining selection of antibody-forming cells and memory B cells in the germinal centre

Tarlinton, D. M. & Smith, K. G. C., 1 Jan 2000, In : Immunology Today. 21, 9, p. 436-441 6 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

111 Citations (Scopus)

Erratum: Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAm-1 in specialized endothelial cells of the viscera (Developmental Biology (2000) 224:232 (152-167))

Wang, C. C., Biben, C., Robb, L., Nassir, F., Barnett, L., Davidson, N. O., Koentgen, F., Tarlinton, D. & Harvey, R. P., 15 Nov 2000, In : Developmental Biology. 227, 2, 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access

Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera

Wang, C. C., Biben, C., Robb, L., Nassir, F., Barnett, L., Davidson, N. O., Koentgen, F., Tarlinton, D. & Harvey, R. P., 15 Aug 2000, In : Developmental Biology. 224, 2, p. 152-167 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
51 Citations (Scopus)

Single cell sorting and cloning

Battye, F. L., Light, A. & Tarlinton, D. M., 21 Sep 2000, In : Journal of Immunological Methods. 243, 1-2, p. 25-32 8 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)
2001

Defective gp130-mediated Signal Transducer and Activator of Transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation

Ernst, M., Inglese, M., Waring, P., Campbell, I. K., Bao, S., Clay, F. J., Alexander, W. S., Wicks, I. P., Tarlinton, D. M., Novak, U., Heath, J. K. & Dunn, A. R., 16 Jul 2001, In : Journal of Experimental Medicine. 194, 2, p. 189-203 15 p.

Research output: Contribution to journalArticleResearchpeer-review

195 Citations (Scopus)
2002

Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity

Hibbs, M. L., Harder, K. W., Armes, J., Kountouri, N., Quilici, C., Casagranda, F., Dunn, A. R. & Tarlinton, D. M., 16 Dec 2002, In : Journal of Experimental Medicine. 196, 12, p. 1593-1604 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
120 Citations (Scopus)

The absence of Tssc6, a member of the tetraspanin superfamily, does not affect lymphoid development but enhances in vitro T-cell proliferative responses

Tarrant, J. M., Groom, J., Metcalf, D., Li, R., Borobokas, B., Wright, M. D., Tarlinton, D. & Robb, L., 9 Jul 2002, In : Molecular and Cellular Biology. 22, 14, p. 5006-5018 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
57 Citations (Scopus)

The activation and subsequent regulatory roles of Lyn and CD19 after B cell receptor ligation are independent

Xu, Y., Beavitt, S. J. E., Harder, K. W., Hibbs, M. L. & Tarlinton, D. M., 15 Dec 2002, In : Journal of Immunology. 169, 12, p. 6910-6918 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
27 Citations (Scopus)

The combined absence of NF-κB1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells

Pohl, T., Gugasyan, R., Grumont, R. J., Strasser, A., Metcalf, D., Tarlinton, D., Sha, W., Baltimore, D. & Gerondakis, S., 2 Apr 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 7, p. 4514-4519 6 p.

Research output: Contribution to journalArticleResearchpeer-review

86 Citations (Scopus)

The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes

Croker, B. A., Tarlinton, D. M., Cluse, L. A., Tuxen, A. J., Light, A., Yang, F. C., Williams, D. A. & Roberts, A. W., 1 Apr 2002, In : Journal of Immunology. 168, 7, p. 3376-3386 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
91 Citations (Scopus)
2003

Architectural defects in the spleens of Nkx2-3-deficient mice are intrinsic and associated with defects in both B cell maturation and T cell-dependent immune responses

Tarlinton, D., Light, A., Metcalf, D., Harvey, R. P. & Robb, L., 15 Apr 2003, In : Journal of Immunology. 170, 8, p. 4002-4010 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
33 Citations (Scopus)