1985 …2024

Research output per year

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Research Output

2020

Hhex regulates murine lymphoid progenitor survival independently of Stat5 and Cdkn2a

Jackson, J. T., O'Donnell, K., Light, A., Goh, W., Huntington, N. D., Tarlinton, D. M. & McCormack, M. P., 23 Feb 2020, (Accepted/In press) In : European Journal of Immunology. 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2019

B cells still front and centre in immunology

Tarlinton, D., 1 Feb 2019, In : Nature Reviews Immunology. 19, 2, p. 85-86 2 p.

Research output: Contribution to journalArticleOtherpeer-review

3 Citations (Scopus)

Innate Immunity in the Central Nervous System: A Missing Piece of the Autoimmune Encephalitis Puzzle?

Wesselingh, R., Butzkueven, H., Buzzard, K., Tarlinton, D., O'Brien, T. J. & Monif, M., 1 Jan 2019, In : Frontiers in Immunology. 10, 14 p., 2066.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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2 Citations (Scopus)
2018

Atypical chemokine receptor 4 shapes activated B cell fate

Kara, E. E., Bastow, C. R., McKenzie, D. R., Gregor, C. E., Fenix, K. A., Babb, R., Norton, T. S., Zotos, D., Rodda, L. B., Hermes, J. R., Bourne, K., Gilchrist, D. S., Nibbs, R. J., Alsharifi, M., Vinuesa, C. G., Tarlinton, D. M., Brink, R., Hill, G. R., Cyster, J. G., Comerford, I. & 1 others, McColl, S. R., 1 Mar 2018, In : The Journal of Experimental Medicine. 215, 3, p. 801-813 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)

Lyn, lupus, and (B) lymphocytes, a lesson on the critical balance of kinase signaling in immunity

Brodie, E. J., Infantino, S., Low, M. S. Y. & Tarlinton, D. M., 1 Mar 2018, In : Frontiers in Immunology. 9, MAR, 10 p., 401.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells

Zhang, Y., Tech, L., George, L. A., Acs, A., Durrett, R. E., Hess, H., Walker, L. S. K., Tarlinton, D. M., Fletcher, A. L., Hauser, A. E. & Toellner, K. M., 1 Apr 2018, In : The Journal of Experimental Medicine. 215, 4, p. 1227-1243 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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25 Citations (Scopus)

Proapoptotic BIM impacts B lymphoid homeostasis by limiting the survival of mature B cells in a cell-autonomous manner

Liu, R., King, A., Bouillet, P., Tarlinton, D. M., Strasser, A. & Heierhorst, J., 22 Mar 2018, In : Frontiers in Immunology. 8, MAR, 10 p., 592.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)
2017

Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo

Carrington, E. M., Zhan, Y., Brady, J. L., Zhang, J. G., Sutherland, R. M., Anstee, N. S., Schenk, R. L., Vikstrom, I. B., Delconte, R. B., Segal, D., Huntington, N. D., Bouillet, P., Tarlinton, D. M., Huang, D. C. S., Strasser, A., Cory, S., Herold, M. J. & Lew, A. M., 1 May 2017, In : Cell Death and Differentiation. 24, 5, p. 878-888 11 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation

Infantino, S., Light, A., O'donnell, K., Bryant, V., Avery, D. T., Elliott, M., Tangye, S. G., Belz, G., Mackay, F., Richard, S. & Tarlinton, D., 1 Dec 2017, In : Nature Communications. 8, 1, 12 p., 891.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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9 Citations (Scopus)

c-Myb Regulates the T-Bet-Dependent Differentiation Program in B Cells to Coordinate Antibody Responses

Piovesan, D., Tempany, J., Di Pietro, A., Baas, I., Yiannis, C., O'Donnell, K., Chen, Y., Peperzak, V., Belz, G. T., Mackay, C. R., Smyth, G. K., Groom, J. R., Tarlinton, D. M. & Good-Jacobson, K. L., 18 Apr 2017, In : Cell Reports. 19, 3, p. 461-470 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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19 Citations (Scopus)

Dynein light chain regulates adaptive and innate B cell development by distinctive genetic mechanisms

King, A., Li, L., Wong, D. M., Liu, R., Bamford, R., Strasser, A., Tarlinton, D. M. & Heierhorst, J., 1 Sep 2017, In : PLoS Genetics. 13, 9, e1007010.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)

Editorial overview: Germinal centers and memory B-cells: from here to eternity

Tarlinton, D. & Victora, G., 1 Apr 2017, In : Current Opinion in Immunology. 45, p. v-viii 4 p.

Research output: Contribution to journalEditorialOtherpeer-review

3 Citations (Scopus)

Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB

Willis, S. N., Tellier, J., Liao, Y., Trezise, S., Light, A., O'Donnell, K., Garrett-Sinha, L. A., Shi, W., Tarlinton, D. M. & Nutt, S. L., 1 Dec 2017, In : Nature Communications. 8, 1, 14 p., 1426.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
11 Citations (Scopus)

HIV Vaccines: One Step Closer

Low, M. S. Y. & Tarlinton, D., 1 Jan 2017, In : Trends in Molecular Medicine. 23, 1, p. 1-3 3 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

IL4 and IL21 cooperate to induce the high Bcl6 protein level required for germinal center formation

Chevrier, S., Kratina, T., Emslie, D., Tarlinton, D. M. & Corcoran, L. M., 1 Nov 2017, In : Immunology and Cell Biology. 95, 10, p. 925-932 8 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

The BTG2-PRMT1 module limits pre-B cell expansion by regulating the CDK4-Cyclin-D3 complex

Dolezal, E., Infantino, S., Drepper, F., Börsig, T., Singh, A., Wossning, T., Fiala, G. J., Minguet, S., Warscheid, B., Tarlinton, D. M., Jumaa, H., Medgyesi, D. & Reth, M., 19 Jul 2017, In : Nature Immunology. 18, 8, p. 911-920 10 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

The life and death of immune cell types: The role of BCL-2 anti-apoptotic molecules

Carrington, E. M., Tarlinton, D. M., Gray, D. H., Huntington, N. D., Zhan, Y. & Lew, A. M., 1 Nov 2017, In : Immunology and Cell Biology. 95, 10, p. 870-877 8 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

12 Citations (Scopus)
2016

Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development

Gloury, R., Zotos, D., Zuidscherwoude, M., Masson, F., Liao, Y., Hasbold, J., Corcoran, L. M., Hodgkin, P. D., Belz, G. T., Shi, W., Nutt, S. L., Tarlinton, D. M. & Kallies, A., 1 May 2016, In : The Journal of Experimental Medicine. 213, 6, p. 1095-1111 17 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Glucocorticoid-induced leucine zipper (GILZ) inhibits B cell activation in systemic lupus erythematosus

Jones, S. A., Toh, A. E. J., Odobasic, D., Oudin, M-A. V., Cheng, Q., Lee, J. P. W., White, S. J., Russ, B. E., Infantino, S., Light, A., Tarlinton, D. M., Harris, J. & Morand, E. F., 2016, In : Annals of the Rheumatic Diseases. 75, 4, p. 739-747 9 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Innate allorecognition results in rapid accumulation of monocyte-derived dendritic cells

Chow, K. V., Delconte, R. B., Huntington, N. D., Tarlinton, D. M., Sutherland, R. M., Zhan, Y. & Lew, A. M., 1 Sep 2016, In : Journal of Immunology. 197, 5, p. 2000-2008 9 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL

Vikstrom, I. B., Slomp, A., Carrington, E. M., Moesbergen, L. M., Chang, C., Kelly, G. L., Glaser, S. P., Jansen, J. H. M., Leusen, J. H. W., Strasser, A., Huang, D. C. S., Lew, A. M., Peperzak, V. & Tarlinton, D. M., 25 Aug 2016, In : Cell Death and Disease. 7, 8, e2345.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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24 Citations (Scopus)

Regulation of germinal center responses, memory B cells and plasma cell formation-an update

Corcoran, L. M. & Tarlinton, D. M., 1 Apr 2016, In : Current Opinion in Immunology. 39, p. 59-67 9 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

38 Citations (Scopus)

Targeting plasma cells: Are we any closer to a panacea for diseases of antibody-secreting cells?

Low, M., Infantino, S., Grigoriadis, G. & Tarlinton, D., 1 Mar 2016, In : Immunological Reviews. 270, 1, p. 78-94 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

3 Citations (Scopus)

The Transcription Factor ASCIZ and Its Target DYNLL1 Are Essential for the Development and Expansion of MYC-Driven B Cell Lymphoma

Wong, D. M., Li, L., Jurado, S., King, A., Bamford, R., Wall, M., Walia, M. K., Kelly, G. L., Walkley, C. R., Tarlinton, D. M., Strasser, A. & Heierhorst, J., 16 Feb 2016, In : Cell Reports. 14, 6, p. 1488-1499 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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11 Citations (Scopus)
2015

c-Myb is required for plasma cell migration to bone marrow after immunization or infection

Good-Jacobson, K. L., O'Donnell, K., Belz, G. T., Nutt, S. L. & Tarlinton, D., 2015, In : The Journal of Experimental Medicine. 212, 7, p. 1001 - 1009 9 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

How many memories does it take to make an SLE flare?

Tarlinton, D. M. & Smith, K. G. C., 20 Jul 2015, In : Nature Immunology. 16, 7, p. 685-687 3 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

1 Citation (Scopus)

Manipulation of B-cell responses with histone deacetylase inhibitors

Waibel, M., Christiansen, A. J., Hibbs, M., Shortt, J., Jones, S., Simpson, I., Light, A., O'Donnell, K., Morand, E. F., Tarlinton, D. M., Johnstone, R. W. & Hawkins, E., 2015, In : Nature Communications. 6, (Art. No: 6838), p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
38 Citations (Scopus)

Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells

Carrington, E. M., Zhang, J. G., Sutherland, R. M., Vikstrom, I. B., Brady, J. L., Soo, P., Vremec, D., Allison, C., Lee, E. F., Fairlie, W. D., Bouillet, P., Grabow, S., Ottina, E., Herold, M. J., Pellegrini, M., Huang, D. C. S., Tarlinton, D. M., Strasser, A., Lew, A. M. & Zhan, Y., 31 Mar 2015, In : Proceedings of the National Academy of Sciences. 112, 13, p. 4044-4049 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
28 Citations (Scopus)

Targeting antigen to Clec9A primes follicular Th cell memory responses capable of robust recall

Kato, Y., Zaid, A., Davey, G. M., Mueller, S. N., Nutt, S. L., Zotos, D., Tarlinton, D., Shortman, K., Lahoud, M. H., Heath, W. R. & Caminschi, I., 2015, In : Journal of Immunology. 195, 3, p. 1006 - 1014 9 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

The generation of antibody-secreting plasma cells

Nutt, S. L., Hodgkin, P. D., Tarlinton, D. M. & Corcoran, L. M., 2015, In : Nature Reviews Immunology. 15, 3, p. 160 - 171 12 p.

Research output: Contribution to journalArticleOtherpeer-review

348 Citations (Scopus)

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells

Shi, W., Liao, Y., Willis, S. N., Taubenheim, N., Inouye, M., Tarlinton, D. M., Smyth, G. K., Hodgkin, P. D., Nutt, S. L. & Corcoran, L. M., 2015, In : Nature Immunology. 16, 6, p. 663 - 673 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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131 Citations (Scopus)
2014

B Cell Memory and Plasma Cell Development

Takemori, T., Tarlinton, D., Hiepe, F. & Andreas, R., 15 Dec 2014, Molecular Biology of B Cells. Alt, F. W., Honjo, T., Radbruch, A. & Reth, M. (eds.). 2nd ed. London UK: Academic Press, p. 227-249 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2 Citations (Scopus)

CD19 differentially regulates BCR signalling through the recruitment of PI3K

Xu, Y., Fairfax, K., Light, A., Huntington, N. D. & Tarlinton, D. M., 2014, In : Autoimmunity. 47, 7, p. 430 - 437 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

8 Citations (Scopus)

Fas ligand-mediated immune surveillance by T cells is essential for the control of spontaneous B cell lymphomas

Afshar-Sterle, S., Zotos, D., Bernard, N. J., Scherger, A. K., Rödling, L., Alsop, A. E., Walker, J. A., Masson, F., Belz, G. T., Corcoran, L. M., O'Reilly, L. A., Strasser, A., Smyth, M. J., Johnstone, R., Tarlinton, D. M., Nutt, S. L. & Kallies, A., 2014, In : Nature Medicine. 20, 3, p. 283-290 8 p.

Research output: Contribution to journalArticleResearchpeer-review

52 Citations (Scopus)

IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell-dependent antigen

Jacque, E., Schweighoffer, E., Visekruna, A., Papoutsopoulou, S., Janzen, J., Zillwood, R., Tarlinton, D. M., Tybulewicz, V. L. J. & Ley, S. C., 2014, In : The Journal of Experimental Medicine. 211, 10, p. 2085-2101 17 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Immunology: To affinity and beyond

Tarlinton, D. M., 2014, In : Nature. 509, 7502, p. 573-574 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

3 Citations (Scopus)

Regulation of germinal center responses and B-cell memory by the chromatin modifier MOZ

Good-Jacobson, K. L., Chen, Y., Voss, A. K., Smyth, G. K., Thomas, T. & Tarlinton, D., 2014, In : Proceedings of the National Academy of Sciences. 111, 26, p. 9585 - 9590 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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26 Citations (Scopus)

The BTB-ZF transcription factor Zbtb20 is driven by Irf4 to promote plasma cell differentiation and longevity

Chevrier, S., Emslie, D., Shi, W., Kratina, T., Wellard, C., Karnowski, A., Erikci, E., Smyth, G. K., Chowdhury, K., Tarlinton, D. & Corcoran, L. M., 2014, In : The Journal of Experimental Medicine. 211, 5, p. 827-840 14 p.

Research output: Contribution to journalArticleResearchpeer-review

48 Citations (Scopus)

The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation

Carotta, S., Willis, S. N., Hasbold, J., Inouye, M., Pang, S. H. M., Emslie, D., Light, A., Chopin, M., Shi, W., Wang, H., Morse III, H. C., Tarlinton, D. M., Corcoran, L. M., Hodgkin, P. D. & Nutt, S. L., 6 Oct 2014, In : The Journal of Experimental Medicine. 211, 11, p. 2169-2181 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
62 Citations (Scopus)

The tyrosine kinase Lyn limits the cytokine responsiveness of plasma cells to restrict their accumulation in mice

Infantino, S., Jones, S. A., Walker, J. A., Maxwell, M. J., Light, A., O'Donnell, K., Tsantikos, E., Peperzak, V., Phesse, T. J., Ernst, M. R., Mackay-Fisson, F., Hibbs, M., Fairfax, K. & Tarlinton, D. M., 2014, In : Science Signaling. 7, 338, p. 1 - 10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Transcription factor IRF4 regulates germinal center cell formation through a B cell-intrinsic mechanism

Willis, S. N., Good-Jacobson, K. L., Curtis, J. M., Light, A., Tellier, J., Shi, W., Smyth, G. K., Tarlinton, D. M., Belz, G. T., Corcoran, L. M., Kallies, A. & Nutt, S. L., 2014, In : Journal of Immunology. 192, 7, p. 3200-3206 7 p.

Research output: Contribution to journalArticleResearchpeer-review

52 Citations (Scopus)
2013

CCR6 is transiently upregulated on B cells after activation and modulates the germinal center reaction in the mouse

Wiede, F., Fromm, P., Comerford, I., Kara, E., Bannan, J., Schuh, W., Ranasinghe, C., Tarlinton, D. M., Winkler, T., McColl, S. R. & Korner, H., 2013, In : Immunology and Cell Biology. 91, 5, p. 335 - 339 5 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Diversity among memory B cells: Origin, consequences, and utility

Tarlinton, D. & Good-Jacobson, K. L., 2013, In : Science. 341, 6151, p. 1205 - 1211 7 p.

Research output: Contribution to journalArticleResearchpeer-review

119 Citations (Scopus)

Erratum: Mcl-1 is essential for the survival of plasma cells (Nature Immunology (2013) 14 (290-297))

Peperzak, V., Vikström, I., Walker, J. G., Glaser, S. P., Lepage, M., Coquery, C. M., Erickson, L. D., Fairfax, K., Mackay, F., Strasser, A., Nutt, S. L. & Tarlinton, D. M., Aug 2013, In : Nature Immunology. 14, 8, p. 877 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

1 Citation (Scopus)

Evolution of B cell responses to Clec9A-targeted antigen

Park, H-Y., Light, A., Lahoud, M., Caminschi, I., Tarlinton, D. M. & Shortman, K., 2013, In : Journal of Immunology. 191, 10, p. 4919 - 4925 7 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Feeling a Little SYK after Mixing BAFF with BCR

Infantino, S. & Tarlinton, D. M., 21 Mar 2013, In : Immunity. 38, 3, p. 406-408 3 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

4 Citations (Scopus)

Interleukin-6 trans-signaling exacerbates inflammation and renal pathology in lupus-prone mice

Tsantikos, E., Maxwell, M. J., Putoczki, T. L., Ernst, M. R., Rose-John, S., Tarlinton, D. M. & Hibbs, M., 2013, In : Arthritis and Rheumatism. 65, 10, p. 2691 - 2702 12 p.

Research output: Contribution to journalArticleOther

30 Citations (Scopus)

Mcl-1 is essential for the survival of plasma cells

Peperzak, V., Vikstrom, I., Walker, J. A., Glaser, S. P., Le Page, M., Coquery, C. M., Erickson, L. D., Fairfax, K., Mackay-Fisson, F., Strasser, A., Nutt, S. L. & Tarlinton, D. M., 2013, In : Nature Immunology. 14, 3, p. 290-297 8 p.

Research output: Contribution to journalArticleResearchpeer-review

152 Citations (Scopus)

Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity

Hawkins, E. D., Oliaro, J., Kallies, A., Belz, G. T., Filby, A., Hogan, T., Haynes, N. M., Ramsbottom, K. M., Van Ham, V., Kinwell, T., Seddon, B., Davies, D., Tarlinton, D., Lew, A. M., Humbert, P. O. & Russell, S. M., 2013, In : Nature Communications. 4, 1801.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
50 Citations (Scopus)
2012

Activated mouse B cells lack expression of granzyme B

Hagn, M., Belz, G. T., Kallies, A., Sutton, V. R., Thia, K. Y. T., Tarlinton, D. M., Hawkins, E. D. & Trapani, J. A., 15 Apr 2012, In : Journal of Immunology. 188, 8, p. 3886-3892 7 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)