20082024
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Research Output 2008 2019

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2019

Enzalutamide with standard first-line therapy in metastatic prostate cancer

Davis, I. D., Martin, A. J., Stockler, M. R., Begbie, S., Chi, K. N., Chowdhury, S., Coskinas, X., Frydenberg, M., Hague, W. E., Horvath, L. G., Joshua, A. M., Lawrence, N. J., Marx, G., McCaffrey, J., McDermott, R., McJannett, M., North, S. A., Parnis, F., Parulekar, W., Pook, D. W. & 13 othersReaume, M. N., Sandhu, S. K., Tan, A., Tan, T. H., Thomson, A., Tu, E., Vera-Badillo, F., Williams, S. G., Yip, S., Zhang, A. Y., Zielinski, R. R., Sweeney, C. J. & for the ENZAMET Trial Investigators and the Australian and New Zealand Urogenital and Prostate Cancer Trials Group, 11 Jul 2019, In : New England Journal of Medicine. 381, 2, p. 121-131 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Establishing a cryopreservation protocol for patient-derived xenografts of prostate cancer

Porter, L. H., Lawrence, M. G., Wang, H., Clark, A. K., Bakshi, A., Obinata, D., Goode, D., Papargiris, M., Clouston, D., Ryan, A., Norden, S., Corey, E., Nelson, P. S., Isaacs, J. T., Grummet, J., Kourambas, J., Sandhu, S., Murphy, D. G., Pook, D., Frydenberg, M. & 2 othersTaylor, R. A. & Risbridger, G. P., 1 Aug 2019, In : Prostate. 79, 11, p. 1326-1337 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Prognostic Utility of a Whole-blood Androgen Receptor-based Gene Signature in Metastatic Castration-resistant Prostate Cancer

Kwan, E. M., Fettke, H., Docanto, M. M., To, S. Q., Bukczynska, P., Mant, A., Pook, D., Ng, N., Graham, L. J. K., Mangiola, S., Segelov, E., Mahon, K., Davis, I. D., Parente, P., Pezaro, C., Todenhöfer, T., Horvath, L. G. & Azad, A. A., 15 May 2019, (Accepted/In press) In : European Urology Focus. 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Timing of brain metastases development in metastatic renal cell cancer patients treated with targeted therapies and survival outcomes: An Australian multicenter study

Ha, F. J., Spain, L., Dowling, A., Kwan, E. M., Pezaro, C., Day, D., Chia, P. L., Tran, B., Pook, D. & Weickhardt, A. J., 30 Jan 2019, (Accepted/In press) In : Asia-Pacific Journal of Clinical Oncology. 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy

Lawrence, M. G., Obinata, D., Sandhu, S., Selth, L. A., Wong, S. Q., Porter, L. H., Lister, N., Pook, D., Pezaro, C. J., Goode, D. L., Rebello, R. J., Clark, A. K., Papargiris, M., Van Gramberg, J., Hanson, A. R., Banks, P., Wang, H., Niranjan, B., Keerthikumar, S., Hedwards, S. & 32 othersHuglo, A., Yang, R., Henzler, C., Li, Y., Lopez-Campos, F., Castro, E., Toivanen, R., Azad, A., Bolton, D., Goad, J., Grummet, J., Harewood, L., Kourambas, J., Lawrentschuk, N., Moon, D., Murphy, D. G., Sengupta, S., Snow, R., Thorne, H., Mitchell, C., Pedersen, J., Clouston, D., Norden, S., Ryan, A., Dehm, S. M., Tilley, W. D., Pearson, R. B., Hannan, R. D., Frydenberg, M., Furic, L., Taylor, R. A. & Risbridger, G. P., 1 Nov 2018, In : European Urology. 74, 5, p. 562-572 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2017

Prevalence of systemic anticancer therapy for patients within the last 30 days of life: experience in a private hospital oncology group

Wein, L., Rowe, C., Brady, B., Handolias, D., Lipton, G. L., Pook, D., Stanley, R. & Haines, I., 1 Mar 2017, In : Internal Medicine Journal. 47, 3, p. 280-283 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2015

Establishment of primary patient-derived xenografts of palliative TURP specimens to study castrate-resistant prostate cancer

Lawrence, M. G., Pook, D. W., Wang, H., Porter, L. H., Frydenberg, M., Kourambas, J., Appu, S., Poole, C., Beardsley, E. K., Ryan, A. J., Norden, S., Papargiris, M., Risbridger, G. P. & Taylor, R. A., 2015, In : Prostate. 75, 13, p. 1475 - 1483 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Patient-derived Xenografts Reveal that Intraductal Carcinoma of the Prostate Is a Prominent Pathology in BRCA2 Mutation Carriers with Prostate Cancer and Correlates with Poor Prognosis

Risbridger, G. P., Taylor, R. A., Clouston, D., Sliwinski, A., Thorne, H. J., Hunter, S. M., Li, J., Mitchell, G. W. E., Murphy, D. G. M., Frydenberg, M., Pook, D. W., Pedersen, J. S., Toivanen, R., Wang, H., Papargiris, M., Lawrence, M. G. & Bolton, D. M., 1 Mar 2015, In : European Urology. 67, 3, p. 496 - 503 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2014

A pro-tumourigenic loop at the human prostate tumour interface orchestrated by oestrogen, CXCL12 and mast cell recruitment

Ellem, S. J., Taylor, R. A., Furic, L., Larsson, O., Frydenberg, M., Pook, D. W., Pedersen, J. S., Cawsey, B., Trotta, A., Need, E. F., Buchanan, G. & Risbridger, G. P., 2014, In : Journal of Pathology. 234, 1, p. 86 - 98 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Rare synchronous metastases of renal cell carcinoma

Rajarubendra, N., Pook, D., Frydenberg, M. & Appu, S., 2014, In : Urology Annals. 6, 2, p. 157-158 2 p.

Research output: Contribution to journalArticleOtherpeer-review

2013

A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer

Clark, A. K., Taubenberger, A. V., Taylor, R. A., Niranjan, B., Chea, Z. Y., Zotenko, E., Sieh, S., Pedersen, J. S., Norden, S., Frydenberg, M., Grummet, J., Pook, D. W., Stirzaker, C., Clark, S., Lawrence, M. G., Ellem, S. J., Hutmacher, D. & Risbridger, G. P., 2013, In : Biomaterials. 34, 20, p. 4777 - 4785 9 p.

Research output: Contribution to journalArticleResearchpeer-review

A preclinical xenograft model identifies castration-tolerant cancer-repopulating cells in localized prostate tumors

Toivanen, R., Frydenberg, M., Murphy, D., Pedersen, J. S., Ryan, A., Pook, D. W., Berman, D. M., Taylor, R. A. & Risbridger, G. P., 2013, In : Science Translational Medicine. 5, 187 (Art. No.:187ra71), p. 1 - 7 7 p.

Research output: Contribution to journalArticleResearchpeer-review

A preclinical xenograft model of prostate cancer using human tumors

Lawrence, M. G., Taylor, R. A., Toivanen, R., Pedersen, J. S., Norden, S., Pook, D. W., Frydenberg, M., Australian Prostate Cancer BioResource, Papargiris, M., Niranjan, B., Richards, M. G., Wang, H., Collins, A. T., Maitland, N. J. & Risbridger, G. P., 2013, In : Nature Protocols. 8, 5, p. 836 - 848 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Regulation of the transcriptional coactivator FHL2 licenses activation of the androgen receptor in castrate-resistant prostate cancer

Mcgrath, M. J., Binge, L. C., Sriratana, A., Wang, H., Robinson, P. A., Pook, D. W., Fedele, C. G., Brown, S., Dyson, J. M., Cottle, D. L., Cowling, B. S., Niranjan, B., Risbridger, G. P. & Mitchell, C. A., 2013, In : Cancer Research. 73, 16, p. 5066 - 5079 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2012

Breaking through a roadblock in prostate cancer research: An update on human model systems

Toivanen, R., Taylor, R. A., Pook, D. W., Ellem, S. J. & Risbridger, G. P., 2012, In : Journal of Steroid Biochemistry and Molecular Biology. 131, 3-5, p. 122 - 131 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2008

Targeted therapies in renal cell carcinoma

Pook, D. & Davis, I. D., 1 Nov 2008, In : Cancer Forum. 32, 3, p. 155-158 4 p.

Research output: Contribution to journalArticleResearchpeer-review