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David Pook

Dr

20082024
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Personal profile

Biography

Dr David Pook is a Medical Oncologist working with the Prostate Cancer Research Program in the Department of Anatomy and Developmental Biology. Dr Pook's research work is directed towards developing a better understanding of castrate resistant prostate cancer. He is also a lead investigator in the VCA funded CAPTIV prostate cancer research program.

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Projects 2011 2024

A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial Testing Ipatasertib Plus Abiraterone Plus Prednisone/Prednisolone, Relative To Placebo Plus Abiraterone Plus Prednisone/Prednisolone In Adult Male Patients With Asymptomatic Or Mildly Symptomatic, Previously Untreated, Metastatic Castrate-Resistant Prostate Cancer

Pook, D.

6/05/19 → 5/05/24

Project: Research

A Phase II trial of single agent cabozantinib in patients with locally advanced or metastatic non-clear cell renal cell carcinoma post immunotherapy or who are unsuitable for immunotherapy

Pook, D.

30/04/19 → 29/04/24

Project: Research

Denosumab and Pembrolizumab in Renal Cell Carcinoma: A Phase II Trial

Pook, D.

25/03/19 → 24/03/24

Project: Research

A Phase 2, Fast Real-time Assessment of Combination Therapies in Immuno-Oncology Study in Participants with Advanced Renal Cell Carcinoma (FRACTION-RCC)

Pook, D.

21/02/19 → 20/02/24

Project: Research

A Phase 3, Randomized, Open-Label Study of Nivolumab Combined with Ipilimumab Versus Sunitinib Monotherapy in Subjects with Previously Untreated, Advanced or Metastatic Renal Cell Carcinoma

Pook, D.

12/02/19 → 11/02/24

Project: Research

Research Output 2008 2019

Timing of brain metastases development in metastatic renal cell cancer patients treated with targeted therapies and survival outcomes: An Australian multicenter study

Ha, F. J., Spain, L., Dowling, A., Kwan, E. M., Pezaro, C., Day, D., Chia, P. L., Tran, B., Pook, D. & Weickhardt, A. J., 30 Jan 2019, (Accepted/In press) In : Asia-Pacific Journal of Clinical Oncology. 6 p.

Research output: Contribution to journal › Article › Research › peer-review

Whole blood FOLH1 mRNA expression and treatment response in metastatic castration-resistant prostate cancer (mCRPC)

Kwan, E. M., To, S. Q. G., Fettke, H. C., Docanto, M., Bukczynska, P., Mant, A. M., Pook, D. W., Ng, N., Graham, L. J. K., Segelov, E., Mahon, K. L., Davis, I., Parente, P., Pezaro, C., Horvath, L. G. & Azad, A., 1 Mar 2019, In : Journal of Clinical Oncology. 37, 7 Suppl, p. 188 1 p.

Research output: Contribution to journal › Meeting Abstract › Other › peer-review

Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy

Lawrence, M. G., Obinata, D., Sandhu, S., Selth, L. A., Wong, S. Q., Porter, L. H., Lister, N., Pook, D., Pezaro, C. J., Goode, D. L., Rebello, R. J., Clark, A. K., Papargiris, M., Van Gramberg, J., Hanson, A. R., Banks, P., Wang, H., Niranjan, B., Keerthikumar, S., Hedwards, S. & 32 othersHuglo, A., Yang, R., Henzler, C., Li, Y., Lopez-Campos, F., Castro, E., Toivanen, R., Azad, A., Bolton, D., Goad, J., Grummet, J., Harewood, L., Kourambas, J., Lawrentschuk, N., Moon, D., Murphy, D. G., Sengupta, S., Snow, R., Thorne, H., Mitchell, C., Pedersen, J., Clouston, D., Norden, S., Ryan, A., Dehm, S. M., Tilley, W. D., Pearson, R. B., Hannan, R. D., Frydenberg, M., Furic, L., Taylor, R. A. & Risbridger, G. P., 1 Nov 2018, In : European Urology. 74, 5, p. 562-572 11 p.

Research output: Contribution to journal › Article › Research › peer-review

Prevalence of systemic anticancer therapy for patients within the last 30 days of life: experience in a private hospital oncology group

Wein, L., Rowe, C., Brady, B., Handolias, D., Lipton, G. L., Pook, D., Stanley, R. & Haines, I., 1 Mar 2017, In : Internal Medicine Journal. 47, 3, p. 280-283 4 p.

Research output: Contribution to journal › Article › Research › peer-review

Establishment of primary patient-derived xenografts of palliative TURP specimens to study castrate-resistant prostate cancer

Lawrence, M. G., Pook, D. W., Wang, H., Porter, L. H., Frydenberg, M., Kourambas, J., Appu, S., Poole, C., Beardsley, E. K., Ryan, A. J., Norden, S., Papargiris, M., Risbridger, G. P. & Taylor, R. A., 2015, In : Prostate. 75, 13, p. 1475 - 1483 9 p.

Research output: Contribution to journal › Article › Research › peer-review