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Role of JUN/AP-1 in acute and chronic kidney injury. Mechanisms of acute kidney injury in high risk individuals. Novel roles for macrophages in renal fibrosis.

1992 …2020

Research output per year

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Research Output

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Article

Abnormal p38 mitogen-activated protein kinase signalling in human and experimental diabetic nephropathy

Adhikary, L., Chow, F. YF., Nikolic-Paterson, D. J., Stambe, C., Dowling, J. P., Atkins, R. C. & Tesch, G. H., 2004, In : Diabetologia. 47, 7, p. 1210 - 1222 13 p.

Research output: Contribution to journalArticleResearchpeer-review

135 Citations (Scopus)

Activated macrophages down-regulate podocyte nephrin and podocin expression via stress-activated protein kinases

Ikezumi, Y., Suzuki, T., Karasawa, T., Kawachi, H., Nikolic-Paterson, D. J. & Uchiyama, M., 2008, In : Biochemical and Biophysical Research Communications. 376, 4, p. 706 - 711 6 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

Activation and cellular localization of the p38 and JNK MAPK pathways in rat crescentic glomerulonephritis

Stambe, C., Atkins, R. C., Hill, P. A. & Nikolic-Paterson, D. J., 2003, In : Kidney International. 64, 6, p. 2121 - 2132 12 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)

Activation of the ERK pathway precedes tubular proliferation in the obstructed rat kidney

Masaki, T., Foti, R., Hill, P. A., Ikezumi, Y., Atkins, R. C. & Nikolic-Paterson, D. J., 2003, In : Kidney International. 63, 4, p. 1256 - 1264 9 p.

Research output: Contribution to journalArticleResearchpeer-review

80 Citations (Scopus)

Activation of the extracellular-signal regulated protein kinase pathway in human glomerulopathies

Masaki, T., Stambe, C., Hill, P. A., Dowling, J. P., Atkins, R. C. & Nikolic-Paterson, D. J., 2004, In : Journal of the American Society of Nephrology. 15, 7, p. 1835 - 1843 9 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)

Adhesion molecules in glomerulonephritis

Nikolic-Paterson, D. J., Main, I. W., Lan, H. Y., Hill, P. A. & Atkins, R. C., 1 Jul 1994, In : Springer Seminars in Immunopathology. 16, 1, p. 3-22 20 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Adoptive transfer studies demonstrate that macrophages can induce proteinuria and esangial cell proliferation

Ikezumi, Y., Hurst, L. A., Masaki, T., Atkins, R. C. & Nikolic-Paterson, D. J., 2003, In : Kidney International. 63, 1, p. 83 - 95 13 p.

Research output: Contribution to journalArticleResearchpeer-review

120 Citations (Scopus)

Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products(RAGE)

Oldfield, M. D., Bach, L. A., Forbes, J. M., Nikolic-Paterson, D. J., McRobert, A., Thallas, V., Atkins, R. C., Osicka, T., Jerums, G. & Cooper, M. E., 2001, In : Journal of Clinical Investigation. 108, 12, p. 1853 - 1863 11 p.

Research output: Contribution to journalArticleResearchpeer-review

345 Citations (Scopus)

A functional role for osteopontin in experimental crescentic glomerulonephritis in the rat

Yu, X. Q., Nikolic-Paterson, D. J., Mu, W., Giachelli, C. M., Atkins, R. C., Johnson, R. J. & Lan, H. Y., 6 Feb 1998, In : Proceedings of the Association of American Physicians. 110, 1, p. 50-64 15 p.

Research output: Contribution to journalArticleResearchpeer-review

83 Citations (Scopus)
28 Citations (Scopus)

Alternatively activated macrophages in the pathogenesis of chronic kidney allograft injury

Ikezumi, Y., Suzuki, T., Yamada, T., Hasegawa, H., Kaneko, U., Hara, M., Yanagihara, T., Nikolic-Paterson, D. J. & Saitoh, A., 2015, In : Pediatric Nephrology. 30, 6, p. 1007 - 1017 11 p.

Research output: Contribution to journalArticleResearchpeer-review

40 Citations (Scopus)

A model of acute antibody-mediated renal allograft rejection in the sensitized rat

Chandran, S. R., Mulley, W. R., Kanellis, J., Nikolic-Paterson, D. J. & Ma, F. Y., 1 Jun 2018, In : Experimental and Clinical Transplantation. 16, 3, p. 294-300 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Angiotensin II induces thrombospondin-1 production in human mesangial cells via p38 MAPK and JNK: A mechanism for activation of latent TGF-β 1

Naito, T., Masaki, T., Nikolic-Paterson, D. J., Tanji, C., Yorioka, N. & Kohno, N., 1 Feb 2004, In : American Journal of Physiology-Renal Physiology. 286, 2 55-2, p. F278-F287

Research output: Contribution to journalArticleResearchpeer-review

117 Citations (Scopus)

Angiotensin II induces thrombospondin-1 production in human mesangial cells via p38 MAPK and JNK: a mechanism for activation of latent TGF-1

Naito, T., Masaki, T., Nikolic-Paterson, D. J., Tanji, C., Yorioka, N. & Kohno, N., 2004, In : American Journal of Physiology-Renal Physiology. 286, p. 278 - 287 10 p.

Research output: Contribution to journalArticleResearchpeer-review

An inhibitor of spleen tyrosine kinase suppresses experimental crescentic glomerulonephritis

Han, Y., Ma, F. Y., Di Paolo, J. & Nikolic-Paterson, D. J., 1 Jan 2018, In : International Journal of Immunopathology and Pharmacology. 32, 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2 Citations (Scopus)

A pathogenic role for c-Jun amino-terminal kinase signaling in renal fibrosis and tubular cell apoptosis

Ma, F., Flanc, R., Tesch, G. H., Han, Y., Atkins, R. C., Bennett, B. L., Friedman, G. C., Fan, J-H. & Nikolic-Paterson, D. J., 2007, In : Journal of the American Society of Nephrology. 18, 2, p. 472 - 484 13 p.

Research output: Contribution to journalArticleResearchpeer-review

106 Citations (Scopus)

A pathogenic role for JNK signaling in experimental anti-GBM glomerulonephritis

Flanc, R., Ma, F., Tesch, G. H., Han, Y., Atkins, R. C., Bennett, B. L., Friedman, G. C., Fan, J-H. & Nikolic-Paterson, D. J., 2007, In : Kidney International. 72, 6, p. 698 - 708 11 p.

Research output: Contribution to journalArticleResearchpeer-review

49 Citations (Scopus)

A role for spleen tyrosine kinase in renal fibrosis in the mouse obstructed kidney

Ma, F. Y., Blease, K. & Nikolic-Paterson, D. J., 1 Feb 2016, In : Life Sciences. 146, p. 192-200 9 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

A Sensitive Method of Non-Radioactive In Situ Hybridization for mRNA Localization within Human Renal Biopsy Specimens: Use of Digoxigenin Labeled Oligonucleotides

Miyazaki, M., Endoh, M., Nomoto, Y., Sakai, H., Nikolic-Paterson, D. J., Atkins, R. C. & Koji, T., 1 Jan 1994, In : Internal Medicine. 33, 2, p. 87-91 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
23 Citations (Scopus)
Open Access
87 Citations (Scopus)
55 Citations (Scopus)

ASK1 contributes to fibrosis and dysfunction in models of kidney disease

Liles, J. T., Corkey, B. K., Notte, G. T., Budas, G. R., Lansdon, E. B., Hinojosa-Kirschenbaum, F., Badal, S. S., Lee, M., Schultz, B. E., Wise, S., Pendem, S., Graupe, M., Castonguay, L., Koch, K. A., Wong, M. H., Papalia, G. A., French, D. M., Sullivan, T., Huntzicker, E. G., Ma, F. Y. & 5 others, Nikolic-Paterson, D. J., Altuhaifi, T., Yang, H., Fogo, A. B. & Breckenridge, D. G., 1 Oct 2018, In : Journal of Clinical Investigation. 128, 10, p. 4485-4500 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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24 Citations (Scopus)

ASK1 inhibitor halts progression of diabetic nephropathy in Nos3-deficient mice

Tesch, G. H., Ma, F., Han, Y., Liles, J. T., Breckenridge, D. G. & Nikolic-Paterson, D. J., 2015, In : Diabetes. 64, 11, p. 3903 - 3913 11 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

ASK1 inhibitor treatment suppresses p38/JNK signalling with reduced kidney inflammation and fibrosis in rat crescentic glomerulonephritis

Amos, L. A., Ma, F. Y., Tesch, G. H., Liles, J. T., Breckenridge, D. G., Nikolic-Paterson, D. J. & Han, Y., 1 Sep 2018, In : Journal of Cellular and Molecular Medicine. 22, 9, p. 4522-4533 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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11 Citations (Scopus)

A small-molecule macrophage migration inhibitory factor antagonist protects against glomerulonephritis in lupus-prone NZB/NZW F1 and MRL/lpr mice

Leng, L., Chen, L., Fan, J., Greven, D., Arjona, A., Du, X., Austin, D., Kashgarian, M., Yin, Z., Huang, X., Lan, H. Y., Lolis, E., Nikolic-Paterson, D. & Bucala, R., 2011, In : Journal of Immunology. 186, 1, p. 527 - 538 12 p.

Research output: Contribution to journalArticleResearchpeer-review

90 Citations (Scopus)

Blockade of p38 MAPK ameliorates acute inflammatory renal injury in rat anti-GBM glomerulonephritis

Stambe, C., Atkins, R. C., Tesch, G. H., Kapoun, A. M., Hill, P. A., Schreiner, G. F. & Nikolic-Paterson, D. J., 2003, In : Journal of the American Society of Nephrology. 14, p. 338 - 351 14 p.

Research output: Contribution to journalArticleResearchpeer-review

92 Citations (Scopus)

CD4+ T cells: a potential player in renal fibrosis.

Nikolic-Paterson, D. J., 2010, In : Kidney International. 78, 4, p. 333 - 335 3 p.

Research output: Contribution to journalArticleOther

18 Citations (Scopus)

CD44 and hyaluronan expression in the development of experimental crescentic glomerulonephritis

Jun, Z., Hill, P. A., Lan, H. Y., Foti, R., Mu, W., Atkins, R. C. & Nikolic-Paterson, D. J., 1 Jan 1997, In : Clinical and Experimental Immunology. 108, 1, p. 69-77 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
48 Citations (Scopus)

CD44-mediated neutrophil apoptosis in the rat

Takazoe, K., Tesch, G. H., Hill, P. A., Hurst, L. A., Jun, Z., Lan, H. Y., Atkins, R. C. & Nikolic-Paterson, D. J., 2000, In : Kidney International. p. 1920 - 1930 11 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

c-fms blockade reverses glomerular macrophage infiltration and halts development of crescentic anti-GBM glomerulonephritis in the rat

Han, Y., Ma, F., Tesch, G., Manthey, C. & Nikolic-Paterson, D., 2011, In : Laboratory Investigation. 91, 7, p. 978 - 991 14 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Characteristics of albumin processing during renal passage in anti-thy1 and anti-glomerular basement membrane glomerulonephritis

Eppel, G. A., Takazoe, K., Nikolic-Paterson, D. J., Lan, H. Y., Atkins, R. C. & Comper, W. D., 2000, In : American Journal of Kidney Diseases. p. 418 - 426 9 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Characterization of the urinary albumin degradation pathway in the isolated perfused rat kidney

Hilliard, L. M., Osicka, T. M., Clavant, S. P., Robinson, P. J., Nikolic-Paterson, D. J. & Comper, W. D., 2006, In : Journal of Laboratory and Clinical Medicine. 147, 1, p. 36 - 44 9 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Chloride channel ClC-5 binds to aspartyl aminopeptidase to regulate renal albumin endocytosis

Lee, A., Slattery, C., Nikolic-Paterson, D. J., Hryciw, D. H., Wilk, S., Wilk, E., Zhang, Y., Valova, V. A., Robinson, P. J., Kelly, D. J. & Poronnik, P., 2015, In : American Journal of Physiology-Renal Physiology. 308, 7, p. 784 - 792 9 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

c-Jun amino terminal kinase 1 deficient mice are protected from streptozotocin-induced islet injury

Fukuda, K., Tesch, G. H. & Nikolic-Paterson, D. J., 2008, In : Biochemical and Biophysical Research Communications. 366, 3, p. 710 - 716 7 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Combined Blockade of Smad3 and JNK Pathways Ameliorates Progressive Fibrosis in Folic Acid Nephropathy

Jiang, M., Fan, J., Qu, X., Li, S., Nilsson, S. K., Sun, Y. B. Y., Chen, Y., Yu, D., Liu, D., Liu, B-C., Tang, M., Chen, W., Ren, Y., Nikolic-Paterson, D. J., Jiang, X., Li, J. & Yu, X., 9 Aug 2019, In : Frontiers in Pharmacology. 10, 17 p., 880.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Combined inhibition of CCR2 and ACE provides added protection against progression of diabetic nephropathy in Nos3-deficient mice

Tesch, G. H., Pullen, N., Jesson, M. I., Schlerman, F. J. & Nikolic-Paterson, D. J., 1 Dec 2019, In : American Journal of Physiology-Renal Physiology. 317, 6, p. F1439-F1449 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Combined interleukin 1 and tumour necrosis factor a blockade in rat crescentic anti-glomerular basement membrane glomerulonephritis

Lan, H. Y., Song, Q., Nikolic-Paterson, D. J., Tesch, G. H., Mu, W. & Atkins, R. C., 1 Jan 2001, In : Nephrology. 6, 5, p. 214-220 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Contrasting effects of steroids and mizoribine on macrophage activation and glomerular lesions in rat Thy-1 mesangial proliferative glomerulonephritis

Ikezumi, Y., Suzuki, T., Karasawa, T., Hasegawa, H., Kawachi, H., Nikolic-Paterson, D. J. & Uchiyama, M., 2010, In : American Journal of Nephrology. 31, 3, p. 273 - 282 10 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Cyclophilin a promotes inflammation in acute kidney injury but not in renal fibrosis

Leong, K. G., Ozols, E., Kanellis, J., Nikolic-Paterson, D. J. & Ma, F. Y., 2 May 2020, In : International Journal of Molecular Sciences. 21, 10, 13 p., 3667.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Cyclophilin D promotes tubular cell damage and the development of interstitial fibrosis in the obstructed kidney

Hou, W., Leong, K. G., Ozols, E., Tesch, G. H., Nikolic-Paterson, D. J. & Ma, F. Y., 1 Mar 2018, In : Clinical and Experimental Pharmacology and Physiology. 45, 3, p. 250-260 11 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Cytokine profiles in the testes of rats treated with lipopolysaccharide reveal localized suppression of inflammatory responses

O'Bryan, M. K., Gerdprasert, O., Nikolic-Paterson, D. J., Meinhardt, A., Muir, J. A., Foulds, L. M., Phillips, D. J., de Kretser, D. M. & Hedger, M. P., 2005, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 288, 6, p. R1744 - R1755 12 p.

Research output: Contribution to journalArticleResearchpeer-review

61 Citations (Scopus)

Cytokine regulation of mesangial cells

Kakizaki, Y., Ootaka, T., Nikolic-Paterson, D. J., Miyazaki, M. & Atkins, R. C., 1 Jan 1993, In : Blood Purification. 11, 1, p. 54-55 2 p.

Research output: Contribution to journalArticleOtherpeer-review

Delayed-type hypersensitivity mediates Bowman's capsule rupture in Tamm-Horsfall protein-induced tubulointerstitial nephritis in the rat

Song, Q., Nikolic-Paterson, D. J., Atkins, R. C., Bacher, M., Bucala, R. & Lan, H. Y., 1 Jan 1996, In : Nephrology. 2, 6, p. 417-427 11 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes

Tesch, G. H., Sourris, K., Summers, S. A., McCarthy, D., Ward, M. S., Borg, D. J., Gallo, L. A., Fotheringham, A. K., Pettit, A. R., Yap, F. Y. T., Harcourt, B. E., Tan, A. L. Y., Kausman, J. Y., Nikolic-Paterson, D. J., Kitching, A. R. & Forbes, J. M., 2014, In : Diabetologia. 57, 9, p. 1977 - 1985 9 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

De Novo CD44 Expression by Proliferating Mesangial Cells in Rat Anti-Thy-1 Nephritis

Nikolic-Paterson, D. J., Jun, Z., Tesch, G. H., Lan, H. Y., Foti, R. & Atkins, R. C., 1 Jul 1996, In : Journal of the American Society of Nephrology. 7, 7, p. 1006-1014 9 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

De novo glomerular osteopontin expression in rat crescentic glomerulonephritis

Lan, H. Y., Yu, X. Q., Yang, N., Nikolic-Paterson, D. J., Mu, W., Pichler, R., Johnson, R. J. & Atkins, R. C., 1 Jan 1998, In : Kidney International. 53, 1, p. 136-145 10 p.

Research output: Contribution to journalArticleResearchpeer-review

72 Citations (Scopus)

De novo renal expression of macrophage migration inhibitory factor during the development of rat crescentic glomerulonephritis

Lan, H. Y., Mu, W., Yang, N., Meinhardt, A., Nikolic-Paterson, D. J., Ng, Y. Y., Bacher, M., Atkins, R. C. & Bucala, R., 1 Jan 1996, In : American Journal of Pathology. 149, 4, p. 1119-1127 9 p.

Research output: Contribution to journalArticleResearchpeer-review

106 Citations (Scopus)

Deoxyspergualin inhibits mesangial cell proliferation and major histocompatibility complex class II expression

Nikolic-Paterson, D. J., Tesch, G. H., Lan, H. Y., Foti, R. & Atkins, R. C., 1 Jan 1995, In : Journal of the American Society of Nephrology. 5, 11, p. 1895-1902 8 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Deoxyspergualin suppresses local macrophage proliferation in rat renal allograft rejection

Kerr, P. G., Nikolic-Paterson, D. J., Lan, H. Y., Tesch, G., Rainone, S. & Atkins, R. C., 15 Sep 1994, In : Transplantation. 58, 5, p. 596-601 6 p.

Research output: Contribution to journalArticleResearchpeer-review

54 Citations (Scopus)