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Role of JUN/AP-1 in acute and chronic kidney injury. Mechanisms of acute kidney injury in high risk individuals. Novel roles for macrophages in renal fibrosis.

1992 …2020

Research output per year

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Research Output

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Article
1998

A functional role for osteopontin in experimental crescentic glomerulonephritis in the rat

Yu, X. Q., Nikolic-Paterson, D. J., Mu, W., Giachelli, C. M., Atkins, R. C., Johnson, R. J. & Lan, H. Y., 6 Feb 1998, In : Proceedings of the Association of American Physicians. 110, 1, p. 50-64 15 p.

Research output: Contribution to journalArticleResearchpeer-review

83 Citations (Scopus)

De novo glomerular osteopontin expression in rat crescentic glomerulonephritis

Lan, H. Y., Yu, X. Q., Yang, N., Nikolic-Paterson, D. J., Mu, W., Pichler, R., Johnson, R. J. & Atkins, R. C., 1 Jan 1998, In : Kidney International. 53, 1, p. 136-145 10 p.

Research output: Contribution to journalArticleResearchpeer-review

72 Citations (Scopus)

Immunoregulatory activity in adult rat testicular interstitial fluid: Roles of interleukin-1 and transforming growth factor β

Hedger, M. P., Nikolic-Paterson, D. J., Hutchinson, P., Atkins, R. C. & De Kretser, D. M., Apr 1998, In : Biology of Reproduction. 58, 4, p. 927-934 8 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Interleukin-10 differentially modulates MHC class II expression by mesangial cells and macrophages in vitro and in vivo

Chadban, S. J., Tesch, G. H., Foti, R., Lan, H. Y., Atkins, R. C. & Nikolic-Paterson, D. J., 16 Sep 1998, In : Immunology. 94, 1, p. 72-78 7 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Local macrophage and myofibroblast proliferation in progressive renal injury in the rat remnant kidney

Yang, N., Wu, L. L., Nikolic-Paterson, D. J., Ng, Y. Y., Yang, W. C., Mu, W., Gilbert, R. E., Cooper, M. E., Atkins, R. C. & Lan, H. Y., 1 Aug 1998, In : Nephrology Dialysis Transplantation. 13, 8, p. 1967-1974 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
84 Citations (Scopus)

Local macrophage proliferation in human glomerulonephritis

Yang, N., Isbel, N. M., Nikolic-Paterson, D. J., Li, Y., Ye, R., Atkins, R. C. & Lan, H. Y., 1 Jan 1998, In : Kidney International. 54, 1, p. 143-151 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
127 Citations (Scopus)

Macrophage migration inhibitory factor expression in human renal allograft rejection

Lan, H. Y., Yang, N., Brown, F. G., Isbel, N. M., Nikolic-Paterson, D. J., Mu, W., Metz, C. N., Bacher, M., Atkins, R. C. & Bucala, R., 15 Dec 1998, In : Transplantation. 66, 11, p. 1465-1471 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
85 Citations (Scopus)

Rat mesangial cells express macrophage migration inhibitory factor in vitro and in vivo

Tesch, G. H., Nikolic-Paterson, D. J., Metz, C. N., Mu, W., Bacher, M., Bucala, R., Atkins, R. C. & Lan, H. Y., 1 Mar 1998, In : Journal of the American Society of Nephrology. 9, 3, p. 417-424 8 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

Reversal of established rat crescentic glomerulonephritis by blockade of macrophage migration inhibitory factor (MIF): Potential role of MIF in regulating glucocorticoid production

Yang, N., Nikolic-Paterson, D. J., Ng, Y. Y., Mu, W., Metz, C., Bacher, M., Meinhardt, A., Bucala, R., Atkins, R. C. & Lan, H. Y., 1 Sep 1998, In : Molecular Medicine. 4, 6, p. 413-424 12 p.

Research output: Contribution to journalArticleResearchpeer-review

76 Citations (Scopus)

Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats

Ng, Y. Y., Huang, T. P., Yang, W. C., Chen, Z-P., Yang, A. H., Mu, W., Nikolic- Paterson, D. J., Atkins, R. C. & Lan, H. Y., 1 Jan 1998, In : Kidney International. 54, 3, p. 864-876 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
331 Citations (Scopus)
1999

Glomerular epithelial-myofibroblast transdifferentiation in the evolution of glomerular crescent formation

Ng, Y. Y., Fan, J. M., Mu, W., Nikolic-Paterson, D. J., Yang, W. C., Huang, T. P., Atkins, R. C. & Lan, H. Y., 1 Jan 1999, In : Nephrology Dialysis Transplantation. 14, 12, p. 2860-2872 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
89 Citations (Scopus)

IL-1 up-regulates osteopontin expression in experimental crescentic glomerulonephritis in the rat

Yu, X. Q., Fan, J. M., Nikolic-Paterson, D. J., Yang, N., Mu, W., Pichler, R., Johnson, R. J., Atkins, R. C. & Lan, H. Y., 1 Jan 1999, In : American Journal of Pathology. 154, 3, p. 833-841 9 p.

Research output: Contribution to journalArticleResearchpeer-review

80 Citations (Scopus)

Mechanisms of glomerular macrophage infiltration in lipid-induced renal injury

Hattori, M., Nikolic-Paterson, D. J., Miyazaki, K., Isbel, N. M., Lan, H. Y., Atkins, R. C., Kawaguchi, H. & Ito, K., 1 Dec 1999, In : Kidney International. 56, 71, p. S47-S50 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
54 Citations (Scopus)

Transforming growth factor-β regulates tubular epithelial-myofibroblast transdifferentiation in vitro

Fan, J. M., Yee-Yung, N. G., Hill, P. A., Nikolic-Paterson, D. J., Mu, W., Atkins, R. C. & Lan, H. Y., 1 Jan 1999, In : Kidney International. 56, 4, p. 1455-1467 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
449 Citations (Scopus)

Up-regulation of macrophage migration inhibitory factor in acute renal allograft rejection in the rat

Brown, F. G., Nikolic-Paterson, D. J., Metz, C., Bucala, R., Atkins, R. C. & Lan, H. Y., 17 Nov 1999, In : Clinical and Experimental Immunology. 118, 2, p. 329-336 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
37 Citations (Scopus)
2000

CD44-mediated neutrophil apoptosis in the rat

Takazoe, K., Tesch, G. H., Hill, P. A., Hurst, L. A., Jun, Z., Lan, H. Y., Atkins, R. C. & Nikolic-Paterson, D. J., 2000, In : Kidney International. p. 1920 - 1930 11 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Characteristics of albumin processing during renal passage in anti-thy1 and anti-glomerular basement membrane glomerulonephritis

Eppel, G. A., Takazoe, K., Nikolic-Paterson, D. J., Lan, H. Y., Atkins, R. C. & Comper, W. D., 2000, In : American Journal of Kidney Diseases. p. 418 - 426 9 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Expression of macrophage migration inhibitory factor in human glomerulonephritis

Lan, H. Y., Yang, N., Nikolic-Paterson, D. J., Yu, X. Q., Mu, W., Isbel, N. M., Metz, C. N., Bucala, R. & Atkins, R. C., 1 Jan 2000, In : Kidney International. 57, 2, p. 499-509 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
145 Citations (Scopus)

In vivo administration of a nuclear transcription factor-κB decoy suppresses experimental crescentic glomerulonephritis

Tomita, N., Morishita, R., Lan, H. Y., Yamamoto, K., Hashizume, M., Notake, M., Toyosawa, K., Fujitani, B., Mu, W., Nikolic-Paterson, D. J., Atkins, R. C., Kaneda, Y., Higaki, J. & Ogihara, T., 1 Jul 2000, In : Journal of the American Society of Nephrology. 11, 7, p. 1244-1252 9 p.

Research output: Contribution to journalArticleResearchpeer-review

102 Citations (Scopus)

Up-regulation of the tumour-associated marker CD44V6 in experimental kidney disease

Takazoe, K., Foti, R., Tesch, G. H., Hurst, L. A., Lan, H. Y., Atkins, R. C. & Nikolic-Paterson, D. J., 2000, In : Clinical and Experimental Immunology. p. 523 - 532 10 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)
2001

Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products(RAGE)

Oldfield, M. D., Bach, L. A., Forbes, J. M., Nikolic-Paterson, D. J., McRobert, A., Thallas, V., Atkins, R. C., Osicka, T., Jerums, G. & Cooper, M. E., 2001, In : Journal of Clinical Investigation. 108, 12, p. 1853 - 1863 11 p.

Research output: Contribution to journalArticleResearchpeer-review

346 Citations (Scopus)

Combined interleukin 1 and tumour necrosis factor a blockade in rat crescentic anti-glomerular basement membrane glomerulonephritis

Lan, H. Y., Song, Q., Nikolic-Paterson, D. J., Tesch, G. H., Mu, W. & Atkins, R. C., 1 Jan 2001, In : Nephrology. 6, 5, p. 214-220 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Glomerular permselectivity factors are not responsible for the increase in fractional clearance of albumin in rat glomerulonephritis

Greive, K. A., Nikolic-Paterson, D. J., Guimaraes, M. A. M., Nikolovski, J., Pratt, L. M., Mu, W., Atkins, R. C. & Comper, W. D., 2001, In : American Journal of Pathology. 159, 3, p. 1159 - 1170 12 p.

Research output: Contribution to journalArticleResearchpeer-review

60 Citations (Scopus)

Interleukin-1 induces tubular epithelial-myofibroblast transdifferentiation through a transforming growth factor-β1-dependent mechanism in vitro

Fan, J. M., Huang, X. R., Ng, Y. Y., Nikolic-Paterson, D. J., Mu, W., Atkins, R. C. & Lan, H. Y., 1 Jan 2001, In : American Journal of Kidney Diseases. 37, 4, p. 820-831 12 p.

Research output: Contribution to journalArticleResearchpeer-review

134 Citations (Scopus)

LF15-0195 prevents the induction and inhibits the progression of rat anti-GBM disease

Tesch, G. H., Hill, P. A., Wei, M., Nikolic-Paterson, D. J., Dutartre, P. & Atkins, R. C., 2001, In : Kidney International. 60, 4, p. 1354 - 1365 12 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Local macrophage proliferation correlates with increased renal M-CSF expression in human glomerulonephritis

Isbel, N. M., Nikolic-Paterson, D. J., Hill, P. A., Dowling, J. & Atkins, R. C., 1 Jan 2001, In : Nephrology Dialysis Transplantation. 16, 8, p. 1638-1647 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
67 Citations (Scopus)

PDGF signal transduction inhibition ameliorates experimental mesangial proliferative glomerulonephritis

Gilbert, R. E., Kelly, D. J., McKay, T., Chadban, S., Hill, P. A., Cooper, M. E., Atkins, R. C. & Nikolic-Paterson, D. J., 1 Jan 2001, In : Kidney International. 59, 4, p. 1324-1332 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
118 Citations (Scopus)

T-cell-specific therapy in autoimmune glomerulonephritis.

Nikolic-Paterson, D. J., 1 Jan 2001, In : American Journal of Kidney Diseases. 38, 6, p. 1321-1324 4 p.

Research output: Contribution to journalArticleOtherpeer-review

3 Citations (Scopus)

The role of macrophages in glomerulonephritis

Nikolic-Paterson, D. J. & Atkins, R. C., 27 Aug 2001, In : Nephrology Dialysis Transplantation. 16, SUPPL. 5, p. 3-7 5 p.

Research output: Contribution to journalArticleResearchpeer-review

124 Citations (Scopus)

Tubular phenotypic change in progressive tubulointerstitial fibrosis in human glomerulonephritis

Jinde, K., Nikolic-Paterson, D. J., Huang, X. R., Sakai, H., Kurokawa, K., Atkins, R. C. & Lan, H. Y., 1 Jan 2001, In : American Journal of Kidney Diseases. 38, 4, p. 761-769 9 p.

Research output: Contribution to journalArticleResearchpeer-review

125 Citations (Scopus)

Tubules are the major site of M-CSF production in experimental kidney disease: Correlation with local macrophage proliferation

Isbel, N. M., Hill, P. A., Foti, R., Mu, W., Hurst, L. A., Stambe, C., Lan, H. Y., Atkins, R. C. & Nikolic-Paterson, D. J., 1 Jan 2001, In : Kidney International. 60, 2, p. 614-625 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
63 Citations (Scopus)

Urine macrophage migration inhibitory factor concentrations as a diagnostic tool in human renal allograft rejection

Brown, F. G., Nikolic-Paterson, D. J., Chadban, S. J., Dowling, J., Jose, M., Metz, C. N., Bucala, R. & Atkins, R. C., 27 Jun 2001, In : Transplantation. 71, 12, p. 1777-1783 7 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

Urine macrophage migration inhibitory factor reflects the severity of renal injury in human glomerulonephritis

Brown, F. G., Nikolic-Paterson, D. J., Hill, P. A., Isbel, N. M., Dowling, J., Metz, C. M. & Atkins, R. C., 1 Dec 2001, In : Journal of the American Society of Nephrology. 13, SUPPL. 1, p. 7 - 13 7 p.

Research output: Contribution to journalArticleResearchpeer-review

61 Citations (Scopus)

Variable toxicity of dyes used in micropuncture studies

Nikolic-Paterson, D. J., Hurst, L. A. & Comper, W. D., 2001, In : Nephrology. 6, 1, p. 221 - 222 2 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)
2002

Expression of monocyte chemoattractant protein-1 and macrophage colony-stimulating factor in normal and inflamed rat testis

Gerdprasert, O., O'Bryan, M. K., Nikolic-Paterson, D. J., Sebire, K. L., de Kretser, D. M. & Hedger, M. P., 2002, In : Molecular Human Reproduction. 8, 6, p. 518 - 524 7 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

IL-10 induces mesangial cell proliferation via a PDGF-dependent mechanism

Robertson, T. E., Nikolic-Paterson, D. J., Hurst, L. A., Atkins, R. C. & Chadban, S. J., 2002, In : Clinical and Experimental Immunology. 130, 2, p. 241 - 244 4 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Interleukin 1 induces renal CD44 expression in vivo and in vitro: Role of the transcription factor Egr-1

Takazoe, K., Foti, R., Hurst, L. A., Lan, H. Y., Atkins, R. C. & Nikolic-Paterson, D. J., 23 Sep 2002, In : Nephrology. 7, 3, p. 136-144 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Long-term anti-glomerular basement membrane disease in the rat: A model of chronic glomerulonephritis with nephrosis, hypertension and progressive renal failure

Fu, P., Robertson, T., Hill, P., Tesch, G., Nikolic-Paterson, D. J., Atkins, R. C. & Chadban, S. J., 23 Sep 2002, In : Nephrology. 7, 3, p. 145-154 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Macrophage accumulation at a site of renal inflammation is dependent on the M-CSF/c-fms pathway

Le Meur, Y., Tesch, G. H., Hill, P. A., Mu, W., Foti, R., Nikolic-Paterson, D. J. & Atkins, R., 2002, In : Journal of leukocyte biology. 72, 3, p. 530 - 537 8 p.

Research output: Contribution to journalArticleResearchpeer-review

68 Citations (Scopus)
2003

Activation and cellular localization of the p38 and JNK MAPK pathways in rat crescentic glomerulonephritis

Stambe, C., Atkins, R. C., Hill, P. A. & Nikolic-Paterson, D. J., 2003, In : Kidney International. 64, 6, p. 2121 - 2132 12 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)

Activation of the ERK pathway precedes tubular proliferation in the obstructed rat kidney

Masaki, T., Foti, R., Hill, P. A., Ikezumi, Y., Atkins, R. C. & Nikolic-Paterson, D. J., 2003, In : Kidney International. 63, 4, p. 1256 - 1264 9 p.

Research output: Contribution to journalArticleResearchpeer-review

80 Citations (Scopus)

Adoptive transfer studies demonstrate that macrophages can induce proteinuria and esangial cell proliferation

Ikezumi, Y., Hurst, L. A., Masaki, T., Atkins, R. C. & Nikolic-Paterson, D. J., 2003, In : Kidney International. 63, 1, p. 83 - 95 13 p.

Research output: Contribution to journalArticleResearchpeer-review

120 Citations (Scopus)

Blockade of p38 MAPK ameliorates acute inflammatory renal injury in rat anti-GBM glomerulonephritis

Stambe, C., Atkins, R. C., Tesch, G. H., Kapoun, A. M., Hill, P. A., Schreiner, G. F. & Nikolic-Paterson, D. J., 2003, In : Journal of the American Society of Nephrology. 14, p. 338 - 351 14 p.

Research output: Contribution to journalArticleResearchpeer-review

92 Citations (Scopus)

Heterogeneity of antigen expression explains controversy over glomerular macrophage accumulation in mouse glomerulonephritis

Masaki, T., Chow, F. YF., Nikolic-Paterson, D. J., Atkins, R. C. & Tesch, G. H., 2003, In : Nephrology Dialysis Transplantation. 18, 1, p. 178 - 181 4 p.

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)

Induction of MIF synthesis and secretion by tubular epithelial cells - a novel action of angiotensin II

Rice, E. K., Tesch, G. H., Cao, Z., Cooper, M. E., Metz, C. N., Bucala, R., Atkins, R. C. & Nikolic-Paterson, D. J., 2003, In : Kidney International. 63, 4, p. 1265 - 1275 11 p.

Research output: Contribution to journalArticleResearchpeer-review

48 Citations (Scopus)

Interferon-gamma augments acute macrophage-mediated renal injury via a glucocorticoid-sensitive mechanism

Ikezumi, Y., Atkins, R. C. & Nikolic-Paterson, D. J., 2003, In : Journal of the American Society of Nephrology. 14, 4, p. 888 - 898 11 p.

Research output: Contribution to journalArticleResearchpeer-review

58 Citations (Scopus)

Interferon-gamma induces macrophage migration inhibitory factor synthesis and secretion by tubular epithelial cells

Rice, E. K., Nikolic-Paterson, D. J., Hill, P. A., Metz, C. N., Bucala, R., Atkins, R. C. & Tesch, G. H., 2003, In : Nephrology. 8, 3, p. 156 - 161 6 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Role of interleukin-10 in rat mesangioproliferative glomerulonephritis

Robertson, T. E., Nikolic-Paterson, D. J., Tesch, G. H., Foti, R., Atkins, R. C. & Chadban, S. J., 2003, In : Nephrology. 8, 1, p. 33 - 41 9 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)
2004

Abnormal p38 mitogen-activated protein kinase signalling in human and experimental diabetic nephropathy

Adhikary, L., Chow, F. YF., Nikolic-Paterson, D. J., Stambe, C., Dowling, J. P., Atkins, R. C. & Tesch, G. H., 2004, In : Diabetologia. 47, 7, p. 1210 - 1222 13 p.

Research output: Contribution to journalArticleResearchpeer-review

137 Citations (Scopus)