1998 …2024
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Research Output 1998 2019

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2019
2 Citations (Scopus)

Comparison of Magnetic Resonance Analysis of Myocardial Scarring With Biomarker Release Following S-T Elevation Myocardial Infarction

Costello, B. T., Stub, D., Hare, J., Ellims, A. H., Wang, X., Smith, K., Bernard, S., Nehme, Z., Stephenson, M., Bray, J. E., Cameron, P., Barger, B., Meredith, I. T., Kaye, D. M., Iles, L., Taylor, A. J. & on behalf of the AVOID Investigators, Mar 2019, In : Heart Lung and Circulation. 28, 3, p. 397-405 9 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

The gut microbiota and blood pressure in experimental models

Jama, H. A., Kaye, D. M. & Marques, F. Z., 1 Mar 2019, In : Current Opinion in Nephrology and Hypertension. 28, 2, p. 97-104 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

Age-related differential structural and transcriptomic responses in the hypertensive heart

Marques, F. Z., Chu, P. Y., Ziemann, M., Kaspi, A., Kiriazis, H., Du, X. J., El-Osta, A. & Kaye, D. M., 9 Jul 2018, In : Frontiers in Physiology. 9, JUL, 13 p., 817.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

Characterising risk of in-hospital mortality following cardiac arrest using machine learning: A retrospective international registry study

Nanayakkara, S., Fogarty, S., Tremeer, M., Ross, K., Richards, B., Bergmeir, C., Xu, S., Stub, D., Smith, K., Tacey, M., Liew, D., Pilcher, D. & Kaye, D. M., 1 Nov 2018, In : PLoS Medicine. 15, 11, 16 p., e1002709.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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10 Citations (Scopus)

Mechanisms responsible for increased circulating levels of galectin-3 in cardiomyopathy and heart failure

Nguyen, M. N., Su, Y., Vizi, D., Fang, L., Ellims, A. H., Zhao, W. B., Kiriazis, H., Gao, X. M., Sadoshima, J., Taylor, A. J., McMullen, J. R., Dart, A. M., Kaye, D. M. & Du, X. J., 1 Dec 2018, In : Scientific Reports. 8, 1, 12 p., 8213.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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11 Citations (Scopus)

Regression of Diffuse Ventricular Fibrosis Following Restoration of Sinus Rhythm With Catheter Ablation in Patients With Atrial Fibrillation and Systolic Dysfunction: A Substudy of the CAMERA MRI Trial

Prabhu, S., Costello, B. T., Taylor, A. J., Gutman, S. J., Voskoboinik, A., McLellan, A. J. A., Peck, K. Y., Sugumar, H., Iles, L., Pathik, B., Nalliah, C. J., Wong, G. R., Azzopardi, S. M., Lee, G., Mariani, J., Kaye, D. M., Ling, L. H., Kalman, J. M. & Kistler, P. M., 1 Aug 2018, In : JACC: Clinical Electrophysiology. 4, 8, p. 999-1007 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Serelaxin attenuates renal inflammation and fibrosis in a mouse model of dilated cardiomyopathy

Giam, B., Chu, P. Y., Kuruppu, S., Smith, A. I., Horlock, D., Murali, A., Kiriazis, H., Du, X-J., Kaye, D. M. & Rajapakse, N. W., 1 Dec 2018, In : Experimental Physiology. 103, 12, p. 1593-1602 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)
Open Access
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2017
10 Citations (Scopus)

A randomized double-blind trial of an interventional device treatment of functional mitral regurgitation in patients with symptomatic congestive heart failure—Trial design of the REDUCE FMR study

Goldberg, S. L., Meredith, I., Marwick, T., Haluska, B. A., Lipiecki, J., Siminiak, T., Mehta, N., Kaye, D. M. & Sievert, H., 1 Jun 2017, In : American Heart Journal. 188, p. 167-174 8 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
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3 Citations (Scopus)

Cardiac magnetic resonance imaging in suspected blunt cardiac injury: A prospective, pilot, cohort study

Burrell, A. JC., Kaye, D. M., Fitzgerald, M. C., Cooper, D. J., Hare, J. L., Costello, B. & Taylor, A. J., May 2017, In : Injury. 48, 5, p. 1013-1019 7 p.

Research output: Contribution to journalArticleResearchpeer-review

115 Citations (Scopus)

Catheter Ablation Versus Medical Rate Control in Atrial Fibrillation and Systolic Dysfunction: The CAMERA-MRI Study

Prabhu, S., Taylor, A. J., Costello, B. T., Kaye, D. M., McLellan, A. J. A., Voskoboinik, A., Sugumar, H., Lockwood, S. M., Stokes, M. B., Pathik, B., Nalliah, C. J., Wong, G. R., Azzopardi, S. M., Gutman, S. J., Lee, G., Layland, J., Mariani, J. A., Ling, L. H., Kalman, J. M. & Kistler, P. M., 17 Oct 2017, In : Journal of the American College of Cardiology. 70, 16, p. 1949-1961 13 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Exercise hemodynamics as a predictor of myocardial recovery in LVAD patients

Segan, L. A., Nanayakkara, S. S., Leet, A. S., Vizi, D. & Kaye, D. M., 1 Jun 2017, In : ASAIO Journal. 63, 3, p. 342-345 4 p.

Research output: Contribution to journalArticleResearchpeer-review

123 Citations (Scopus)

High Fibre Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in DOCA-Salt Hypertensive Mice

Marques, F. Z., Nelson, E., Chu, P. Y., Horlock, D., Fiedler, A., Ziemann, M., Tan, J. K., Kuruppu, S., Rajapakse, N. W., El-Osta, A., Mackay, C. R. & Kaye, D. M., 7 Mar 2017, In : Circulation. 135, 10, p. 964-977 14 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Insulin replacement limits progression of diabetic cardiomyopathy in the low-dose streptozotocin-induced diabetic rat

Tate, M., Deo, M., Cao, A. H., Hood, S. G., Huynh, K., Kiriazis, H., Du, X-J., Julius, T. L., Figtree, G. A., Dusting, G. J., Kaye, D. M. & Ritchie, R. H., 2017, In : Diabetes and Vascular Disease Research. 14, 5, p. 423-433 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

N-Acetylcysteine Attenuates the Development of Renal Fibrosis in Transgenic Mice with Dilated Cardiomyopathy

Giam, B., Kuruppu, S., Chu, P. Y., Smith, A. I., Marques, F. Z., Fiedler, A., Horlock, D., Kiriazis, H., Du, X-J., Kaye, D. M. & Rajapakse, N. W., 18 Dec 2017, In : Scientific Reports. 7, 1, 12 p., 17718.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling

Furtado, M. B., Wilmanns, J. C., Chandran, A., Perera, J., Hon, O., Biben, C., Willow, T. J., Nim, H. T., Kaur, G., Simonds, S., Wu, Q., Willians, D., Salimova, E., Plachta, N., Denegre, J. M., Murray, S. A., Fatkin, D., Cowley, M., Pearson, J. T., Kaye, D. & 4 others, Ramialison, M., Harvey, R. P., Rosenthal, N. A. & Costa, M. W., 23 Mar 2017, In : JCI Insight. 2, 6, p. e88271 18 p., e88271.

Research output: Contribution to journalArticleResearch

24 Citations (Scopus)

Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice

Qin, C. X., May, L. T., Li, R., Cao, N., Rosli, S., Deo, M., Alexander, A. E., Horlock, D., Bourke, J. E., Yang, Y. H., Stewart, A. G., Kaye, D. M., Du, X. J., Sexton, P. M., Christopoulos, A., Gao, X. M. & Ritchie, R. H., 7 Feb 2017, In : Nature Communications. 8, 13 p., 14232.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)

Understanding the Role of the LA in Functional Responses to Heart Failure*

Marwick, T. H. & Kaye, D., Oct 2017, In : JACC: Cardiovascular Imaging. 10, 10, p. 1265-1267 3 p.

Research output: Contribution to journalArticleOtherpeer-review

2016
16 Citations (Scopus)

Acute kidney injury following peripheral angiography and endovascular therapy: A systematic review of the literature

Prasad, A., Ortiz-Lopez, C., Khan, A., Levin, D. & Kaye, D. M., 1 Aug 2016, In : Catheterization and Cardiovascular Interventions. 88, 2, p. 264-273 10 p.

Research output: Contribution to journalArticleResearchpeer-review

84 Citations (Scopus)

A transcatheter intracardiac shunt device for heart failure with preserved ejection fraction (REDUCE LAP-HF): A multicentre, open-label, single-arm, phase 1 trial

Hasenfuß, G., Hayward, C., Burkhoff, D., Silvestry, F. E., McKenzie, S., Gustafsson, F., Malek, F., Van Der Heyden, J., Lang, I., Petrie, M. C., Cleland, J. G. F., Leon, M. & Kaye, D. M., 26 Mar 2016, In : The Lancet. 387, 10025, p. 1298-1304 7 p.

Research output: Contribution to journalArticleResearchpeer-review

CORRIGENDUM: N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin

Smith, A. I., Rajapakse, N. W., Kleifeld, O., Lomonte, B., Sikanyika, N. L., Spicer, A. J., Hodgson, W. C., Conroy, P., Small, D. H., Kaye, D. M., Parkington, H. C., Whisstock, J. & Kuruppu, D. M. S., 2016, In : Scientific Reports. 6, Article # 24333, p. 1 - 1 1 p.

Research output: Contribution to journalArticleOther

17 Citations (Scopus)

Diffuse Ventricular Fibrosis on Cardiac Magnetic Resonance Imaging Associates with Ventricular Tachycardia in Patients with Hypertrophic Cardiomyopathy

Mclellan, A. J. A., Ellims, A. H., Prabhu, S., Voskoboinik, A., Iles, L. M., Hare, J. L., Kaye, D. M., Macciocca, I., Mariani, J. A., Kalman, J. M., Taylor, A. J. & Kistler, P. M., 1 May 2016, In : Journal of Cardiovascular Electrophysiology. 27, 5, p. 571-580 10 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Effect of supplemental oxygen exposure on myocardial injury in ST-elevation myocardial infarction

Nehme, Z., Stub, D., Bernard, S., Stephenson, M., Bray, J. E., Cameron, P., Meredith, I. T., Barger, B., Ellims, A. H., Taylor, A. J., Kaye, D. M., Smith, K. & AVOID Investigators, Mar 2016, In : Heart. 102, 6, p. 444-451 8 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Methamphetamine-associated cardiomyopathy: Patterns and predictors of recovery

Voskoboinik, A., Ihle, J. F., Bloom, J. E. & Kaye, D. M., 1 Jun 2016, In : Internal Medicine Journal. 46, 6, p. 723-727 5 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

N-acetylcysteine attenuates the development of cardiac fibrosis and remodeling in a mouse model of heart failure

Giam, B., Chu, P. . Y., Kuruppu, S., Smith, A. I., Horlock, D., Kiriazis, H., Du, X-J., Kaye, D. M. & Rajapakse, N. W., 1 Apr 2016, In : Physiological Reports. 4, 7, 13 p., e12757.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin

Smith, A. I., Rajapakse, N. W., Kleifeld, O., Lomonte, B., Sikanyika, N. L., Spicer, A. J., Hodgson, W. C., Conroy, P. J., Small, D. H., Kaye, D. M., Parkington, H. C., Whisstock, J. C. & Kuruppu, S. M. S., 2 Mar 2016, In : Scientific Reports. 6, 10 p., 22413.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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37 Citations (Scopus)

One-Year Outcomes after Transcatheter Insertion of an Interatrial Shunt Device for the Management of Heart Failure with Preserved Ejection Fraction

Kaye, D. M., Hasenfuß, G., Neuzil, P., Post, M. C., Doughty, R., Trochu, J. N., Kolodziej, A., Westenfeld, R., Penicka, M., Rosenberg, M., Walton, A., Muller, D., Walters, D. L., Hausleiter, J., Raake, P., Petrie, M. C., Bergmann, M., Jondeau, G., Feldman, T. E., van Veldhuisen, D. J. & 4 others, Ponikowski, P., Silvestry, F. E., Burkhoff, D. & Hayward, C., 1 Dec 2016, In : Circulation: Heart Failure. 9, 12, 6 p., e003662.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)

Relationships Among Cognitive Function and Cerebral Blood Flow, Oxidative Stress, and Inflammation in Older Heart Failure Patients

Kure, C. E., Rosenfeldt, F. L., Scholey, A. B., Pipingas, A., Kaye, D. M., Bergin, P. J., Croft, K. D., Wesnes, K. A., Myers, S. P. & Stough, C., 1 Jul 2016, In : Journal of Cardiac Failure. 22, 7, p. 548-559 12 p.

Research output: Contribution to journalArticleResearchpeer-review

56 Citations (Scopus)

The transcardiac gradient of cardio-microRNAs in the failing heart

Marques, F. Z., Vizi, D., Khammy, O., Mariani, J. A. & Kaye, D. M., 1 Aug 2016, In : European Journal of Heart Failure. 18, 8, p. 1000-1008 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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26 Citations (Scopus)

Transcatheter interatrial shunt device for the treatment of heart failure

Feldman, T. E., Komtebedde, J., Burkhoff, D., Massaro, J. P., Maurer, M. S., Leon, M. B., Kaye, D., Silvestry, F. E., Cleland, J. G. F., Kitzman, D., Kubo, S. H., van Veldhuisen, D. J., Kleber, F., Trochu, J. N., Auricchio, A., Gustafsson, F., Hasenfu, G., Ponikowski, P., Filippatos, G., Mauri, L. & 1 others, Shah, S. J., 1 Jul 2016, In : Circulation: Heart Failure. 9, 7

Research output: Contribution to journalArticleResearchpeer-review

2015
5 Citations (Scopus)

Accuracy of echocardiographic cardiac index assessment in subjects with preserved left ventricular ejection fraction

Maeder, M. T., Karapanagiotidis, S., Dewar, E. M. & Kaye, D. M., 1 Nov 2015, In : Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques. 32, 11, p. 1628-1638 11 p.

Research output: Contribution to journalArticleResearchpeer-review

244 Citations (Scopus)

Air versus oxygen in ST-segment-elevation myocardial infarction

Stub, D. A., Smith, K. L., Bernard, S. A., Nehme, Z., Stephenson, M. W., Bray, J. E., Cameron, P., Barger, B., Ellims, A., Taylor, A. J., Meredith, I. T. & Kaye, D. M., 2015, In : Circulation. 131, 24, p. 2143 - 2150 8 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Augmented endothelial l-arginine transport ameliorates pressure-overload-induced cardiac hypertrophy

Rajapakse, N. W., Johnston, T., Kiriazis, H., Chin-Dusting, J. P. F., Du, X-J. & Kaye, D. M., 2015, In : Experimental Physiology. 100, 7, p. 796 - 804 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Augmented endothelial-specific L-arginine transport blunts the contribution of the sympathetic nervous system to obesity induced hypertension in mice

Rajapakse, N. W., Karim, F., Evans, R. G., Kaye, D. M. & Head, G. A., 2015, In : PLoS ONE. 10, 7, 12 p., e0131424.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

Cardiac AAV9 gene delivery strategies in adult canines: Assessment by long-term serial SPECT imaging of sodium iodide symporter expression

Moulay, G., Ohtani, T., Ogut, O., Guenzel, A., Behfar, A., Zakeri, R., Haines, P., Storlie, J., Bowen, L., Pham, L. M., Kaye, D., Sandhu, G., O'Connor, M., Russell, S. J. & Redfield, M., 1 Jul 2015, In : Molecular Therapy. 23, 7, p. 1211-1221 11 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Cardio-protective effects of combined l-arginine and insulin: mechanism and therapeutic actions in myocardial ischemia-reperfusion injury

Venardos, K. M., Rajapakse, N. W., Williams, D., Hoe, L. S., Peart, J. N. & Kaye, D. M., 2015, In : European Journal of Pharmacology. 769, p. 64 - 70 7 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

CXCR4 antagonism attenuates the development of diabetic cardiac fibrosis

Chu, P. Y., Walder, K., Horlock, D., Williams, D., Nelson, E. M., Byrne, M., Jandeleit-Dahm, K., Zimmet, P. & Kaye, D. M., 27 Jul 2015, In : PLoS ONE. 10, 7, e0133616.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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87 Citations (Scopus)

Histological validation of cardiac magnetic resonance analysis of regional and diffuse interstitial myocardial fibrosis

Iles, L. M., Ellims, A. H., Llewellyn, H., Hare, J. L., Kaye, D. M., McLean, C. A. & Taylor, A. J., 1 Jan 2015, In : European Heart Journal Cardiovascular Imaging. 16, 1, p. 14-22 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Left Ventricular Assist Device (LVAD) as a Bridge to Recovery for Tachycardia-Mediated Cardiomyopathy

Stokes, M. B., Saxena, P., Mariani, J. A., Kaye, D. M., Bergin, P. J. & McGiffin, D., 2015, In : Journal of Cardiac Surgery. 30, 11, p. 871 - 873 3 p.

Research output: Contribution to journalArticleOther

23 Citations (Scopus)
18 Citations (Scopus)

Pathogenesis and treatment of the cardiorenal syndrome: Implications of L-arginine-nitric oxide pathway impairment

Rajapakse, N. W., Nanayakkara, S. & Kaye, D. M., 2015, In : Pharmacology and Therapeutics. 154, p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Rationale and Design of the Reduce Elevated Left Atrial Pressure in Patients With Heart Failure (Reduce LAP-HF) Trial

Hasenfuss, G., Gustafsson, F., Kaye, D., Shah, S. J., Burkhoff, D., Reymond, M. C., Komtebedde, J., Hünlich, M. & Reduce LAP-HF Trial Investigators, 1 Jul 2015, In : Journal of Cardiac Failure. 21, 7, p. 594-600 7 p., 3511.

Research output: Contribution to journalArticleResearchpeer-review

225 Citations (Scopus)

Refractory cardiac arrest treated with mechanical CPR, hypothermia, ECMO and early reperfusion (the CHEER trial)

Stub, D. A., Bernard, S. A., Pellegrino, V., Smith, K. L., Walker, T., Sheldrake, J., Hockings, L. E., Shaw, J., Duffy, S., Burrell, A. J. C., Cameron, P., Smit, D. & Kaye, D. M., 2015, In : Resuscitation. 86, p. 88 - 94 7 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Role of mitochondrial dysfunction in hyperglycaemia-induced coronary microvascular dysfunction: protective role of resveratrol

Joshi, M., Williams, D., Horlock, D., Samarasinghe, T. D., Andrews, K. L., Jefferis, A-M., Berger, P. J., Chin-Dusting, J. PF. & Kaye, D. M., 2015, In : Diabetes and Vascular Disease Research. 12, 3, p. 208 - 216 9 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

The use of the AVERT system to limit contrast volume administration during peripheral angiography and intervention

Prasad, A., Ortiz-Lopez, C., Kaye, D. M., Byrne, M., Nanayakkara, S., Ahmed, S. H., Bailey, S. R., Mehran, R., Sethi, S., Banerjee, A. & Eng, M., 1 Dec 2015, In : Catheterization and Cardiovascular Interventions. 86, 7, p. 1228-1233 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2014
11 Citations (Scopus)

Abnormal mitochondrial L-arginine transport contributes to the pathogenesis of heart failure and rexoygenation injury

Williams, D., Venardos, K., Byrne, M., Joshi, M., Horlock, D., Lam, N. T., Gregorevic, P., McGee, S. L. & Kaye, D. M., 2014, In : PLoS ONE. 9, 8, 11 p., e104643.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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43 Citations (Scopus)

A comprehensive evaluation of myocardial fibrosis in hypertrophic cardio myopathy with cardiacmagnetic resonance imaging: Linking genotype with fibrotic phenotype

Ellims, A. H., Iles, L. M., Ling, L-H., Chong, B., Macciocca, I., Slavin, G. S., Hare, J. L., Kaye, D. M., Marasco, S. F., McLean, C. A., James, P. A., Du Sart, D. & Taylor, A. J., Oct 2014, In : European Heart Journal Cardiovascular Imaging. 15, 10, p. 1108-1116 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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17 Citations (Scopus)

Augmented endothelial-specific L-arginine transport prevents obesity-induced hypertension

Rajapakse, N. W., Karim, F., Straznicky, N., Fernandez, S., Evans, R. G., Head, G. A. & Kaye, D. M., 2014, In : Acta Physiologica. 212, 1, p. 39 - 48 10 p.

Research output: Contribution to journalArticleResearchpeer-review

99 Citations (Scopus)

Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair

Furtado, M. B., Da Costa, M., Pranoto, E. M. A., Salimova, E., Pinto, R. I. A., Lam, N. T., Park, A., Snider, P., Chandran, A., Harvey, R. P., Boyd, R. L., Conway, S., Pearson, J. T., Kaye, D. M. & Rosenthal, N. A., 2014, In : Circulation Research. 114, 9, p. 1422 - 1434 13 p.

Research output: Contribution to journalArticleResearchpeer-review