Projects per year
Personal profile
Biography
Professor David Kaye is an NHMRC Principal Research Fellow and a Heart Failure/Transplant physician at the Alfred Hospital Melbourne. Prof Kaye’s research has been directed towards the characterisation of the pathophysiology of heart failure, with a particular emphasis on the identification of novel mechanisms that can be targeted for therapeutic intervention. Prof Kaye has been highly successful in the generation of intellectual property leading to commercial and clinical outcomes.
He is an Adjunct Professor at Monash University. He leads the Heart Failure Research laboratory, comprising a number of senior post-docs, RAs, PhD students and BSc(Hons) students. Prof Kaye is Chair of the Medical Advisory Boards for Opsrey Medical and Cardiora Pty Ltd, both companies which he founded based upon intellectual property he generated.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Cardiology
- Pathophysiology
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Guanethidine for Pulmonary Hypertension Patients with Heart Failure with Preserved Ejection Fraction (PH-HFpEF)
Kaye, D. (Primary Chief Investigator (PCI))
29/09/25 → 1/09/27
Project: Research
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Project #31 - MCS Stakeholder Insights for MCS Devices
Wrigley, C. (Primary Chief Investigator (PCI)), Gregory, S. (Chief Investigator (CI)), Hayward, C. S. (Chief Investigator (CI)) & Kaye, D. (Chief Investigator (CI))
1/07/25 → 1/05/28
Project: Research
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BiVACOR® Total Artificial Heart Clinical Feasibility Study
Kaye, D. (Primary Chief Investigator (PCI))
7/05/25 → 6/05/27
Project: Research
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Project #18 - Development of Remote Monitoring Systems for MCS Devices
Lovell, N. (Primary Chief Investigator (PCI)), Kaye, D. (Chief Investigator (CI)), Stevens, M. C. (Chief Investigator (CI)), Brown, P. (Chief Investigator (CI)), Timms, D. (Chief Investigator (CI)), Tansley, G. D. (Chief Investigator (CI)), Gregory, S. (Chief Investigator (CI)), Hayward, C. S. (Chief Investigator (CI)) & Wrigley, C. (Chief Investigator (CI))
1/09/24 → 31/05/28
Project: Research
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Optimising chest pain pathways that ensure earlier access to definitive care for patients in remote and rural communities
Stub, D. (Primary Chief Investigator (PCI)), Nehme, Z. (Chief Investigator (CI)), Cullen, L. A. (Chief Investigator (CI)), Chew, D. (Chief Investigator (CI)), Zaman, S. (Chief Investigator (CI)), Ball, J. (Chief Investigator (CI)), Chow, C. K. (Chief Investigator (CI)), Kaye, D. (Chief Investigator (CI)), Briffa, T. (Chief Investigator (CI)), Cameron, P. (Chief Investigator (CI)), Nanayakkara, S. (Chief Investigator (CI)), Bray, J. (Chief Investigator (CI)), Finn, J. (Chief Investigator (CI)), Cartledge, S. (Chief Investigator (CI)), Reid, C. (Chief Investigator (CI)), Hall, T. (Associate Investigator (AI)), Salathiel, R. (Associate Investigator (AI)), Patel, H. (Associate Investigator (AI)), Zoungas, S. (Associate Investigator (AI)), Zomer, E. (Associate Investigator (AI)), Talic, S. (Associate Investigator (AI)), Nelson, A. (Associate Investigator (AI)), Fernando, H. M. (Associate Investigator (AI)), Sher, L. (Associate Investigator (AI)), Freak-Poli, R. (Associate Investigator (AI)), Dinh, D. (Associate Investigator (AI)), Kasza, J. (Associate Investigator (AI)), Bowden, R. (Associate Investigator (AI)) & Bodnar, D. (Associate Investigator (AI))
1/03/24 → 29/02/28
Project: Research
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Beta-Blocker Therapy After Myocardial Infarction
Cataldo Miranda, P., Gasevic, D., Trin, C., Stub, D., Zoungas, S., Kaye, D. M., Orman, Z., Eliakundu, A. L. & Talic, S., Mar 2025, In: JACC: Advances. 4, 3, 14 p., 101582.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access7 Citations (Scopus) -
Biological Merits and Antibiofilm Mechanisms of Action of a Specially Designed Double-Shelled Microparticle
Sheng, C., Zhou, C., Guo, M., McGiffin, D. C., Kaye, D. M., Truong, V. X., Qian, C., Kostoulias, X., Peleg, A. Y., Forsythe, J. S. (Leading Author), Scott, T. F. (Leading Author) & Qu, Y. (Leading Author), 26 Aug 2025, In: ACS Omega. 10, 35, p. 40271-40281 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Cell Type–Specific Secretome Analysis Reveals Liver-Heart Crosstalk in HFpEF
Schütte, J. P., Markus, N., Grein, S., Kamuf-Schenk, V., Stroh, C., Rettel, M., Stein, F., Fischer, J., Löwenthal, Z., Leiner, J., Wang, B. H., Kaye, D. M., Zylla, M. M., Frey, N. & Völkers, M., 23 May 2025, In: Circulation Research. 136, 11, p. 1516-1518 3 p.Research output: Contribution to journal › Letter › Other › peer-review
1 Citation (Scopus) -
Coronary artery bypass grafting vs. percutaneous coronary intervention in severe ischaemic cardiomyopathy: long-term survival
Bloom, J. E., Vogrin, S., Reid, C. M., Ajani, A. E., Clark, D. J., Freeman, M., Hiew, C., Brennan, A., Dinh, D., Williams-Spence, J., Dawson, L. P., Noaman, S., Chew, D. P., Oqueli, E., Cox, N., McGiffin, D., Marasco, S., Skillington, P., Royse, A. & Stub, D. & 2 others, , 1 Jan 2025, In: European Heart Journal. 46, 1, p. 72-80 9 p.Research output: Contribution to journal › Article › Research › peer-review
23 Citations (Scopus) -
Development and Evaluation of a Novel Drainage Cannula for Venoarterial Extracorporeal Membrane Oxygenation
Wickramarachchi, A., Shirejini, S. Z., Vatani, A., Rana, A., Khamooshi, M., Šeman, M., Liao, S., Jap, E., Nguyen, T. H., Alt, K., Burrell, A., Pellegrino, V. A., Kaye, D. M., Hagemeyer, C. E. & Gregory, S. D., Mar 2025, In: ASAIO Journal. 71, 3, p. 235-244 10 p.Research output: Contribution to journal › Article › Research › peer-review