Projects per year
Personal profile
Biography
Professor David Kaye is an NHMRC Principal Research Fellow and a Heart Failure/Transplant physician at the Alfred Hospital Melbourne. Prof Kaye’s research has been directed towards the characterisation of the pathophysiology of heart failure, with a particular emphasis on the identification of novel mechanisms that can be targeted for therapeutic intervention. Prof Kaye has been highly successful in the generation of intellectual property leading to commercial and clinical outcomes.
He is an Adjunct Professor at Monash University. He leads the Heart Failure Research laboratory, comprising a number of senior post-docs, RAs, PhD students and BSc(Hons) students. Prof Kaye is Chair of the Medical Advisory Boards for Opsrey Medical and Cardiora Pty Ltd, both companies which he founded based upon intellectual property he generated.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Cardiology
- Pathophysiology
Network
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A Phase 2, Double-blind, Randomized, Placebo-controlled, 4-arm Study to Investigate Symptoms, Function, Health-Related Quality of Life, and Safety, With Repeated Subcutaneous Administration of Ponsegromab Versus Placebo in Adult Participants With Heart Failure”, and with brief title: “A Phase 2 Study of the Effects of Ponsegromab on Health-Related Quality of Life and Safety in Patients With Heart Failure (GARDEN-TIMI 74)
Kaye, D., Jayasinghe, S. R., Kumarasinghe, G., Stokes, M. B. & Arstall, M.
13/12/22 → 7/11/24
Project: Research
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Development of a Novel Photo-Angioplasty Device for the Treatment of Occlusive Peripheral Vascular Disease
Dear, A., Kaye, D., Byrne, M. J., Thompson, P., Gaspari, T. & Thissen, H.
1/01/22 → 31/12/24
Project: Research
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Noradrenaline Versus Adrenaline in the initial management shock
Stub, D., Kaye, D., Smith, K. & Bernard, S.
1/07/21 → 30/06/23
Project: Research
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Epidemiology, outcomes and predictors of mortality in patients transported by ambulance for dyspnoea: A population-based cohort study
Zhou, J., Andrew, E., Dawson, L., Bloom, J. E., Nehme, Z., Okyere, D., Cox, S., Anderson, D., Stephenson, M., Smith, K., Kaye, D. & Stub, D., Feb 2023, In: EMA - Emergency Medicine Australasia. 35, 1, p. 48-55 8 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Meta-Analysis on Drug and Device Therapy of New York Heart Association Functional Class IV Heart Failure With Reduced Ejection Fraction
Batchelor, R. J., Nan Tie, E., Romero, L., Hopper, I. & Kaye, D. M., 1 Feb 2023, In: American Journal of Cardiology. 188, p. 52-60 9 p.Research output: Contribution to journal › Article › Research › peer-review
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Use of a novel smartphone-based application tool for enrolment and randomisation in pre-hospital clinical trials
Bloom, J. E., Partovi, A., Bernard, S., Okyere, D., Heritier, S., Mahony, E., Eliakundu, A. L., Dawson, L. P., Voskoboinik, A., Anderson, D., Ball, J., Chan, W., Kaye, D. M., Nehme, Z. & Stub, D., Apr 2023, (Accepted/In press) In: Resuscitation. 6 p., 109787.Research output: Contribution to journal › Comment / Debate › Other › peer-review
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Adverse Impact of Peri-Procedural Stroke in Patients Who Underwent Percutaneous Coronary Intervention
Wexler, N. Z., Vogrin, S., Brennan, A. L., Noaman, S., Al-Mukhtar, O., Haji, K., Bloom, J. E., Dinh, D. T., Zheng, W. C., Shaw, J. A., Duffy, S. J., Lefkovits, J., Reid, C. M., Stub, D., Kaye, D. M., Cox, N. & Chan, W., 20 Aug 2022, (Accepted/In press) In: The American Journal of Cardiology. 7 p.Research output: Contribution to journal › Article › Research › peer-review
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A gold nanowire-integrated soft wearable system for dynamic continuous non-invasive cardiac monitoring
Gong, S., Yap, L. W., Zhang, Y., He, J., Yin, J., Marzbanrad, F., Kaye, D. M. & Cheng, W., 1 Jun 2022, In: Biosensors and Bioelectronics. 205, 9 p., 114072.Research output: Contribution to journal › Article › Research › peer-review
8 Citations (Scopus)