1998 …2024
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Personal profile


Professor David Kaye is an NHMRC Principal Research Fellow and a Heart Failure/Transplant physician at the Alfred Hospital Melbourne. Prof Kaye’s research has been directed towards the characterisation of the pathophysiology of heart failure, with a particular emphasis on the identification of novel mechanisms that can be targeted for therapeutic intervention. Prof Kaye has been highly successful in the generation of intellectual property leading to commercial and clinical outcomes.

He is an Adjunct Professor at Monash University. He leads the Heart Failure Research laboratory, comprising a number of senior post-docs, RAs, PhD students and BSc(Hons) students. Prof Kaye is Chair of the Medical Advisory Boards for Opsrey Medical and Cardiora Pty Ltd, both companies which he founded based upon intellectual property he generated.

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Projects 2016 2024

Research Output 1998 2020

Impact of a model of care for heart failure in‐patients to reduce variation in care – a quality improvement project

Hopper, I., Easton, K., Bader, I., Campbell, J., Busija, L., Markey, P., Bergin, P. J. & Kaye, D. M., 11 Feb 2020, (Accepted/In press) In : Internal Medicine Journal. 29 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Comparison of Magnetic Resonance Analysis of Myocardial Scarring With Biomarker Release Following S-T Elevation Myocardial Infarction

Costello, B. T., Stub, D., Hare, J., Ellims, A. H., Wang, X., Smith, K., Bernard, S., Nehme, Z., Stephenson, M., Bray, J. E., Cameron, P., Barger, B., Meredith, I. T., Kaye, D. M., Iles, L., Taylor, A. J. & on behalf of the AVOID Investigators, Mar 2019, In : Heart Lung and Circulation. 28, 3, p. 397-405 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Intergenerational Prevention Of Heart Failure Through Maternal Intake Of High Fibre

Jama, H. A., Shihata, W., Ziemann, M. D., Donner, D. G., Kiriazis, H., Du, X-J., El-Osta, A., Mackay, C. R., Kaye, D. M. & Coelho Marques, F., Feb 2019. 1 p.

Research output: Contribution to conferenceAbstract

1 Citation (Scopus)

Molecular mechanisms of protein-bound uremic toxin-mediated cardiac, renal and vascular effects: underpinning intracellular targets for cardiorenal syndrome therapy

Savira, F., Magaye, R., Hua, Y., Liew, D., Kaye, D., Marwick, T. & Wang, B. H., 15 Jun 2019, In : Toxicology Letters. 308, p. 34-49 16 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

5 Citations (Scopus)

The gut microbiota and blood pressure in experimental models

Jama, H. A., Kaye, D. M. & Marques, F. Z., 1 Mar 2019, In : Current Opinion in Nephrology and Hypertension. 28, 2, p. 97-104 8 p.

Research output: Contribution to journalArticleResearchpeer-review