Projects per year
Personal profile
Biography
Professor David Kaye is an NHMRC Principal Research Fellow and a Heart Failure/Transplant physician at the Alfred Hospital Melbourne. Prof Kaye’s research has been directed towards the characterisation of the pathophysiology of heart failure, with a particular emphasis on the identification of novel mechanisms that can be targeted for therapeutic intervention. Prof Kaye has been highly successful in the generation of intellectual property leading to commercial and clinical outcomes.
He is an Adjunct Professor at Monash University. He leads the Heart Failure Research laboratory, comprising a number of senior post-docs, RAs, PhD students and BSc(Hons) students. Prof Kaye is Chair of the Medical Advisory Boards for Opsrey Medical and Cardiora Pty Ltd, both companies which he founded based upon intellectual property he generated.
Research area keywords
- Cardiology
- Pathophysiology
Network
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Development of a Novel Photo-Angioplasty Device for the Treatment of Occlusive Peripheral Vascular Disease
Dear, A., Kaye, D., Byrne, M. J., Thompson, P., Gaspari, T. & Thissen, H.
1/01/22 → 31/12/24
Project: Research
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Noradrenaline Versus Adrenaline in the initial management shock
Stub, D., Kaye, D., Smith, K. & Bernard, S.
1/07/21 → 30/06/23
Project: Research
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Improving the Long Term Outcomes after Extracorporeal Membrane Oxygenation for Acute Heart Failure
Burrell, A., Hodgson, C., Udy, A. & Kaye, D.
1/01/21 → 31/12/22
Project: Research
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Antiplatelet Removal and Hemocompatibility EventS with the HeartMate 3 Pump (ARIES HM3).
Kaye, D. & Hayward, C.
1/07/20 → 31/12/23
Project: Research
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Clinical risk prediction model for 30-day all-cause re-hospitalisation or mortality in patients hospitalised with heart failure
Driscoll, A., Romaniuk, H., Dinh, D., Amerena, J., Brennan, A., Hare, D. L., Kaye, D., Lefkovits, J., Lockwood, S., Neil, C., Prior, D., Reid, C. M. & Orellana, L., 1 Mar 2022, In: International Journal of Cardiology. 350, p. 69-76 8 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Improved drainage cannula design to reduce thrombosis in veno-arterial extracorporeal membrane oxygenation
Vatani, A., Liao, S., Burrell, A. J. C., Carberry, J., Azimi, M., Steinseifer, U., Arens, J., Soria, J., Pellegrino, V., Kaye, D. & Gregory, S. D., Feb 2022, In: ASAIO journal (American Society for Artificial Internal Organs : 1992). 68, 2, p. 205-213 9 p.Research output: Contribution to journal › Article › Research › peer-review
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Association between pre-hospital chest pain severity and myocardial injury in ST elevation myocardial infarction: A post-hoc analysis of the AVOID study
Fernando, H., Nehme, Z., Peter, K., Bernard, S., Stephenson, M., Bray, J. E., Myles, P. S., Stub, R., Cameron, P., Ellims, A. H., Taylor, A. J., Kaye, D. M., Smith, K., Stub, D. & for the AVOID investigators, Dec 2021, In: IJC Heart and Vasculature. 37, 6 p., 100899.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Attenuating PI3K/Akt- mTOR pathway reduces dihydrosphingosine 1 phosphate mediated collagen synthesis and hypertrophy in primary cardiac cells
Magaye, R. R., Savira, F., Hua, Y., Xiong, X., Huang, L., Reid, C., Flynn, B. L., Kaye, D., Liew, D. & Wang, B. H., May 2021, In: International Journal of Biochemistry & Cell Biology. 134, 16 p., 105952.Research output: Contribution to journal › Article › Research › peer-review
6 Citations (Scopus) -
Comparison of Circulatory Unloading Techniques for Venoarterial Extracorporeal Membrane Oxygenation
Stephens, A. F., Wanigasekara, D., Pellegrino, V. A., Burrell, A. J. C., Marasco, S. F., Kaye, D. M., Steinseifer, U. & Gregory, S. D., Jun 2021, In: ASAIO journal (American Society for Artificial Internal Organs : 1992). 67, 6, p. 623-631 9 p.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus)