• 23 Innovation Walk, 77

    3800 Monash

    Australia

1983 …2021

Research output per year

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Research Output

1983

Cloning of the Structural Genes of the Escherichia coli Adenosinetriphosphatase Complex

Jans, D. A. & Gibson, F., 1 Jan 1983, In : Methods in Enzymology. 97, C, p. 176-187 12 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Mutations in the uncE gene affecting assembly of the c-subunit of the adenosine triphosphatase of Escherichia coli.

Jans, D. A., Fimmel, A. L., Langman, L., James, L. B., Downie, J. A., Senior, A. E., Ash, G. R., Gibson, F. & Cox, G. B., 1 Jan 1983, In : The Biochemical journal. 211, 3, p. 717-726 10 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Oxidative phosphorylation by mutant Escherichia coli membranes with impaired proton permeability.

Cox, G. B., Jans, D. A., Gibson, F., Langman, L., Senior, A. E. & Fimmel, A. L., 1 Jan 1983, In : The Biochemical journal. 216, 1, p. 143-150 8 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

The F1F0-ATPase of Escherichia coli. Substitution of proline by leucine at position 64 in the c-subunit causes loss of oxidative phosphorylation.

Fimmel, A. L., Jans, D. A., Langman, L., James, L. B., Ash, G. R., Downie, J. A., Senior, A. E., Gibson, F. & Cox, G. B., 1 Jan 1983, In : The Biochemical journal. 213, 2, p. 451-458 8 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)
1984

An acidic or basic amino acid at position 26 of the b subunit of Escherichia coli F1F0-ATPase impairs membrane proton permeability: Suppression of the uncF469 nonsense mutation

Jans, D. A., Hatch, L., Fimmel, A. L., Gibson, F. & Cox, G. B., 1 Dec 1984, In : Journal of Bacteriology. 160, 2, p. 764-770 7 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

An additional acidic residue in the membrane portion of the b-subunit of the energy-transducing adenosine triphosphatase of Escherichia coli affects both assembly and function.

Jans, D. A., Fimmel, A. L., Hatch, L., Gibson, F. & Cox, G. B., 1 Jan 1984, In : The Biochemical journal. 221, 1, p. 43-51 9 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Hypothesis the mecanism of ATP synthase conformational change by rotation of the b-subunit

Cox, G. B., Jans, D. A., Fimmel, A. L., Gibson, F. & Hatch, L., 17 Dec 1984, In : BBA Reviews On Bioenergetics. 768, 3-4, p. 201-208 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

83 Citations (Scopus)

Structural gene for the phosphate-repressible phosphate-binding protein of Escherichia coli has its own promoter: Complete nucleotide sequence of the phoS gene

Surin, B. P., Jans, D. A., Fimmel, A. L., Shaw, D. C., Cox, G. B. & Rosenberg, H., 3 May 1984, In : Journal of Bacteriology. 157, 3, p. 772-778 7 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)
1985

Complementation between uncF alleles affecting assembly of the F1F0-ATPase complex of Escherichia coli

Jans, D. A., Hatch, L., Fimmel, A. L., Gibson, F. & Cox, G. B., 7 Aug 1985, In : Journal of Bacteriology. 162, 1, p. 420-426 7 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

The F1F0-ATPase of Escherichia coli. The substitution of alanine by threonine at position 25 in the c-subunit affects function but not assembly

Fimmel, A. L., Jans, D. A., Hatch, L., James, L. B., Gibson, F. & Cox, G. B., 17 Jul 1985, In : BBA - Bioenergetics. 808, 2, p. 252-258 7 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)
1986

Expression cloning of a cDNA encoding the type II regulatory subunit of the cAMP-dependent protein kinase

Hemmings, B. A., Schwarz, M., Rao Adavani, S. & Jans, D. A., 15 Dec 1986, In : FEBS Letters. 209, 2, p. 219-222 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
23 Citations (Scopus)

Isolation of a mutant LLC‐PK1 cell line defective in hormonal responsiveness: A pleiotropic lesion in receptor function

JANS, D. A., RESINK, T. J., WILSON, L. E., REICH, E. & HEMMINGS, B. A., 1 Jan 1986, In : European Journal of Biochemistry. 160, 2, p. 407-412 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
25 Citations (Scopus)

LLC-PK1 cell mutants in cAMP metabolism respond normally to phorbol esters

Jans, D. A. & Hemmings, B. A., 1 Sep 1986, In : FEBS Letters. 205, 1, p. 127-131 5 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)
1987

Characterization of two mutants of the LLC‐PK1 porcine kidney cell line affected in the catalytic subunit of the cAMP‐dependent protein kinase

BOTTERELL, S. H., JANS, D. A. & HEMMINGS, B. A., 1 Jan 1987, In : European Journal of Biochemistry. 164, 1, p. 39-44 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
20 Citations (Scopus)

Complementation between LLC‐PK1 mutants affected in polypeptide hormone‐receptor function

JANS, D. A., RESINK, T. J. & HEMMINGS, B. A., 1 Jan 1987, In : European Journal of Biochemistry. 162, 3, p. 571-576 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
8 Citations (Scopus)

Dependence of urokinase-type-plasminogen-activator induction on cyclic AMP-dependent protein kinase activation in LLC-PK1 cells

Jans, D. A., Resink, T. J. & Hemmings, B. A., 1 Jan 1987, In : Biochemical Journal. 243, 2, p. 413-418 6 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Isolation of a cDNA and characterization of the 5′ flanking region of the gene encoding the type I regulatory subunit of the cAMP‐dependent protein kinase

NOWAK, I., SEIPEL, K., SCHWARZ, M., JANS, D. A. & HEMMINGS, B. A., 1 Jan 1987, In : European Journal of Biochemistry. 167, 1, p. 27-33 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
51 Citations (Scopus)

Long-term stimulation of cAMP production in LLC-PK1 pig kidney epithelial cells by salmon calcitonin or a photoactivatable analogue of vasopressin

Jans, D. A., Gajdas, E. L., Dierks-Ventling, C., Hemmings, B. A. & Fahrenholz, F., 1 Oct 1987, In : BBA - Molecular Cell Research. 930, 3, p. 392-400 9 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Pathway of urokinase-type plasminogen activator induction in the T47D and LLC-PK1, cell lines

Jans, D. A., Dierks-Ventling, C. & Hemmings, B. A., 1 Jan 1987, In : Experimental Cell Research. 172, 1, p. 76-83 8 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Recombinant type I regulatory subunit of the cAMP-dependent protein kinase is biologically active

Oehen, S., Parsons, J. A., Jans, D. A. & Hemmings, B. A., 10 Aug 1987, In : FEBS Letters. 220, 1, p. 47-51 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
1988
7 Citations (Scopus)

Codominant expression of a mutation affecting the cAMP-dependent protein kinase catalytic subunit in somatic cell hybrids of LLC-PK1 cells

Jans, D. A., Botterell, S. H. & Hemmings, B. A., 1 Jan 1988, In : Experimental Cell Research. 176, 1, p. 129-140 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Electroporation of Cultured adult rat hepatocytes with the c-myc gene potentiates DNA synthesis in response to epidermal growth factor

Muakkassah-kelly, S. F., Jans, D. A., Lydon, N., Bieri, F., Waechter, F., Bentley, P. & Staubli, W., 1 Jan 1988, In : Experimental Cell Research. 178, 2, p. 296-306 11 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)
1989

The adenylate cyclase-coupled vasopressin V2-receptor is highly laterally mobile in membranes of LLC-PK1 renal epithelial cells at physiological temperature

Jans, D. A., Peters, R., Zsigo, J. & Fahrenholz, F., 1 Jan 1989, In : The EMBO Journal. 8, 9, p. 2481-2488 8 p.

Research output: Contribution to journalArticleResearchpeer-review

47 Citations (Scopus)
1990

Ammonium chloride affects receptor number and lateral mobility of the vasopressin V2-type receptor in the plasma membrane of LLC-PK1 renal epithelial cells: Role of the cytoskeleton

Jans, D. A., Peters, R., Jans, P. & Fahrenholz, F., 1 Jan 1990, In : Experimental Cell Research. 191, 1, p. 121-128 8 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

An inverse relationship between receptor internalization and the fraction of laterally mobile receptors for the vasopressin renal-type V2-receptor. An active role for receptor immobilization in down-regulation?

Jans, D. A., Peters, R. & Fahrenholz, F., 12 Nov 1990, In : FEBS Letters. 274, 1-2, p. 223-226 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
5 Citations (Scopus)

A system to select for mutant LLC-PK1 cells affected in camp mediated hormonal response using a photoactivatable analogue of vasopressin

Luzius, H., Jans, D. A. & Fahrenholz, F., 1 Jan 1990, In : Journal of Receptors and Signal Transduction. 10, 1-2, p. 61-80 20 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Biotinyl analogues of vasopressin as biologically active probes for vasopressin receptor expression in cultured cells

Jans, D. A., Bergmann, L., Peters, R. & Fahrenholz, F., 10 Sep 1990, In : Journal of Biological Chemistry. 265, 24, p. 14599-14605 7 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Derivatives of somatic cell hybrids which carry the human gene locus for nephrogenic diabetes insipidus (NDI) express functional vasopressin renal V2-type receptors

Jans, D. A., Van Oost, B. A., Ropers, H. H. & Fahrenholz, F., 11 Oct 1990, In : Journal of Biological Chemistry. 265, 26, p. 15379-15382 4 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Lateral mobility of the phospholipase C-activating vasopressin V1-type receptor in A7r5 smooth muscle cells: A comparison with the adenylate cyclase-coupled V2-receptor

Jans, D. A., Peters, R. & Fahrenholz, F., 1 Dec 1990, In : The EMBO Journal. 9, 9, p. 2693-2699 7 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)
1991

A novel LLC-PK1 renal epithelial cell mutant impaired in in vivo down-regulation of cAMP-mediated hormonal response

Jans, D. A., Resink, T. J. & Hemmings, B. A., 1 Jan 1991, In : Archives of Biochemistry and Biophysics. 285, 2, p. 377-381 5 p.

Research output: Contribution to journalArticleResearchpeer-review

cAMP-dependent protein kinase activation affects vasopressin V2-receptor number and internalization in LLC-PK1 renal epithelial cells

Jans, D. A. & Hemmings, B. A., 9 Apr 1991, In : FEBS Letters. 281, 1-2, p. 267-271 5 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Isolation and genetic characterization of a renal epithelial cell mutant defective in vasopressin (V2) receptor binding and function

Luzius, H., Jans, D. A., Jans, P. & Fahrenholz, F., 1 Jan 1991, In : Experimental Cell Research. 195, 2, p. 478-484 7 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Mechanisms of cAMP-mediated gene induction: Examination of renal epithelial cell mutants affected in the catalytic subunit of the cAMP-dependent protein kinase

Pearson, D., Nigg, E. A., Nagamine, Y., Jans, D. A. & Hemmings, B. A., 1 Jan 1991, In : Experimental Cell Research. 192, 1, p. 315-318 4 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Monensin-resistant LLC-PK1 cell mutants are affected in recycling of the adenylate cyclase-stimulating vasopressin V2-receptor

Jans, D. A., Jans, P., Luzius, H. & Fahrenholz, F., 1 Jan 1991, In : Molecular and Cellular Endocrinology. 81, 1-3, p. 165-174 10 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Overexpression of the α-type protein kinase (PK) C in LLC-PK1 cells does not lead to a proportional increase in the induction of two 12-O-tetradecanoylphorbol-13-acetate-inducible genes

Wartmann, M., Jans, D. A., Parker, P. J., Nagamine, Y., Hemmings, B. A., Jaken, S., Eppenberger, U. & Fabbro, D., 1 Jan 1991, In : Molecular Biology of the Cell. 2, 6, p. 491-502 12 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

p34cdc2-mediated phosphorylation at T124 inhibits nuclear import of SV-40 T antigen proteins

Jans, D. A., Ackermann, M. J., Bischoff, J. R., Beach, D. H. & Peters, R., 1 Jan 1991, In : Journal of Cell Biology. 115, 5, p. 1203-1212 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
178 Citations (Scopus)

The chloroplast β-subunit allows assembly of the Escherichia coli F0 portion of the energy transducing adenosine triphosphatase

Munn, A. L., Whitfeld, P. R., Bottomley, W., Hudson, G. S., Jans, D. A., Gibson, F. & Cox, G. B., 27 Sep 1991, In : BBA - Bioenergetics. 1060, 1, p. 82-88 7 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

The rate of nuclear cytoplasmic protein transport is determined by the casein kinase II site flanking the nuclear localization sequence of the SV40 T-antigen

Rihs, H. P., Jans, D. A., Fan, H. & Peters, R., 1 Dec 1991, In : The EMBO Journal. 10, 3, p. 633-639 7 p.

Research output: Contribution to journalArticleResearchpeer-review

289 Citations (Scopus)

Vasopressin V2-receptor mobile fraction and ligand-dependent adenylate cyclase activity are directly correlated in LLC-PK1 renal epithelial cells

Jans, D. A., Peters, R., Jans, P. & Fahrenholz, F., 1 Jan 1991, In : Journal of Cell Biology. 114, 1, p. 53-60 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
18 Citations (Scopus)
1992

A low affinity vasopressin v2-receptor in inherited nephrogenic diabetes insipidus

Luzius, H., Jans, D. A., Grünbaum, E. G., Moritz, A., Rascher, W. & Fahrenholz, F., 1 Jan 1992, In : Journal of Receptors and Signal Transduction. 12, 3, p. 351-368 18 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Generation of anti-idiotypic monoclonal antibodies recognizing vasopressin receptors in cultured cells and kidney sections

Jurzak, M., Jans, D. A., Haase, W., Peters, R. & Fahrenholz, F., 1 Jan 1992, In : Experimental Cell Research. 203, 1, p. 182-191 10 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)
12 Citations (Scopus)

Receptor-mediated endocytosis and nuclear transport of a transfecting DNA construct

Rosenkranz, A. A., Yachmenev, S. V., Jans, D. A., Serebryakova, N. V., Murav'ev, V. I., Peters, R. & Sobolev, A. S., 1 Jan 1992, In : Experimental Cell Research. 199, 2, p. 323-329 7 p.

Research output: Contribution to journalArticleResearchpeer-review

95 Citations (Scopus)

The mobile receptor hypothesis revisited: a mechanistic role for hormone receptor lateral mobility in signal transduction

Jans, D. A., 11 Dec 1992, In : BBA - Reviews on Biomembranes. 1113, 3-4, p. 271-276 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

27 Citations (Scopus)
1993

Oxytocin induced cAMP-dependent protein kinase activation and urokinase-type plasminogen activator production in LLC-PK1 renal epithelial cells is mediated by the vasopressin V2-receptor

Jans, D. A., Pavo, I. & Fahrenholz, F., 4 Jan 1993, In : FEBS Letters. 315, 2, p. 134-138 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
11 Citations (Scopus)

THE USE OF INTERNALIZABLE DERIVATIVES OF CHLORIN E6 FOR INCREASING ITS PHOTOSENSITIZING ACTIVITY

Akhlynina, T. V., Rosenkranz, A. A., Jans, D. A., Gulak, P. V., Sererryakova, N. V. & Sobolev, A. S., 1 Jan 1993, In : Photochemistry and Photobiology. 58, 1, p. 45-48 4 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)
1994

Lateral mobility of the antagonist-occupied V2 vasopressin receptor in membranes of renal epithelial cells

Pavo, I., Jans, D. A., Peters, R., Penke, B. & Fahrenholz, F., 8 Sep 1994, In : BBA - Molecular Cell Research. 1223, 2, p. 240-246 7 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Negative charge at the casein kinase II site flanking the nuclear localization signal of the SV40 large T-antigen is mechanistically important for enhanced nuclear import

Jans, D. A. & Jans, P., 1 Oct 1994, In : Oncogene. 9, 10, p. 2961-2968 8 p.

Research output: Contribution to journalArticleResearchpeer-review

82 Citations (Scopus)

Nuclear signaling pathways for polypeptide ligands and their membrane receptors?

Jans, D. A., 31 Aug 1994, In : The FASEB Journal. 8, 11, p. 841-847 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

128 Citations (Scopus)