Research Output 1981 2018

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2018

Comparative analysis of activins A and B in the adult mouse epididymis and vas deferens

Wijayarathna, R., de Kretser, D. M., Sreenivasan, R., Ludlow, H., Middendorff, R., Meinhardt, A., Loveland, K. L. & Hedger, M. P. 1 Jan 2018 In : Reproduction. 155, p. 15-23 14 p.

Research output: Research - peer-reviewArticle

Weighting of orthostatic intolerance time measurements with standing difficulty score stratifies ME/CFS symptom severity and analyte detection

Richardson, A. M., Lewis, D. P., Kita, B., Ludlow, H., Groome, N. P., Hedger, M. P., de Kretser, D. M. & Lidbury, B. A. 12 Apr 2018 In : Journal of Translational Medicine. 16, 1, 11 p., 97

Research output: Research - peer-reviewArticle

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2017

Activin and follistatin interactions in the male reproductive tract: Activin expression and morphological abnormalities in mice lacking follistatin 288

Wijayarathna, R., Sarraj, M. A., Genovese, R., Girling, J. E., Michel, V., Ludlow, H., Loveland, K. L., Meinhardt, A., de Kretser, D. M. & Hedger, M. P. May 2017 In : Andrology. 5, 3, p. 578-588 11 p.

Research output: Research - peer-reviewArticle

Activin Biology After Lung Transplantation

Westall, G. P., Snell, G. I., Loskot, M., Levvey, B., O'Hehir, R. E., Hedger, M. P. & de Kretser, D. M. May 2017 In : Transplantation Direct. 3, 6, e159

Research output: Research - peer-reviewArticle

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Activin B is a novel biomarker for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) diagnosis: A cross sectional study

Lidbury, B. A., Kita, B., Lewis, D. P., Hayward, S., Ludlow, H., Hedger, M. P. & de Kretser, D. M. 16 Mar 2017 In : Journal of Translational Medicine. 15, 1, 60

Research output: Research - peer-reviewArticle

Open Access
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Follistatin and the breast implant capsule

Frenkiel, B. A., Temple-Smith, P., Kretser, D. D. & Southwick, G. J. 2017 In : Plastic and Reconstructive Surgery - Global Open. 5, 3, 9 p., 1258

Research output: Research - peer-reviewArticle

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Follistatin attenuates radiation-induced fibrosis in a murine model

Forrester, H. B., De Kretser, D. M., Leong, T., Hagekyriakou, J. & Sprung, C. N. 1 Mar 2017 In : PLoS ONE. 12, 3, e0173788

Research output: Research - peer-reviewArticle

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Hyperglycemia is associated with reduced testicular function and activin dysregulation in the Ins2Akita+/- mouse model of type 1 diabetes

Maresch, C. C., Stute, D. C., Ludlow, H., Hammes, H. P., de Kretser, D. M., Hedger, M. P. & Linn, T. 5 May 2017 In : Molecular and Cellular Endocrinology. 446, p. 91-101 11 p.

Research output: Research - peer-reviewArticle

Induction of EAO in mice: responses to 2 elevated circulating levels of the activin-binding protein, follistatin

Nicholas, N., Muir, J. A., Hayward, S., Chen, J. L., Stanton, P. G., Gregorevic, P., de Kretser, D. M., Loveland, K. L., Bhushan, S., Meinhardt, A., Fijak, M. & Hedger, M. P. 1 Sep 2017 In : Reproduction. 154, 3, p. 293-305 13 p.

Research output: Research - peer-reviewArticle

Testicular activin and follistatin levels are elevated during the course of experimental autoimmune epididymo-orchitis in mice

Nicolas, N., Michel, V., Bhushan, S., Wahle, E., Hayward, S., Ludlow, H., De Kretser, D. M., Loveland, K., Schuppe, H. C., Meinhardt, A., Hedger, M. P. & Fijak, M. 13 Feb 2017 In : Scientific Reports. 7, 42391

Research output: Research - peer-reviewArticle

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2016

Activins in reproductive biology and beyond

Wijayarathna, J. M. & de Kretser, D. 2016 In : Human Reproduction Update. 22, 3, p. 342 - 357 16 p.

Research output: Research - peer-reviewArticle

Substantial Increases Occur in Serum Activins and Follistatin during Lung Transplantation

de Kretser, D. M., Bensley, J. G., Phillips, D. J., Levvey, B., Snell, G. I., Lin, E., Hedger, M. P. & O'Hehir, R. E. 2016 In : PLoS ONE. 11, 1, 16 p., e140948

Research output: Research - peer-reviewArticle

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Uropathogenic Escherichia coli causes fibrotic remodelling of the epididymis

Michel, V., Duan, Y., Stoschek, E., Bhushan, S., Middendorff, R., Young, J. M., Loveland, K. L., Kretser, D. M. D., Hedger, M. P. & Meinhardt, A. 1 Sep 2016 In : Journal of Pathology. 240, 1, p. 15-24 10 p.

Research output: Research - peer-reviewArticle

2015

Follistatin is essential for normal postnatal development and function of mouse oviduct and uterus

Holdsworth-Carson, S. J., Craythorn, R. G., Winnall, W. R., Dhaliwal, K., Genovese, R., Nowell, C. J., Rogers, P. A. W., de Kretser, D. M., Hedger, M. P. & Girling, J. E. 2015 In : Reproduction, Fertility and Development. 27, 7, p. 985 - 999 15 p.

Research output: Research - peer-reviewArticle

LRGUK-1 is required for basal body and manchette function during spermatogenesis and male fertility

Liu, Y., DeBoer, K. D., de Kretser, D. M., O'Donnell, L., O'Connor, A. E., Merriner, D. J., Okuda, H., Whittle, B., Jans, D. A., Efthymiadis, A., McLachlan, R. I., Ormandy, C. J., Goodnow, C. C., Jamsai, D. & O'Bryan, M. K. 2015 In : PLoS Genetics. 11, 3, 20 p., e1005090

Research output: Research - peer-reviewArticle

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Open Access
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2014

Serum activin A and B, and follistatin in critically ill patients with influenza A(H1N1) infection

Linko, R. T., Hedger, M. P., Pettila, V., Ruokonen, E. T., Ludlow, H. & de Kretser, D. M. 2014 In : BMC Infectious Diseases. 14, 1 (Art. ID: 253), p. 1 - 9 9 p.

Research output: Research - peer-reviewArticle

Open Access
2013

Expression patterns of activin, inhibin and follistatin variants in the adult male mouse reproductive tract suggest important roles in the epididymis and vas deferens

Winnall, W. R., Wu, H., Sarraj, M., Rogers, P. A., de Kretser, D. M., Girling, J. E. & Hedger, M. P. 2013 In : Reproduction, Fertility and Development. 25, 3, p. 570 - 580 11 p.

Research output: Research - peer-reviewArticle

Open Access
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Open Access
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Loss of the nuclear receptor corepressor SLIRP compromises male fertility

Colley, S. M., Wintle, L., Searles, R., Russell, V., Firman, R. C., Smith, S. J., DeBoer, K. D., Merriner, D. J., Genevieve, B., Bentel, J. M., Stuckey, B., Phillips, M. R., Simmons, L., de Kretser, D. M., O'Bryan, M. K. & Leedman, P. 2013 In : PLoS ONE. 8, 8 (Art. ID: e70700), p. 1 - 8 8 p.

Research output: Research - peer-reviewArticle

Open Access

Male reproductive health disorders among Aboriginal and Torres Strait Islander men: a hidden problem?

Adams, M. J., Collins, V. R., Dunne, M. P., de Kretser, D. M. & Holden, C. A. 2013 In : Medical Journal of Australia. 198, 1, p. 33 - 38 6 p.

Research output: Research - peer-reviewArticle

Serum activin A and B levels predict outcome in patients with acute respiratory failure: a prospective cohort study

de Kretser, D. M., Bensley, J. G. A., Pettila, V., Hedger, M. P., Hayward, S., Allan, C. A., McLachlan, R. I., Ludlow, H. & Phillips, D. J. 2013 In : Critical Care. 17, 5 (Art # R263), p. 1 - 13 13 p.

Research output: Research - peer-reviewArticle

Open Access
2012

An essential role for katanin p80 and microtubule severing in male gamete production

O'Donnell, L., Rhodes, D., Smith, S. J., Merriner, D. J., Clark, B. J., Borg, C. L., Whittle, B., O'Connor, A. E., Smith, L. B., McNally, F. J., de Kretser, D. M., Goodnow, C. C., Ormandy, C. J., Jamsai, D. & O'Bryan, M. K. 2012 In : PLoS Genetics. 8, 5 (Art. ID: e1002698), p. 1 - 12 12 p.

Research output: Research - peer-reviewArticle

Open Access

Progesterone stimulates expression of follistatin splice variants Fst288 and Fst315 in the mouse uterus

Craythorn, R., Winnall, W., Lederman, F., Gold, E., O'Connor, A., de Kretser, D., Hedger, M., Rogers, P. & Girling, J. 2012 In : Reproductive BioMedicine Online. 24, 3, p. 364 - 374 11 p.

Research output: Research - peer-reviewArticle

2011

A missense mutation in the transcription factor Foxo3a causes teratomas and oocyte abnormalities in mice

Youngson, N., Vickaryous, N., van der Horst, A., Epp, T., Harten, S., Fleming, J., Khanna, K. K., de Kretser, D. & Whitelaw, E. 2011 In : Mammalian Genome. 22, 3-4, p. 235 - 248 14 p.

Research output: Research - peer-reviewArticle

DNMT3L is a regulator of X chromosome compaction and post-meiotic gene transcription

Zamudio, N., Scott, H., Wolski, K., Lo, J. C., Law, C., Leong, D., Kinkel, S., Chong, S., Jolley, D., Smyth, G., de Kretser, D., Whitelaw, E. & O'Bryan, M. 2011 In : PLoS ONE. 6, 3, 12 p., e18276

Research output: Research - peer-reviewArticle

Open Access

TGF-β down under 2011-the experts interviewed!

de Kretser, D. & Henrik-Heldin, C. Oct 2011 In : Growth Factors. 29, 5, p. 161-162 2 p.

Research output: Other - peer-reviewArticle

The regulation and functions of activin and follistatin in inflammation and immunity

Hedger, M., Winnall, W., Phillips, D. J. & de Kretser, D. 2011 In : Vitamins and Hormones-Advances in Research and Applications. 85, p. 255 - 297 43 p.

Research output: Research - peer-reviewArticle

2010

Determinants of male health: The interaction of biological and social factors

de Kretser, D. M. 2010 In : Asian Journal of Andrology. 12, 3, p. 291 - 297 7 p.

Research output: Research - peer-reviewArticle

Determinants of male reproductive health disorders: The men in Australia telephone survey (MATeS)

Holden, C., McLachlan, R. I., Pitts, M., Cumming, R., Wittert, G., Ehsani, J., de Kretser, D. & Handelsman, D. 2010 In : BMC Public Health. 10, Art. No: 96, p. 1 - 9 9 p.

Research output: Research - peer-reviewArticle

Optimization of the expression of recombinant human activin A in the yeast Pichia pastoris

Fredericks, D., Clay, R., Warner, T., O'Connor, A., de Kretser, D. & Hearn, M. T. W. 2010 In : Biotechnology Progress. 26, 2, p. 372 - 383 12 p.

Research output: Research - peer-reviewArticle

2009

Activin and related proteins in inflammation: Not just interested bystanders

Phillips, D. J., de Kretser, D. M. & Hedger, M. P. 2009 In : Cytokine and Growth Factor Reviews. 20, 2, p. 153 - 164 12 p.

Research output: Research - peer-reviewArticle

A new 'total' activin B enzyme-linked immunosorbent assay (ELISA): development and validation for human samples

Ludlow, H., Phillips, D. J., Myers, M., McLachlan, R. I., de Kretser, D. M., Allan, C. A., Anderson, R. A., Groome, N. P., Hyvonen, M., Duncan, W. C. & Muttukrishna, S. 2009 In : Clinical Endocrinology. 71, 6, p. 867 - 873 7 p.

Research output: Research - peer-reviewArticle

2008

Evidence that androgens regulate early developmental events, prior to sexual differentiation

Goldman, D. R., de Kretser, D. M. & Morrison, J. R. 2008 In : Endocrinology. 149, 1, p. 5 - 14 10 p.

Research output: Research - peer-reviewArticle

Female infertility and disrupted angiogenesis are actions of specific follistatin isoforms

Lin, S-Y., Craythorn, R. G., O'Connor, A., Matzuk, M. M., Girling, J. E., Morrison, J. R. & de Kretser, D. M. 2008 In : Molecular Endocrinology. 22, epub ahead of print, p. 415 - 429 14 p.

Research output: Research - peer-reviewArticle

Molecular Identification of lyso-glycerophosphocholines as endogenous immunosuppressives in bovine and rat gonadal fluids

Foulds, L. M., Boysen, R. I., Crane, M., Yang, Y., Muir, J. A., Smith, A. I., de Kretser, D. M., Hearn, M. T. W. & Hedger, M. P. 2008 In : Biology of Reproduction. 79, 3, p. 525 - 536 12 p.

Research output: Research - peer-reviewArticle

Polymorphisms in the human cysteine-rich secretory protein 2 (CRISP2) gene in Australian Men

Jamsai, D., Reilly, A., Smith, S. J., Gibbs, G. M., Baker, H. W. G., McLachlan, R. I., de Kretser, D. M. & O'Bryan, M. K. 2008 In : Human Reproduction. 23, 9, p. 2151 - 2159 9 p.

Research output: Research - peer-reviewArticle

Sox8 is a critical regulator of adult sertoli cell function and male fertility

O'Bryan, M. K., Takada, S., Borg, C. L., Scott, G., Harada, S., Ray, M. K., Dai, Q., Wilhelm, D., de Kretser, D. M., Eddy, E. M., Koopman, P. A. & Mishina, Y. 2008 In : Developmental Biology. 316, 2, p. 359 - 370 12 p.

Research output: Research - peer-reviewArticle

Temporal expression of activin in acute burn wounds-From inflammatory cells to fibroblasts

McLean, C. A., Cleland, H. J., Moncrieff, N. J., Barton, R. J., de Kretser, D. M. & Phillips, D. J. 2008 In : Burns : Journal of the International Society for Burn Injuries. 34, p. 50 - 55 5 p.

Research output: Research - peer-reviewArticle

2007

Activin A is a critical component of the inflammatory response, and its binding protein, follistatin, reduces mortality in endotoxemia

Jones, K. L., Mansell, A. S., Patella, S., Scott, B. M., Hedger, M. P., de Kretser, D. M. & Phillips, D. J. 2007 In : Proceedings of the National Academy of Sciences. 104, 41, p. 16239 - 16244 6 p.

Research output: Research - peer-reviewArticle

Cysteine-rich secretory protein 2 binds to mitogen-activated protein kinase kinase kinase 11 in mouse sperm

Gibbs, G. M., Bianco, D. M., Jamsai, D., Herlihy, A., Ristevski, S., Aitken, R. J., de Kretser, D. M. & O'Bryan, M. K. 2007 In : Biology of Reproduction. 77, 1, p. 108 - 114 7 p.

Research output: Research - peer-reviewArticle

Histological evaluation of the human testis - approaches to optimizing the clinical value of the assessment: mini review

McLachlan, R. I., Rajpert-De Meyts, E., Hoei-Hansen, C. E., de Kretser, D. M. & Skakkebaek, N. E. 2007 In : Human Reproduction. 22, 1, p. 2 - 16 15 p.

Research output: Research - peer-reviewArticle

Modifiers of epigenetic reprogramming show paternal effects in the mouse

Chong, S., Vickaryous, N., Ashe, A., Zamudio, N. M., Youngson, N., Hemley, S., Stopka, T., Skoultchi, A., Matthews, J. M., Scott, H. S., de Kretser, D. M., O'Bryan, M. K., Blewitt, M. & Whitelaw, E. 2007 In : Nature Genetics. 39, 5, p. 614 - 622 9 p.

Research output: Research - peer-reviewArticle